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The map label for this gene is xseA [H]

Identifier: 159901240

GI number: 159901240

Start: 6038556

End: 6039734

Strand: Direct

Name: xseA [H]

Synonym: Haur_4728

Alternate gene names: 159901240

Gene position: 6038556-6039734 (Clockwise)

Preceding gene: 159901239

Following gene: 159901241

Centisome position: 95.15

GC content: 50.64

Gene sequence:

>1179_bases
ATGGAACAACTTTCAGTCAGCGAGTTATGTGGCTATATCAATGCAGTGCTCACTAGCGACCCCGTGGTGAGTGATGTTTG
GGTTTATGGCGAGGTTTCTAACTGCAAACGCCATTCATCAGGCCATTGGTATTTGACCCTCAAAGAGGCCGATGCCCGCA
TTGATGCGGTGATTTGGCGTTCCACAGCCTTGCGTTTGAGCTACTTACCTCAAGATGGCATGGCGATTTTAGGTCATGGC
AAAGTTGAACTGTATAATGGACGCTTGCAAATTTATCTTGATTTTATTACTCCTGCTGGCGAAGGCCTGTTGCAAGCCCA
ATATGAACGGCTCAAAGCCCAATTAGAAGCCGAAGGTTTGACCGAACGCAAACGGCCATTGCCGCTATTTCCCCAACGCA
TCGGCATTGTTACTTCGCCAACTGGAGCGGCCTTGCAGGATATGTTGAATGTGCTGCGCCGCCGTTTTCCTTTGGCCGAA
GTGATTATCGCGCCAGCCCTTGTGCAGGGCGAAGATGCCGCGCCTTCGATTGTTGAGGCCTTGTATGAGCTTTTCGATTT
CGAGCCAGATGTGATTATTGTGGCCCGTGGCGGTGGCTCAATTGAAGATCTTTGGGCGTTCAACGAGGAGATTGTGGCAC
GGGCAGTTTTTGCCTCGCCAGTACCAGTCGTCACCGGAGTTGGCCACGAAACCGATACCACAATTGTCGATTTTGTTGCC
GATTTGCGTGCGCCAACGCCTTCGGCTGCTGCCGAGTTGGTCACACCTGATTTGGTCACATTGCGCGATGAATTGATCAG
CCACGTTGGACTGTTGCATGGCTTGTTTCAAGGGCGTTTGCAATTGCTGCGCAGCGAATTAGGCCAACAGCAACAACAAC
TTTTACGTCACAACCCGCAAATGCGGCTACATCAAGCGCATGAGCAGGTCAATGCCCAACAACAGCAGTTGCAGCGAACG
ATCCAGCGCATGCTCGAAATGGCTCGCTTAAAAGTTCAAGTGGCCGAACGCAGTTTAGTTGCACTCAATCCTGAACGAAC
CTTGGCGCGAGGCTATGCCGTTGTATTACATAACGATCGTTCCCTGACCAACACCAGCCACGTAGCAGTTGGCGATACAA
TTAATATTCAATTGCATCAAGGCCAGCTTCAAGCCACAATTACCGAGCTACGAGATTAA

Upstream 100 bases:

>100_bases
GGGTGAGGGAACACATTCAATCAGCTAAATAATTGTCGATTGTTTTTTTGGTTAAACCCTCGTACAATTGTGCTACTATC
CTCAGCAAGCAGGCCAATCT

Downstream 100 bases:

>100_bases
GCGATGCTACTCGCTAGTCTAACCATTAAACCACCAGCTGCTCATGATGCTGAGCAATTTCCTCTGAATGTGCCAGCCAT
CCAAGCCTTGGTTGGCCAAA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MEQLSVSELCGYINAVLTSDPVVSDVWVYGEVSNCKRHSSGHWYLTLKEADARIDAVIWRSTALRLSYLPQDGMAILGHG
KVELYNGRLQIYLDFITPAGEGLLQAQYERLKAQLEAEGLTERKRPLPLFPQRIGIVTSPTGAALQDMLNVLRRRFPLAE
VIIAPALVQGEDAAPSIVEALYELFDFEPDVIIVARGGGSIEDLWAFNEEIVARAVFASPVPVVTGVGHETDTTIVDFVA
DLRAPTPSAAAELVTPDLVTLRDELISHVGLLHGLFQGRLQLLRSELGQQQQQLLRHNPQMRLHQAHEQVNAQQQQLQRT
IQRMLEMARLKVQVAERSLVALNPERTLARGYAVVLHNDRSLTNTSHVAVGDTINIQLHQGQLQATITELRD

Sequences:

>Translated_392_residues
MEQLSVSELCGYINAVLTSDPVVSDVWVYGEVSNCKRHSSGHWYLTLKEADARIDAVIWRSTALRLSYLPQDGMAILGHG
KVELYNGRLQIYLDFITPAGEGLLQAQYERLKAQLEAEGLTERKRPLPLFPQRIGIVTSPTGAALQDMLNVLRRRFPLAE
VIIAPALVQGEDAAPSIVEALYELFDFEPDVIIVARGGGSIEDLWAFNEEIVARAVFASPVPVVTGVGHETDTTIVDFVA
DLRAPTPSAAAELVTPDLVTLRDELISHVGLLHGLFQGRLQLLRSELGQQQQQLLRHNPQMRLHQAHEQVNAQQQQLQRT
IQRMLEMARLKVQVAERSLVALNPERTLARGYAVVLHNDRSLTNTSHVAVGDTINIQLHQGQLQATITELRD
>Mature_392_residues
MEQLSVSELCGYINAVLTSDPVVSDVWVYGEVSNCKRHSSGHWYLTLKEADARIDAVIWRSTALRLSYLPQDGMAILGHG
KVELYNGRLQIYLDFITPAGEGLLQAQYERLKAQLEAEGLTERKRPLPLFPQRIGIVTSPTGAALQDMLNVLRRRFPLAE
VIIAPALVQGEDAAPSIVEALYELFDFEPDVIIVARGGGSIEDLWAFNEEIVARAVFASPVPVVTGVGHETDTTIVDFVA
DLRAPTPSAAAELVTPDLVTLRDELISHVGLLHGLFQGRLQLLRSELGQQQQQLLRHNPQMRLHQAHEQVNAQQQQLQRT
IQRMLEMARLKVQVAERSLVALNPERTLARGYAVVLHNDRSLTNTSHVAVGDTINIQLHQGQLQATITELRD

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=442, Percent_Identity=38.6877828054299, Blast_Score=270, Evalue=2e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 43535; Mature: 43535

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQLSVSELCGYINAVLTSDPVVSDVWVYGEVSNCKRHSSGHWYLTLKEADARIDAVIWR
CCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHCCCCCCEEEEEECCCCCCHHHEEH
STALRLSYLPQDGMAILGHGKVELYNGRLQIYLDFITPAGEGLLQAQYERLKAQLEAEGL
HHHEEEEECCCCCCEEEECCEEEEECCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCC
TERKRPLPLFPQRIGIVTSPTGAALQDMLNVLRRRFPLAEVIIAPALVQGEDAAPSIVEA
CCCCCCCCCCHHHCCEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHH
LYELFDFEPDVIIVARGGGSIEDLWAFNEEIVARAVFASPVPVVTGVGHETDTTIVDFVA
HHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHH
DLRAPTPSAAAELVTPDLVTLRDELISHVGLLHGLFQGRLQLLRSELGQQQQQLLRHNPQ
HHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
MRLHQAHEQVNAQQQQLQRTIQRMLEMARLKVQVAERSLVALNPERTLARGYAVVLHNDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCCEEEEEECCC
SLTNTSHVAVGDTINIQLHQGQLQATITELRD
CCCCCCEEEECCEEEEEEECCHHHHHHHHHCC
>Mature Secondary Structure
MEQLSVSELCGYINAVLTSDPVVSDVWVYGEVSNCKRHSSGHWYLTLKEADARIDAVIWR
CCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHCCCCCCEEEEEECCCCCCHHHEEH
STALRLSYLPQDGMAILGHGKVELYNGRLQIYLDFITPAGEGLLQAQYERLKAQLEAEGL
HHHEEEEECCCCCCEEEECCEEEEECCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCC
TERKRPLPLFPQRIGIVTSPTGAALQDMLNVLRRRFPLAEVIIAPALVQGEDAAPSIVEA
CCCCCCCCCCHHHCCEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHH
LYELFDFEPDVIIVARGGGSIEDLWAFNEEIVARAVFASPVPVVTGVGHETDTTIVDFVA
HHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHH
DLRAPTPSAAAELVTPDLVTLRDELISHVGLLHGLFQGRLQLLRSELGQQQQQLLRHNPQ
HHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
MRLHQAHEQVNAQQQQLQRTIQRMLEMARLKVQVAERSLVALNPERTLARGYAVVLHNDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCCEEEEEECCC
SLTNTSHVAVGDTINIQLHQGQLQATITELRD
CCCCCCEEEECCEEEEEEECCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA