| Definition | Herpetosiphon aurantiacus ATCC 23779 chromosome, complete genome. |
|---|---|
| Accession | NC_009972 |
| Length | 6,346,587 |
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The map label for this gene is cypB [H]
Identifier: 159900116
GI number: 159900116
Start: 4529565
End: 4530278
Strand: Direct
Name: cypB [H]
Synonym: Haur_3599
Alternate gene names: 159900116
Gene position: 4529565-4530278 (Clockwise)
Preceding gene: 159900115
Following gene: 159900120
Centisome position: 71.37
GC content: 51.82
Gene sequence:
>714_bases ATGCGACGAACAACCACGATTGCGCTGTTGGCGCTCGTATTAACCGCTTGTGGTTCAGCTGAATCAACCGCAATTCCAAC GATCGAAACGCGCCCAACCACCGCCCCAACTGCTGAAGTAGCCCCAACCGAGGCAAGCACTGGCCGACCAACCACTGCTC CTAGCGATGGTGGCAACACCAGCAGCCCTGGCATGCCGAAGCAATATGCCAGCGAGCCAGCCATGACGATTGACGTTAAC AAGCAATATATCGCGACCCTCAAAACCCAAAAAGGCGATATTGTGATTGAACTCAACGCCAAAAATGCTCCCCGCACGGT CAATAACTTTGTGTTTTTGGCTCGTGAAGGTTTCTACGATAACGTGACTTTCCATCGCGTGATTCCAGGCTTTATGGCTC AAGGTGGCGATCCAACTGGCACTGGGATGGGTGGCCCAGGCTATGAGTTTGTCAACGAATATGAAGATACCACCAGCAAT TTGCTCTTCGATAAAGCTGGGGTTTTGGCCATGGCCAACGCTGGCCCTAATACCAATGGTTCACAATTCTTCATTACCTT GGCTCCAGCCTTGCACTTGACCCCCGATGCCTATACAATCTTCGGCCAAGTAACTGCTGGTCAAGATGTCGTTGATCAGA TCACGCCTCGCGATCCAAACATGGGTGGCGCACCTGGCGATGCGATCTTGACGGTTACGATCGAAGAAAAATAG
Upstream 100 bases:
>100_bases TGCTCTTCGTGGTTTCGCCCCTATGCTCTATGTTCTATGTTCTCACTCCCGTGCTATAATCCCACGGTGATTTTTTATGT CCTGTGAGGAGCCTTAACCG
Downstream 100 bases:
>100_bases TGCTTAATCAAGTGGCGTAGTCAATAACTCGACTGCGCCACTGACTAAACTATAATACGCCCCTACAATCCTCAACAGGC CCGCTTGCTCACGCTGAGCC
Product: peptidylprolyl isomerase
Products: NA
Alternate protein names: PPIase B; Cyclophilin ScCypB; Rotamase B; S-cyclophilin [H]
Number of amino acids: Translated: 237; Mature: 237
Protein sequence:
>237_residues MRRTTTIALLALVLTACGSAESTAIPTIETRPTTAPTAEVAPTEASTGRPTTAPSDGGNTSSPGMPKQYASEPAMTIDVN KQYIATLKTQKGDIVIELNAKNAPRTVNNFVFLAREGFYDNVTFHRVIPGFMAQGGDPTGTGMGGPGYEFVNEYEDTTSN LLFDKAGVLAMANAGPNTNGSQFFITLAPALHLTPDAYTIFGQVTAGQDVVDQITPRDPNMGGAPGDAILTVTIEEK
Sequences:
>Translated_237_residues MRRTTTIALLALVLTACGSAESTAIPTIETRPTTAPTAEVAPTEASTGRPTTAPSDGGNTSSPGMPKQYASEPAMTIDVN KQYIATLKTQKGDIVIELNAKNAPRTVNNFVFLAREGFYDNVTFHRVIPGFMAQGGDPTGTGMGGPGYEFVNEYEDTTSN LLFDKAGVLAMANAGPNTNGSQFFITLAPALHLTPDAYTIFGQVTAGQDVVDQITPRDPNMGGAPGDAILTVTIEEK >Mature_237_residues MRRTTTIALLALVLTACGSAESTAIPTIETRPTTAPTAEVAPTEASTGRPTTAPSDGGNTSSPGMPKQYASEPAMTIDVN KQYIATLKTQKGDIVIELNAKNAPRTVNNFVFLAREGFYDNVTFHRVIPGFMAQGGDPTGTGMGGPGYEFVNEYEDTTSN LLFDKAGVLAMANAGPNTNGSQFFITLAPALHLTPDAYTIFGQVTAGQDVVDQITPRDPNMGGAPGDAILTVTIEEK
Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]
COG id: COG0652
COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PPIase cyclophilin-type domain [H]
Homologues:
Organism=Homo sapiens, GI7706339, Length=147, Percent_Identity=48.2993197278912, Blast_Score=129, Evalue=2e-30, Organism=Homo sapiens, GI64276486, Length=122, Percent_Identity=54.0983606557377, Blast_Score=129, Evalue=2e-30, Organism=Homo sapiens, GI24308049, Length=134, Percent_Identity=50, Blast_Score=124, Evalue=6e-29, Organism=Homo sapiens, GI19557636, Length=133, Percent_Identity=46.6165413533835, Blast_Score=114, Evalue=1e-25, Organism=Homo sapiens, GI5031987, Length=126, Percent_Identity=44.4444444444444, Blast_Score=91, Evalue=6e-19, Organism=Homo sapiens, GI22547215, Length=136, Percent_Identity=44.8529411764706, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI22547212, Length=136, Percent_Identity=44.8529411764706, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI7657473, Length=136, Percent_Identity=44.8529411764706, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI10863927, Length=127, Percent_Identity=43.3070866141732, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI20911035, Length=136, Percent_Identity=36.7647058823529, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI4758950, Length=127, Percent_Identity=43.3070866141732, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI4505991, Length=127, Percent_Identity=47.244094488189, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI42560244, Length=154, Percent_Identity=36.3636363636364, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI4826932, Length=128, Percent_Identity=41.40625, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI45439316, Length=131, Percent_Identity=40.4580152671756, Blast_Score=85, Evalue=5e-17, Organism=Homo sapiens, GI303305009, Length=127, Percent_Identity=41.7322834645669, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI310127646, Length=126, Percent_Identity=39.6825396825397, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI310114371, Length=126, Percent_Identity=39.6825396825397, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI310119221, Length=126, Percent_Identity=39.6825396825397, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI169163387, Length=129, Percent_Identity=38.7596899224806, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI5174637, Length=127, Percent_Identity=41.7322834645669, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI150418007, Length=148, Percent_Identity=39.1891891891892, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI169164185, Length=129, Percent_Identity=38.7596899224806, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI169163623, Length=129, Percent_Identity=38.7596899224806, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI310129267, Length=126, Percent_Identity=38.8888888888889, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI310120620, Length=126, Percent_Identity=38.8888888888889, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI256017253, Length=127, Percent_Identity=41.7322834645669, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI221139811, Length=127, Percent_Identity=41.7322834645669, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI256017251, Length=127, Percent_Identity=41.7322834645669, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI310110104, Length=126, Percent_Identity=38.8888888888889, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI6631100, Length=150, Percent_Identity=36.6666666666667, Blast_Score=81, Evalue=6e-16, Organism=Homo sapiens, GI178057341, Length=124, Percent_Identity=40.3225806451613, Blast_Score=79, Evalue=2e-15, Organism=Homo sapiens, GI209417936, Length=124, Percent_Identity=40.3225806451613, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI30102944, Length=124, Percent_Identity=40.3225806451613, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI219842199, Length=124, Percent_Identity=40.3225806451613, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI169214050, Length=134, Percent_Identity=36.5671641791045, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI310132444, Length=126, Percent_Identity=36.5079365079365, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI310113152, Length=126, Percent_Identity=36.5079365079365, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI239751853, Length=134, Percent_Identity=36.5671641791045, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI113428306, Length=134, Percent_Identity=36.5671641791045, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI27735045, Length=139, Percent_Identity=33.8129496402878, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI5454154, Length=139, Percent_Identity=35.9712230215827, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI289803023, Length=159, Percent_Identity=30.188679245283, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI310114540, Length=124, Percent_Identity=37.0967741935484, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI310127745, Length=118, Percent_Identity=38.135593220339, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI310119290, Length=118, Percent_Identity=38.135593220339, Blast_Score=70, Evalue=1e-12, Organism=Escherichia coli, GI1789763, Length=135, Percent_Identity=41.4814814814815, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1786736, Length=141, Percent_Identity=39.0070921985816, Blast_Score=81, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17539496, Length=128, Percent_Identity=53.125, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI17506311, Length=164, Percent_Identity=43.9024390243902, Blast_Score=113, Evalue=8e-26, Organism=Caenorhabditis elegans, GI17532641, Length=139, Percent_Identity=44.6043165467626, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI71997782, Length=148, Percent_Identity=43.9189189189189, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI71980594, Length=133, Percent_Identity=44.3609022556391, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI71980590, Length=133, Percent_Identity=44.3609022556391, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI32563659, Length=159, Percent_Identity=35.2201257861635, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17552780, Length=133, Percent_Identity=46.6165413533835, Blast_Score=88, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17552784, Length=136, Percent_Identity=40.4411764705882, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17506307, Length=128, Percent_Identity=45.3125, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17551284, Length=133, Percent_Identity=42.8571428571429, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17539498, Length=127, Percent_Identity=41.7322834645669, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17551282, Length=133, Percent_Identity=42.8571428571429, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17565860, Length=187, Percent_Identity=36.3636363636364, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17566266, Length=134, Percent_Identity=38.8059701492537, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17559074, Length=150, Percent_Identity=36.6666666666667, Blast_Score=78, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17532643, Length=131, Percent_Identity=40.4580152671756, Blast_Score=77, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17552782, Length=137, Percent_Identity=37.2262773722628, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI115533296, Length=130, Percent_Identity=36.9230769230769, Blast_Score=71, Evalue=4e-13, Organism=Saccharomyces cerevisiae, GI6321848, Length=137, Percent_Identity=45.2554744525547, Blast_Score=99, Evalue=6e-22, Organism=Saccharomyces cerevisiae, GI6323562, Length=152, Percent_Identity=43.421052631579, Blast_Score=97, Evalue=2e-21, Organism=Saccharomyces cerevisiae, GI6320510, Length=149, Percent_Identity=42.2818791946309, Blast_Score=92, Evalue=6e-20, Organism=Saccharomyces cerevisiae, GI6320359, Length=127, Percent_Identity=44.0944881889764, Blast_Score=90, Evalue=3e-19, Organism=Saccharomyces cerevisiae, GI6323246, Length=138, Percent_Identity=40.5797101449275, Blast_Score=83, Evalue=5e-17, Organism=Drosophila melanogaster, GI17986117, Length=135, Percent_Identity=52.5925925925926, Blast_Score=135, Evalue=3e-32, Organism=Drosophila melanogaster, GI19922376, Length=234, Percent_Identity=33.7606837606838, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI21357249, Length=122, Percent_Identity=46.7213114754098, Blast_Score=112, Evalue=1e-25, Organism=Drosophila melanogaster, GI19922912, Length=155, Percent_Identity=45.1612903225806, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI24652460, Length=135, Percent_Identity=41.4814814814815, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI45549139, Length=127, Percent_Identity=44.8818897637795, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI24664125, Length=156, Percent_Identity=39.1025641025641, Blast_Score=92, Evalue=2e-19, Organism=Drosophila melanogaster, GI21357783, Length=156, Percent_Identity=39.1025641025641, Blast_Score=92, Evalue=2e-19, Organism=Drosophila melanogaster, GI17647301, Length=148, Percent_Identity=37.8378378378378, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI24650807, Length=143, Percent_Identity=42.6573426573427, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI20130249, Length=128, Percent_Identity=45.3125, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24586038, Length=147, Percent_Identity=35.3741496598639, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI21355677, Length=136, Percent_Identity=33.0882352941176, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI17136360, Length=134, Percent_Identity=36.5671641791045, Blast_Score=69, Evalue=2e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015891 - InterPro: IPR020892 - InterPro: IPR002130 [H]
Pfam domain/function: PF00160 Pro_isomerase [H]
EC number: =5.2.1.8 [H]
Molecular weight: Translated: 24889; Mature: 24889
Theoretical pI: Translated: 4.40; Mature: 4.40
Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRRTTTIALLALVLTACGSAESTAIPTIETRPTTAPTAEVAPTEASTGRPTTAPSDGGNT CCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC SSPGMPKQYASEPAMTIDVNKQYIATLKTQKGDIVIELNAKNAPRTVNNFVFLAREGFYD CCCCCCHHHHCCCCEEEECCCEEEEEEEECCCCEEEEEECCCCCCCCCCEEEEEECCCCC NVTFHRVIPGFMAQGGDPTGTGMGGPGYEFVNEYEDTTSNLLFDKAGVLAMANAGPNTNG CEEHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHEEECCCCEEEEECCCCCCCC SQFFITLAPALHLTPDAYTIFGQVTAGQDVVDQITPRDPNMGGAPGDAILTVTIEEK CEEEEEECCEEEECCCCEEEEEEECCCHHHHHHCCCCCCCCCCCCCCEEEEEEEECC >Mature Secondary Structure MRRTTTIALLALVLTACGSAESTAIPTIETRPTTAPTAEVAPTEASTGRPTTAPSDGGNT CCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC SSPGMPKQYASEPAMTIDVNKQYIATLKTQKGDIVIELNAKNAPRTVNNFVFLAREGFYD CCCCCCHHHHCCCCEEEECCCEEEEEEEECCCCEEEEEECCCCCCCCCCEEEEEECCCCC NVTFHRVIPGFMAQGGDPTGTGMGGPGYEFVNEYEDTTSNLLFDKAGVLAMANAGPNTNG CEEHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHEEECCCCEEEEECCCCCCCC SQFFITLAPALHLTPDAYTIFGQVTAGQDVVDQITPRDPNMGGAPGDAILTVTIEEK CEEEEEECCEEEECCCCEEEEEEECCCHHHHHHCCCCCCCCCCCCCCEEEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9025285 [H]