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The map label for this gene is ubiB [C]

Identifier: 159901233

GI number: 159901233

Start: 6030293

End: 6031981

Strand: Reverse

Name: ubiB [C]

Synonym: Haur_4721

Alternate gene names: 159901233

Gene position: 6031981-6030293 (Counterclockwise)

Preceding gene: 159901234

Following gene: 159901232

Centisome position: 95.04

GC content: 49.85

Gene sequence:

>1689_bases
ATGAGTAAACCTGAGTTGGTGTCGTTGCCAAATGTTCCACGCCGCCGTCGTTTCTTTCGCGTCGCGTGGTTTTTTGTGCG
CTTAGTTGCCCATATTATCGTCTGGGATTTGTTGCTCGGACGGCAGTTTTGGTTTCGCTGGTACGCGGATCGCACGCGGA
TCGAGCGCTATCGGCGTTTTTCGCGGCGCTTCCGCGATTTGGCGATCGATCTTGGCGGCGTGATGATTAAGCTTGGGCAA
TTTGCTTCAACTCGCGTCGATGTGTTGCCGCCAGCCGTGGTTGAAGATTTGATCGGCTTGCAAGATGAAGTTTCGCCCGT
ACCATTTCGCTTGATTCAAGCCACAATCGAACACGAATTAGGCCAACCACTCGATCATATTTTTAAAACTTTTGAGCGTG
AACCAATCGCTGCTGCGTCGTTTGGCCAAGTGCATTTCGCCACGCTGCACAACGATCAGCCGATTGCCATCAAAATTCAA
CGCCCACAAATTGAGCAATTTGTTGAAATCGATATTGCTGCACTGCGCTGGGTTGCTAGTTGGATGCAATATTATGGCCC
AATTCGCCGTCGCACCGATTTACCAGCGCTGATCGAAGAGTTTTCGCGAATTACTCTGCGCGAACTCGATTACCTAAGCG
AAGCTGATCACGCCGAGCGCTTTCAGCGTAATTTTGCTGGCAACGATCATATTTATGTGCCAAAAATTCAGCGCGATTAT
TCAACTGAACGAATTTTGGTGATGGAGCGAATCGAGGGCATTAAAATTTCGGAATATGCGGCGCTCGATGCAGCTGGAAT
AGATCGGCTGGATTTGGCCGAAAAGCTTTATTTGGCCTATTTGCAACAATGCTTTACCGATGGCTTTTTTCATGCCGACC
CACACCCAGGCAATTTGTTTGTGCGGCCTGTCGGCGAGCGCTTGGCGAATGGCAAACAACCCTTTGTAATCACCTTCCTC
GATTTTGGCATGGTCGATTCAATTCCCCAAAGCGTGATGGATGGCCTCGCCACGATTGCAGCTGGCGTGGTAATGCGCGA
ACCACAACGTATGATCGATGGCGCACGCTCGATTGGCGTGGTCATGCCCAATGCCAATGATCAACAATTACGCCAAGCCT
TGGAAATTTGGTTTTCCTATACCTATGGCCGCACAATTCGCGAGTTGCAACAAATCGATGTTGAGGGTTTTGTCGGCGGA
TTAAGCGAATTGCTCTATGATTTGCCGTTTCAGTTGCCTCAATCATTACTCTTTTTGGGACGCACGGTAGGGATTATCGG
TGGCGTGGCGGCTGGTTTAGCGCCCGATTTTGATATTTTCAGCGTGACTAAACCCTTTGCCTTACGCTTTATTCGTGAGC
AAACCAGTGGCCGCGATCTGCGCGAACGGGTAATTAACGAAGGCCGCGAATTAATTACCGACCTCAGCCAAATTCCGCGC
CATGCCAAACAATTTTACGTCAAGGCTGCTCAAGGCGATTTGCAAGTGCGCACCGAAATTGTCAAACTAGAGCGCACCAC
CAAACGAATCGAGCGGGCATTGAGCCGTCTTACCGCAGGGATTGCGGCAAGCGCCTTGATCATCAGCGCGAGCATTCTCC
AAGCCCAACAGATTTATAGCCCTTGGATGTGGTGGTTGGCTGGTGGTTTGTTGATTTGGTCATTGTTGCCACGCTTCAAT
CAAAATTAA

Upstream 100 bases:

