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The map label for this gene is ssb1 [H]

Identifier: 159901474

GI number: 159901474

Start: 6297558

End: 6298058

Strand: Direct

Name: ssb1 [H]

Synonym: Haur_4963

Alternate gene names: 159901474

Gene position: 6297558-6298058 (Clockwise)

Preceding gene: 159901473

Following gene: 159901475

Centisome position: 99.23

GC content: 53.89

Gene sequence:

>501_bases
GTGGCGAAAGATTTAAATAAAGTGATGATTATTGGTCGCTTGGGCAAAGATCCTGAAATGCGTTTTACGCCACAAGGAAC
ACCCGTGACCAACTTCACTGTCGCCGCTGGTCGTCAGTGGAAAGACCCCAATGGCGAGACCCGCGATGAAACCGAATGGT
TTTCGGTCGTGGTCTGGAACAAATTGGCCGAGATCTGTAATCAGTATCTGACCAAAGGCAGCCGCGTCTATATCGAGGGT
CGGCTGCAAACCCGCTCGTGGGACGACGATAGCGGCCAGAAGCGCTTTCGTACCGAAGTGGTCGCCAGCGATATGATCAT
TCTTGATCGTACCGATCAACAGCAAGGCCAAGGCCAGTCGCGCAGCGGCGGCTACCAAGCTGGAGGCAATCAACGCCCAC
CCCGCGATAATTCCGCCAATGATTATAATCGTGGTGGCAGCTACGGTGGTGGCGCTGGCTACAACGAGCCTGATATCGGC
GATGACGATATCCCATTCTAA

Upstream 100 bases:

>100_bases
GTGACTGAAGTCGAACGCCACTTGAAGTTGGCTCCACAAATCCTGCGCTATTTGTTGATCCGCGACGAAACCAAGCGCTA
AAACCAACGGGGAGGAAACC

Downstream 100 bases:

>100_bases
ACACTGTTGAATTAGAATTACTAGAACATACAAGGAGCCGTTCGCATGTCAGATCAACGCCGTAAGTCGGCAGGTCGCCG
CAAATACACACCCCGTCGCA

Product: single-strand binding protein

Products: NA

Alternate protein names: SSB 1; Helix-destabilizing protein 1 [H]

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MAKDLNKVMIIGRLGKDPEMRFTPQGTPVTNFTVAAGRQWKDPNGETRDETEWFSVVVWNKLAEICNQYLTKGSRVYIEG
RLQTRSWDDDSGQKRFRTEVVASDMIILDRTDQQQGQGQSRSGGYQAGGNQRPPRDNSANDYNRGGSYGGGAGYNEPDIG
DDDIPF

Sequences:

>Translated_166_residues
MAKDLNKVMIIGRLGKDPEMRFTPQGTPVTNFTVAAGRQWKDPNGETRDETEWFSVVVWNKLAEICNQYLTKGSRVYIEG
RLQTRSWDDDSGQKRFRTEVVASDMIILDRTDQQQGQGQSRSGGYQAGGNQRPPRDNSANDYNRGGSYGGGAGYNEPDIG
DDDIPF
>Mature_165_residues
AKDLNKVMIIGRLGKDPEMRFTPQGTPVTNFTVAAGRQWKDPNGETRDETEWFSVVVWNKLAEICNQYLTKGSRVYIEGR
LQTRSWDDDSGQKRFRTEVVASDMIILDRTDQQQGQGQSRSGGYQAGGNQRPPRDNSANDYNRGGSYGGGAGYNEPDIGD
DDIPF

Specific function: This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair [H]

COG id: COG0629

COG function: function code L; Single-stranded DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SSB domain [H]

Homologues:

Organism=Homo sapiens, GI4507231, Length=123, Percent_Identity=30.0813008130081, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1790494, Length=103, Percent_Identity=50.4854368932039, Blast_Score=116, Evalue=6e-28,
Organism=Drosophila melanogaster, GI85725234, Length=109, Percent_Identity=33.0275229357798, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24647376, Length=109, Percent_Identity=33.0275229357798, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: 1622 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000424
- InterPro:   IPR011344 [H]

Pfam domain/function: PF00436 SSB [H]

EC number: NA

Molecular weight: Translated: 18558; Mature: 18426

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50935 SSB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDLNKVMIIGRLGKDPEMRFTPQGTPVTNFTVAAGRQWKDPNGETRDETEWFSVVVWN
CCCCCCEEEEEEECCCCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
KLAEICNQYLTKGSRVYIEGRLQTRSWDDDSGQKRFRTEVVASDMIILDRTDQQQGQGQS
HHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCC
RSGGYQAGGNQRPPRDNSANDYNRGGSYGGGAGYNEPDIGDDDIPF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKDLNKVMIIGRLGKDPEMRFTPQGTPVTNFTVAAGRQWKDPNGETRDETEWFSVVVWN
CCCCCEEEEEEECCCCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
KLAEICNQYLTKGSRVYIEGRLQTRSWDDDSGQKRFRTEVVASDMIILDRTDQQQGQGQS
HHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCC
RSGGYQAGGNQRPPRDNSANDYNRGGSYGGGAGYNEPDIGDDDIPF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]