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The map label for this gene is yfbK [C]

Identifier: 159900723

GI number: 159900723

Start: 5363894

End: 5365159

Strand: Reverse

Name: yfbK [C]

Synonym: Haur_4210

Alternate gene names: 159900723

Gene position: 5365159-5363894 (Counterclockwise)

Preceding gene: 159900724

Following gene: 159900721

Centisome position: 84.54

GC content: 51.5

Gene sequence:

>1266_bases
ATGGCAGGTGAAGTTCAATTAACTGGTACGTTGGCTCGACCGGCGTTGCCAGCCTTGCAAACCCAGCAGGTTGTTTATTT
ACTGCTGGATATTACGGCAACACCAGCGGTTGCTCACGTTCAAATGCCAGTTAATGTGAGCTTCGTGCTCGATCATAGTG
GCTCGATGAAGGGCGACAAAATGCGCTGTGTGCGCGAAGCTACCCAACGCGCTCTGGGCTTGATGGGGCCGCAAGATATT
GTTTCGGTGGTGATTTTCGACCATCGCCGCGAAACGATTATCAGTGCTCAGCCTGTTCGCAACGTTGCTGCCTTACAAGC
TGAAGTTGGTAAAATCAAAGATGCAGGTGGTACAAAAATCGCACCTGCGCTCGAAGCTGCCTTGAATGAAATTCGCCGTA
GCCAAAATGCCAATACGATCAGCCGCATTATTTTGCTGACCGACGGTCAAACCGAGGGCGAACGCGATTGTTTGCGCTTG
GCCGAGGAAATTGGCAAAGCTAGTGTGCCATTGACGGCACTGGGCGTTGGCGACGATTGGAACGAAGATCTGTTGATCGA
AATGGCGAATCGCTCAGGTGGCGTTGCCGAATATTTCAGCAATCCCAACGATATCGCCTCGTTCTTCCAAGGTGCGGTGC
AGCAAGCCCAATCGGCGGTGGTGCAAAACTCAGCCTTGACCTTGCGCTTTGTGCAGGGAGTTGAGCCACGCGCCCTTTGG
CAAGTAACCCCATTAATTCAACAATTGCCCTATCGGCCAATTAGCGATCGGGCGGTTGGCGTGAGCCTCGGCGATATTTC
CAAAGACGAACATCGGATGGTGCTAATCGAAATGCTGGTTGATCCCAAGCAGGCGGGCCAATATCGGCTGGGCCAAATCG
AGGTCAACTACGATATTCCTCAAATGCAGGTAGTTGGCGAAAAAGCTCGCTACGATGTCATGTTGAATTTTGTGGCTGAT
CCGGCTCAGGCAACCGGAGTTGTGCCCCAAGTGATGAATATTGTTGAAAAGGTCAGCGCCCACAAGCTGCAAACTCGGGC
CTTAGAAGATTTGGCCGAGGGCAATATTGGTGCAGCGACCCAAAAGCTTCAAGGTGCTGTGACCCGCTTGCTCAACCAAG
GCGAAACCGAGCTAGCCCAAACCATGCAACAAGAGATCGAAAATCTACAAACCAATGGGCAAATGACCTCAGCTGGTCAA
AAAACCATCAAATTTGGTACCCGCAAAACCGTGCGGCTCAGCGATTTGGATCTACCAAAAAGTTAG

Upstream 100 bases:

>100_bases
CAGGATTTCTCCCCTCTCCCGCCGCCGTGGGCGAGGGGTCGGGGTGAGGGAACGAGAACACTCAATCTATGTTCTATGTT
CTCTATAAAGGAGATCACCA

Downstream 100 bases:

>100_bases
TAACCGCTAAGAACGCCAAGAGCACGAAAAATCAATGTCAAAGATTTCTTCGTGCTCTTGGTGTTCTTTGTGGTTTCAGC
TACGCCATAGCTTTGCGTCG

Product: von Willebrand factor type A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MAGEVQLTGTLARPALPALQTQQVVYLLLDITATPAVAHVQMPVNVSFVLDHSGSMKGDKMRCVREATQRALGLMGPQDI
VSVVIFDHRRETIISAQPVRNVAALQAEVGKIKDAGGTKIAPALEAALNEIRRSQNANTISRIILLTDGQTEGERDCLRL
AEEIGKASVPLTALGVGDDWNEDLLIEMANRSGGVAEYFSNPNDIASFFQGAVQQAQSAVVQNSALTLRFVQGVEPRALW
QVTPLIQQLPYRPISDRAVGVSLGDISKDEHRMVLIEMLVDPKQAGQYRLGQIEVNYDIPQMQVVGEKARYDVMLNFVAD
PAQATGVVPQVMNIVEKVSAHKLQTRALEDLAEGNIGAATQKLQGAVTRLLNQGETELAQTMQQEIENLQTNGQMTSAGQ
KTIKFGTRKTVRLSDLDLPKS

Sequences:

>Translated_421_residues
MAGEVQLTGTLARPALPALQTQQVVYLLLDITATPAVAHVQMPVNVSFVLDHSGSMKGDKMRCVREATQRALGLMGPQDI
VSVVIFDHRRETIISAQPVRNVAALQAEVGKIKDAGGTKIAPALEAALNEIRRSQNANTISRIILLTDGQTEGERDCLRL
AEEIGKASVPLTALGVGDDWNEDLLIEMANRSGGVAEYFSNPNDIASFFQGAVQQAQSAVVQNSALTLRFVQGVEPRALW
QVTPLIQQLPYRPISDRAVGVSLGDISKDEHRMVLIEMLVDPKQAGQYRLGQIEVNYDIPQMQVVGEKARYDVMLNFVAD
PAQATGVVPQVMNIVEKVSAHKLQTRALEDLAEGNIGAATQKLQGAVTRLLNQGETELAQTMQQEIENLQTNGQMTSAGQ
KTIKFGTRKTVRLSDLDLPKS
>Mature_420_residues
AGEVQLTGTLARPALPALQTQQVVYLLLDITATPAVAHVQMPVNVSFVLDHSGSMKGDKMRCVREATQRALGLMGPQDIV
SVVIFDHRRETIISAQPVRNVAALQAEVGKIKDAGGTKIAPALEAALNEIRRSQNANTISRIILLTDGQTEGERDCLRLA
EEIGKASVPLTALGVGDDWNEDLLIEMANRSGGVAEYFSNPNDIASFFQGAVQQAQSAVVQNSALTLRFVQGVEPRALWQ
VTPLIQQLPYRPISDRAVGVSLGDISKDEHRMVLIEMLVDPKQAGQYRLGQIEVNYDIPQMQVVGEKARYDVMLNFVADP
AQATGVVPQVMNIVEKVSAHKLQTRALEDLAEGNIGAATQKLQGAVTRLLNQGETELAQTMQQEIENLQTNGQMTSAGQK
TIKFGTRKTVRLSDLDLPKS

Specific function: Unknown

COG id: COG2304

COG function: function code R; Uncharacterized protein containing a von Willebrand factor type A (vWA) domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

Organism=Homo sapiens, GI70778918, Length=195, Percent_Identity=30.2564102564103, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI262050538, Length=202, Percent_Identity=29.7029702970297, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI31542984, Length=202, Percent_Identity=29.7029702970297, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI133925809, Length=193, Percent_Identity=27.979274611399, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002035 [H]

Pfam domain/function: PF00092 VWA [H]

EC number: NA

Molecular weight: Translated: 45732; Mature: 45601

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGEVQLTGTLARPALPALQTQQVVYLLLDITATPAVAHVQMPVNVSFVLDHSGSMKGDK
CCCCEEEEECCCCCCCCCHHHHHHHHEEEECCCCCCEEEEEECCEEEEEEECCCCCCCHH
MRCVREATQRALGLMGPQDIVSVVIFDHRRETIISAQPVRNVAALQAEVGKIKDAGGTKI
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCH
APALEAALNEIRRSQNANTISRIILLTDGQTEGERDCLRLAEEIGKASVPLTALGVGDDW
HHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCC
NEDLLIEMANRSGGVAEYFSNPNDIASFFQGAVQQAQSAVVQNSALTLRFVQGVEPRALW
CCCCEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
QVTPLIQQLPYRPISDRAVGVSLGDISKDEHRMVLIEMLVDPKQAGQYRLGQIEVNYDIP
HHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHEEEEHHHHCHHHCCCEEEEEEEEECCCC
QMQVVGEKARYDVMLNFVADPAQATGVVPQVMNIVEKVSAHKLQTRALEDLAEGNIGAAT
CHHHHCCHHHHEEEEEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
QKLQGAVTRLLNQGETELAQTMQQEIENLQTNGQMTSAGQKTIKFGTRKTVRLSDLDLPK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCEEEEECCCCCC
S
C
>Mature Secondary Structure 
AGEVQLTGTLARPALPALQTQQVVYLLLDITATPAVAHVQMPVNVSFVLDHSGSMKGDK
CCCEEEEECCCCCCCCCHHHHHHHHEEEECCCCCCEEEEEECCEEEEEEECCCCCCCHH
MRCVREATQRALGLMGPQDIVSVVIFDHRRETIISAQPVRNVAALQAEVGKIKDAGGTKI
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCH
APALEAALNEIRRSQNANTISRIILLTDGQTEGERDCLRLAEEIGKASVPLTALGVGDDW
HHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCC
NEDLLIEMANRSGGVAEYFSNPNDIASFFQGAVQQAQSAVVQNSALTLRFVQGVEPRALW
CCCCEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
QVTPLIQQLPYRPISDRAVGVSLGDISKDEHRMVLIEMLVDPKQAGQYRLGQIEVNYDIP
HHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHEEEEHHHHCHHHCCCEEEEEEEEECCCC
QMQVVGEKARYDVMLNFVADPAQATGVVPQVMNIVEKVSAHKLQTRALEDLAEGNIGAAT
CHHHHCCHHHHEEEEEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
QKLQGAVTRLLNQGETELAQTMQQEIENLQTNGQMTSAGQKTIKFGTRKTVRLSDLDLPK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCEEEEECCCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]