>100_bases
GAGGGGCTGGGGGTGAGGGCTTGTTACAATGACAGCTAGTCCCTGACCCCTGACCCCTCATCGCTAACGCGGGCAGCAAT
CGCCTGCTATAATACCGAGT

Downstream 100 bases:

>100_bases
TCGAGCGCCTTGCAAGGATCGGTTTTCGCTGCGAACCATCCCACCATGACGATTGGAACACCCCTCCCCCACTGCGGCAT
TTAAGGGCGGACAGGGACGC

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MSKPELVSLPNVPRRRRFFRVAWFFVRLVAHIIVWDLLLGRQFWFRWYADRTRIERYRRFSRRFRDLAIDLGGVMIKLGQ
FASTRVDVLPPAVVEDLIGLQDEVSPVPFRLIQATIEHELGQPLDHIFKTFEREPIAAASFGQVHFATLHNDQPIAIKIQ
RPQIEQFVEIDIAALRWVASWMQYYGPIRRRTDLPALIEEFSRITLRELDYLSEADHAERFQRNFAGNDHIYVPKIQRDY
STERILVMERIEGIKISEYAALDAAGIDRLDLAEKLYLAYLQQCFTDGFFHADPHPGNLFVRPVGERLANGKQPFVITFL
DFGMVDSIPQSVMDGLATIAAGVVMREPQRMIDGARSIGVVMPNANDQQLRQALEIWFSYTYGRTIRELQQIDVEGFVGG
LSELLYDLPFQLPQSLLFLGRTVGIIGGVAAGLAPDFDIFSVTKPFALRFIREQTSGRDLRERVINEGRELITDLSQIPR
HAKQFYVKAAQGDLQVRTEIVKLERTTKRIERALSRLTAGIAASALIISASILQAQQIYSPWMWWLAGGLLIWSLLPRFN
QN

Sequences:

>Translated_562_residues
MSKPELVSLPNVPRRRRFFRVAWFFVRLVAHIIVWDLLLGRQFWFRWYADRTRIERYRRFSRRFRDLAIDLGGVMIKLGQ
FASTRVDVLPPAVVEDLIGLQDEVSPVPFRLIQATIEHELGQPLDHIFKTFEREPIAAASFGQVHFATLHNDQPIAIKIQ
RPQIEQFVEIDIAALRWVASWMQYYGPIRRRTDLPALIEEFSRITLRELDYLSEADHAERFQRNFAGNDHIYVPKIQRDY
STERILVMERIEGIKISEYAALDAAGIDRLDLAEKLYLAYLQQCFTDGFFHADPHPGNLFVRPVGERLANGKQPFVITFL
DFGMVDSIPQSVMDGLATIAAGVVMREPQRMIDGARSIGVVMPNANDQQLRQALEIWFSYTYGRTIRELQQIDVEGFVGG
LSELLYDLPFQLPQSLLFLGRTVGIIGGVAAGLAPDFDIFSVTKPFALRFIREQTSGRDLRERVINEGRELITDLSQIPR
HAKQFYVKAAQGDLQVRTEIVKLERTTKRIERALSRLTAGIAASALIISASILQAQQIYSPWMWWLAGGLLIWSLLPRFN
QN
>Mature_561_residues
SKPELVSLPNVPRRRRFFRVAWFFVRLVAHIIVWDLLLGRQFWFRWYADRTRIERYRRFSRRFRDLAIDLGGVMIKLGQF
ASTRVDVLPPAVVEDLIGLQDEVSPVPFRLIQATIEHELGQPLDHIFKTFEREPIAAASFGQVHFATLHNDQPIAIKIQR
PQIEQFVEIDIAALRWVASWMQYYGPIRRRTDLPALIEEFSRITLRELDYLSEADHAERFQRNFAGNDHIYVPKIQRDYS
TERILVMERIEGIKISEYAALDAAGIDRLDLAEKLYLAYLQQCFTDGFFHADPHPGNLFVRPVGERLANGKQPFVITFLD
FGMVDSIPQSVMDGLATIAAGVVMREPQRMIDGARSIGVVMPNANDQQLRQALEIWFSYTYGRTIRELQQIDVEGFVGGL
SELLYDLPFQLPQSLLFLGRTVGIIGGVAAGLAPDFDIFSVTKPFALRFIREQTSGRDLRERVINEGRELITDLSQIPRH
AKQFYVKAAQGDLQVRTEIVKLERTTKRIERALSRLTAGIAASALIISASILQAQQIYSPWMWWLAGGLLIWSLLPRFNQ
N

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393593, Length=294, Percent_Identity=30.2721088435374, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI40254938, Length=307, Percent_Identity=26.7100977198697, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI217035081, Length=241, Percent_Identity=26.9709543568465, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI34147522, Length=269, Percent_Identity=26.0223048327138, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI32261307, Length=344, Percent_Identity=23.546511627907, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI27363457, Length=262, Percent_Identity=27.4809160305344, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI217416386, Length=218, Percent_Identity=29.8165137614679, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI2367309, Length=512, Percent_Identity=29.296875, Blast_Score=196, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17559152, Length=277, Percent_Identity=28.8808664259928, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32565180, Length=288, Percent_Identity=25.6944444444444, Blast_Score=89, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6323282, Length=263, Percent_Identity=30.0380228136882, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6325148, Length=258, Percent_Identity=26.3565891472868, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6321319, Length=255, Percent_Identity=29.4117647058824, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24662575, Length=304, Percent_Identity=28.2894736842105, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI22024280, Length=288, Percent_Identity=27.7777777777778, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI18859849, Length=270, Percent_Identity=27.4074074074074, Blast_Score=89, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 64526; Mature: 64395

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPELVSLPNVPRRRRFFRVAWFFVRLVAHIIVWDLLLGRQFWFRWYADRTRIERYRRF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRRFRDLAIDLGGVMIKLGQFASTRVDVLPPAVVEDLIGLQDEVSPVPFRLIQATIEHEL
HHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
GQPLDHIFKTFEREPIAAASFGQVHFATLHNDQPIAIKIQRPQIEQFVEIDIAALRWVAS
CCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
WMQYYGPIRRRTDLPALIEEFSRITLRELDYLSEADHAERFQRNFAGNDHIYVPKIQRDY
HHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEECCHHCCC
STERILVMERIEGIKISEYAALDAAGIDRLDLAEKLYLAYLQQCFTDGFFHADPHPGNLF
CCHHHHHHHHHCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
VRPVGERLANGKQPFVITFLDFGMVDSIPQSVMDGLATIAAGVVMREPQRMIDGARSIGV
EEEHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHCEE
VMPNANDQQLRQALEIWFSYTYGRTIRELQQIDVEGFVGGLSELLYDLPFQLPQSLLFLG
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RTVGIIGGVAAGLAPDFDIFSVTKPFALRFIREQTSGRDLRERVINEGRELITDLSQIPR
HHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
HAKQFYVKAAQGDLQVRTEIVKLERTTKRIERALSRLTAGIAASALIISASILQAQQIYS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PWMWWLAGGLLIWSLLPRFNQN
HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKPELVSLPNVPRRRRFFRVAWFFVRLVAHIIVWDLLLGRQFWFRWYADRTRIERYRRF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRRFRDLAIDLGGVMIKLGQFASTRVDVLPPAVVEDLIGLQDEVSPVPFRLIQATIEHEL
HHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
GQPLDHIFKTFEREPIAAASFGQVHFATLHNDQPIAIKIQRPQIEQFVEIDIAALRWVAS
CCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
WMQYYGPIRRRTDLPALIEEFSRITLRELDYLSEADHAERFQRNFAGNDHIYVPKIQRDY
HHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEECCHHCCC
STERILVMERIEGIKISEYAALDAAGIDRLDLAEKLYLAYLQQCFTDGFFHADPHPGNLF
CCHHHHHHHHHCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
VRPVGERLANGKQPFVITFLDFGMVDSIPQSVMDGLATIAAGVVMREPQRMIDGARSIGV
EEEHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHCEE
VMPNANDQQLRQALEIWFSYTYGRTIRELQQIDVEGFVGGLSELLYDLPFQLPQSLLFLG
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RTVGIIGGVAAGLAPDFDIFSVTKPFALRFIREQTSGRDLRERVINEGRELITDLSQIPR
HHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
HAKQFYVKAAQGDLQVRTEIVKLERTTKRIERALSRLTAGIAASALIISASILQAQQIYS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PWMWWLAGGLLIWSLLPRFNQN
HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]