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The map label for this gene is argG [H]

Identifier: 159900653

GI number: 159900653

Start: 5288246

End: 5289457

Strand: Reverse

Name: argG [H]

Synonym: Haur_4140

Alternate gene names: 159900653

Gene position: 5289457-5288246 (Counterclockwise)

Preceding gene: 159900654

Following gene: 159900652

Centisome position: 83.34

GC content: 51.65

Gene sequence:

>1212_bases
ATGTCGAATGCGACTGCAAATAAAGTTGTGCTGGCCTACTCTGGTGGTTTGGATACCAGCGTGATCGTGCCGTGGTTGAA
GGAACACTATGGCTGTGAAGTCGTCTGCTATTGCGCCAATCTTGGCCAAGATGACGATCTGAGCGGCGTAGAGGCCAAAG
CGATTGCTTCGGGCGCAAGTGCCTGCTATGTCGAAGATTTGCGCGAAGAATTTGTGCGCGATTTCTTGTTCCCGATGTTG
CAATCAGGTGCAACCTACGAACGCACCTACTTGCTCGGCACAAGCATCGCCCGCCCATTGATCGCTCGTGGTCAGGTGCA
AACCGCCTTGAAAGTTGGCGCTGATGCACTTTCTCACGGCTGCACGGGCAAAGGCAACGATCAAGTGCGCTTTGAATTGA
CCTACATGGCCTTGGCTCCGCATATGAAAATTATCGCCCCATGGCGTGAATGGCATATTCGCTCACGGGAAGATGCATTG
GATTATGCTGCATTACATAATGTGCCAGTCACCAGCACTCGCGCCTCGATCTACAGTCGCGATGGCAATATTTGGCACTT
GAGCCATGAAGGTGGCTCGTTGGAAGATCCATGGTTAGAACCAGAATTGACCATGTTCCAACGCACCGTGACCCCTGAAG
AAGCTCCCGATTTACCAGAATACTTGGAAATTGGCTTCGAACGTGGTATTCCGGTGAGTGTGAATGGCGAGCAACTTGGC
CCCGTGGCGTTGCTGCAAACCCTTAACGACATTGGCGCTCGTCATGGCGTTGGTCGCGTCGATTTGGTCGAAAATCGCTT
GGTTGGCATGAAAAGCCATGGCGTATACGAAACACCAGGCGGTACATTGCTCTATCGTGCCCACCAAGGCCTCGAAGAAT
TGGCGCTTGATCGCGAAACCTTGCACTTCAAAGATACCTTGGCAATCCGCTTCTCAGAGTTGATTTACAACGGTCAATGG
TGGTCGCCGTTGCGCTATGCCTTGTCGGCCTTCTTCACTGAAACCCAAAAGAACGTTACAGGCGTGACTCGCTTGAAAGT
CTTCAAAGGTGGCGTGTATTTGGTTGGGCGCAAGGCTGAACGCAGCTTGTACGTACCCGATTTGGCAACCTTCAGCGAAG
ATGCCGTTTATAACCAAGCCGATGCTGAAGGCTTTATCAAGCTCTTTGGCTTGCCTCAAAAAGTCGAAGCCTTAACCTCA
GGAGCCGAATAA

Upstream 100 bases:

>100_bases
AAAATCAAAATGTCCCTATGAAGCATTACAATTCGATGATTAGCCTACGATTTTGCCTTTTGCTTTTTGCCTTCTGCCTT
TCATAAGGAGTTCATTGGTC

Downstream 100 bases:

>100_bases
GCATGAGTATCTTTCGTTTTGCCGCCGGCTTCCGCAGTGCTGCGGGGCGATGTGGCTTGAAGGCCAGTGGTAATCCTGAT
TTAAGCTTACTTGTTGCTGA

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSNATANKVVLAYSGGLDTSVIVPWLKEHYGCEVVCYCANLGQDDDLSGVEAKAIASGASACYVEDLREEFVRDFLFPML
QSGATYERTYLLGTSIARPLIARGQVQTALKVGADALSHGCTGKGNDQVRFELTYMALAPHMKIIAPWREWHIRSREDAL
DYAALHNVPVTSTRASIYSRDGNIWHLSHEGGSLEDPWLEPELTMFQRTVTPEEAPDLPEYLEIGFERGIPVSVNGEQLG
PVALLQTLNDIGARHGVGRVDLVENRLVGMKSHGVYETPGGTLLYRAHQGLEELALDRETLHFKDTLAIRFSELIYNGQW
WSPLRYALSAFFTETQKNVTGVTRLKVFKGGVYLVGRKAERSLYVPDLATFSEDAVYNQADAEGFIKLFGLPQKVEALTS
GAE

Sequences:

>Translated_403_residues
MSNATANKVVLAYSGGLDTSVIVPWLKEHYGCEVVCYCANLGQDDDLSGVEAKAIASGASACYVEDLREEFVRDFLFPML
QSGATYERTYLLGTSIARPLIARGQVQTALKVGADALSHGCTGKGNDQVRFELTYMALAPHMKIIAPWREWHIRSREDAL
DYAALHNVPVTSTRASIYSRDGNIWHLSHEGGSLEDPWLEPELTMFQRTVTPEEAPDLPEYLEIGFERGIPVSVNGEQLG
PVALLQTLNDIGARHGVGRVDLVENRLVGMKSHGVYETPGGTLLYRAHQGLEELALDRETLHFKDTLAIRFSELIYNGQW
WSPLRYALSAFFTETQKNVTGVTRLKVFKGGVYLVGRKAERSLYVPDLATFSEDAVYNQADAEGFIKLFGLPQKVEALTS
GAE
>Mature_402_residues
SNATANKVVLAYSGGLDTSVIVPWLKEHYGCEVVCYCANLGQDDDLSGVEAKAIASGASACYVEDLREEFVRDFLFPMLQ
SGATYERTYLLGTSIARPLIARGQVQTALKVGADALSHGCTGKGNDQVRFELTYMALAPHMKIIAPWREWHIRSREDALD
YAALHNVPVTSTRASIYSRDGNIWHLSHEGGSLEDPWLEPELTMFQRTVTPEEAPDLPEYLEIGFERGIPVSVNGEQLGP
VALLQTLNDIGARHGVGRVDLVENRLVGMKSHGVYETPGGTLLYRAHQGLEELALDRETLHFKDTLAIRFSELIYNGQWW
SPLRYALSAFFTETQKNVTGVTRLKVFKGGVYLVGRKAERSLYVPDLATFSEDAVYNQADAEGFIKLFGLPQKVEALTSG
AE

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=397, Percent_Identity=44.8362720403023, Blast_Score=345, Evalue=3e-95,
Organism=Homo sapiens, GI16950633, Length=397, Percent_Identity=44.8362720403023, Blast_Score=345, Evalue=3e-95,
Organism=Escherichia coli, GI1789563, Length=409, Percent_Identity=27.1393643031785, Blast_Score=128, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6324514, Length=399, Percent_Identity=42.3558897243108, Blast_Score=313, Evalue=4e-86,
Organism=Drosophila melanogaster, GI21358151, Length=394, Percent_Identity=43.1472081218274, Blast_Score=311, Evalue=7e-85,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 44563; Mature: 44432

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNATANKVVLAYSGGLDTSVIVPWLKEHYGCEVVCYCANLGQDDDLSGVEAKAIASGAS
CCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCC
ACYVEDLREEFVRDFLFPMLQSGATYERTYLLGTSIARPLIARGQVQTALKVGADALSHG
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHCC
CTGKGNDQVRFELTYMALAPHMKIIAPWREWHIRSREDALDYAALHNVPVTSTRASIYSR
CCCCCCCEEEEEEEEEECCCCCEEEECHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHEEC
DGNIWHLSHEGGSLEDPWLEPELTMFQRTVTPEEAPDLPEYLEIGFERGIPVSVNGEQLG
CCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEECCCCCC
PVALLQTLNDIGARHGVGRVDLVENRLVGMKSHGVYETPGGTLLYRAHQGLEELALDRET
HHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCCCCCEECCCCEEEEHHHCCHHHHHCCHHH
LHFKDTLAIRFSELIYNGQWWSPLRYALSAFFTETQKNVTGVTRLKVFKGGVYLVGRKAE
HHHHHHHHHEEHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHEEEEEEECCEEEEEECCC
RSLYVPDLATFSEDAVYNQADAEGFIKLFGLPQKVEALTSGAE
CEEECCCHHHCCCCHHCCCCCCCCHHEECCCCHHHHHHHCCCC
>Mature Secondary Structure 
SNATANKVVLAYSGGLDTSVIVPWLKEHYGCEVVCYCANLGQDDDLSGVEAKAIASGAS
CCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCC
ACYVEDLREEFVRDFLFPMLQSGATYERTYLLGTSIARPLIARGQVQTALKVGADALSHG
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHCC
CTGKGNDQVRFELTYMALAPHMKIIAPWREWHIRSREDALDYAALHNVPVTSTRASIYSR
CCCCCCCEEEEEEEEEECCCCCEEEECHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHEEC
DGNIWHLSHEGGSLEDPWLEPELTMFQRTVTPEEAPDLPEYLEIGFERGIPVSVNGEQLG
CCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEECCCCCC
PVALLQTLNDIGARHGVGRVDLVENRLVGMKSHGVYETPGGTLLYRAHQGLEELALDRET
HHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCCCCCEECCCCEEEEHHHCCHHHHHCCHHH
LHFKDTLAIRFSELIYNGQWWSPLRYALSAFFTETQKNVTGVTRLKVFKGGVYLVGRKAE
HHHHHHHHHEEHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHEEEEEEECCEEEEEECCC
RSLYVPDLATFSEDAVYNQADAEGFIKLFGLPQKVEALTSGAE
CEEECCCHHHCCCCHHCCCCCCCCHHEECCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA