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The map label for this gene is sigK [H]

Identifier: 159901162

GI number: 159901162

Start: 5941264

End: 5941839

Strand: Direct

Name: sigK [H]

Synonym: Haur_4650

Alternate gene names: 159901162

Gene position: 5941264-5941839 (Clockwise)

Preceding gene: 159901152

Following gene: 159901163

Centisome position: 93.61

GC content: 51.56

Gene sequence:

>576_bases
ATGCCTGGTGATCCGCCAGGTGATAATGTGTTAATTCGGCGGATTGCCCAGGGCGATGAGCAGGCGCTATCGCAACTTTA
CGATCGGTATGCTGCAACAGTGATGGGGATTGCCTTGAAAATCGTGCGTCAACGCGAGATTGCCGAGGAAATTACCCAAG
AGGCTTTTTGGCGAGTATGGCAACGGGCAAGCACATTTGATAATAGCCGTGGTAATTGTGCCCCTTGGCTTTTTGGCATT
GCTCGCAACTTGAGCATCGACGAACTGCGCCGTCGTGCGGCTCGCCCTCAAGCTGCCTATGAAGACCCTGAAAGACCATT
GCTTGAGGCGATTGCCGATGAAGCCAATGTGGAAGAAGTTGTCTGGTTGGGTGAACAACGCTCAGTTGTGCGCTCAGCAA
TGCAGGCGCTTTCTGCCGAACAACGTGAAGCGTTGGAACTAGCCTATTTTAGTGGGCTGACTCAACGTGAAATTGCCGAT
AAATTAGGCAATCCCTTGGGCACGATCAAAACGCGTGTGCGGCTTGGTCTCTTGAAACTGCGTGATCTTTTGGGTACACA
ACAGTGGAACGAATGA

Upstream 100 bases:

>100_bases
GTTTGCCCAAATTGTTCAACAGGTTCAGCTATGGTGGGCTGCTTCAACCATCCGTTCGGATGCTTCGGACGTAGTACCAA
TTAACGATAATCAGCGCCCA

Downstream 100 bases:

>100_bases
TGGATGCACAATTAGAAGAACTCTTGATTGGTTATGCACTTGGCATTTTGAGTCTCGATGAGCAACAATCGGTCGAAATT
CAAATCGCCAATAATCCACT

Product: ECF subfamily RNA polymerase sigma-24 factor

Products: NA

Alternate protein names: Sigma-K factor [H]

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MPGDPPGDNVLIRRIAQGDEQALSQLYDRYAATVMGIALKIVRQREIAEEITQEAFWRVWQRASTFDNSRGNCAPWLFGI
ARNLSIDELRRRAARPQAAYEDPERPLLEAIADEANVEEVVWLGEQRSVVRSAMQALSAEQREALELAYFSGLTQREIAD
KLGNPLGTIKTRVRLGLLKLRDLLGTQQWNE

Sequences:

>Translated_191_residues
MPGDPPGDNVLIRRIAQGDEQALSQLYDRYAATVMGIALKIVRQREIAEEITQEAFWRVWQRASTFDNSRGNCAPWLFGI
ARNLSIDELRRRAARPQAAYEDPERPLLEAIADEANVEEVVWLGEQRSVVRSAMQALSAEQREALELAYFSGLTQREIAD
KLGNPLGTIKTRVRLGLLKLRDLLGTQQWNE
>Mature_190_residues
PGDPPGDNVLIRRIAQGDEQALSQLYDRYAATVMGIALKIVRQREIAEEITQEAFWRVWQRASTFDNSRGNCAPWLFGIA
RNLSIDELRRRAARPQAAYEDPERPLLEAIADEANVEEVVWLGEQRSVVRSAMQALSAEQREALELAYFSGLTQREIADK
LGNPLGTIKTRVRLGLLKLRDLLGTQQWNE

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=172, Percent_Identity=29.0697674418605, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR007627
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 21646; Mature: 21515

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGDPPGDNVLIRRIAQGDEQALSQLYDRYAATVMGIALKIVRQREIAEEITQEAFWRVW
CCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRASTFDNSRGNCAPWLFGIARNLSIDELRRRAARPQAAYEDPERPLLEAIADEANVEEV
HHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHH
VWLGEQRSVVRSAMQALSAEQREALELAYFSGLTQREIADKLGNPLGTIKTRVRLGLLKL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
RDLLGTQQWNE
HHHHHCCCCCC
>Mature Secondary Structure 
PGDPPGDNVLIRRIAQGDEQALSQLYDRYAATVMGIALKIVRQREIAEEITQEAFWRVW
CCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRASTFDNSRGNCAPWLFGIARNLSIDELRRRAARPQAAYEDPERPLLEAIADEANVEEV
HHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHH
VWLGEQRSVVRSAMQALSAEQREALELAYFSGLTQREIADKLGNPLGTIKTRVRLGLLKL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
RDLLGTQQWNE
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]