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The map label for this gene is prpC [H]

Identifier: 159900555

GI number: 159900555

Start: 5160867

End: 5162036

Strand: Direct

Name: prpC [H]

Synonym: Haur_4042

Alternate gene names: 159900555

Gene position: 5160867-5162036 (Clockwise)

Preceding gene: 159900554

Following gene: 159900556

Centisome position: 81.32

GC content: 55.38

Gene sequence:

>1170_bases
ATGGGATTTTTTCGTAAATTATTCGGGCGTACTTCAACTGAGCCAAGCACGCTTGATCCAGCTTCTACTACAACCGATCA
GTTACCTGTTGCTGTCGCTAGCCCAGTTGCTAGCGAGGCATTAGCCGAAACGCCAATCGAGGTTGTTGCGGTTGCTGCAA
CTGAGGTACCAACCGAGCCATTGATCAGCGCCGAGCCACTGGCCGAATTGCCAGCAGCCCAAACTGCTGGCGCGGTGGCA
ACCGAGCGTTCGCAAAAAACGACCGCGCCACTTGACCCTGAGCAACTGCCCGAGCGCGATCCTGATGGCACGAATTATCT
CGGAACCCGCGATATTAGTGCTGCGCCGATCGTTGCTAAAGCGGTCTCAACCCGTGGGCTAGCCAGTTGGGCCGCCCGCG
ATATTGGCCGCATTCGCCGTAATAATCAAGATAGTGTTTACACAAGCTTGATGAGTTTGCCCGATGGCGAGCACGATATC
AGCGTGGGCCTGTTTGTGGTTGCCGACGGCATGGGTGGCCACGAAGGCGGCGAAATCGCCTCGCGCCGTGCGATCGAAAC
CGTGATGATCGCGGTGTTGGAGCAAATGGCCTTGCCAGCAATGGCCGATGAAGATCCTGGTAACCCACTGCCCTTGCTGA
TGATGAGCGCCGTGCAAGATGCCAACACCCGCATCTGGAACGAAGCTCAATCGCGTGGCACCGATATGGGCACGACCTGT
ACTGCTGCCTTATTGGTTGGCGATGGCTTGTATATTGCCCATGTTGGCGATAGTCGCCTATATGCCATGAGCGATGGCAA
ACTCCGCCTGATCACCGCTGATCATTCCACCGTGGGGCGCTTGATTGCGATGGGTCAATTGACCGAAGAAGAAACCCGCA
ATCACCCGCTGCGCAACCAACTCTATCGCACCGTTGGCCAACATCCGGAGATCCAAGTCGATTCAATCTACCAAAGCCTT
GAGGGTATCAGCCATTTGTTATTGTGTAGCGATGGCTTATGGAGTATGGTTGACGACGATGAGATGGCTGCAATCATCAA
CGAAACGCCATGGCCGCAAGATGCCTGCCAGCGTTTGATTGCCCGCGCCAACTTAGCCGGTGGCGAAGATAACATTAGCG
CGGTGGTTGTTTCATTGCCACCCTTGCAAGGCCAAGGAGCGCTCCGATGA

Upstream 100 bases:

>100_bases
AAGGCCCAATCGTTTCGACCCCAGCGGTTGTTGAAGGGGTCGTCTATATCGGGTCGATGGATCACCAGGTCTATGCCTTA
CGTGCTTAGGAGAGTCCGCC

Downstream 100 bases:

>100_bases
GTACCCAAGCAATGGTTCAACTGCGCATCACCCCTGGGCGGCCAGCAGTTGCCCAAAGTAACGATCCGCAAATTGTTTAT
TTGTTGGTCGAAGCCTCGCC

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MGFFRKLFGRTSTEPSTLDPASTTTDQLPVAVASPVASEALAETPIEVVAVAATEVPTEPLISAEPLAELPAAQTAGAVA
TERSQKTTAPLDPEQLPERDPDGTNYLGTRDISAAPIVAKAVSTRGLASWAARDIGRIRRNNQDSVYTSLMSLPDGEHDI
SVGLFVVADGMGGHEGGEIASRRAIETVMIAVLEQMALPAMADEDPGNPLPLLMMSAVQDANTRIWNEAQSRGTDMGTTC
TAALLVGDGLYIAHVGDSRLYAMSDGKLRLITADHSTVGRLIAMGQLTEEETRNHPLRNQLYRTVGQHPEIQVDSIYQSL
EGISHLLLCSDGLWSMVDDDEMAAIINETPWPQDACQRLIARANLAGGEDNISAVVVSLPPLQGQGALR

Sequences:

>Translated_389_residues
MGFFRKLFGRTSTEPSTLDPASTTTDQLPVAVASPVASEALAETPIEVVAVAATEVPTEPLISAEPLAELPAAQTAGAVA
TERSQKTTAPLDPEQLPERDPDGTNYLGTRDISAAPIVAKAVSTRGLASWAARDIGRIRRNNQDSVYTSLMSLPDGEHDI
SVGLFVVADGMGGHEGGEIASRRAIETVMIAVLEQMALPAMADEDPGNPLPLLMMSAVQDANTRIWNEAQSRGTDMGTTC
TAALLVGDGLYIAHVGDSRLYAMSDGKLRLITADHSTVGRLIAMGQLTEEETRNHPLRNQLYRTVGQHPEIQVDSIYQSL
EGISHLLLCSDGLWSMVDDDEMAAIINETPWPQDACQRLIARANLAGGEDNISAVVVSLPPLQGQGALR
>Mature_388_residues
GFFRKLFGRTSTEPSTLDPASTTTDQLPVAVASPVASEALAETPIEVVAVAATEVPTEPLISAEPLAELPAAQTAGAVAT
ERSQKTTAPLDPEQLPERDPDGTNYLGTRDISAAPIVAKAVSTRGLASWAARDIGRIRRNNQDSVYTSLMSLPDGEHDIS
VGLFVVADGMGGHEGGEIASRRAIETVMIAVLEQMALPAMADEDPGNPLPLLMMSAVQDANTRIWNEAQSRGTDMGTTCT
AALLVGDGLYIAHVGDSRLYAMSDGKLRLITADHSTVGRLIAMGQLTEEETRNHPLRNQLYRTVGQHPEIQVDSIYQSLE
GISHLLLCSDGLWSMVDDDEMAAIINETPWPQDACQRLIARANLAGGEDNISAVVVSLPPLQGQGALR

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 41395; Mature: 41264

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFFRKLFGRTSTEPSTLDPASTTTDQLPVAVASPVASEALAETPIEVVAVAATEVPTEP
CCHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHCCHHEEEEEHHCCCCCC
LISAEPLAELPAAQTAGAVATERSQKTTAPLDPEQLPERDPDGTNYLGTRDISAAPIVAK
CCCCCCHHHCCCHHHCCHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHH
AVSTRGLASWAARDIGRIRRNNQDSVYTSLMSLPDGEHDISVGLFVVADGMGGHEGGEIA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCHHH
SRRAIETVMIAVLEQMALPAMADEDPGNPLPLLMMSAVQDANTRIWNEAQSRGTDMGTTC
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
TAALLVGDGLYIAHVGDSRLYAMSDGKLRLITADHSTVGRLIAMGQLTEEETRNHPLRNQ
HHHHHCCCCEEEEEECCCEEEEECCCCEEEEECCCHHHHHHHHHHCCCHHHHHCCCHHHH
LYRTVGQHPEIQVDSIYQSLEGISHLLLCSDGLWSMVDDDEMAAIINETPWPQDACQRLI
HHHHHCCCCCEEHHHHHHHHHHHHEEEHCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHH
ARANLAGGEDNISAVVVSLPPLQGQGALR
HHHCCCCCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
GFFRKLFGRTSTEPSTLDPASTTTDQLPVAVASPVASEALAETPIEVVAVAATEVPTEP
CHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHCCHHEEEEEHHCCCCCC
LISAEPLAELPAAQTAGAVATERSQKTTAPLDPEQLPERDPDGTNYLGTRDISAAPIVAK
CCCCCCHHHCCCHHHCCHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHH
AVSTRGLASWAARDIGRIRRNNQDSVYTSLMSLPDGEHDISVGLFVVADGMGGHEGGEIA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCHHH
SRRAIETVMIAVLEQMALPAMADEDPGNPLPLLMMSAVQDANTRIWNEAQSRGTDMGTTC
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
TAALLVGDGLYIAHVGDSRLYAMSDGKLRLITADHSTVGRLIAMGQLTEEETRNHPLRNQ
HHHHHCCCCEEEEEECCCEEEEECCCCEEEEECCCHHHHHHHHHHCCCHHHHHCCCHHHH
LYRTVGQHPEIQVDSIYQSLEGISHLLLCSDGLWSMVDDDEMAAIINETPWPQDACQRLI
HHHHHCCCCCEEHHHHHHHHHHHHEEEHCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHH
ARANLAGGEDNISAVVVSLPPLQGQGALR
HHHCCCCCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]