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The map label for this gene is ribB

Identifier: 160873265

GI number: 160873265

Start: 163524

End: 164177

Strand: Reverse

Name: ribB

Synonym: Sbal195_0139

Alternate gene names: 160873265

Gene position: 164177-163524 (Counterclockwise)

Preceding gene: 160873270

Following gene: 160873264

Centisome position: 3.07

GC content: 52.14

Gene sequence:

>654_bases
ATGAATCAGTCTTTACTTGCTCCTTTTGGTACTGCTATCGAACGCGTTGAAGCGGGTCTTAATGCCCTGCGTCAAGGCCA
AGGTGTGTTAGTTGTCGATGACGAAGATAGAGAAAACGAAGGCGATTTAATTTTCGCTGCCGAGACACTGACGAACGCCC
AAATGGCCATGCTCATCCGTGAATGTAGCGGTATTGTTTGCCTGTGTTTACCCGATGAAAAAGTCAAAGCCCTCGAACTG
CCTGCTATGGTCGAGCACAACTCGAGCCAATACGGCACAGCTTTTACTGTGAGTATCGAAGCAACTGTCGGTGTAACGAC
TGGGGTTTCTGCCGCTGACCGCGTGACCACCATTAAAGCCGCGATTGCCGACAACGCTAAACCAAGCGATCTCGCTCGCC
CAGGCCATGTGTATCCACTTCGCGCCCAACCGGGCGGCGTGTTAACTCGCCGCGGCCACACCGAAGGCACGATCGATTTA
GTGCAACTCGCTGGCTTAAAACCCGCTGGTGTATTGTGTGAAGTCACTAACCCAGACGGTACTATGGCGCGTTTACCCGA
AATTATCGCCTTCGGCGCACTGCACAATATGCCTGTGCTGACGATTGAAGACATAGTGGTCTACCGTAAATCGCTACTGG
CGAAGGTCGGTTAA

Upstream 100 bases:

>100_bases
ATTGCTACAGCAAAATCGAGCCATTAGGTTTGATTAGGTTGTATTTCTGCACGCCCTGATTCTGGATATTCCAATGTCGT
ATTTTTTAAGGATATTAACC

Downstream 100 bases:

>100_bases
GTCAGACTTCAATGGCCTAAACTTAGGTCATTAATTTAAGACGAAGGGACGTTTCGCTGCGGCAAACGTCCTTTTTATTG
AGCATTATTTGCAACCCAAC

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MNQSLLAPFGTAIERVEAGLNALRQGQGVLVVDDEDRENEGDLIFAAETLTNAQMAMLIRECSGIVCLCLPDEKVKALEL
PAMVEHNSSQYGTAFTVSIEATVGVTTGVSAADRVTTIKAAIADNAKPSDLARPGHVYPLRAQPGGVLTRRGHTEGTIDL
VQLAGLKPAGVLCEVTNPDGTMARLPEIIAFGALHNMPVLTIEDIVVYRKSLLAKVG

Sequences:

>Translated_217_residues
MNQSLLAPFGTAIERVEAGLNALRQGQGVLVVDDEDRENEGDLIFAAETLTNAQMAMLIRECSGIVCLCLPDEKVKALEL
PAMVEHNSSQYGTAFTVSIEATVGVTTGVSAADRVTTIKAAIADNAKPSDLARPGHVYPLRAQPGGVLTRRGHTEGTIDL
VQLAGLKPAGVLCEVTNPDGTMARLPEIIAFGALHNMPVLTIEDIVVYRKSLLAKVG
>Mature_217_residues
MNQSLLAPFGTAIERVEAGLNALRQGQGVLVVDDEDRENEGDLIFAAETLTNAQMAMLIRECSGIVCLCLPDEKVKALEL
PAMVEHNSSQYGTAFTVSIEATVGVTTGVSAADRVTTIKAAIADNAKPSDLARPGHVYPLRAQPGGVLTRRGHTEGTIDL
VQLAGLKPAGVLCEVTNPDGTMARLPEIIAFGALHNMPVLTIEDIVVYRKSLLAKVG

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family

Homologues:

Organism=Escherichia coli, GI1789420, Length=211, Percent_Identity=69.6682464454976, Blast_Score=308, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6320695, Length=214, Percent_Identity=41.1214953271028, Blast_Score=169, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIBB_SHEB2 (B8E3W7)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002356102.1
- ProteinModelPortal:   B8E3W7
- SMR:   B8E3W7
- GeneID:   7086740
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_0138
- HOGENOM:   HBG735778
- OMA:   RGHTEAT
- ProtClustDB:   PRK03353
- HAMAP:   MF_00180
- InterPro:   IPR017945
- InterPro:   IPR000422
- Gene3D:   G3DSA:3.90.870.10
- TIGRFAMs:   TIGR00506

Pfam domain/function: PF00926 DHBP_synthase; SSF55821 DHBP_synth_RibB-like_a/b_dom

EC number: =4.1.99.12

Molecular weight: Translated: 22943; Mature: 22943

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: BINDING 42-42 BINDING 174-174

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQSLLAPFGTAIERVEAGLNALRQGQGVLVVDDEDRENEGDLIFAAETLTNAQMAMLIR
CCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEHHHCCHHHHHHHH
ECSGIVCLCLPDEKVKALELPAMVEHNSSQYGTAFTVSIEATVGVTTGVSAADRVTTIKA
HCCCEEEEEECCCCCCEEECCHHCCCCCCCCCEEEEEEEEEEEEEECCCCCHHHHHEEEE
AIADNAKPSDLARPGHVYPLRAQPGGVLTRRGHTEGTIDLVQLAGLKPAGVLCEVTNPDG
HHCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCEEEEEECCCCCCCEEEEEECCCC
TMARLPEIIAFGALHNMPVLTIEDIVVYRKSLLAKVG
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQSLLAPFGTAIERVEAGLNALRQGQGVLVVDDEDRENEGDLIFAAETLTNAQMAMLIR
CCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEHHHCCHHHHHHHH
ECSGIVCLCLPDEKVKALELPAMVEHNSSQYGTAFTVSIEATVGVTTGVSAADRVTTIKA
HCCCEEEEEECCCCCCEEECCHHCCCCCCCCCEEEEEEEEEEEEEECCCCCHHHHHEEEE
AIADNAKPSDLARPGHVYPLRAQPGGVLTRRGHTEGTIDLVQLAGLKPAGVLCEVTNPDG
HHCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCEEEEEECCCCCCCEEEEEECCCC
TMARLPEIIAFGALHNMPVLTIEDIVVYRKSLLAKVG
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA