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The map label for this gene is pcrA [H]

Identifier: 159900168

GI number: 159900168

Start: 4590889

End: 4592814

Strand: Reverse

Name: pcrA [H]

Synonym: Haur_3651

Alternate gene names: 159900168

Gene position: 4592814-4590889 (Counterclockwise)

Preceding gene: 159900169

Following gene: 159900167

Centisome position: 72.37

GC content: 53.17

Gene sequence:

>1926_bases
ATGTTTGATACACTCAATAGCGAACAACGGGCGGCGGTAATGGCGCAGCTTGGGCCAGTTTTGGTCAAGGCTGGCGCGGG
CAGCGGTAAAACTCGCGTGCTGACCTACCGCATCGCCTATTTAATCGAGCAGGGCGCTAGCTCCGATTCGATTGTTTCGG
TGACCTTCACCAACAAAGCCGCCAGCGAACTGCGTACCCGCTTGCGCGATCTTTTGGGCAAGCGTAGCCGTGGCCTGACT
GCCGGAACCTTCCACGCGATTTGTGGCAAATTGCTGCGCCAACATATTAATGGACGAATTCGCAATTACACTGCCAACTT
TACAATTTACGCTGGCGATGAGCAATTGCAACTGGTGCAACAAGCCATGGATGGCTATACCGGACGCATGCCGCACGATC
TTGAAGCACCGCAAGTGCTCAATTTGATTTCGCGCTTCAAAAGCCGCATGCAACCACCAACCTTAGCTCGGCAGATGGCT
AGTGATCCGGTCAGTCAATATGCAGCAGCGATTTATCGCACCTATCAACGTCAGCTTGAGCGCTCGAATGCTGTTGATTT
CGATGATATGATCGTGATGACCTACAAGCTGTTGTTTGAGCATCACGATGTGCTCGATGAAGTTCAATCGCGCTGGGCGC
ATGTGTTGGTCGATGAATATCAAGATACCGATTCGGCCCAATATGCCTTGCTCGAGTTACTTTCACGGCCAGTTGCTCAG
CGCCCACGCTCATTGTTTGCGGTTGGCGATGCCCAACAATCGATCTATGGTTTTCGCAACGCCGATTACACGATCATCAA
TCGCTTCACCCGCGATTTCCCTGAAGCCCAAGTGGTTGAGTTGTTGACCAATTATCGTTCGCGCCAAGAGATTCTTGATG
CGGCCTATGCCGTGATGCGCCATTCGGTCGCTGTGCCAGCCTTGACCTTGAAAGCTGCGCGTCGTTCGCCGCCAGTGCCA
GCCTTGGTGATCAACGAGGCTACTGATGATCGCGCCGAAGCCGATGCGATTGCCAAATCAATTGGTAATTTGCTGAGCAC
AGGTCGTCGCAGCAAAGATATTGCGATTTTGTATCGTTCGCGGCATATGAGCCGTGGCCTAGAAACGGCGCTGCGCCAAG
CACGGATTCCCTATTCGCTCAAGGGTCAAGCGGGGTTTTACGATCGGCGGGTGATTCGCGATGCTTTGGCCTTTTTGCGG
ATTATTGCTAATCCCAGCGATAGCCTGAGCATGAATCGGATTATCAATGTGCCAGCGCGTGGCATTGGCGCTAGCACAAT
CGCCCATCTCACCAGCAAAGCTGCTGCACTGGAACTACCGCTCGGTGAAGCCTTGTTGAAGCGTGAAGCATGGGAAGGCT
TGAGTGATCGAGCCAGCCAAATGGTCAGCGATTGGGCACGCAAAGTCTATCGTTGGCGCAAATTGGCTAGCGGCAGCTAC
CCACCCGAGGGCTTGTTGCAAACGGTGCTGCAAGAAAGTGGCTATCAATCCATGATCGAAAAAGACTGGAACGACCCTGA
GCGCAGTGATGCCCTGGCCCACCTTGAAGAATTACGGGTTGCTGCTGGCGAACATACCAGCCTCGCAGCCTTTTTGCAGG
AAATTGCCCTGCTGACCAACGTTGAAGACAAAGATGAGCGTGATGCTGTTCAATTGCTGACCATCCACGGAGCCAAAGGC
TTGGAATGGCCAATTGTCTACGTGGCGGGCTTGGAAGAAGGTACATTGCCCCACGAACGTTCGTTGGTCGAAGCAGGCGG
GGTGGAAGAAGAGCGGCGTTTGTGCTATGTGGCCTTGACCCGCGCAGGTGAACAACTCTATCTTTCGCATGCCAAAAAAC
GCCAACGCAACCAACGTAATCCATCGCGCTTCCTTGATGATATTTTGGTTTATGGCCGTGAACGCGCCAAAGCCAAGGCT
TTCTAA

Upstream 100 bases:

>100_bases
TTTGGTACTTTAATCAATTAAAGTAATCCTGCGATTTTGATGATACCATTTATATTCGATTTTTTGACTTTTGACTTCTG
ATTTTTGCCTTTAAAAAACT

Downstream 100 bases:

>100_bases
CCGTTCGTTAACCTTTAGGTAAACTTTTGAGCCTACACTCAGAGTGTTAGGATTTTTGCAGCGTAGGAGTGACCCATGAA
AGAGTTAATTGCCCAACTTG

Product: UvrD/REP helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 641; Mature: 641

Protein sequence:

>641_residues
MFDTLNSEQRAAVMAQLGPVLVKAGAGSGKTRVLTYRIAYLIEQGASSDSIVSVTFTNKAASELRTRLRDLLGKRSRGLT
AGTFHAICGKLLRQHINGRIRNYTANFTIYAGDEQLQLVQQAMDGYTGRMPHDLEAPQVLNLISRFKSRMQPPTLARQMA
SDPVSQYAAAIYRTYQRQLERSNAVDFDDMIVMTYKLLFEHHDVLDEVQSRWAHVLVDEYQDTDSAQYALLELLSRPVAQ
RPRSLFAVGDAQQSIYGFRNADYTIINRFTRDFPEAQVVELLTNYRSRQEILDAAYAVMRHSVAVPALTLKAARRSPPVP
ALVINEATDDRAEADAIAKSIGNLLSTGRRSKDIAILYRSRHMSRGLETALRQARIPYSLKGQAGFYDRRVIRDALAFLR
IIANPSDSLSMNRIINVPARGIGASTIAHLTSKAAALELPLGEALLKREAWEGLSDRASQMVSDWARKVYRWRKLASGSY
PPEGLLQTVLQESGYQSMIEKDWNDPERSDALAHLEELRVAAGEHTSLAAFLQEIALLTNVEDKDERDAVQLLTIHGAKG
LEWPIVYVAGLEEGTLPHERSLVEAGGVEEERRLCYVALTRAGEQLYLSHAKKRQRNQRNPSRFLDDILVYGRERAKAKA
F

Sequences:

>Translated_641_residues
MFDTLNSEQRAAVMAQLGPVLVKAGAGSGKTRVLTYRIAYLIEQGASSDSIVSVTFTNKAASELRTRLRDLLGKRSRGLT
AGTFHAICGKLLRQHINGRIRNYTANFTIYAGDEQLQLVQQAMDGYTGRMPHDLEAPQVLNLISRFKSRMQPPTLARQMA
SDPVSQYAAAIYRTYQRQLERSNAVDFDDMIVMTYKLLFEHHDVLDEVQSRWAHVLVDEYQDTDSAQYALLELLSRPVAQ
RPRSLFAVGDAQQSIYGFRNADYTIINRFTRDFPEAQVVELLTNYRSRQEILDAAYAVMRHSVAVPALTLKAARRSPPVP
ALVINEATDDRAEADAIAKSIGNLLSTGRRSKDIAILYRSRHMSRGLETALRQARIPYSLKGQAGFYDRRVIRDALAFLR
IIANPSDSLSMNRIINVPARGIGASTIAHLTSKAAALELPLGEALLKREAWEGLSDRASQMVSDWARKVYRWRKLASGSY
PPEGLLQTVLQESGYQSMIEKDWNDPERSDALAHLEELRVAAGEHTSLAAFLQEIALLTNVEDKDERDAVQLLTIHGAKG
LEWPIVYVAGLEEGTLPHERSLVEAGGVEEERRLCYVALTRAGEQLYLSHAKKRQRNQRNPSRFLDDILVYGRERAKAKA
F
>Mature_641_residues
MFDTLNSEQRAAVMAQLGPVLVKAGAGSGKTRVLTYRIAYLIEQGASSDSIVSVTFTNKAASELRTRLRDLLGKRSRGLT
AGTFHAICGKLLRQHINGRIRNYTANFTIYAGDEQLQLVQQAMDGYTGRMPHDLEAPQVLNLISRFKSRMQPPTLARQMA
SDPVSQYAAAIYRTYQRQLERSNAVDFDDMIVMTYKLLFEHHDVLDEVQSRWAHVLVDEYQDTDSAQYALLELLSRPVAQ
RPRSLFAVGDAQQSIYGFRNADYTIINRFTRDFPEAQVVELLTNYRSRQEILDAAYAVMRHSVAVPALTLKAARRSPPVP
ALVINEATDDRAEADAIAKSIGNLLSTGRRSKDIAILYRSRHMSRGLETALRQARIPYSLKGQAGFYDRRVIRDALAFLR
IIANPSDSLSMNRIINVPARGIGASTIAHLTSKAAALELPLGEALLKREAWEGLSDRASQMVSDWARKVYRWRKLASGSY
PPEGLLQTVLQESGYQSMIEKDWNDPERSDALAHLEELRVAAGEHTSLAAFLQEIALLTNVEDKDERDAVQLLTIHGAKG
LEWPIVYVAGLEEGTLPHERSLVEAGGVEEERRLCYVALTRAGEQLYLSHAKKRQRNQRNPSRFLDDILVYGRERAKAKA
F

Specific function: Essential helicase [H]

COG id: COG0210

COG function: function code L; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367296, Length=653, Percent_Identity=35.375191424196, Blast_Score=331, Evalue=8e-92,
Organism=Escherichia coli, GI48994965, Length=662, Percent_Identity=33.5347432024169, Blast_Score=291, Evalue=7e-80,
Organism=Escherichia coli, GI1787196, Length=325, Percent_Identity=29.8461538461538, Blast_Score=105, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6322369, Length=747, Percent_Identity=27.8447121820616, Blast_Score=197, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6324477, Length=691, Percent_Identity=22.575976845152, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: 3000 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005751
- InterPro:   IPR013986
- InterPro:   IPR014017
- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 71884; Mature: 71884

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDTLNSEQRAAVMAQLGPVLVKAGAGSGKTRVLTYRIAYLIEQGASSDSIVSVTFTNKA
CCCCCCCHHHHHHHHHHCHHEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCHH
ASELRTRLRDLLGKRSRGLTAGTFHAICGKLLRQHINGRIRNYTANFTIYAGDEQLQLVQ
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCHHHHHHH
QAMDGYTGRMPHDLEAPQVLNLISRFKSRMQPPTLARQMASDPVSQYAAAIYRTYQRQLE
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RSNAVDFDDMIVMTYKLLFEHHDVLDEVQSRWAHVLVDEYQDTDSAQYALLELLSRPVAQ
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHH
RPRSLFAVGDAQQSIYGFRNADYTIINRFTRDFPEAQVVELLTNYRSRQEILDAAYAVMR
CCCCEEEECCHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HSVAVPALTLKAARRSPPVPALVINEATDDRAEADAIAKSIGNLLSTGRRSKDIAILYRS
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHH
RHMSRGLETALRQARIPYSLKGQAGFYDRRVIRDALAFLRIIANPSDSLSMNRIINVPAR
HHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEECCCC
GIGASTIAHLTSKAAALELPLGEALLKREAWEGLSDRASQMVSDWARKVYRWRKLASGSY
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
PPEGLLQTVLQESGYQSMIEKDWNDPERSDALAHLEELRVAAGEHTSLAAFLQEIALLTN
CHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
VEDKDERDAVQLLTIHGAKGLEWPIVYVAGLEEGTLPHERSLVEAGGVEEERRLCYVALT
CCCCCCHHHHHEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHH
RAGEQLYLSHAKKRQRNQRNPSRFLDDILVYGRERAKAKAF
HCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHCCCC
>Mature Secondary Structure
MFDTLNSEQRAAVMAQLGPVLVKAGAGSGKTRVLTYRIAYLIEQGASSDSIVSVTFTNKA
CCCCCCCHHHHHHHHHHCHHEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCHH
ASELRTRLRDLLGKRSRGLTAGTFHAICGKLLRQHINGRIRNYTANFTIYAGDEQLQLVQ
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCHHHHHHH
QAMDGYTGRMPHDLEAPQVLNLISRFKSRMQPPTLARQMASDPVSQYAAAIYRTYQRQLE
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RSNAVDFDDMIVMTYKLLFEHHDVLDEVQSRWAHVLVDEYQDTDSAQYALLELLSRPVAQ
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHH
RPRSLFAVGDAQQSIYGFRNADYTIINRFTRDFPEAQVVELLTNYRSRQEILDAAYAVMR
CCCCEEEECCHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HSVAVPALTLKAARRSPPVPALVINEATDDRAEADAIAKSIGNLLSTGRRSKDIAILYRS
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHH
RHMSRGLETALRQARIPYSLKGQAGFYDRRVIRDALAFLRIIANPSDSLSMNRIINVPAR
HHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEECCCC
GIGASTIAHLTSKAAALELPLGEALLKREAWEGLSDRASQMVSDWARKVYRWRKLASGSY
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
PPEGLLQTVLQESGYQSMIEKDWNDPERSDALAHLEELRVAAGEHTSLAAFLQEIALLTN
CHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
VEDKDERDAVQLLTIHGAKGLEWPIVYVAGLEEGTLPHERSLVEAGGVEEERRLCYVALT
CCCCCCHHHHHEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHH
RAGEQLYLSHAKKRQRNQRNPSRFLDDILVYGRERAKAKAF
HCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA