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The map label for this gene is trxA [H]

Identifier: 159899669

GI number: 159899669

Start: 3979221

End: 3979562

Strand: Reverse

Name: trxA [H]

Synonym: Haur_3151

Alternate gene names: 159899669

Gene position: 3979562-3979221 (Counterclockwise)

Preceding gene: 159899672

Following gene: 159899667

Centisome position: 62.7

GC content: 51.75

Gene sequence:

>342_bases
ATGCAAACCGTGATTGATCAGCCAGTTCAGGTTAGCGATGCCAGCTTTGAAACGCAGGTATTGCAATCGGATACGCCAGT
CATTGTCGATTTTTGGGCACCTTGGTGTGGGCATTGCCGCGTGATTGCGCCAATTTTGGCCAAGTTGGCACAGCGCTATG
CAGGCGAAATTGTGGTTGCCAAAATCAATACCGACGAAGACGTGCAATATGCCAGCCGTTTAGGTGTGCGTGGTTTGCCC
ACAATGGTGGTATTTCAGCATGGTCAAGAGGTTGATCGCTGGATTGGGGCGATGAGCGAAGCTGCGTTCGAGCAACGTGT
GCAACAGCTGCTTGGGCGTTAA

Upstream 100 bases:

>100_bases
GACCCCTGAAATTGCTGCTTGACTTCCAGTTAACTTGAACTTGTAGACTGCCAACGAGCTACTGTAATCATGCAATAGCT
GTCAAGTGGAGGTCGCGTTC

Downstream 100 bases:

>100_bases
ATGATAACAGGCAGGCTGCTTCTCACGGCGGCCTGCCTGTTTATTCTTCCTCGGTAAATTATCTAGGCTCCCACAAGCGG
ACTATTGGCATTCTTCCAAC

Product: thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MQTVIDQPVQVSDASFETQVLQSDTPVIVDFWAPWCGHCRVIAPILAKLAQRYAGEIVVAKINTDEDVQYASRLGVRGLP
TMVVFQHGQEVDRWIGAMSEAAFEQRVQQLLGR

Sequences:

>Translated_113_residues
MQTVIDQPVQVSDASFETQVLQSDTPVIVDFWAPWCGHCRVIAPILAKLAQRYAGEIVVAKINTDEDVQYASRLGVRGLP
TMVVFQHGQEVDRWIGAMSEAAFEQRVQQLLGR
>Mature_113_residues
MQTVIDQPVQVSDASFETQVLQSDTPVIVDFWAPWCGHCRVIAPILAKLAQRYAGEIVVAKINTDEDVQYASRLGVRGLP
TMVVFQHGQEVDRWIGAMSEAAFEQRVQQLLGR

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361403, Length=97, Percent_Identity=35.0515463917526, Blast_Score=82, Evalue=1e-16,
Organism=Homo sapiens, GI5031973, Length=107, Percent_Identity=31.7757009345794, Blast_Score=70, Evalue=3e-13,
Organism=Homo sapiens, GI21361657, Length=92, Percent_Identity=33.695652173913, Blast_Score=68, Evalue=1e-12,
Organism=Homo sapiens, GI224493972, Length=106, Percent_Identity=31.1320754716981, Blast_Score=67, Evalue=2e-12,
Organism=Homo sapiens, GI42794771, Length=106, Percent_Identity=31.1320754716981, Blast_Score=66, Evalue=6e-12,
Organism=Homo sapiens, GI4758304, Length=103, Percent_Identity=35.9223300970874, Blast_Score=66, Evalue=6e-12,
Organism=Homo sapiens, GI20070125, Length=73, Percent_Identity=39.7260273972603, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082331, Length=100, Percent_Identity=41, Blast_Score=105, Evalue=8e-25,
Organism=Escherichia coli, GI1788936, Length=104, Percent_Identity=41.3461538461538, Blast_Score=99, Evalue=7e-23,
Organism=Escherichia coli, GI87081747, Length=110, Percent_Identity=32.7272727272727, Blast_Score=75, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI212646193, Length=96, Percent_Identity=32.2916666666667, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17556044, Length=80, Percent_Identity=35, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115532378, Length=102, Percent_Identity=38.2352941176471, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17544108, Length=70, Percent_Identity=44.2857142857143, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115532380, Length=70, Percent_Identity=44.2857142857143, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17549970, Length=86, Percent_Identity=32.5581395348837, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321648, Length=96, Percent_Identity=34.375, Blast_Score=71, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323072, Length=94, Percent_Identity=35.1063829787234, Blast_Score=67, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24639826, Length=93, Percent_Identity=36.5591397849462, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19921434, Length=80, Percent_Identity=38.75, Blast_Score=76, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28573567, Length=81, Percent_Identity=37.037037037037, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17647799, Length=91, Percent_Identity=35.1648351648352, Blast_Score=66, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17648013, Length=90, Percent_Identity=35.5555555555556, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24583090, Length=90, Percent_Identity=35.5555555555556, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24639068, Length=92, Percent_Identity=30.4347826086957, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21358065, Length=89, Percent_Identity=38.2022471910112, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 12627; Mature: 12627

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTVIDQPVQVSDASFETQVLQSDTPVIVDFWAPWCGHCRVIAPILAKLAQRYAGEIVVA
CCCCCCCCCCCCCCCHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEE
KINTDEDVQYASRLGVRGLPTMVVFQHGQEVDRWIGAMSEAAFEQRVQQLLGR
EECCCHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQTVIDQPVQVSDASFETQVLQSDTPVIVDFWAPWCGHCRVIAPILAKLAQRYAGEIVVA
CCCCCCCCCCCCCCCHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEE
KINTDEDVQYASRLGVRGLPTMVVFQHGQEVDRWIGAMSEAAFEQRVQQLLGR
EECCCHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA