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The map label for this gene is degP1 [H]

Identifier: 159900603

GI number: 159900603

Start: 5223030

End: 5223905

Strand: Direct

Name: degP1 [H]

Synonym: Haur_4090

Alternate gene names: 159900603

Gene position: 5223030-5223905 (Clockwise)

Preceding gene: 159900602

Following gene: 159900604

Centisome position: 82.3

GC content: 55.59

Gene sequence:

>876_bases
ATGAGCTTACAAGAATTTTCGAGCGAACTAGCTGATGCCGTGGAACAGAGCGGGGCAGGCATCGTGACGATCTATGCTCG
CCGTCGCCAAAGTGCCAGCGGGATCGTTTGGCAAGCTGATTTGGTGCTGACCGCTGATCATGTCATCCAACGCGATGAGC
ATATCAAGGTGGTTGGGCCAGATGGCACGGAGTATCAAGCCCACGTCGTTGGTCGCGACCCGAGCAGCGATGTGGCGTTG
CTGCGCGTGCCCAACGCCAATTTTCCCCCCGCAACTTTGGCCAAAACCGAGCCACGGGTTGGTCAGTTGGCCTTGGCAGT
CGGTCGTCCAAGCACGGTACAAGCCAGTTTTGGTATTATTAATGCGATTGGCGGCCCAGTCCCAACCCGCCGTGGCACAT
TAGCTCAATATTTGCGCACCGATGCCACCCCATATCCAGGCTTCTCGGGGGGCGGCTTGGTCAATGTTAAAGGTGAAGTC
GTTGGTTTGTTTACTTCCGGCTTTGCAGGCGGCGAGCCAATTGCAATTCCAGTGGCTGTGCTGACCAGCGTCGCCGATAC
CTTGCTCAACCATGGCCGCGTGCGCCGTGGCTTTATCGGGATTGCCAGCCAAACTGTCAATTTGCCCGATAACCAACGCG
CTGGCCGCAACCAAGCGACTGGTCTGTTGGTGATTAGCGTCGAAGCCGATAGCCCAGCTCAACACGCTGGCTTGTTGGTT
GGCGATATTTTGGTGGGCTTAGATGGCCATGAATTGGGTGAACCACGCGATTTGCAAATGCTCTTGGCAAGCGATCGAGC
GGGCAAGACTGTAACGCTTGATGTGCTACGAGCTGGCCAATTGCAAAACCTGAGCATCACAATTGGAGCAAAATAG

Upstream 100 bases:

>100_bases
AACTAGTCATTTGGCTAGGTTGAAACCTCGCTGGCTGACTGATCTCAAGCAGATTGTGCTTGGCTATACTGCTCAACAGT
TAATCATTTAGGAGGCTGTT

Downstream 100 bases:

>100_bases
CCCTTGAGCGAAGCAGGATTAAAACTCATGTTGATTGGCGGAACGACGCTGACTCGCGCGGGTATGCGCAGTGTGTTGGC
CGAGTACGAGGCCGAAATTG

Product: peptidase S1 and S6 chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSLQEFSSELADAVEQSGAGIVTIYARRRQSASGIVWQADLVLTADHVIQRDEHIKVVGPDGTEYQAHVVGRDPSSDVAL
LRVPNANFPPATLAKTEPRVGQLALAVGRPSTVQASFGIINAIGGPVPTRRGTLAQYLRTDATPYPGFSGGGLVNVKGEV
VGLFTSGFAGGEPIAIPVAVLTSVADTLLNHGRVRRGFIGIASQTVNLPDNQRAGRNQATGLLVISVEADSPAQHAGLLV
GDILVGLDGHELGEPRDLQMLLASDRAGKTVTLDVLRAGQLQNLSITIGAK

Sequences:

>Translated_291_residues
MSLQEFSSELADAVEQSGAGIVTIYARRRQSASGIVWQADLVLTADHVIQRDEHIKVVGPDGTEYQAHVVGRDPSSDVAL
LRVPNANFPPATLAKTEPRVGQLALAVGRPSTVQASFGIINAIGGPVPTRRGTLAQYLRTDATPYPGFSGGGLVNVKGEV
VGLFTSGFAGGEPIAIPVAVLTSVADTLLNHGRVRRGFIGIASQTVNLPDNQRAGRNQATGLLVISVEADSPAQHAGLLV
GDILVGLDGHELGEPRDLQMLLASDRAGKTVTLDVLRAGQLQNLSITIGAK
>Mature_290_residues
SLQEFSSELADAVEQSGAGIVTIYARRRQSASGIVWQADLVLTADHVIQRDEHIKVVGPDGTEYQAHVVGRDPSSDVALL
RVPNANFPPATLAKTEPRVGQLALAVGRPSTVQASFGIINAIGGPVPTRRGTLAQYLRTDATPYPGFSGGGLVNVKGEVV
GLFTSGFAGGEPIAIPVAVLTSVADTLLNHGRVRRGFIGIASQTVNLPDNQRAGRNQATGLLVISVEADSPAQHAGLLVG
DILVGLDGHELGEPRDLQMLLASDRAGKTVTLDVLRAGQLQNLSITIGAK

Specific function: Unknown

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=316, Percent_Identity=28.4810126582279, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI22129776, Length=283, Percent_Identity=29.6819787985866, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI24308541, Length=289, Percent_Identity=26.9896193771626, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI7019477, Length=317, Percent_Identity=27.7602523659306, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1789630, Length=314, Percent_Identity=31.5286624203822, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789629, Length=267, Percent_Identity=31.8352059925094, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1786356, Length=273, Percent_Identity=31.5018315018315, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24646839, Length=279, Percent_Identity=29.7491039426523, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 30368; Mature: 30237

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQEFSSELADAVEQSGAGIVTIYARRRQSASGIVWQADLVLTADHVIQRDEHIKVVGP
CCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEEEEEEHHHHHCCCCEEEEECC
DGTEYQAHVVGRDPSSDVALLRVPNANFPPATLAKTEPRVGQLALAVGRPSTVQASFGII
CCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCH
NAIGGPVPTRRGTLAQYLRTDATPYPGFSGGGLVNVKGEVVGLFTSGFAGGEPIAIPVAV
HHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEECCEEEEEEECCCCCCCCEEHHHHH
LTSVADTLLNHGRVRRGFIGIASQTVNLPDNQRAGRNQATGLLVISVEADSPAQHAGLLV
HHHHHHHHHHCCCEEEEEEEEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCHHHHCEEE
GDILVGLDGHELGEPRDLQMLLASDRAGKTVTLDVLRAGQLQNLSITIGAK
EHEEEECCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCEEEEEEECC
>Mature Secondary Structure 
SLQEFSSELADAVEQSGAGIVTIYARRRQSASGIVWQADLVLTADHVIQRDEHIKVVGP
CHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEEEEEEHHHHHCCCCEEEEECC
DGTEYQAHVVGRDPSSDVALLRVPNANFPPATLAKTEPRVGQLALAVGRPSTVQASFGII
CCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCH
NAIGGPVPTRRGTLAQYLRTDATPYPGFSGGGLVNVKGEVVGLFTSGFAGGEPIAIPVAV
HHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEECCEEEEEEECCCCCCCCEEHHHHH
LTSVADTLLNHGRVRRGFIGIASQTVNLPDNQRAGRNQATGLLVISVEADSPAQHAGLLV
HHHHHHHHHHCCCEEEEEEEEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCHHHHCEEE
GDILVGLDGHELGEPRDLQMLLASDRAGKTVTLDVLRAGQLQNLSITIGAK
EHEEEECCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550509; 11481430 [H]