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The map label for this gene is clpB [H]

Identifier: 159900113

GI number: 159900113

Start: 4525888

End: 4527069

Strand: Reverse

Name: clpB [H]

Synonym: Haur_3596

Alternate gene names: 159900113

Gene position: 4527069-4525888 (Counterclockwise)

Preceding gene: 159900114

Following gene: 159900110

Centisome position: 71.33

GC content: 51.27

Gene sequence:

>1182_bases
ATGGATGAACAGCAAAAAACACCGATCAGCGGTTCCATGCAACGAGCGGTGCGCGGTGATAAAAACCCACTCGATGCCGT
TGAACAAGAATTACGCACCAGCGTCTTTGGCCAAAATCGCGCGATCGAAAGCTTAATTCGTGCCCTGAATCGTGCTCGCT
TTGGCTTTAGTGCTGGTAGTCAGCAGCGTCCACGCGCAACGTTGCTGTTTCTTGGGCCAACTGGCGTTGGTAAAAGTGAA
TGTGCTAAGCGCTTAGCTGCATTTTTACATCCGCAAGGCGGTGGGTTTCTCAAGCTCGATTGTTCGCTGTTTAGCCAAGG
CCACGAAGTTTCGGCGTTGCTTGGCGCTCCTCCCTCCTACGTCGGACGCGATCAAAAGCCCTTGCTCGACCCTGAGTTGA
TCGAGCAAGAAAATGCGGTGATCTTGTTTGACGAAATTGAAAAAGCCACATCCGAGCTTTGGAATTTGTTGCTGCAAATC
ATGGAAGATGGCGAGATTACCTTGCTCAACGGTGGGCGCAAAGTTTCATTCCATCGCGCTATTGTTATCATGACCACGAA
TGTTGGCGCTCAGGAAATGGCAAATTATGTCTCGCAACGCACCATCGGTTTCCGCACACCCAATCGCGTCGTCGAATCGA
CTGGCCAACAAATTTATCAAATCGGCTTTGAATCGCTGCAAAAGGTCTTTAGTCCTGAATGGATCAACCGGATCGATGAA
ATTATCGCTTTCCGGCCATTAAGCAGCGACACATTGCGCCAAGTCCTTGATCGCATGGTCGCTGAATCGAATGAGCAATA
TCGTCGCCATGGAGTGGAAATTAGCTTAAACGAGGAAGCCCGCGATTATATTTTGCGCCGTGGTTTCGACCCACGTTTTG
GCGCTCGCCCGTTGCGCTCCCGTTTGATGAAGGATATCGATGCTCCATTGGCCGATTTGCTCGCTTCGGGCGGGATTCCC
AGCGGGGCAAAAGTGCAAATTGTGGTCTCGGAAGAAGAAGCCAAGGATGGCAATAATCTCGATTTCTTCTACGAGCCTGA
TGCAACCTTGGCGGCCTTTGCCGCAGATTATGCGGCTAAGCAAGAGCAAGCTCCGCCATCAGCCCGTGAAGTTGCTGGGC
CACCGTCACATACCCCTGGCCCATCGATTGCTCGCTCAACCGAAAACAATAATCGACGCTAA

Upstream 100 bases:

>100_bases
AAAAAACAGTACTAAGCATCCTTGACTCAGCAAAAACCCGTGGGATACAATAGTCTCACGGGTTTTGCCATGGTTGCCGT
ATCTGTCTTGGAGGTAAAGT

Downstream 100 bases:

>100_bases
GTTCCCTCACCCCAACCCCTCTCCCACTGAACGCGGGAGAGGGGCTTTTTTTACGTCTCGTTGGGCGAAAGCAGGGCTGA
GGGAACTTAAAAGCGTTGAC

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MDEQQKTPISGSMQRAVRGDKNPLDAVEQELRTSVFGQNRAIESLIRALNRARFGFSAGSQQRPRATLLFLGPTGVGKSE
CAKRLAAFLHPQGGGFLKLDCSLFSQGHEVSALLGAPPSYVGRDQKPLLDPELIEQENAVILFDEIEKATSELWNLLLQI
MEDGEITLLNGGRKVSFHRAIVIMTTNVGAQEMANYVSQRTIGFRTPNRVVESTGQQIYQIGFESLQKVFSPEWINRIDE
IIAFRPLSSDTLRQVLDRMVAESNEQYRRHGVEISLNEEARDYILRRGFDPRFGARPLRSRLMKDIDAPLADLLASGGIP
SGAKVQIVVSEEEAKDGNNLDFFYEPDATLAAFAADYAAKQEQAPPSAREVAGPPSHTPGPSIARSTENNNRR

Sequences:

>Translated_393_residues
MDEQQKTPISGSMQRAVRGDKNPLDAVEQELRTSVFGQNRAIESLIRALNRARFGFSAGSQQRPRATLLFLGPTGVGKSE
CAKRLAAFLHPQGGGFLKLDCSLFSQGHEVSALLGAPPSYVGRDQKPLLDPELIEQENAVILFDEIEKATSELWNLLLQI
MEDGEITLLNGGRKVSFHRAIVIMTTNVGAQEMANYVSQRTIGFRTPNRVVESTGQQIYQIGFESLQKVFSPEWINRIDE
IIAFRPLSSDTLRQVLDRMVAESNEQYRRHGVEISLNEEARDYILRRGFDPRFGARPLRSRLMKDIDAPLADLLASGGIP
SGAKVQIVVSEEEAKDGNNLDFFYEPDATLAAFAADYAAKQEQAPPSAREVAGPPSHTPGPSIARSTENNNRR
>Mature_393_residues
MDEQQKTPISGSMQRAVRGDKNPLDAVEQELRTSVFGQNRAIESLIRALNRARFGFSAGSQQRPRATLLFLGPTGVGKSE
CAKRLAAFLHPQGGGFLKLDCSLFSQGHEVSALLGAPPSYVGRDQKPLLDPELIEQENAVILFDEIEKATSELWNLLLQI
MEDGEITLLNGGRKVSFHRAIVIMTTNVGAQEMANYVSQRTIGFRTPNRVVESTGQQIYQIGFESLQKVFSPEWINRIDE
IIAFRPLSSDTLRQVLDRMVAESNEQYRRHGVEISLNEEARDYILRRGFDPRFGARPLRSRLMKDIDAPLADLLASGGIP
SGAKVQIVVSEEEAKDGNNLDFFYEPDATLAAFAADYAAKQEQAPPSAREVAGPPSHTPGPSIARSTENNNRR

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=325, Percent_Identity=30.4615384615385, Blast_Score=145, Evalue=5e-35,
Organism=Escherichia coli, GI1787109, Length=316, Percent_Identity=36.7088607594937, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1788943, Length=321, Percent_Identity=33.9563862928349, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1786642, Length=374, Percent_Identity=25.668449197861, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320464, Length=321, Percent_Identity=34.8909657320872, Blast_Score=194, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6323002, Length=316, Percent_Identity=32.5949367088608, Blast_Score=160, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 43493; Mature: 43493

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEQQKTPISGSMQRAVRGDKNPLDAVEQELRTSVFGQNRAIESLIRALNRARFGFSAGS
CCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
QQRPRATLLFLGPTGVGKSECAKRLAAFLHPQGGGFLKLDCSLFSQGHEVSALLGAPPSY
CCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCEEHHHCCCHHH
VGRDQKPLLDPELIEQENAVILFDEIEKATSELWNLLLQIMEDGEITLLNGGRKVSFHRA
CCCCCCCCCCHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEEEE
IVIMTTNVGAQEMANYVSQRTIGFRTPNRVVESTGQQIYQIGFESLQKVFSPEWINRIDE
EEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
IIAFRPLSSDTLRQVLDRMVAESNEQYRRHGVEISLNEEARDYILRRGFDPRFGARPLRS
HHHCCCCCHHHHHHHHHHHHHCCCHHHHHCCCEEEECHHHHHHHHHCCCCCCCCCCHHHH
RLMKDIDAPLADLLASGGIPSGAKVQIVVSEEEAKDGNNLDFFYEPDATLAAFAADYAAK
HHHHHHCCCHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCEEECCCCHHHHHHHHHHHH
QEQAPPSAREVAGPPSHTPGPSIARSTENNNRR
HHCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDEQQKTPISGSMQRAVRGDKNPLDAVEQELRTSVFGQNRAIESLIRALNRARFGFSAGS
CCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
QQRPRATLLFLGPTGVGKSECAKRLAAFLHPQGGGFLKLDCSLFSQGHEVSALLGAPPSY
CCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCEEHHHCCCHHH
VGRDQKPLLDPELIEQENAVILFDEIEKATSELWNLLLQIMEDGEITLLNGGRKVSFHRA
CCCCCCCCCCHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEEEE
IVIMTTNVGAQEMANYVSQRTIGFRTPNRVVESTGQQIYQIGFESLQKVFSPEWINRIDE
EEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
IIAFRPLSSDTLRQVLDRMVAESNEQYRRHGVEISLNEEARDYILRRGFDPRFGARPLRS
HHHCCCCCHHHHHHHHHHHHHCCCHHHHHCCCEEEECHHHHHHHHHCCCCCCCCCCHHHH
RLMKDIDAPLADLLASGGIPSGAKVQIVVSEEEAKDGNNLDFFYEPDATLAAFAADYAAK
HHHHHHCCCHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCEEECCCCHHHHHHHHHHHH
QEQAPPSAREVAGPPSHTPGPSIARSTENNNRR
HHCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]