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The map label for this gene is p20 [H]

Identifier: 159900000

GI number: 159900000

Start: 4386005

End: 4386571

Strand: Reverse

Name: p20 [H]

Synonym: Haur_3483

Alternate gene names: 159900000

Gene position: 4386571-4386005 (Counterclockwise)

Preceding gene: 159900002

Following gene: 159899999

Centisome position: 69.12

GC content: 48.68

Gene sequence:

>567_bases
ATGTTTAGCTCAAATCGTTTGACCCTGCGGTCAGTTGGTCAAGAAGATCTGCCGATTTTTCATCAGTGGTGGGGTGACCC
AGAAATTATGGCTCTGCAAACCGATGGCGATATTCGGTTGCGCCATGAAACCACCAATGTGATGATGTTTGACCATTGGT
TTCGCGATGGTGGCAGCGATGTGGGCTTCTCGATTGAACTCAGCGAGACTGGCCAGTTGATTGGCTTTACCAATGTTTGG
GGGGCGCAATTAAAAAATCGCTCAGCCGAATTGGGGATTATGCTCGATAAAGATTTTTGGAACTGCGGCTATGGCACCGA
AGCGATGCATGTAATTGTGCGTTATGTTTTTGCTGAGCTGAATTTTCACCGTTTGCAATTGACGGTGCGCGATTACAACC
AACGGGCGCAGCGCGTCTATAGCAAAGTTGGCTTTCAAGTCACTGGGCGTTTGCGCCAGATCAATTTTCGCAATGGCCGT
TGGCACGATGATCTAGTGATGGATTTGTTGCAGGATGAATATTTAGCCGCCCATGGAGCCTACCCGTCTAGCCCAACTAT
GCCCTAA

Upstream 100 bases:

>100_bases
GATCAACTTGGTTCAGATCGAGCATGTTCATTCCTCTCACCCCAAAATTGCTGATACCGTGCTACAATCAGCGCTGCTTA
ATTACACTGGAGTATACCCC

Downstream 100 bases:

>100_bases
ATAGCTATAGACCGATCGTAACTTCATGGTATAGTGATAGACAATCGCGACATGAACCGCGCCCGATGTTTTCGGCGCGG
TTTTGTATTAACTTAAATCA

Product: GCN5-like N-acetyltransferase

Products: Coenzyme A; H+; N8-Acetylspermidine [C]

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MFSSNRLTLRSVGQEDLPIFHQWWGDPEIMALQTDGDIRLRHETTNVMMFDHWFRDGGSDVGFSIELSETGQLIGFTNVW
GAQLKNRSAELGIMLDKDFWNCGYGTEAMHVIVRYVFAELNFHRLQLTVRDYNQRAQRVYSKVGFQVTGRLRQINFRNGR
WHDDLVMDLLQDEYLAAHGAYPSSPTMP

Sequences:

>Translated_188_residues
MFSSNRLTLRSVGQEDLPIFHQWWGDPEIMALQTDGDIRLRHETTNVMMFDHWFRDGGSDVGFSIELSETGQLIGFTNVW
GAQLKNRSAELGIMLDKDFWNCGYGTEAMHVIVRYVFAELNFHRLQLTVRDYNQRAQRVYSKVGFQVTGRLRQINFRNGR
WHDDLVMDLLQDEYLAAHGAYPSSPTMP
>Mature_188_residues
MFSSNRLTLRSVGQEDLPIFHQWWGDPEIMALQTDGDIRLRHETTNVMMFDHWFRDGGSDVGFSIELSETGQLIGFTNVW
GAQLKNRSAELGIMLDKDFWNCGYGTEAMHVIVRYVFAELNFHRLQLTVRDYNQRAQRVYSKVGFQVTGRLRQINFRNGR
WHDDLVMDLLQDEYLAAHGAYPSSPTMP

Specific function: Regulates Polyamine Concentration By Their Degradation. Acts On Spermidine, Forming N(1)- And N(8)-Acetylspermidine. [C]

COG id: COG1670

COG function: function code J; Acetyltransferases, including N-acetylases of ribosomal proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1787867, Length=178, Percent_Identity=28.0898876404494, Blast_Score=70, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: 2.3.1.57 [C]

Molecular weight: Translated: 21835; Mature: 21835

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSSNRLTLRSVGQEDLPIFHQWWGDPEIMALQTDGDIRLRHETTNVMMFDHWFRDGGSD
CCCCCCEEHHHCCCCCCCHHHHHCCCCEEEEEECCCCEEEEEECCEEEEEEEECCCCCCC
VGFSIELSETGQLIGFTNVWGAQLKNRSAELGIMLDKDFWNCGYGTEAMHVIVRYVFAEL
CEEEEEECCCCCEEEECCHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHC
NFHRLQLTVRDYNQRAQRVYSKVGFQVTGRLRQINFRNGRWHDDLVMDLLQDEYLAAHGA
CEEEEEEEEHHHHHHHHHHHHHCCEEEECEEEEEECCCCCCHHHHHHHHHHHHHHHHCCC
YPSSPTMP
CCCCCCCC
>Mature Secondary Structure
MFSSNRLTLRSVGQEDLPIFHQWWGDPEIMALQTDGDIRLRHETTNVMMFDHWFRDGGSD
CCCCCCEEHHHCCCCCCCHHHHHCCCCEEEEEECCCCEEEEEECCEEEEEEEECCCCCCC
VGFSIELSETGQLIGFTNVWGAQLKNRSAELGIMLDKDFWNCGYGTEAMHVIVRYVFAEL
CEEEEEECCCCCEEEECCHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHC
NFHRLQLTVRDYNQRAQRVYSKVGFQVTGRLRQINFRNGRWHDDLVMDLLQDEYLAAHGA
CEEEEEEEEHHHHHHHHHHHHHCCEEEECEEEEEECCCCCCHHHHHHHHHHHHHHHHCCC
YPSSPTMP
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; Spermidine [C]

Specific reaction: Acetyl-CoA + Spermidine --> Coenzyme A + H+ + N8-Acetylspermidine [C]

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2838827 [H]