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The map label for this gene is yycF [H]

Identifier: 160873434

GI number: 160873434

Start: 351240

End: 351947

Strand: Direct

Name: yycF [H]

Synonym: Sbal195_0309

Alternate gene names: 160873434

Gene position: 351240-351947 (Clockwise)

Preceding gene: 160873433

Following gene: 160873435

Centisome position: 6.57

GC content: 41.1

Gene sequence:

>708_bases
ATGAAAACCAAAATTCTCATTGTAGAGGATGATTTGCCTTTAGCTGAGTCTATTCAGGAGTACCTTAACTATGAAGGTTA
CCAAGTAGAGATAATCTCAAACGGCGTGCTAGCAGTATCGAGGATTCTTGAATGGCAGCCCGCACTGGTGATACTCGACA
TCATGTTACCGCAAAAAGACGGCTTGAGTGTATGCCGAGAAGTAAGGCCGCAATATAACGGCTATATTTTGATGTTTACC
GCGCGAGGAGAAGAAATAGATCAAATTGTTGGGCTTGAAATTGGCGCAGATGATTACTTACTTAAACCAGTCAAACCTCG
TATGTTGCTGGCTAAAATCAAAGCGTTTTTAAGGCGAGATAGATTGGCCGAATCGATTGCTGAGAACCAGCAGGTAAGCG
AATATATTAGTTTTGGCCAATTAGCGATCAATACCCAAAAGCGAAGCGTAACCTTAGCAGATGTAGCGATAAAGCTTACG
GATGGAGAGTATGATCTGCTGATCACTTTAGCTAAAAATGCCGGAAATATATTGTCTCGTAACGATATAGTCGAACAAGT
AAAAGGCTATTATTACGACGGTATAGAGCGCGGTGTTGATAATCATATTTGTCAGCTTAGAAAAAAACTCGGCGATGACG
CGCGTAATCCATTTAAGATAAAAACGATTCGTTCAAAAGGGTATTTATTTGTCTCTAGCGGCTGGTGA

Upstream 100 bases:

>100_bases
TCGGCGAGCGTTAACGCGTCAGCTTTAGGAGGCGCTCGTTTTGTCCTCAGTTGGCCAGACAAGAAGTTATGACGTATAGC
AGGTTAAGGAGTAGGCGATA

Downstream 100 bases:

>100_bases
TATTGATTTTTTTGATATTAGTTACCGAGATGGATGACCGCTATTTATCTGGCTGGCAATAGAGTTTTCTATCTTAAACC
AAATTTTCATTGTTTTAAAA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MKTKILIVEDDLPLAESIQEYLNYEGYQVEIISNGVLAVSRILEWQPALVILDIMLPQKDGLSVCREVRPQYNGYILMFT
ARGEEIDQIVGLEIGADDYLLKPVKPRMLLAKIKAFLRRDRLAESIAENQQVSEYISFGQLAINTQKRSVTLADVAIKLT
DGEYDLLITLAKNAGNILSRNDIVEQVKGYYYDGIERGVDNHICQLRKKLGDDARNPFKIKTIRSKGYLFVSSGW

Sequences:

>Translated_235_residues
MKTKILIVEDDLPLAESIQEYLNYEGYQVEIISNGVLAVSRILEWQPALVILDIMLPQKDGLSVCREVRPQYNGYILMFT
ARGEEIDQIVGLEIGADDYLLKPVKPRMLLAKIKAFLRRDRLAESIAENQQVSEYISFGQLAINTQKRSVTLADVAIKLT
DGEYDLLITLAKNAGNILSRNDIVEQVKGYYYDGIERGVDNHICQLRKKLGDDARNPFKIKTIRSKGYLFVSSGW
>Mature_235_residues
MKTKILIVEDDLPLAESIQEYLNYEGYQVEIISNGVLAVSRILEWQPALVILDIMLPQKDGLSVCREVRPQYNGYILMFT
ARGEEIDQIVGLEIGADDYLLKPVKPRMLLAKIKAFLRRDRLAESIAENQQVSEYISFGQLAINTQKRSVTLADVAIKLT
DGEYDLLITLAKNAGNILSRNDIVEQVKGYYYDGIERGVDNHICQLRKKLGDDARNPFKIKTIRSKGYLFVSSGW

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=40.7725321888412, Blast_Score=171, Evalue=4e-44,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=40.4255319148936, Blast_Score=170, Evalue=6e-44,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=35.4978354978355, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=36.7256637168142, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=33.9130434782609, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=33.7719298245614, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI87082012, Length=232, Percent_Identity=33.6206896551724, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=34.1991341991342, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786599, Length=235, Percent_Identity=31.4893617021277, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=34.9344978165939, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=32.3008849557522, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=31.4655172413793, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1786911, Length=233, Percent_Identity=29.6137339055794, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786838, Length=135, Percent_Identity=32.5925925925926, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26658; Mature: 26658

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKILIVEDDLPLAESIQEYLNYEGYQVEIISNGVLAVSRILEWQPALVILDIMLPQKD
CCEEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCEEEEEEECCCCC
GLSVCREVRPQYNGYILMFTARGEEIDQIVGLEIGADDYLLKPVKPRMLLAKIKAFLRRD
CHHHHHHCCCCCCCEEEEEEECCCCHHHHCCEEECCCCCEECCCCHHHHHHHHHHHHHHH
RLAESIAENQQVSEYISFGQLAINTQKRSVTLADVAIKLTDGEYDLLITLAKNAGNILSR
HHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEEEEEEEECCCEEEEEEEECCCCCCCCH
NDIVEQVKGYYYDGIERGVDNHICQLRKKLGDDARNPFKIKTIRSKGYLFVSSGW
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEECCC
>Mature Secondary Structure
MKTKILIVEDDLPLAESIQEYLNYEGYQVEIISNGVLAVSRILEWQPALVILDIMLPQKD
CCEEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCEEEEEEECCCCC
GLSVCREVRPQYNGYILMFTARGEEIDQIVGLEIGADDYLLKPVKPRMLLAKIKAFLRRD
CHHHHHHCCCCCCCEEEEEEECCCCHHHHCCEEECCCCCEECCCCHHHHHHHHHHHHHHH
RLAESIAENQQVSEYISFGQLAINTQKRSVTLADVAIKLTDGEYDLLITLAKNAGNILSR
HHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEEEEEEEECCCEEEEEEEECCCCCCCCH
NDIVEQVKGYYYDGIERGVDNHICQLRKKLGDDARNPFKIKTIRSKGYLFVSSGW
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]