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The map label for this gene is crtI [H]

Identifier: 159900537

GI number: 159900537

Start: 5135588

End: 5137231

Strand: Direct

Name: crtI [H]

Synonym: Haur_4024

Alternate gene names: 159900537

Gene position: 5135588-5137231 (Clockwise)

Preceding gene: 159900536

Following gene: 159900538

Centisome position: 80.92

GC content: 53.16

Gene sequence:

>1644_bases
ATGGCGCAATTTGATGCGATTGTGGTTGGCGGTGGGCATAATGGCTTGACCTGTGCCTGCTATTTGCAAAAGGCCGGAAT
CAAAACCCTAGTGATCGAACGACGAGCGATCGTCGGCGGCGCAGTTTGCACCGAAACCATGTTTGGTGGCTATAAGATGG
ATGTTGGCTCATCGGCCCACATTATGATTCACCTGACTCCTGTAGTGCGTGAGCTTGAACTGCACAAATTTGGGCTTGAA
TATATTGATATGGACCCATTTGCTTGGTATCCATTGCCCGATGGCTCGGGGGCAATTGAATTTTGGCGTGATTTAGACAA
GACGTGTGCTTCGATTGAGAAAATTTCACCCAAGGATGCCCATGCTTATCGCCAATTTGTGGCGTTGTGGGGGCCGCTCA
ATGAAGGGGTTTTCGATGTATTTCTCAAAGCACCTTCGCCTGCCAACTTAGGCCGCCAAATGCTAACGGGCCAATTCAAA
GGCGAAAAAGGCACGCATCCGCTGGATATTCTGCGGCGCTTGTTTACCTCGTATGGACATTTGATCAACGAAACCTTTGA
GAGCGAAGCAATGCGGGCAGCAATGGGATGGCTAGCAGCGCAATCTGGCCCACCACCGCACGAAATTGGCACCGGCGATT
TTGCGGGCTGGCACGCGATGCTGCATGAAAGTGGCGCGAAACATCCGCGTGGTGGTTCGGGCATGTTGACCCAAGCCATG
GCGGCACGCTTCAAAAGTGATGGCGGTACGCTGCTGCTTGATGCCCCAGTTGAACGGATTGTGGTGCAAAACGGCGTAGT
GCACGGCGTACAATTAACCTCGGGCGAAACTTACACCGCACCAACGGTTATTTCCAATGCCCATGTGCAAACCACCTTAT
TAAAACTGGTTGAGCCTGAGCAACTGCCAAATGGTCTGGTCGAGCGGGTTGGCCGCATTCGCGTTGGCAATGGCTTTGGG
ATGGCGGTGCGCTGTGCTGCCGATGAATTGCCCGATTATCTGGCTGCGCCTTCTGGTGGTCGCCCGCATCCTTCACATCA
TGGGTTGCAATTGCTTTGCCCTTCGATCGACTACCTGAATCGCGCGGTTAGCGATTATGATCGCGGCGTGCCAGCGACCG
ATCCAGCGGTAATTGCCATGACATTTAGTGCAATCGACCCCGATGTTGCACCCAAGGGCAAGCATACGCTGTTTTTGTGG
GGTCAATATCATCCGTATCAATTAAGTAATGGCGAAGATTGGGATAGCATTGCCGAGCGCGAGGCCGACAAATTACTCGA
AGTCGTGTATCGTTATGCCCCCAATATGCGTGGCAAAATTAGCAACCGCTATGTGCAAACTCCCTTAACCTTGGAGCGCA
CCTTTGGCATGTTGCGTGGTAATGTGATGCATGTCGAAATGTCGTTCGATCAGATGTTTGCCTTCCGCCCGCTGCCTGAG
CTTTCCGAATACCGCGTGGCGGGAATTAAGGGCTTATATTTGACCGGAGCCAGCACCCATCCTGGTGGCGGCGTATTTGC
GGCCTCAGGTTACAACACCGCCCAAACCGTGCTCAAAGATCAGCAGCCATCACGTCAATGGGTTGGCTGGACGCTCGGGG
CGGCTGCCGCTTTAGGTGTGGTGGCTTGGGCCAAGAAGAAGTAA

Upstream 100 bases:

>100_bases
TTGGCCTGATGTTGGCTTGGTTACGACGGCAGTATGATACGTCCAAAGCCCAAATGCATGCGTAGCATAACAATATCAAT
AGTGTGGGGTGATGCTCAAA

Downstream 100 bases:

>100_bases
ATTGCTACGATAAACCGCCAAGTTTATAGCTTGGCGGTTTATCTTTTAAAATTAAACTTGTTGTTCCTGTTTTCAAGTTC
GGACAATTCGTAAAAACCGT

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Phytoene desaturase [H]

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MAQFDAIVVGGGHNGLTCACYLQKAGIKTLVIERRAIVGGAVCTETMFGGYKMDVGSSAHIMIHLTPVVRELELHKFGLE
YIDMDPFAWYPLPDGSGAIEFWRDLDKTCASIEKISPKDAHAYRQFVALWGPLNEGVFDVFLKAPSPANLGRQMLTGQFK
GEKGTHPLDILRRLFTSYGHLINETFESEAMRAAMGWLAAQSGPPPHEIGTGDFAGWHAMLHESGAKHPRGGSGMLTQAM
AARFKSDGGTLLLDAPVERIVVQNGVVHGVQLTSGETYTAPTVISNAHVQTTLLKLVEPEQLPNGLVERVGRIRVGNGFG
MAVRCAADELPDYLAAPSGGRPHPSHHGLQLLCPSIDYLNRAVSDYDRGVPATDPAVIAMTFSAIDPDVAPKGKHTLFLW
GQYHPYQLSNGEDWDSIAEREADKLLEVVYRYAPNMRGKISNRYVQTPLTLERTFGMLRGNVMHVEMSFDQMFAFRPLPE
LSEYRVAGIKGLYLTGASTHPGGGVFAASGYNTAQTVLKDQQPSRQWVGWTLGAAAALGVVAWAKKK

Sequences:

>Translated_547_residues
MAQFDAIVVGGGHNGLTCACYLQKAGIKTLVIERRAIVGGAVCTETMFGGYKMDVGSSAHIMIHLTPVVRELELHKFGLE
YIDMDPFAWYPLPDGSGAIEFWRDLDKTCASIEKISPKDAHAYRQFVALWGPLNEGVFDVFLKAPSPANLGRQMLTGQFK
GEKGTHPLDILRRLFTSYGHLINETFESEAMRAAMGWLAAQSGPPPHEIGTGDFAGWHAMLHESGAKHPRGGSGMLTQAM
AARFKSDGGTLLLDAPVERIVVQNGVVHGVQLTSGETYTAPTVISNAHVQTTLLKLVEPEQLPNGLVERVGRIRVGNGFG
MAVRCAADELPDYLAAPSGGRPHPSHHGLQLLCPSIDYLNRAVSDYDRGVPATDPAVIAMTFSAIDPDVAPKGKHTLFLW
GQYHPYQLSNGEDWDSIAEREADKLLEVVYRYAPNMRGKISNRYVQTPLTLERTFGMLRGNVMHVEMSFDQMFAFRPLPE
LSEYRVAGIKGLYLTGASTHPGGGVFAASGYNTAQTVLKDQQPSRQWVGWTLGAAAALGVVAWAKKK
>Mature_546_residues
AQFDAIVVGGGHNGLTCACYLQKAGIKTLVIERRAIVGGAVCTETMFGGYKMDVGSSAHIMIHLTPVVRELELHKFGLEY
IDMDPFAWYPLPDGSGAIEFWRDLDKTCASIEKISPKDAHAYRQFVALWGPLNEGVFDVFLKAPSPANLGRQMLTGQFKG
EKGTHPLDILRRLFTSYGHLINETFESEAMRAAMGWLAAQSGPPPHEIGTGDFAGWHAMLHESGAKHPRGGSGMLTQAMA
ARFKSDGGTLLLDAPVERIVVQNGVVHGVQLTSGETYTAPTVISNAHVQTTLLKLVEPEQLPNGLVERVGRIRVGNGFGM
AVRCAADELPDYLAAPSGGRPHPSHHGLQLLCPSIDYLNRAVSDYDRGVPATDPAVIAMTFSAIDPDVAPKGKHTLFLWG
QYHPYQLSNGEDWDSIAEREADKLLEVVYRYAPNMRGKISNRYVQTPLTLERTFGMLRGNVMHVEMSFDQMFAFRPLPEL
SEYRVAGIKGLYLTGASTHPGGGVFAASGYNTAQTVLKDQQPSRQWVGWTLGAAAALGVVAWAKKK

Specific function: This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds [H]

COG id: COG1233

COG function: function code Q; Phytoene dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid/retinoid oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI229577391, Length=552, Percent_Identity=31.8840579710145, Blast_Score=257, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI17540238, Length=539, Percent_Identity=30.9833024118738, Blast_Score=228, Evalue=9e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR008150
- InterPro:   IPR014105 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 59584; Mature: 59453

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQFDAIVVGGGHNGLTCACYLQKAGIKTLVIERRAIVGGAVCTETMFGGYKMDVGSSAH
CCCEEEEEEECCCCCCEEEEEEECCCCEEEEEEHHHHHCHHHHHHHHCCCEEECCCCCCE
IMIHLTPVVRELELHKFGLEYIDMDPFAWYPLPDGSGAIEFWRDLDKTCASIEKISPKDA
EEEEECHHHHHHHHHHHCCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHH
HAYRQFVALWGPLNEGVFDVFLKAPSPANLGRQMLTGQFKGEKGTHPLDILRRLFTSYGH
HHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
LINETFESEAMRAAMGWLAAQSGPPPHEIGTGDFAGWHAMLHESGAKHPRGGSGMLTQAM
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHH
AARFKSDGGTLLLDAPVERIVVQNGVVHGVQLTSGETYTAPTVISNAHVQTTLLKLVEPE
HHHHCCCCCEEEECCCHHHHHHHCCCEEEEEEECCCCEECCCEECCCHHHHHHHHHHCHH
QLPNGLVERVGRIRVGNGFGMAVRCAADELPDYLAAPSGGRPHPSHHGLQLLCPSIDYLN
HCCCHHHHHHCEEEECCCCCEEEEECHHHCCHHHCCCCCCCCCCCCCCCEEECCCHHHHH
RAVSDYDRGVPATDPAVIAMTFSAIDPDVAPKGKHTLFLWGQYHPYQLSNGEDWDSIAER
HHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEEECCCCEECCCCCCHHHHHHH
EADKLLEVVYRYAPNMRGKISNRYVQTPLTLERTFGMLRGNVMHVEMSFDQMFAFRPLPE
HHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHHCCCEEEEEECHHHHHHCCCCCC
LSEYRVAGIKGLYLTGASTHPGGGVFAASGYNTAQTVLKDQQPSRQWVGWTLGAAAALGV
HHHHHHHCCCEEEEECCCCCCCCCEEEECCCCHHHHHHHCCCCCCHHCCCHHHHHHHHHH
VAWAKKK
HHHHCCC
>Mature Secondary Structure 
AQFDAIVVGGGHNGLTCACYLQKAGIKTLVIERRAIVGGAVCTETMFGGYKMDVGSSAH
CCEEEEEEECCCCCCEEEEEEECCCCEEEEEEHHHHHCHHHHHHHHCCCEEECCCCCCE
IMIHLTPVVRELELHKFGLEYIDMDPFAWYPLPDGSGAIEFWRDLDKTCASIEKISPKDA
EEEEECHHHHHHHHHHHCCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHH
HAYRQFVALWGPLNEGVFDVFLKAPSPANLGRQMLTGQFKGEKGTHPLDILRRLFTSYGH
HHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
LINETFESEAMRAAMGWLAAQSGPPPHEIGTGDFAGWHAMLHESGAKHPRGGSGMLTQAM
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHH
AARFKSDGGTLLLDAPVERIVVQNGVVHGVQLTSGETYTAPTVISNAHVQTTLLKLVEPE
HHHHCCCCCEEEECCCHHHHHHHCCCEEEEEEECCCCEECCCEECCCHHHHHHHHHHCHH
QLPNGLVERVGRIRVGNGFGMAVRCAADELPDYLAAPSGGRPHPSHHGLQLLCPSIDYLN
HCCCHHHHHHCEEEECCCCCEEEEECHHHCCHHHCCCCCCCCCCCCCCCEEECCCHHHHH
RAVSDYDRGVPATDPAVIAMTFSAIDPDVAPKGKHTLFLWGQYHPYQLSNGEDWDSIAER
HHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEEECCCCEECCCCCCHHHHHHH
EADKLLEVVYRYAPNMRGKISNRYVQTPLTLERTFGMLRGNVMHVEMSFDQMFAFRPLPE
HHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHHCCCEEEEEECHHHHHHCCCCCC
LSEYRVAGIKGLYLTGASTHPGGGVFAASGYNTAQTVLKDQQPSRQWVGWTLGAAAALGV
HHHHHHHCCCEEEEECCCCCCCCCEEEECCCCHHHHHHHCCCCCCHHCCCHHHHHHHHHH
VAWAKKK
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2263648 [H]