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The map label for this gene is narX [C]

Identifier: 159900292

GI number: 159900292

Start: 4745007

End: 4746653

Strand: Direct

Name: narX [C]

Synonym: Haur_3775

Alternate gene names: 159900292

Gene position: 4745007-4746653 (Clockwise)

Preceding gene: 159900291

Following gene: 159900293

Centisome position: 74.76

GC content: 50.27

Gene sequence:

>1647_bases
ATGCCATCAATAACTCTCGATGCTCAACGCTGGCAAACATTCAGTCAGTTGCTCACGGCAACCGCCTACCAAAACCCACA
GGATCTGCTTGATTCGTTTTTGCAACGTTTAATCGAGTTTTGGCCGGCCCAAGCAGGGGCATTGCTCTATATTGATCCAT
TAAATGTGCCGTTTTCGCTGGAGCATGGCGAATTGCCTGCCGATGGTCACGAAATGATCGAGCAAGCTCGTTCGGTATTC
GAGCGCACAACTGGCGGCGAGCAAGATTTAGGGGTCTATGGGATTAACGATGAGCTAGCCTTGGTGGAATTAACTCTGCG
TTCTGGTGATGATGAAGTTGGCCTGTTGCACCTGATTGTTTCTGCCGACCGCGTATCACCTGAGAATGAGGGCGAATTGG
CCTTGCTTTTGGTGGGCGTGGCTGGTGGAGCCGCCGATCGAGTGGCCTTGCTCAACACGACGCGCAGCGAACTTGATGAG
ATGAATTTGCTCTATCAAGTCAGCCAATCGATTGCCAGTGATATTGATTTGCGCAGCCTTTTGCGCACGATTATTGAAAA
AGTTACCCAAATTGTCGATAGCGAAAGCGCTTCGTTGCTGTTGGTCGATGAAGTGCATAAAGAGCTGTATTTTGAAACGC
CTTCGAACAATAGCCAAGAATTGCGCTCTTATCGCATGCCAATGGATCAAGGCTTCGCTGGCTGGGTTGTCACCCATGGC
CAAGGCTTGATTGTTGATGATCCACAAAATGATGCGCGGTTCTATCGCCAAGTTGATAGCGATATTTCGCATCAAACCCG
CAATATTCTGACCGTGCCAGTGCGTTCACGCGAACGGACAGTTGGGGTAATTCAGGCAGTCAATAAGCGTAATGGCCCGT
TTACCGAGCACGATTTGCGCACGCTCTCGATGCTCGCCAACCAAGCGGCGATCTCGATTGAAAATGCCAATCTTTACACC
AAACTCAAAGAAGAACGCGATCGTTTGATTCGCAAAGAAGAAGAAGTGCGTCACCAAATCAATCGCGATCTGCACGATGG
GCCAACCCAATCGGTCGCAGCGATTGCCATGAACATCGAGTTCATCAAAAAATTGATGCAGGCCATGCCTGAGCGCGTCG
AAGATGAGCTTAATTCATTAGCGGCCTTGGTCAAAAAAACCTACCAAGAATTGCGGACGTTGCTATTTGAGTTACGCCCG
TTGGGTCTCGAAACCCAAGGCTTGGTGGCAACTCTACACGAATACGCCAACAAATTCCGCGATCCATCGGGGATGCAAGT
GCGCTTTACGCCTGGCAACTTTATTGGTCGTTTGGCCCCACAAACTGCCGCCGCCACCTTTATGATTATCCAAGAGGCGG
TCAATAATGCCCGCAAACATGCCAAAGCCTCGATGGTCTGGATTGAGCTTTTTCAAGATAGTGAACGCCAAATGCTGACT
GCGGTTGTGCGTGATAGTGGGATTGGCTTTGATCTTAAGAGCATCACCACGTCGTATGAGGAGCGTGGCTCGTTTGGGTT
GTTGAATATGGGCGAACGGGCAACCCTCGCGGGTGGCGCTTGCGAAATTCGCTCGTCGGCAGGCGAAGGAACCCAAATTA
TCATTCGAGTGCCGACCTTGGTCGAAGAAGCCGAAGATTTTGCGTAA

Upstream 100 bases:

>100_bases
ATCATTGCAAAACTATGCTAAAACTGATCAACCATGATCAAGGCTTGACGCTGTTGCATGGCTAGGGTAGATTGAGTTGA
TACTGCAAGGAGGCTCGGTA

Downstream 100 bases:

