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The map label for this gene is rsbRA [H]

Identifier: 159900044

GI number: 159900044

Start: 4439236

End: 4441239

Strand: Reverse

Name: rsbRA [H]

Synonym: Haur_3527

Alternate gene names: 159900044

Gene position: 4441239-4439236 (Counterclockwise)

Preceding gene: 159900049

Following gene: 159900043

Centisome position: 69.98

GC content: 51.55

Gene sequence:

>2004_bases
ATGGCCCAAGACCCGCCTTCATCTGTCGATTTAGCTGCTCGGCTGGCTCAGCTTGAACGTGAAAATCGTATTTTACAGGC
CATGCTCGACACGGTGCCTGATGCGATTGTGTTTAAAAATGCTGATCTCACGATTGAGTATGCCAATCGCGCTTTTCGCG
AATGGTTTGGCTTGCCGCTTGAGCAGTTTCATGTAGCCGATGATCGTTCGGGCGATGATGCCTATGCCTCAGAATATCAA
AGCCACGATCGCCAAGTCTTACGTAGTGGCCTTGGTAGCGAGTTTGAGGAGCGCTCAAATGCGCCCGATGGCTCGTTGAT
TACCACCCGTAGCATCAAACAACCAGTGCGTGATGCTAACCAAGTCATTGGCTTGGTGGCAGTGTTGCGCGATGTAACCA
GTGCGGCCCAAGCTTCGCGCTCACTGACGGAAACCCAAGCCCGACTTTCGCGGATTATCTCGAATGTGCCTGGCATGGTT
TTTCAGTTTGTGCTGCATCCCGATGGCACAAGCGAGTTTCCCTATGTGAGCGAGGGCATTCGCCAAGCCTTTGGCATCGA
GCCAGAACGCCTGACTTCGGAGCGCGATGCTCTCTATAACTGGGTGCATCCCGAAGATCAGCCAGAATTTATCCGTTCGT
TTGTTGAATCGGGCCAGTTGCTCGAACCTTGGCAATGGGAAGGCCGTGTGGTCTACGATGGTGTTGTGCGCTGGGTACGC
GGTGCTTCGCGGCCAACTCGCACCGAGGCTGGTGATATTTTGTGGGATGGCGTGTTGATGGATATTACCTTGCAACGCGA
AAATGAAGCTGCGTTGCGCCGTCTGCAAAATCGTTTGCAACAGTTTCTTGATGCGACTCCCGTTGGTTTGTATGTGGTCG
AGCCTGATGGCAAGCCCTATTATGCCAATGCCAAAGCCCAAGAGTTGCTCGGCCAACATGTGATGCTGCCAGTCAGCCAG
CAAACCGAGACCTATCGCACCTACAAAATTGGCAGTGAAACGCTCTATCCGCGCGAAGAATTGCCAACCCAACGCGCCCT
CAAGGGCGAAATGGTGCACCTTGATGATCTTGAATTTCGCTATGCCGATAAGCCTGCAACTGCAATTGAGGTTTATGCCC
GCCCGATTTACGACCCCAATGATCAAATTGAATATGCCATCGCCACCTTTTTCGATATTACCGAGCGCCGCCAAATTGCC
CAAGAATTGTTTGATTGGCGGCAACGCTTCGATCTGATCATGTCAACCGTCGAGTTGGTGATGTACGATTACGATGTGAC
CAACAATAAAATTGAATGGAGCGATTCGGTCACCAAGATTTTGGGCTATCCCAAGGCCGAATTTAGCCTGAGCCTTGATG
CATGGGCTGCTGGTTTACACCCCGACGATGCCCCCGAAGCCTTGCGCTTGCTCGAAATTGCCCAAGAAAATTGCAGTACC
TATGCGGTTGAATATCGCTTTTTACATCATTCTGGTCATTGGCTCTGGCTCTTAGATCGTGGGTTCTTTATTCCAAACAA
CGATGGTGTGGCAATTCGCATGTTGGGCTTGGTGCAAGATATTACTGAACGCAAACAAGCTGAAGTGATGCGCGAACAAA
TGCAGGGCCAAATTATCGAAGCTCAAGCTGCCGCGCTCCGCGAACTTTCCACGCCATTAATCCCAATCAACGATCGCACG
GTGATTATGCCACTGATTGGCTCGATTGATTCAGCACGCGCGACCCAAATTGTCGAATCGCTGCTGCAAGGTGTGAGCCA
AATGAACGCTGGCGTGGTGATTCTCGACTTAACTGGGGTTCCAGTCGTCGATACCCAAGTTGCTAGTGCTTTGTTGCAGG
CGGCGCGGGCCGTGCGTTTGCTGGGCGCTGAGGTGGTATTAACCGGAATTCGCCCAGAAATTGCTCAAACCTTGGTTAGC
TTGGGCATTAGTTTGGGCGATGTTGTGACCTTGAGCAATTTACAAAGCGGGATCGAACGCGCCTTGAATCGCCGTTTATC
CTAA

Upstream 100 bases:

>100_bases
CTTTTGAGGTTCTCACTATTCCCTCGCCTAAACGTCTATGGTAAAATTAAGCTACTTCCGCGTTTGCGCCCATCGCCAAA
GGATTTTTAGGAGTGCAGCT

Downstream 100 bases:

>100_bases
GCGAGGGGGTTTGTATCAACCCTGAAACTGAAATTTGGGCAACGGAATTAGCGGCGGCGATCGCCCATACCATTCAAGCG
CATACATTTCAAGCACGAAC

Product: putative PAS/PAC sensor protein

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 667; Mature: 666

Protein sequence:

>667_residues
MAQDPPSSVDLAARLAQLERENRILQAMLDTVPDAIVFKNADLTIEYANRAFREWFGLPLEQFHVADDRSGDDAYASEYQ
SHDRQVLRSGLGSEFEERSNAPDGSLITTRSIKQPVRDANQVIGLVAVLRDVTSAAQASRSLTETQARLSRIISNVPGMV
FQFVLHPDGTSEFPYVSEGIRQAFGIEPERLTSERDALYNWVHPEDQPEFIRSFVESGQLLEPWQWEGRVVYDGVVRWVR
GASRPTRTEAGDILWDGVLMDITLQRENEAALRRLQNRLQQFLDATPVGLYVVEPDGKPYYANAKAQELLGQHVMLPVSQ
QTETYRTYKIGSETLYPREELPTQRALKGEMVHLDDLEFRYADKPATAIEVYARPIYDPNDQIEYAIATFFDITERRQIA
QELFDWRQRFDLIMSTVELVMYDYDVTNNKIEWSDSVTKILGYPKAEFSLSLDAWAAGLHPDDAPEALRLLEIAQENCST
YAVEYRFLHHSGHWLWLLDRGFFIPNNDGVAIRMLGLVQDITERKQAEVMREQMQGQIIEAQAAALRELSTPLIPINDRT
VIMPLIGSIDSARATQIVESLLQGVSQMNAGVVILDLTGVPVVDTQVASALLQAARAVRLLGAEVVLTGIRPEIAQTLVS
LGISLGDVVTLSNLQSGIERALNRRLS

Sequences:

>Translated_667_residues
MAQDPPSSVDLAARLAQLERENRILQAMLDTVPDAIVFKNADLTIEYANRAFREWFGLPLEQFHVADDRSGDDAYASEYQ
SHDRQVLRSGLGSEFEERSNAPDGSLITTRSIKQPVRDANQVIGLVAVLRDVTSAAQASRSLTETQARLSRIISNVPGMV
FQFVLHPDGTSEFPYVSEGIRQAFGIEPERLTSERDALYNWVHPEDQPEFIRSFVESGQLLEPWQWEGRVVYDGVVRWVR
GASRPTRTEAGDILWDGVLMDITLQRENEAALRRLQNRLQQFLDATPVGLYVVEPDGKPYYANAKAQELLGQHVMLPVSQ
QTETYRTYKIGSETLYPREELPTQRALKGEMVHLDDLEFRYADKPATAIEVYARPIYDPNDQIEYAIATFFDITERRQIA
QELFDWRQRFDLIMSTVELVMYDYDVTNNKIEWSDSVTKILGYPKAEFSLSLDAWAAGLHPDDAPEALRLLEIAQENCST
YAVEYRFLHHSGHWLWLLDRGFFIPNNDGVAIRMLGLVQDITERKQAEVMREQMQGQIIEAQAAALRELSTPLIPINDRT
VIMPLIGSIDSARATQIVESLLQGVSQMNAGVVILDLTGVPVVDTQVASALLQAARAVRLLGAEVVLTGIRPEIAQTLVS
LGISLGDVVTLSNLQSGIERALNRRLS
>Mature_666_residues
AQDPPSSVDLAARLAQLERENRILQAMLDTVPDAIVFKNADLTIEYANRAFREWFGLPLEQFHVADDRSGDDAYASEYQS
HDRQVLRSGLGSEFEERSNAPDGSLITTRSIKQPVRDANQVIGLVAVLRDVTSAAQASRSLTETQARLSRIISNVPGMVF
QFVLHPDGTSEFPYVSEGIRQAFGIEPERLTSERDALYNWVHPEDQPEFIRSFVESGQLLEPWQWEGRVVYDGVVRWVRG
ASRPTRTEAGDILWDGVLMDITLQRENEAALRRLQNRLQQFLDATPVGLYVVEPDGKPYYANAKAQELLGQHVMLPVSQQ
TETYRTYKIGSETLYPREELPTQRALKGEMVHLDDLEFRYADKPATAIEVYARPIYDPNDQIEYAIATFFDITERRQIAQ
ELFDWRQRFDLIMSTVELVMYDYDVTNNKIEWSDSVTKILGYPKAEFSLSLDAWAAGLHPDDAPEALRLLEIAQENCSTY
AVEYRFLHHSGHWLWLLDRGFFIPNNDGVAIRMLGLVQDITERKQAEVMREQMQGQIIEAQAAALRELSTPLIPINDRTV
IMPLIGSIDSARATQIVESLLQGVSQMNAGVVILDLTGVPVVDTQVASALLQAARAVRLLGAEVVLTGIRPEIAQTLVSL
GISLGDVVTLSNLQSGIERALNRRLS

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 75071; Mature: 74940

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQDPPSSVDLAARLAQLERENRILQAMLDTVPDAIVFKNADLTIEYANRAFREWFGLPL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEHHHHHHHHHHHCCCH
EQFHVADDRSGDDAYASEYQSHDRQVLRSGLGSEFEERSNAPDGSLITTRSIKQPVRDAN
HHHEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEHHHHHHHHHHHH
QVIGLVAVLRDVTSAAQASRSLTETQARLSRIISNVPGMVFQFVLHPDGTSEFPYVSEGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCHHHHHH
RQAFGIEPERLTSERDALYNWVHPEDQPEFIRSFVESGQLLEPWQWEGRVVYDGVVRWVR
HHHHCCCHHHHCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHH
GASRPTRTEAGDILWDGVLMDITLQRENEAALRRLQNRLQQFLDATPVGLYVVEPDGKPY
CCCCCCCCCCCCCEECCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCE
YANAKAQELLGQHVMLPVSQQTETYRTYKIGSETLYPREELPTQRALKGEMVHLDDLEFR
ECCCHHHHHHCCCEECCCCCCCCCHHEEECCCCCCCCHHHCCHHHHHCCCEEEECCCCEE
YADKPATAIEVYARPIYDPNDQIEYAIATFFDITERRQIAQELFDWRQRFDLIMSTVELV
ECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MYDYDVTNNKIEWSDSVTKILGYPKAEFSLSLDAWAAGLHPDDAPEALRLLEIAQENCST
HEECCCCCCEEECCHHHHHHHCCCCCCEEEEHHHHCCCCCCCCHHHHHHHHHHHHHCCCE
YAVEYRFLHHSGHWLWLLDRGFFIPNNDGVAIRMLGLVQDITERKQAEVMREQMQGQIIE
EEEEEEEEEECCCEEEEEECCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AQAAALRELSTPLIPINDRTVIMPLIGSIDSARATQIVESLLQGVSQMNAGVVILDLTGV
HHHHHHHHHCCCEECCCCCEEEEEHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
PVVDTQVASALLQAARAVRLLGAEVVLTGIRPEIAQTLVSLGISLGDVVTLSNLQSGIER
CEEHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ALNRRLS
HHHHCCC
>Mature Secondary Structure 
AQDPPSSVDLAARLAQLERENRILQAMLDTVPDAIVFKNADLTIEYANRAFREWFGLPL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEHHHHHHHHHHHCCCH
EQFHVADDRSGDDAYASEYQSHDRQVLRSGLGSEFEERSNAPDGSLITTRSIKQPVRDAN
HHHEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEHHHHHHHHHHHH
QVIGLVAVLRDVTSAAQASRSLTETQARLSRIISNVPGMVFQFVLHPDGTSEFPYVSEGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCHHHHHH
RQAFGIEPERLTSERDALYNWVHPEDQPEFIRSFVESGQLLEPWQWEGRVVYDGVVRWVR
HHHHCCCHHHHCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHH
GASRPTRTEAGDILWDGVLMDITLQRENEAALRRLQNRLQQFLDATPVGLYVVEPDGKPY
CCCCCCCCCCCCCEECCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCE
YANAKAQELLGQHVMLPVSQQTETYRTYKIGSETLYPREELPTQRALKGEMVHLDDLEFR
ECCCHHHHHHCCCEECCCCCCCCCHHEEECCCCCCCCHHHCCHHHHHCCCEEEECCCCEE
YADKPATAIEVYARPIYDPNDQIEYAIATFFDITERRQIAQELFDWRQRFDLIMSTVELV
ECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MYDYDVTNNKIEWSDSVTKILGYPKAEFSLSLDAWAAGLHPDDAPEALRLLEIAQENCST
HEECCCCCCEEECCHHHHHHHCCCCCCEEEEHHHHCCCCCCCCHHHHHHHHHHHHHCCCE
YAVEYRFLHHSGHWLWLLDRGFFIPNNDGVAIRMLGLVQDITERKQAEVMREQMQGQIIE
EEEEEEEEEECCCEEEEEECCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AQAAALRELSTPLIPINDRTVIMPLIGSIDSARATQIVESLLQGVSQMNAGVVILDLTGV
HHHHHHHHHCCCEECCCCCEEEEEHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
PVVDTQVASALLQAARAVRLLGAEVVLTGIRPEIAQTLVSLGISLGDVVTLSNLQSGIER
CEEHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ALNRRLS
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]