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The map label for this gene is rsbRA [H]

Identifier: 159900126

GI number: 159900126

Start: 4536729

End: 4537964

Strand: Direct

Name: rsbRA [H]

Synonym: Haur_3609

Alternate gene names: 159900126

Gene position: 4536729-4537964 (Clockwise)

Preceding gene: 159900125

Following gene: 159900127

Centisome position: 71.48

GC content: 49.76

Gene sequence:

>1236_bases
ATGCGTTCATCGATTCGTCAACGTTTTGGCTTAGGCCTGATCATTCTGGTGATGGTGGTGGGCAGTGCCAATATCATTGC
TCGCTGGTCACTAGGCAAGTATCGCACTGATGTCGAGGCGCTGATCGATCAAACGATTCCGCAACTCGATTCATTGTTGC
GGCTGCAAACCAGTGCCCAAGGCATCACCCAAAATACTCTCGCATTTTTGCAAACCAAAGATGATCAATATCTGCTTTCG
CGAACTGGTTGGGTGCGCGAAACTGAGCGTTTAATTGGAGTGATGGATGGCTTAACTGATGATACCAATCAGCCAGTTCA
AGCAGCCTATGTTGCCTTACGCCGATCAGTTCAATCAATTATTGAAGATACCCAAACCTTTATTGATCGCTCTGCCACCG
ACGATCCTCGCGTGATCGAACGCCGCTTCGACCAAGTGCGCGATTTGAATTTATCGTTCGATACGCGCTTCAAAACCTAC
CGCGATTTAGTCACCGAAGAAGGCGTTCAGCGCCGCGCTAATATCTCCAATAATCCATTGCGTTATATGAATGTGCTGGG
CGTGATTGGGGTGATTGCCCTGATTGGCATGACGATCTTATTTCATCATATGATCTTTAAGCCAATTCGCGCCTTACAAA
AAACGGCCCAAACTGTGGCTGCTGGCGATTATGCGCAACGGGCCGAAGTTAAACGCCTCGATGAAATTGGCGATGTGTTT
GTGGCCTTCAACCATCTACTCGATAGCATTAACAACGAGCAGCAAGCCTTACGCGATCAGGTTGAGCGGGTCGATCAAGC
TCGTCATGAGGCCGAAATTGCCCGTAGCGATGCCGCCGCTCAACTTGACACCATCCAAAATCAACGGGCAATTATTCGCT
CGATGAGTGTGCCGATTTTGCCTGTTGGCAAGCGCATGTTGGTTGTGCCATTAATCGGCGAACTTGGACCACAACGCCTC
AAAACCCTGCAAACCAATGTGCTTGGTCGGATCTCGACTGACCGCCCACGCTGGATTATTATCGATGTGACGGGTGTGCC
AGTAATCGACAATATGGTCAGCCAAGCCTTCTCAGAACTGATTGATAGTGTGCGACTCTTGGGCAGCGAACCAATGCTGG
TTGGCATTCGGCCCGAAGTTGCTCAAGCGCTAGTTACCACTGGCATGAATTTCAATAGTTTAGTGGTTGAGGCGACCTTG
CAAGCAGGCATCGCCTACGCCGAACGCCATAGCTAA

Upstream 100 bases:

>100_bases
TGCCCAAATGGTCTTGTAAGCCATTCTTGCAACGCTCAACAACGAATCAACAACAGCATAATCGCATGGATCATATCAAC
ACTATTTACACTGAGGCATT

Downstream 100 bases:

>100_bases
GTGATGCCCTCACACCCTTTGCCGCCCACTAGGCGAGGGGAACTACCACATCATGAAACTTGGAACTCCCCTCTCCCGCC
GCACTTTAAGGGCGGACAGG

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MRSSIRQRFGLGLIILVMVVGSANIIARWSLGKYRTDVEALIDQTIPQLDSLLRLQTSAQGITQNTLAFLQTKDDQYLLS
RTGWVRETERLIGVMDGLTDDTNQPVQAAYVALRRSVQSIIEDTQTFIDRSATDDPRVIERRFDQVRDLNLSFDTRFKTY
RDLVTEEGVQRRANISNNPLRYMNVLGVIGVIALIGMTILFHHMIFKPIRALQKTAQTVAAGDYAQRAEVKRLDEIGDVF
VAFNHLLDSINNEQQALRDQVERVDQARHEAEIARSDAAAQLDTIQNQRAIIRSMSVPILPVGKRMLVVPLIGELGPQRL
KTLQTNVLGRISTDRPRWIIIDVTGVPVIDNMVSQAFSELIDSVRLLGSEPMLVGIRPEVAQALVTTGMNFNSLVVEATL
QAGIAYAERHS

Sequences:

>Translated_411_residues
MRSSIRQRFGLGLIILVMVVGSANIIARWSLGKYRTDVEALIDQTIPQLDSLLRLQTSAQGITQNTLAFLQTKDDQYLLS
RTGWVRETERLIGVMDGLTDDTNQPVQAAYVALRRSVQSIIEDTQTFIDRSATDDPRVIERRFDQVRDLNLSFDTRFKTY
RDLVTEEGVQRRANISNNPLRYMNVLGVIGVIALIGMTILFHHMIFKPIRALQKTAQTVAAGDYAQRAEVKRLDEIGDVF
VAFNHLLDSINNEQQALRDQVERVDQARHEAEIARSDAAAQLDTIQNQRAIIRSMSVPILPVGKRMLVVPLIGELGPQRL
KTLQTNVLGRISTDRPRWIIIDVTGVPVIDNMVSQAFSELIDSVRLLGSEPMLVGIRPEVAQALVTTGMNFNSLVVEATL
QAGIAYAERHS
>Mature_411_residues
MRSSIRQRFGLGLIILVMVVGSANIIARWSLGKYRTDVEALIDQTIPQLDSLLRLQTSAQGITQNTLAFLQTKDDQYLLS
RTGWVRETERLIGVMDGLTDDTNQPVQAAYVALRRSVQSIIEDTQTFIDRSATDDPRVIERRFDQVRDLNLSFDTRFKTY
RDLVTEEGVQRRANISNNPLRYMNVLGVIGVIALIGMTILFHHMIFKPIRALQKTAQTVAAGDYAQRAEVKRLDEIGDVF
VAFNHLLDSINNEQQALRDQVERVDQARHEAEIARSDAAAQLDTIQNQRAIIRSMSVPILPVGKRMLVVPLIGELGPQRL
KTLQTNVLGRISTDRPRWIIIDVTGVPVIDNMVSQAFSELIDSVRLLGSEPMLVGIRPEVAQALVTTGMNFNSLVVEATL
QAGIAYAERHS

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 46053; Mature: 46053

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS50885 HAMP ; PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSSIRQRFGLGLIILVMVVGSANIIARWSLGKYRTDVEALIDQTIPQLDSLLRLQTSAQ
CCCHHHHHHCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GITQNTLAFLQTKDDQYLLSRTGWVRETERLIGVMDGLTDDTNQPVQAAYVALRRSVQSI
CCHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
IEDTQTFIDRSATDDPRVIERRFDQVRDLNLSFDTRFKTYRDLVTEEGVQRRANISNNPL
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
RYMNVLGVIGVIALIGMTILFHHMIFKPIRALQKTAQTVAAGDYAQRAEVKRLDEIGDVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
VAFNHLLDSINNEQQALRDQVERVDQARHEAEIARSDAAAQLDTIQNQRAIIRSMSVPIL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
PVGKRMLVVPLIGELGPQRLKTLQTNVLGRISTDRPRWIIIDVTGVPVIDNMVSQAFSEL
ECCCCEEEEHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHH
IDSVRLLGSEPMLVGIRPEVAQALVTTGMNFNSLVVEATLQAGIAYAERHS
HHHHHHHCCCCEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRSSIRQRFGLGLIILVMVVGSANIIARWSLGKYRTDVEALIDQTIPQLDSLLRLQTSAQ
CCCHHHHHHCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GITQNTLAFLQTKDDQYLLSRTGWVRETERLIGVMDGLTDDTNQPVQAAYVALRRSVQSI
CCHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
IEDTQTFIDRSATDDPRVIERRFDQVRDLNLSFDTRFKTYRDLVTEEGVQRRANISNNPL
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
RYMNVLGVIGVIALIGMTILFHHMIFKPIRALQKTAQTVAAGDYAQRAEVKRLDEIGDVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
VAFNHLLDSINNEQQALRDQVERVDQARHEAEIARSDAAAQLDTIQNQRAIIRSMSVPIL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
PVGKRMLVVPLIGELGPQRLKTLQTNVLGRISTDRPRWIIIDVTGVPVIDNMVSQAFSEL
ECCCCEEEEHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHH
IDSVRLLGSEPMLVGIRPEVAQALVTTGMNFNSLVVEATLQAGIAYAERHS
HHHHHHHCCCCEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]