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The map label for this gene is ywlC [H]

Identifier: 159901360

GI number: 159901360

Start: 6179824

End: 6180447

Strand: Reverse

Name: ywlC [H]

Synonym: Haur_4849

Alternate gene names: 159901360

Gene position: 6180447-6179824 (Counterclockwise)

Preceding gene: 159901361

Following gene: 159901359

Centisome position: 97.38

GC content: 52.88

Gene sequence:

>624_bases
ATGAACACCAATGTTATCGATTTTGATGATGCCGGTTTGGCCTTAGCCTTGGCGCAATTACAGCAAGGCCAAATTCTCTG
TTTTCCCACCGATACCGTCTATGGTATTGGTGGCTCAGCCTTGGATGAAGCAGCGATTGCCCAAGTTTTTCAGGCCAAAG
CACGGCCAGCCACGGTTGCGCTACCGATGTTGCTGGCTGATTTGGATGATCTATCCAAGGTTGCCCGTGATATTCCCGAT
TTGGCGTGGCGTTTGGCTGAGGCTTGGTGGCCAGGTGGCTTGACCTTAGTCTTGCCAGCGGTCGCGCAGCTACCGCAATT
ATTAACTGCTGGCAAAGCGACGATTGCCGTGCGAGTGCCAAACCATGGGCAATTGCGCAACTTGATTCGCCAATTTGGCA
CGCCAATCGCTGGAACCAGTGCTAATTTGCATGGTAAAGCAACGCCGAATACCGCGCAGGCTGTGGCTGAACAATTGGCT
GGGCGTGTGCCATTGGTGCTTGATGGTGGGTTTGCAATGGGCGAACAACCCTCAACGATTGTCGATCTCAGTGGTGAGCA
ACCGACAATTTTGCGTCAAGGGGTTATTTCAGCGGCCCAACTCAGCCCTTGGTTGGAAGCCTAA

Upstream 100 bases:

>100_bases
TGTTGCATCATGCCCAAGCTGGCACACTTGATCGGCGCATCGGCTGGGAATTGGGAATTGTCGGCGCAGCCGTCTTTGTG
ATTTTGACCGCAACAACCTT

Downstream 100 bases:

>100_bases
ACCGCTTGAGGGCTGAGCCATAATCGCGGCACATTTGCTAGAATGCTTGGGCAATGGGGGCGGCATAGGCAGTCCATCAG
TTAAAGCCAACGTGCCATGA

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MNTNVIDFDDAGLALALAQLQQGQILCFPTDTVYGIGGSALDEAAIAQVFQAKARPATVALPMLLADLDDLSKVARDIPD
LAWRLAEAWWPGGLTLVLPAVAQLPQLLTAGKATIAVRVPNHGQLRNLIRQFGTPIAGTSANLHGKATPNTAQAVAEQLA
GRVPLVLDGGFAMGEQPSTIVDLSGEQPTILRQGVISAAQLSPWLEA

Sequences:

>Translated_207_residues
MNTNVIDFDDAGLALALAQLQQGQILCFPTDTVYGIGGSALDEAAIAQVFQAKARPATVALPMLLADLDDLSKVARDIPD
LAWRLAEAWWPGGLTLVLPAVAQLPQLLTAGKATIAVRVPNHGQLRNLIRQFGTPIAGTSANLHGKATPNTAQAVAEQLA
GRVPLVLDGGFAMGEQPSTIVDLSGEQPTILRQGVISAAQLSPWLEA
>Mature_207_residues
MNTNVIDFDDAGLALALAQLQQGQILCFPTDTVYGIGGSALDEAAIAQVFQAKARPATVALPMLLADLDDLSKVARDIPD
LAWRLAEAWWPGGLTLVLPAVAQLPQLLTAGKATIAVRVPNHGQLRNLIRQFGTPIAGTSANLHGKATPNTAQAVAEQLA
GRVPLVLDGGFAMGEQPSTIVDLSGEQPTILRQGVISAAQLSPWLEA

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=179, Percent_Identity=31.8435754189944, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI87081864, Length=192, Percent_Identity=27.6041666666667, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI2367210, Length=197, Percent_Identity=31.4720812182741, Blast_Score=86, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17537239, Length=182, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321269, Length=194, Percent_Identity=34.020618556701, Blast_Score=109, Evalue=3e-25,
Organism=Drosophila melanogaster, GI78707274, Length=189, Percent_Identity=31.7460317460317, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 21656; Mature: 21656

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTNVIDFDDAGLALALAQLQQGQILCFPTDTVYGIGGSALDEAAIAQVFQAKARPATVA
CCCCEECCCCCCHHHHHHHHHCCCEEEEECCCEEECCCHHHHHHHHHHHHHHCCCCHHHH
LPMLLADLDDLSKVARDIPDLAWRLAEAWWPGGLTLVLPAVAQLPQLLTAGKATIAVRVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC
NHGQLRNLIRQFGTPIAGTSANLHGKATPNTAQAVAEQLAGRVPLVLDGGFAMGEQPSTI
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCEE
VDLSGEQPTILRQGVISAAQLSPWLEA
EEECCCCCHHHHHHHHHHHHCCHHHCC
>Mature Secondary Structure
MNTNVIDFDDAGLALALAQLQQGQILCFPTDTVYGIGGSALDEAAIAQVFQAKARPATVA
CCCCEECCCCCCHHHHHHHHHCCCEEEEECCCEEECCCHHHHHHHHHHHHHHCCCCHHHH
LPMLLADLDDLSKVARDIPDLAWRLAEAWWPGGLTLVLPAVAQLPQLLTAGKATIAVRVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC
NHGQLRNLIRQFGTPIAGTSANLHGKATPNTAQAVAEQLAGRVPLVLDGGFAMGEQPSTI
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCEE
VDLSGEQPTILRQGVISAAQLSPWLEA
EEECCCCCHHHHHHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]