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The map label for this gene is hup2 [H]

Identifier: 159900715

GI number: 159900715

Start: 5357283

End: 5357570

Strand: Reverse

Name: hup2 [H]

Synonym: Haur_4202

Alternate gene names: 159900715

Gene position: 5357570-5357283 (Counterclockwise)

Preceding gene: 159900718

Following gene: 159900714

Centisome position: 84.42

GC content: 52.78

Gene sequence:

>288_bases
ATGCAAAAAATCGAGTTCATTGCTGAGGTCGCTGAACGCACCGGCATTTCTAAAAAAGAGGCACGCCGCGTTGTCGATGC
TATGTTGGATGTGGTCAGCGAGCGCTTGCAAGCTGGCGAAAAAGTGGTCTTGACTGGGTTTGGTACCTTTGAAGTCCGTG
AGCGCCAAGCTCGCCAAGGGGTCAACCCCAAAACCCGCGAACGTATGACAATCGAAGCTACCAAAACCCCTGGCTTCTCG
GCCAGTAATAGCTTGAAACTGCTGGTTCGCCAAGGCAAGCCTGAGTAG

Upstream 100 bases:

>100_bases
AATTGGCCTATCTAATGGGCTAAAATGTTCCACAGCGCTTAATCCTTATGGTATAATCGACGGTAATGATTGTAGCTTCG
CTAGGATTAAGGAGCGTGCA

Downstream 100 bases:

>100_bases
CACGCGTCGTAGCAGATGTTGCTTTGAGCGACCGCCAATTGCTTGCGGTCGCTTTCTTGTGTTATAACCCTAGGGTGATA
TGTTTTCACGATTCTTTAGT

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MQKIEFIAEVAERTGISKKEARRVVDAMLDVVSERLQAGEKVVLTGFGTFEVRERQARQGVNPKTRERMTIEATKTPGFS
ASNSLKLLVRQGKPE

Sequences:

>Translated_95_residues
MQKIEFIAEVAERTGISKKEARRVVDAMLDVVSERLQAGEKVVLTGFGTFEVRERQARQGVNPKTRERMTIEATKTPGFS
ASNSLKLLVRQGKPE
>Mature_95_residues
MQKIEFIAEVAERTGISKKEARRVVDAMLDVVSERLQAGEKVVLTGFGTFEVRERQARQGVNPKTRERMTIEATKTPGFS
ASNSLKLLVRQGKPE

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=86, Percent_Identity=46.5116279069767, Blast_Score=79, Evalue=5e-17,
Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=36.6666666666667, Blast_Score=67, Evalue=3e-13,
Organism=Escherichia coli, GI1788005, Length=94, Percent_Identity=32.9787234042553, Blast_Score=60, Evalue=3e-11,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 10632; Mature: 10632

Theoretical pI: Translated: 10.76; Mature: 10.76

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKIEFIAEVAERTGISKKEARRVVDAMLDVVSERLQAGEKVVLTGFGTFEVRERQARQG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCC
VNPKTRERMTIEATKTPGFSASNSLKLLVRQGKPE
CCCCCCCEEEEEECCCCCCCCCCHHHHEEECCCCC
>Mature Secondary Structure
MQKIEFIAEVAERTGISKKEARRVVDAMLDVVSERLQAGEKVVLTGFGTFEVRERQARQG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCC
VNPKTRERMTIEATKTPGFSASNSLKLLVRQGKPE
CCCCCCCEEEEEECCCCCCCCCCHHHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]