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The map label for this gene is phoR [H]

Identifier: 159901387

GI number: 159901387

Start: 6211248

End: 6211973

Strand: Reverse

Name: phoR [H]

Synonym: Haur_4876

Alternate gene names: 159901387

Gene position: 6211973-6211248 (Counterclockwise)

Preceding gene: 159901390

Following gene: 159901384

Centisome position: 97.88

GC content: 53.17

Gene sequence:

>726_bases
ATGAGCCGCGCCAGCAGCTTTGAACGAGCCACACTCGACCCGTTTTACCACGAGCTTCGCACCTCGCTGACCTTGATCCA
AACCTGTACCGATTTGTTGATGCATGCCGACCAAATTGGGCAGGCCGATTTACGCAATTTTTTACAAATTATCCGGCGTG
GTGGCACTCGGATTGATCGGCTTGTGCGGGATTATATTTTGTTGGCCAAGGGTGAGTATGGGGTTTTGAGCGAAGAGAAA
GTCGCTCAACCAACCTCAGTTTTGCCCCCACTCAATTTAGCCTTGCTTGAGGTTCGCGCCGAAAGTAATGATCGTGGGGT
CGAGATTGTTAGCGATCTGCCCGAAACGATGCCTTTGGTATTGGCCAACCCCGACCATTTACGCCTGATTATCGAGCGTT
TGTTGAGCGTAGCGTTGCGGTTTGTGCGCAATTCAGGCGATGCAGTTGTGGTGCAAACCCGTACCATGCCCGATAGCGTG
GCGGTGGTCTTTACGGTCGAAGGTGTGCCCCTGACCGACGAGGATTTACCACGAATTTTCGATCGCTTCTTCGTGCCGCA
AAATTTGCCACTCTCCCGCGAGCAACATGGCTTGGGCTTAGATTTGCCAGTCGTCAAATCGTTGGTTGAGCTGTATGGCG
GCAAGGTGGCGATCGAGCGGTTGGCCAAGGGCAATGTGTTTGCCTTTACGATTCCTCGGGCCGAGCCAGAAACCAGCCGT
AGCTAA

Upstream 100 bases:

>100_bases
AGCCCTCACTGTGTAAGTTATTTTTGCTATGATGCCCAGCTACGCTTAGCATTATTTTGACGTGTTAGATGGGAAACACG
GCGCACCCAAGGAGTTACCG

Downstream 100 bases:

>100_bases
AATAATTCAGCGCAGTCGTGATGACTGCGCTGTTTTTTAGGCCTGCAATACCCGATCAAAAAACGCCAAAATCGTTTGGT
TAATCTGTTGAAGATAGGGG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MSRASSFERATLDPFYHELRTSLTLIQTCTDLLMHADQIGQADLRNFLQIIRRGGTRIDRLVRDYILLAKGEYGVLSEEK
VAQPTSVLPPLNLALLEVRAESNDRGVEIVSDLPETMPLVLANPDHLRLIIERLLSVALRFVRNSGDAVVVQTRTMPDSV
AVVFTVEGVPLTDEDLPRIFDRFFVPQNLPLSREQHGLGLDLPVVKSLVELYGGKVAIERLAKGNVFAFTIPRAEPETSR
S

Sequences:

>Translated_241_residues
MSRASSFERATLDPFYHELRTSLTLIQTCTDLLMHADQIGQADLRNFLQIIRRGGTRIDRLVRDYILLAKGEYGVLSEEK
VAQPTSVLPPLNLALLEVRAESNDRGVEIVSDLPETMPLVLANPDHLRLIIERLLSVALRFVRNSGDAVVVQTRTMPDSV
AVVFTVEGVPLTDEDLPRIFDRFFVPQNLPLSREQHGLGLDLPVVKSLVELYGGKVAIERLAKGNVFAFTIPRAEPETSR
S
>Mature_240_residues
SRASSFERATLDPFYHELRTSLTLIQTCTDLLMHADQIGQADLRNFLQIIRRGGTRIDRLVRDYILLAKGEYGVLSEEKV
AQPTSVLPPLNLALLEVRAESNDRGVEIVSDLPETMPLVLANPDHLRLIIERLLSVALRFVRNSGDAVVVQTRTMPDSVA
VVFTVEGVPLTDEDLPRIFDRFFVPQNLPLSREQHGLGLDLPVVKSLVELYGGKVAIERLAKGNVFAFTIPRAEPETSRS

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=226, Percent_Identity=33.1858407079646, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=25.8474576271186, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 26896; Mature: 26765

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRASSFERATLDPFYHELRTSLTLIQTCTDLLMHADQIGQADLRNFLQIIRRGGTRIDR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHH
LVRDYILLAKGEYGVLSEEKVAQPTSVLPPLNLALLEVRAESNDRGVEIVSDLPETMPLV
HHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCEEEEEEECCCCCCCHHHHHCCCHHCCEE
LANPDHLRLIIERLLSVALRFVRNSGDAVVVQTRTMPDSVAVVFTVEGVPLTDEDLPRIF
EECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHH
DRFFVPQNLPLSREQHGLGLDLPVVKSLVELYGGKVAIERLAKGNVFAFTIPRAEPETSR
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCCCCC
S
C
>Mature Secondary Structure 
SRASSFERATLDPFYHELRTSLTLIQTCTDLLMHADQIGQADLRNFLQIIRRGGTRIDR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHH
LVRDYILLAKGEYGVLSEEKVAQPTSVLPPLNLALLEVRAESNDRGVEIVSDLPETMPLV
HHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCEEEEEEECCCCCCCHHHHHCCCHHCCEE
LANPDHLRLIIERLLSVALRFVRNSGDAVVVQTRTMPDSVAVVFTVEGVPLTDEDLPRIF
EECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHH
DRFFVPQNLPLSREQHGLGLDLPVVKSLVELYGGKVAIERLAKGNVFAFTIPRAEPETSR
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]