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The map label for this gene is yngJ [H]

Identifier: 159901273

GI number: 159901273

Start: 6067078

End: 6068238

Strand: Direct

Name: yngJ [H]

Synonym: Haur_4761

Alternate gene names: 159901273

Gene position: 6067078-6068238 (Clockwise)

Preceding gene: 159901262

Following gene: 159901274

Centisome position: 95.6

GC content: 50.9

Gene sequence:

>1161_bases
ATGTCGCTCTATTTTAACGCTGAGCATGAACTGTTTCGCCAAACGATCCGGCGGTTTGTTGAACGCGAAATTAACCCCTT
TGTCGAGCAATGGGAGCATGAGCGGGCTTTTCCTGGCCATGCCTTATTCAAAAAATTAGGTGAATTAGATGCGTTGGGTG
TTTCGTACCCCGAAGCCTATGGTGGTGCAGGCTTAGATTATTGGTATAACGTGGTGTTGGCCGAGGAATTAGGCTATGCT
GATTGTGGTGGCGTGCCCATGGCGATTGCGGTGCATACCGATATGGCTACGCCCGCCTTGGCCGAATTTGGCAGCGACGA
GTTACGTCAGCGCTTTTTGGCTCCCGCAATTCGTGGCGAAATGATTGCGGCGGTGGCAATTTCCGAGCCTGATGCTGGCT
CCGATGTCGCGGCGATTCGCACGCGGGCGGTACGCGATGGCGATGAGTATGTGATCAACGGCCATAAAATGTGGATCACC
AATGGTACACAGGCCGATTTTATTACGCTTTTGGCCCGCACCAGCGACGAACCTGGCTATAAATCCATGTCGTTGCTGAT
TGTCCCAACCAACACCCCAGGCTTTCATGTTTCCAAGAAATTAGAGAAATTGGGCAATCATTCCAGCGATACTGCATTGT
TGGCGTTTGACGATGTGCGCGTGCCAGTCGCCAATCGCATCGGTGATGAAGGCCAAGGCTTTGTACTGCAAATGCAGCAA
TTTCAAAAAGAACGCTTGATTGGCGCGGTTTCGGCGGTTTCGGCCATGGAACGCATCGTTGAAATGACCAGCCACTATTG
CCGTGAGCGCCAAACATTTGGCAAGCCCTTGATTGAAAACCAATATATTCAATTTCGCTTGGCTGAGTTATTGACCGAGA
TTGAGGCATTGCGCCAACTCAATTATCACTGCACCCGTCTGCTTTTGGCAGGCCACGACATCACCAAAGAGGTTTCAATG
GCCAAACTCAAGGCTGGGCGTTTGGCTCGTGAAGTTGCTGATACATGTTTACAATTCCACGGCGGCATGGGCTATGTTGA
AGAATACCCGATGGCCCGCTATTTTCGTGATGCCCGTTTGCTGTCAATCGGCGGTGGCGCTGATGAAATTATGCTGGGAA
TTATCGCCAAATATGCGGGTTTGTCGCGCAAACGTGGTTAG

Upstream 100 bases:

>100_bases
TAGAACGCATAACCTACCTCACTTAATACCAAGCCAACCACTTAAAGGGCCTATGCTACAATCGGGCTACGATTGCGATG
CCCAAAGCAAGGAGGCTGTG

Downstream 100 bases:

>100_bases
TTGAATGTAGTGTTACGGCTATATTCGTTGTTCTTTCGGTAGTTAAACCTGCCACTTTTGCTTGGCAAGTATCGACCTGC
ATGATTAAAAGCATCGCGTA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MSLYFNAEHELFRQTIRRFVEREINPFVEQWEHERAFPGHALFKKLGELDALGVSYPEAYGGAGLDYWYNVVLAEELGYA
DCGGVPMAIAVHTDMATPALAEFGSDELRQRFLAPAIRGEMIAAVAISEPDAGSDVAAIRTRAVRDGDEYVINGHKMWIT
NGTQADFITLLARTSDEPGYKSMSLLIVPTNTPGFHVSKKLEKLGNHSSDTALLAFDDVRVPVANRIGDEGQGFVLQMQQ
FQKERLIGAVSAVSAMERIVEMTSHYCRERQTFGKPLIENQYIQFRLAELLTEIEALRQLNYHCTRLLLAGHDITKEVSM
AKLKAGRLAREVADTCLQFHGGMGYVEEYPMARYFRDARLLSIGGGADEIMLGIIAKYAGLSRKRG

Sequences:

>Translated_386_residues
MSLYFNAEHELFRQTIRRFVEREINPFVEQWEHERAFPGHALFKKLGELDALGVSYPEAYGGAGLDYWYNVVLAEELGYA
DCGGVPMAIAVHTDMATPALAEFGSDELRQRFLAPAIRGEMIAAVAISEPDAGSDVAAIRTRAVRDGDEYVINGHKMWIT
NGTQADFITLLARTSDEPGYKSMSLLIVPTNTPGFHVSKKLEKLGNHSSDTALLAFDDVRVPVANRIGDEGQGFVLQMQQ
FQKERLIGAVSAVSAMERIVEMTSHYCRERQTFGKPLIENQYIQFRLAELLTEIEALRQLNYHCTRLLLAGHDITKEVSM
AKLKAGRLAREVADTCLQFHGGMGYVEEYPMARYFRDARLLSIGGGADEIMLGIIAKYAGLSRKRG
>Mature_385_residues
SLYFNAEHELFRQTIRRFVEREINPFVEQWEHERAFPGHALFKKLGELDALGVSYPEAYGGAGLDYWYNVVLAEELGYAD
CGGVPMAIAVHTDMATPALAEFGSDELRQRFLAPAIRGEMIAAVAISEPDAGSDVAAIRTRAVRDGDEYVINGHKMWITN
GTQADFITLLARTSDEPGYKSMSLLIVPTNTPGFHVSKKLEKLGNHSSDTALLAFDDVRVPVANRIGDEGQGFVLQMQQF
QKERLIGAVSAVSAMERIVEMTSHYCRERQTFGKPLIENQYIQFRLAELLTEIEALRQLNYHCTRLLLAGHDITKEVSMA
KLKAGRLAREVADTCLQFHGGMGYVEEYPMARYFRDARLLSIGGGADEIMLGIIAKYAGLSRKRG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=376, Percent_Identity=35.9042553191489, Blast_Score=248, Evalue=5e-66,
Organism=Homo sapiens, GI226958412, Length=373, Percent_Identity=33.7801608579088, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI4557233, Length=370, Percent_Identity=36.4864864864865, Blast_Score=238, Evalue=9e-63,
Organism=Homo sapiens, GI226958414, Length=360, Percent_Identity=34.4444444444444, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI4557231, Length=380, Percent_Identity=35, Blast_Score=229, Evalue=2e-60,
Organism=Homo sapiens, GI187960098, Length=380, Percent_Identity=35, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=32.620320855615, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI7656849, Length=377, Percent_Identity=33.42175066313, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI21361497, Length=374, Percent_Identity=31.0160427807487, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI76496475, Length=337, Percent_Identity=30.2670623145401, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI4557235, Length=337, Percent_Identity=30.2670623145401, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI38505218, Length=373, Percent_Identity=28.1501340482574, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI211971008, Length=286, Percent_Identity=29.3706293706294, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI48976061, Length=286, Percent_Identity=29.3706293706294, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI4503943, Length=347, Percent_Identity=27.6657060518732, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI7669494, Length=347, Percent_Identity=27.6657060518732, Blast_Score=116, Evalue=3e-26,
Organism=Escherichia coli, GI87081958, Length=382, Percent_Identity=29.5811518324607, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786223, Length=373, Percent_Identity=26.0053619302949, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87082384, Length=311, Percent_Identity=25.4019292604502, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17551932, Length=376, Percent_Identity=47.0744680851064, Blast_Score=361, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17505929, Length=376, Percent_Identity=47.0744680851064, Blast_Score=355, Evalue=3e-98,
Organism=Caenorhabditis elegans, GI17570075, Length=380, Percent_Identity=34.4736842105263, Blast_Score=238, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI17538396, Length=379, Percent_Identity=33.245382585752, Blast_Score=235, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17508101, Length=363, Percent_Identity=32.5068870523416, Blast_Score=214, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI17506239, Length=372, Percent_Identity=31.7204301075269, Blast_Score=204, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI17534899, Length=372, Percent_Identity=33.0645161290323, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17533517, Length=364, Percent_Identity=31.8681318681319, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17569725, Length=363, Percent_Identity=30.3030303030303, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI71990804, Length=274, Percent_Identity=33.5766423357664, Blast_Score=167, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI71985184, Length=362, Percent_Identity=31.767955801105, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=31.4655172413793, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71985192, Length=287, Percent_Identity=32.0557491289199, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71982178, Length=276, Percent_Identity=27.1739130434783, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17534353, Length=344, Percent_Identity=27.906976744186, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17562446, Length=294, Percent_Identity=27.5510204081633, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=28.6307053941909, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI86563383, Length=304, Percent_Identity=27.6315789473684, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI86563381, Length=304, Percent_Identity=27.6315789473684, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17531913, Length=178, Percent_Identity=26.9662921348315, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356377, Length=368, Percent_Identity=34.2391304347826, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24646207, Length=369, Percent_Identity=34.6883468834688, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI21355753, Length=376, Percent_Identity=33.2446808510638, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24666513, Length=374, Percent_Identity=31.8181818181818, Blast_Score=214, Evalue=8e-56,
Organism=Drosophila melanogaster, GI24660351, Length=369, Percent_Identity=34.4173441734417, Blast_Score=211, Evalue=7e-55,
Organism=Drosophila melanogaster, GI281363737, Length=347, Percent_Identity=30.835734870317, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI19920834, Length=349, Percent_Identity=29.2263610315186, Blast_Score=132, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43031; Mature: 42900

