Click here to switch to the map view.

The map label for this gene is rsbRB [H]

Identifier: 159900166

GI number: 159900166

Start: 4589394

End: 4590479

Strand: Reverse

Name: rsbRB [H]

Synonym: Haur_3649

Alternate gene names: 159900166

Gene position: 4590479-4589394 (Counterclockwise)

Preceding gene: 159900167

Following gene: 159900162

Centisome position: 72.33

GC content: 43.37

Gene sequence:

>1086_bases
ATGCAAAGCACTCGCATTGTTGACCCTGATCAACTGCCTGATCATCTGCGTTTAGGCCGTTATCTGGGCTTAACTGCCAT
CGCAATTTACCTTGGACTATTTACCGGGGCTGGCCTGACTGTGATGATTCCCGATGCCTCGGATTTCATCATGCAATCGA
AAATTCCGCTTAGCGGTTTTGCGGTGCTGATACAAGGCTTATTTTTCATTGCCGCTCGCTTTTTTGCTCGCCGGAATGAG
ATCAATCGTAGTATTTACCTTATGATGCTTGGCTGTACCTTATTGCCAATGATCATTACCTTTTTCAATCCAATTGAATG
GCCACTCAGTGTTTTGTATGTTTTTTTGATGTTGATTATTGCGGTTCAGTTTGTTAATAGCTATAACCTCAAACGGATTA
GTATTGTGGCTTGGCTTTCAATTATTATCATTTTGTTTTTTGGCTTTATCTTCAATGATCAATATAATTATCCAAAAATC
AATGTGCTGTTGATTATGATTACCTCTGGTGCACCAATCGTCACCATGATTATTTCAATTTTGTTTAGTTTTCATCGACG
CTTGAATTTGACCTTGCGTGAAGTCAAACGAATTAATTATTCGCTAGAAGAATCGCGCGATTCGTTAGAACAACAAGTTG
AGCAACGCACCCAGCAATTGCAACAGACGCTCGGCGAATTACAGCAACGTAATCAAGAGCAAGCAGCCTATGTTGCCCAA
ATTGAGCAACAACGCCAAACAATTCGCGAATTAAGCGTGCCAGTGCTGCCAGTTAGCCGCGATACCTTGGTGTTGCCAAT
TGTCGGCACTGTGGAAAATGAACGCTTACGCGATTTACAGGCGATTGCCTTAGGCGAAATTCAACGTCGTCGTGCTCAAC
GCTTGTTGCTCGATGTAACGGGGCTTTCATGGTTTGATAATGATGTGGCTGCTGGATTACTGCGTTTGATTGATGCTGCC
CAATTGCTGGGAGCCAAGGTTGCCCTAATTGGCGTGCGGCCAGAGGTAGCTCAAGCTTTGGTCAATTTGGGGATTGTTTT
TGATAATGTGGCGATCTATCGCGATTTACAATCGGCATTGAACTAG

Upstream 100 bases:

>100_bases
TTGATCAAGAGCAGCCAAGCTTGGCTGCTCTTTTGTTGTATTAGCATATGTCGAAAATTTGATACAATAGCAACACTGTG
TGGCAAAAGGAACGTGATCT

Downstream 100 bases:

>100_bases
GGAAATGGCCGAATTGCCCCAACATAGCGGCTGCTCCAATAGCTATTGGATAAATCGGAAACGCGAATGCCTAAACTCTC
GGAGAGCGCCTGAATCACTT

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRB [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MQSTRIVDPDQLPDHLRLGRYLGLTAIAIYLGLFTGAGLTVMIPDASDFIMQSKIPLSGFAVLIQGLFFIAARFFARRNE
INRSIYLMMLGCTLLPMIITFFNPIEWPLSVLYVFLMLIIAVQFVNSYNLKRISIVAWLSIIIILFFGFIFNDQYNYPKI
NVLLIMITSGAPIVTMIISILFSFHRRLNLTLREVKRINYSLEESRDSLEQQVEQRTQQLQQTLGELQQRNQEQAAYVAQ
IEQQRQTIRELSVPVLPVSRDTLVLPIVGTVENERLRDLQAIALGEIQRRRAQRLLLDVTGLSWFDNDVAAGLLRLIDAA
QLLGAKVALIGVRPEVAQALVNLGIVFDNVAIYRDLQSALN

Sequences:

>Translated_361_residues
MQSTRIVDPDQLPDHLRLGRYLGLTAIAIYLGLFTGAGLTVMIPDASDFIMQSKIPLSGFAVLIQGLFFIAARFFARRNE
INRSIYLMMLGCTLLPMIITFFNPIEWPLSVLYVFLMLIIAVQFVNSYNLKRISIVAWLSIIIILFFGFIFNDQYNYPKI
NVLLIMITSGAPIVTMIISILFSFHRRLNLTLREVKRINYSLEESRDSLEQQVEQRTQQLQQTLGELQQRNQEQAAYVAQ
IEQQRQTIRELSVPVLPVSRDTLVLPIVGTVENERLRDLQAIALGEIQRRRAQRLLLDVTGLSWFDNDVAAGLLRLIDAA
QLLGAKVALIGVRPEVAQALVNLGIVFDNVAIYRDLQSALN
>Mature_361_residues
MQSTRIVDPDQLPDHLRLGRYLGLTAIAIYLGLFTGAGLTVMIPDASDFIMQSKIPLSGFAVLIQGLFFIAARFFARRNE
INRSIYLMMLGCTLLPMIITFFNPIEWPLSVLYVFLMLIIAVQFVNSYNLKRISIVAWLSIIIILFFGFIFNDQYNYPKI
NVLLIMITSGAPIVTMIISILFSFHRRLNLTLREVKRINYSLEESRDSLEQQVEQRTQQLQQTLGELQQRNQEQAAYVAQ
IEQQRQTIRELSVPVLPVSRDTLVLPIVGTVENERLRDLQAIALGEIQRRRAQRLLLDVTGLSWFDNDVAAGLLRLIDAA
QLLGAKVALIGVRPEVAQALVNLGIVFDNVAIYRDLQSALN

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 40950; Mature: 40950

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSTRIVDPDQLPDHLRLGRYLGLTAIAIYLGLFTGAGLTVMIPDASDFIMQSKIPLSGF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCHHHH
AVLIQGLFFIAARFFARRNEINRSIYLMMLGCTLLPMIITFFNPIEWPLSVLYVFLMLII
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AVQFVNSYNLKRISIVAWLSIIIILFFGFIFNDQYNYPKINVLLIMITSGAPIVTMIISI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHH
LFSFHRRLNLTLREVKRINYSLEESRDSLEQQVEQRTQQLQQTLGELQQRNQEQAAYVAQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
IEQQRQTIRELSVPVLPVSRDTLVLPIVGTVENERLRDLQAIALGEIQRRRAQRLLLDVT
HHHHHHHHHHCCCCCEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLSWFDNDVAAGLLRLIDAAQLLGAKVALIGVRPEVAQALVNLGIVFDNVAIYRDLQSAL
CCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHC
N
C
>Mature Secondary Structure
MQSTRIVDPDQLPDHLRLGRYLGLTAIAIYLGLFTGAGLTVMIPDASDFIMQSKIPLSGF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCHHHH
AVLIQGLFFIAARFFARRNEINRSIYLMMLGCTLLPMIITFFNPIEWPLSVLYVFLMLII
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AVQFVNSYNLKRISIVAWLSIIIILFFGFIFNDQYNYPKINVLLIMITSGAPIVTMIISI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHH
LFSFHRRLNLTLREVKRINYSLEESRDSLEQQVEQRTQQLQQTLGELQQRNQEQAAYVAQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
IEQQRQTIRELSVPVLPVSRDTLVLPIVGTVENERLRDLQAIALGEIQRRRAQRLLLDVT
HHHHHHHHHHCCCCCEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLSWFDNDVAAGLLRLIDAAQLLGAKVALIGVRPEVAQALVNLGIVFDNVAIYRDLQSAL
CCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHC
N
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11157946 [H]