>100_bases
CGTGCCAATCAAGGCCTGAACATAGAGCACCCTTTTGTCTGGTGGCAAGGACAAGAGGGTGCTCTTTAATGCCTATTGCG
CCTGAGGAAAGCCATGTATT

Product: GAF sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MPSITLDAQRWQTFSQLLTATAYQNPQDLLDSFLQRLIEFWPAQAGALLYIDPLNVPFSLEHGELPADGHEMIEQARSVF
ERTTGGEQDLGVYGINDELALVELTLRSGDDEVGLLHLIVSADRVSPENEGELALLLVGVAGGAADRVALLNTTRSELDE
MNLLYQVSQSIASDIDLRSLLRTIIEKVTQIVDSESASLLLVDEVHKELYFETPSNNSQELRSYRMPMDQGFAGWVVTHG
QGLIVDDPQNDARFYRQVDSDISHQTRNILTVPVRSRERTVGVIQAVNKRNGPFTEHDLRTLSMLANQAAISIENANLYT
KLKEERDRLIRKEEEVRHQINRDLHDGPTQSVAAIAMNIEFIKKLMQAMPERVEDELNSLAALVKKTYQELRTLLFELRP
LGLETQGLVATLHEYANKFRDPSGMQVRFTPGNFIGRLAPQTAAATFMIIQEAVNNARKHAKASMVWIELFQDSERQMLT
AVVRDSGIGFDLKSITTSYEERGSFGLLNMGERATLAGGACEIRSSAGEGTQIIIRVPTLVEEAEDFA

Sequences:

>Translated_548_residues
MPSITLDAQRWQTFSQLLTATAYQNPQDLLDSFLQRLIEFWPAQAGALLYIDPLNVPFSLEHGELPADGHEMIEQARSVF
ERTTGGEQDLGVYGINDELALVELTLRSGDDEVGLLHLIVSADRVSPENEGELALLLVGVAGGAADRVALLNTTRSELDE
MNLLYQVSQSIASDIDLRSLLRTIIEKVTQIVDSESASLLLVDEVHKELYFETPSNNSQELRSYRMPMDQGFAGWVVTHG
QGLIVDDPQNDARFYRQVDSDISHQTRNILTVPVRSRERTVGVIQAVNKRNGPFTEHDLRTLSMLANQAAISIENANLYT
KLKEERDRLIRKEEEVRHQINRDLHDGPTQSVAAIAMNIEFIKKLMQAMPERVEDELNSLAALVKKTYQELRTLLFELRP
LGLETQGLVATLHEYANKFRDPSGMQVRFTPGNFIGRLAPQTAAATFMIIQEAVNNARKHAKASMVWIELFQDSERQMLT
AVVRDSGIGFDLKSITTSYEERGSFGLLNMGERATLAGGACEIRSSAGEGTQIIIRVPTLVEEAEDFA
>Mature_547_residues
PSITLDAQRWQTFSQLLTATAYQNPQDLLDSFLQRLIEFWPAQAGALLYIDPLNVPFSLEHGELPADGHEMIEQARSVFE
RTTGGEQDLGVYGINDELALVELTLRSGDDEVGLLHLIVSADRVSPENEGELALLLVGVAGGAADRVALLNTTRSELDEM
NLLYQVSQSIASDIDLRSLLRTIIEKVTQIVDSESASLLLVDEVHKELYFETPSNNSQELRSYRMPMDQGFAGWVVTHGQ
GLIVDDPQNDARFYRQVDSDISHQTRNILTVPVRSRERTVGVIQAVNKRNGPFTEHDLRTLSMLANQAAISIENANLYTK
LKEERDRLIRKEEEVRHQINRDLHDGPTQSVAAIAMNIEFIKKLMQAMPERVEDELNSLAALVKKTYQELRTLLFELRPL
GLETQGLVATLHEYANKFRDPSGMQVRFTPGNFIGRLAPQTAAATFMIIQEAVNNARKHAKASMVWIELFQDSERQMLTA
VVRDSGIGFDLKSITTSYEERGSFGLLNMGERATLAGGACEIRSSAGEGTQIIIRVPTLVEEAEDFA

Specific function: Acts As A Sensor For Nitrate/Nitrite And Transduces Signal Of Nitrate Availability To The Narl Protein And Of Both Nitrate/Nitrite To The Narp Protein. Narx Probably Activates Narl And Narp By Phosphorylation In The Presence Of Nitrate. Narx Also Plays A

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Homo sapiens, GI4505657, Length=224, Percent_Identity=32.1428571428571, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI219802706, Length=224, Percent_Identity=32.1428571428571, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI226246591, Length=224, Percent_Identity=32.1428571428571, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI194595488, Length=243, Percent_Identity=28.8065843621399, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI116536085, Length=186, Percent_Identity=29.0322580645161, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI5729972, Length=243, Percent_Identity=28.8065843621399, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI61744430, Length=194, Percent_Identity=28.3505154639175, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI61744432, Length=194, Percent_Identity=28.3505154639175, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI61744435, Length=194, Percent_Identity=28.3505154639175, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1787474, Length=218, Percent_Identity=29.8165137614679, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193202333, Length=173, Percent_Identity=31.2138728323699, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI161076955, Length=188, Percent_Identity=28.1914893617021, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI161076953, Length=188, Percent_Identity=28.1914893617021, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR011712
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 61178; Mature: 61047

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSITLDAQRWQTFSQLLTATAYQNPQDLLDSFLQRLIEFWPAQAGALLYIDPLNVPFSL
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEE
EHGELPADGHEMIEQARSVFERTTGGEQDLGVYGINDELALVELTLRSGDDEVGLLHLIV
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEEEECCCCCCHHHEEEEE
SADRVSPENEGELALLLVGVAGGAADRVALLNTTRSELDEMNLLYQVSQSIASDIDLRSL
EHHCCCCCCCCCEEEEEEEECCCCCCCEEEHHCCHHHHHHHHHHHHHHHHHHCCCCHHHH
LRTIIEKVTQIVDSESASLLLVDEVHKELYFETPSNNSQELRSYRMPMDQGFAGWVVTHG
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHEEECCCCCHHHHHHHCCCCCCCCCCEEEECC
QGLIVDDPQNDARFYRQVDSDISHQTRNILTVPVRSRERTVGVIQAVNKRNGPFTEHDLR
CEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHH
TLSMLANQAAISIENANLYTKLKEERDRLIRKEEEVRHQINRDLHDGPTQSVAAIAMNIE
HHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
FIKKLMQAMPERVEDELNSLAALVKKTYQELRTLLFELRPLGLETQGLVATLHEYANKFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
DPSGMQVRFTPGNFIGRLAPQTAAATFMIIQEAVNNARKHAKASMVWIELFQDSERQMLT
CCCCCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
AVVRDSGIGFDLKSITTSYEERGSFGLLNMGERATLAGGACEIRSSAGEGTQIIIRVPTL
HHHHCCCCCCCHHHHHHHHHHCCCCCEEECCCCCEECCCCEEECCCCCCCCEEEEECCHH
VEEAEDFA
HHHHHCCC
>Mature Secondary Structure 
PSITLDAQRWQTFSQLLTATAYQNPQDLLDSFLQRLIEFWPAQAGALLYIDPLNVPFSL
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEE
EHGELPADGHEMIEQARSVFERTTGGEQDLGVYGINDELALVELTLRSGDDEVGLLHLIV
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEEEECCCCCCHHHEEEEE
SADRVSPENEGELALLLVGVAGGAADRVALLNTTRSELDEMNLLYQVSQSIASDIDLRSL
EHHCCCCCCCCCEEEEEEEECCCCCCCEEEHHCCHHHHHHHHHHHHHHHHHHCCCCHHHH
LRTIIEKVTQIVDSESASLLLVDEVHKELYFETPSNNSQELRSYRMPMDQGFAGWVVTHG
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHEEECCCCCHHHHHHHCCCCCCCCCCEEEECC
QGLIVDDPQNDARFYRQVDSDISHQTRNILTVPVRSRERTVGVIQAVNKRNGPFTEHDLR
CEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHH
TLSMLANQAAISIENANLYTKLKEERDRLIRKEEEVRHQINRDLHDGPTQSVAAIAMNIE
HHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
FIKKLMQAMPERVEDELNSLAALVKKTYQELRTLLFELRPLGLETQGLVATLHEYANKFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
DPSGMQVRFTPGNFIGRLAPQTAAATFMIIQEAVNNARKHAKASMVWIELFQDSERQMLT
CCCCCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
AVVRDSGIGFDLKSITTSYEERGSFGLLNMGERATLAGGACEIRSSAGEGTQIIIRVPTL
HHHHCCCCCCCHHHHHHHHHHCCCCCEEECCCCCEECCCCEEECCCCCCCCEEEEECCHH
VEEAEDFA
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with a nitrogenous group as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8661927 [H]