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLYFNAEHELFRQTIRRFVEREINPFVEQWEHERAFPGHALFKKLGELDALGVSYPEAY
CCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHCCCCCCHHH
GGAGLDYWYNVVLAEELGYADCGGVPMAIAVHTDMATPALAEFGSDELRQRFLAPAIRGE
CCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHCC
MIAAVAISEPDAGSDVAAIRTRAVRDGDEYVINGHKMWITNGTQADFITLLARTSDEPGY
EEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEECEEEEEECCCCHHHHHHHHHCCCCCCC
KSMSLLIVPTNTPGFHVSKKLEKLGNHSSDTALLAFDDVRVPVANRIGDEGQGFVLQMQQ
CCEEEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHCCCCCCCHHHHHHH
FQKERLIGAVSAVSAMERIVEMTSHYCRERQTFGKPLIENQYIQFRLAELLTEIEALRQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
NYHCTRLLLAGHDITKEVSMAKLKAGRLAREVADTCLQFHGGMGYVEEYPMARYFRDARL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHCCCEE
LSIGGGADEIMLGIIAKYAGLSRKRG
EEECCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SLYFNAEHELFRQTIRRFVEREINPFVEQWEHERAFPGHALFKKLGELDALGVSYPEAY
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHCCCCCCHHH
GGAGLDYWYNVVLAEELGYADCGGVPMAIAVHTDMATPALAEFGSDELRQRFLAPAIRGE
CCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHCC
MIAAVAISEPDAGSDVAAIRTRAVRDGDEYVINGHKMWITNGTQADFITLLARTSDEPGY
EEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEECEEEEEECCCCHHHHHHHHHCCCCCCC
KSMSLLIVPTNTPGFHVSKKLEKLGNHSSDTALLAFDDVRVPVANRIGDEGQGFVLQMQQ
CCEEEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHCCCCCCCHHHHHHH
FQKERLIGAVSAVSAMERIVEMTSHYCRERQTFGKPLIENQYIQFRLAELLTEIEALRQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
NYHCTRLLLAGHDITKEVSMAKLKAGRLAREVADTCLQFHGGMGYVEEYPMARYFRDARL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHCCCEE
LSIGGGADEIMLGIIAKYAGLSRKRG
EEECCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]