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The map label for this gene is pip [H]

Identifier: 160873445

GI number: 160873445

Start: 365065

End: 366018

Strand: Direct

Name: pip [H]

Synonym: Sbal195_0320

Alternate gene names: 160873445

Gene position: 365065-366018 (Clockwise)

Preceding gene: 160873444

Following gene: 160873446

Centisome position: 6.83

GC content: 50.31

Gene sequence:

>954_bases
ATGCCTGAATCCTTTCCCCCTTTTATCCGCCGCGACTGGTTTAGCGTTGGCAATGGTCAGCAATTACATCTGGCACAATA
CGGAAATCCTCAAGGTATCCCGCTGTTGTATTTGCACGGTGGTCCGGGAGCGGGTTGTGATATCGGTGATTTAGCTTTAT
TTAATGGCGAACAATATTGGATTTTGCTGTTAGATCAACGAGGTTCTGGACAATCCTTGCCCTTTGGCGATTTAGCCCAT
AATCATCTTAATGGTTTGATCTGCGATATGGAGGCGATTCGCCTCGCGTTAGGTATTGAGCGCTGGTGTTTAGCGGGCGG
CTCTTTTGGGGCAACATTAGGCTTAATTTACAGCGGATTATTCCCCGAGCGGGTGATAGCGCAAGTGCTGTGGGCGCTAT
TTATTCCGTCTAAAGAAGGCATCGATTGGCTCTATGGCGCTGACGGCGCGGCAACATTGCAACCAGCGGCTTATCGACTC
TTCAGTGGCAATGCGTCCGTAGCACCATCGCTGACTGAACTTCTGGATTCATACCATCAAGGTTTGGCATCGGCCGATGA
AAACCTGCGGCACCATTTTGCGCGGCGTTGGGTTCAGTGGGAGCTAAAGCTCGCGGGGGCGAGATTGGTGTTGCCAAGAC
AGTTACCCGACCCAGTATTAGCGTTAGCGGATATCGAATTGCACTTTGCTCGGCATGATTACTTCAATGCCATGACTGTG
TTGCAACGCGTGACGCCTAGGGTGAAGGCGCGTAGTGTGTTATTGCAAGGAATGCAGGATGCGATTTGCCCAGCGGCGCT
ATTGCGCGATTTTTTGGCTGGGTTAGAGCATGCTATGACGATTCAATCTGTTGCCGACGGCGGACATATGCTCAATAGCG
AGTCGTTGTTTTTGGCAGTCACAGCAGAAATCCATGCTATGTGGTCGTGGATACATCAAAGGGAAATACAATGA

Upstream 100 bases:

>100_bases
TTCGTCGTCAGTATTAACGTCGGCAGAGGTGACGGCACTCAAGGCCGTGGCGAAATCGGAATGACATCCCTACACGGTTA
AGCAATGGCGATAACACTTA

Downstream 100 bases:

>100_bases
AAACATTGCTCATCAGTGCCAGTTTACTCGGATTAACCGCCTGTGCCGCTACGGCGCCCTCGCAAACCAGCGCGATTGAC
CCAGTGGTGGCTCAGGAGAC

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MPESFPPFIRRDWFSVGNGQQLHLAQYGNPQGIPLLYLHGGPGAGCDIGDLALFNGEQYWILLLDQRGSGQSLPFGDLAH
NHLNGLICDMEAIRLALGIERWCLAGGSFGATLGLIYSGLFPERVIAQVLWALFIPSKEGIDWLYGADGAATLQPAAYRL
FSGNASVAPSLTELLDSYHQGLASADENLRHHFARRWVQWELKLAGARLVLPRQLPDPVLALADIELHFARHDYFNAMTV
LQRVTPRVKARSVLLQGMQDAICPAALLRDFLAGLEHAMTIQSVADGGHMLNSESLFLAVTAEIHAMWSWIHQREIQ

Sequences:

>Translated_317_residues
MPESFPPFIRRDWFSVGNGQQLHLAQYGNPQGIPLLYLHGGPGAGCDIGDLALFNGEQYWILLLDQRGSGQSLPFGDLAH
NHLNGLICDMEAIRLALGIERWCLAGGSFGATLGLIYSGLFPERVIAQVLWALFIPSKEGIDWLYGADGAATLQPAAYRL
FSGNASVAPSLTELLDSYHQGLASADENLRHHFARRWVQWELKLAGARLVLPRQLPDPVLALADIELHFARHDYFNAMTV
LQRVTPRVKARSVLLQGMQDAICPAALLRDFLAGLEHAMTIQSVADGGHMLNSESLFLAVTAEIHAMWSWIHQREIQ
>Mature_316_residues
PESFPPFIRRDWFSVGNGQQLHLAQYGNPQGIPLLYLHGGPGAGCDIGDLALFNGEQYWILLLDQRGSGQSLPFGDLAHN
HLNGLICDMEAIRLALGIERWCLAGGSFGATLGLIYSGLFPERVIAQVLWALFIPSKEGIDWLYGADGAATLQPAAYRLF
SGNASVAPSLTELLDSYHQGLASADENLRHHFARRWVQWELKLAGARLVLPRQLPDPVLALADIELHFARHDYFNAMTVL
QRVTPRVKARSVLLQGMQDAICPAALLRDFLAGLEHAMTIQSVADGGHMLNSESLFLAVTAEIHAMWSWIHQREIQ

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 35009; Mature: 34877

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPESFPPFIRRDWFSVGNGQQLHLAQYGNPQGIPLLYLHGGPGAGCDIGDLALFNGEQYW
CCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCEEEECCCEEE
ILLLDQRGSGQSLPFGDLAHNHLNGLICDMEAIRLALGIERWCLAGGSFGATLGLIYSGL
EEEEECCCCCCCCCCHHHHHHHHCCEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
FPERVIAQVLWALFIPSKEGIDWLYGADGAATLQPAAYRLFSGNASVAPSLTELLDSYHQ
CHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHEEEECCCCCCCCHHHHHHHHHHH
GLASADENLRHHFARRWVQWELKLAGARLVLPRQLPDPVLALADIELHFARHDYFNAMTV
HHHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCCCCHHEEEEHHEEEEHHHHHHHHHHH
LQRVTPRVKARSVLLQGMQDAICPAALLRDFLAGLEHAMTIQSVADGGHMLNSESLFLAV
HHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEE
TAEIHAMWSWIHQREIQ
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PESFPPFIRRDWFSVGNGQQLHLAQYGNPQGIPLLYLHGGPGAGCDIGDLALFNGEQYW
CCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCEEEECCCEEE
ILLLDQRGSGQSLPFGDLAHNHLNGLICDMEAIRLALGIERWCLAGGSFGATLGLIYSGL
EEEEECCCCCCCCCCHHHHHHHHCCEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
FPERVIAQVLWALFIPSKEGIDWLYGADGAATLQPAAYRLFSGNASVAPSLTELLDSYHQ
CHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHEEEECCCCCCCCHHHHHHHHHHH
GLASADENLRHHFARRWVQWELKLAGARLVLPRQLPDPVLALADIELHFARHDYFNAMTV
HHHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCCCCHHEEEEHHEEEEHHHHHHHHHHH
LQRVTPRVKARSVLLQGMQDAICPAALLRDFLAGLEHAMTIQSVADGGHMLNSESLFLAV
HHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEE
TAEIHAMWSWIHQREIQ
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]