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The map label for this gene is udg [H]

Identifier: 159899657

GI number: 159899657

Start: 3966510

End: 3967886

Strand: Reverse

Name: udg [H]

Synonym: Haur_3139

Alternate gene names: 159899657

Gene position: 3967886-3966510 (Counterclockwise)

Preceding gene: 159899658

Following gene: 159899655

Centisome position: 62.52

GC content: 49.89

Gene sequence:

>1377_bases
ATGAAGATCGTCGTTGCAGGAACAGGCTTTGTGGGATTGCCCCACGCTGCGGTCTGCTCAGAATATGGTCATGAAGTCTA
TGCCTATGATATTGATACGAAGCGGATTGCGGCTTACAAAACCGCCAAGCGCGAAGAAATTGAAAAATATGTCAATGAGC
CAGGCTTGGCCAGCATTATCCAAGAAAATATCAACCGTTCTCTGCATTTCATTGATGATCTTGAGCCGGTAATCGAAGGG
GTCGATGCCTTTTTCTTGTGTTTGCCAACCCCGCCAAATCGCGATGGCTCCTCGAATTTGAGCTACTATTTCGATGCTGT
CAATCATTTAGCGAAGTTGTTGGCTAAACGTGCTGATCAACGCCGCGTGGTGATTATCAATAAGAGCACAGTGCCAGTTG
GCACTGGCCGCCAACTTGAGGAAGTGCTCAAAAGCCATAATGTGCCAAACGTGGGGATTGCCTCGAACCCTGAATTTTTG
CCCGAAGGCAACGCGGTTGAAAAATCGCGCCATCCTGATCGGGTCGTGGTTGGGGCTGATACCGAGGAAGATTTCCGGAT
TTTGCGCCGGATCTACTCGCAATTTATCAACCATGTGCGAATTGCCTTTATCGAAACCACCCCTGAAACTGCTGAATCGA
TTAAGTATGTCGCCAATACCTTGTTGTTGACCTACATTTCATTCTGGAACGGGGTTGGCGGACGTTTGGCTGAATCGGTC
TCAAATGTGCGCATGGAAGATCTCAAGCGTGGCGTAACCGCCGATACCCGCATTAGCAAATGGGGTTCGTTCGTCTCGAA
CGGCGCTGGTGGCTCGTGCTTTGGCAAAGACATTCAATCGTTGATCTATCAACTTAAGAGCCGCAACCAAAGCACCGATT
TGCTCGAATCGGTCTATGAAATTAACGAATACCAAAAGACCTATTTGATCGATCGGGCAGCGGCCGAAGCTGGCGTGAAG
TTTAACAATAAAGTTGTGGCATTGTTGGGCTTGGCCTTCAAACAACGCACCAACGATATGCGCGATGCCTCAGCCTTGAA
AGTTGTCGAAAGCTTGCTTGGCCGTGGGGTCAAGGAAATTCGCGCCTACGACCCAATGGCCGAAGAAGAAGCCAAGCGCT
TTTTCAACCCCGAACACAACCACTTGTTCGAGCGCATTAGCTACCACCCTTCGGCCAAAGCAGCGCTCGAAGGCAGCGAT
ATGCTGTTTATCTCGACCGACTGGGAAGAATTCCGCGGACTTTCGAGCACCATTGAAAGCACCGTGCCAGCACCATACCT
GATCATCGATGGTCGCCGCATGATTCCCGACTACAATGAGTTGGTCGAACGCGGCTATAGCTATTTGGCGGTTGGCTCAC
CCTACTTGAACAAATAG

Upstream 100 bases:

>100_bases
GATGTTGGTCATTGTTCGCTGGTTCACATGGGACGGTGCCGTTTGTTATTAATGGTTGAGGTTGCTTCCACCGTCGAAGT
GGCCTACCGAAGGAGCTTGC

Downstream 100 bases:

>100_bases
CGATTATTGTTGCTTCAGCCGCCCTTGATTGGTTAAGATCAAGGGCGGTTGGTTGTTTTAGCTGGTTCCTTAACCAATAG
GTTTTTAACCAAGTATTGAA

Product: UDP-glucose/GDP-mannose dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKIVVAGTGFVGLPHAAVCSEYGHEVYAYDIDTKRIAAYKTAKREEIEKYVNEPGLASIIQENINRSLHFIDDLEPVIEG
VDAFFLCLPTPPNRDGSSNLSYYFDAVNHLAKLLAKRADQRRVVIINKSTVPVGTGRQLEEVLKSHNVPNVGIASNPEFL
PEGNAVEKSRHPDRVVVGADTEEDFRILRRIYSQFINHVRIAFIETTPETAESIKYVANTLLLTYISFWNGVGGRLAESV
SNVRMEDLKRGVTADTRISKWGSFVSNGAGGSCFGKDIQSLIYQLKSRNQSTDLLESVYEINEYQKTYLIDRAAAEAGVK
FNNKVVALLGLAFKQRTNDMRDASALKVVESLLGRGVKEIRAYDPMAEEEAKRFFNPEHNHLFERISYHPSAKAALEGSD
MLFISTDWEEFRGLSSTIESTVPAPYLIIDGRRMIPDYNELVERGYSYLAVGSPYLNK

Sequences:

>Translated_458_residues
MKIVVAGTGFVGLPHAAVCSEYGHEVYAYDIDTKRIAAYKTAKREEIEKYVNEPGLASIIQENINRSLHFIDDLEPVIEG
VDAFFLCLPTPPNRDGSSNLSYYFDAVNHLAKLLAKRADQRRVVIINKSTVPVGTGRQLEEVLKSHNVPNVGIASNPEFL
PEGNAVEKSRHPDRVVVGADTEEDFRILRRIYSQFINHVRIAFIETTPETAESIKYVANTLLLTYISFWNGVGGRLAESV
SNVRMEDLKRGVTADTRISKWGSFVSNGAGGSCFGKDIQSLIYQLKSRNQSTDLLESVYEINEYQKTYLIDRAAAEAGVK
FNNKVVALLGLAFKQRTNDMRDASALKVVESLLGRGVKEIRAYDPMAEEEAKRFFNPEHNHLFERISYHPSAKAALEGSD
MLFISTDWEEFRGLSSTIESTVPAPYLIIDGRRMIPDYNELVERGYSYLAVGSPYLNK
>Mature_458_residues
MKIVVAGTGFVGLPHAAVCSEYGHEVYAYDIDTKRIAAYKTAKREEIEKYVNEPGLASIIQENINRSLHFIDDLEPVIEG
VDAFFLCLPTPPNRDGSSNLSYYFDAVNHLAKLLAKRADQRRVVIINKSTVPVGTGRQLEEVLKSHNVPNVGIASNPEFL
PEGNAVEKSRHPDRVVVGADTEEDFRILRRIYSQFINHVRIAFIETTPETAESIKYVANTLLLTYISFWNGVGGRLAESV
SNVRMEDLKRGVTADTRISKWGSFVSNGAGGSCFGKDIQSLIYQLKSRNQSTDLLESVYEINEYQKTYLIDRAAAEAGVK
FNNKVVALLGLAFKQRTNDMRDASALKVVESLLGRGVKEIRAYDPMAEEEAKRFFNPEHNHLFERISYHPSAKAALEGSD
MLFISTDWEEFRGLSSTIESTVPAPYLIIDGRRMIPDYNELVERGYSYLAVGSPYLNK

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=471, Percent_Identity=27.1762208067941, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI296040438, Length=342, Percent_Identity=28.6549707602339, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI296040443, Length=325, Percent_Identity=28, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1788340, Length=376, Percent_Identity=27.3936170212766, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI48994968, Length=428, Percent_Identity=24.5327102803738, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17560350, Length=472, Percent_Identity=30.7203389830508, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI17136908, Length=477, Percent_Identity=29.559748427673, Blast_Score=177, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 51306; Mature: 51306

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVVAGTGFVGLPHAAVCSEYGHEVYAYDIDTKRIAAYKTAKREEIEKYVNEPGLASII
CEEEEECCCCCCCCHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
QENINRSLHFIDDLEPVIEGVDAFFLCLPTPPNRDGSSNLSYYFDAVNHLAKLLAKRADQ
HHHHCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
RRVVIINKSTVPVGTGRQLEEVLKSHNVPNVGIASNPEFLPEGNAVEKSRHPDRVVVGAD
CEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECC
TEEDFRILRRIYSQFINHVRIAFIETTPETAESIKYVANTLLLTYISFWNGVGGRLAESV
CHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SNVRMEDLKRGVTADTRISKWGSFVSNGAGGSCFGKDIQSLIYQLKSRNQSTDLLESVYE
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
INEYQKTYLIDRAAAEAGVKFNNKVVALLGLAFKQRTNDMRDASALKVVESLLGRGVKEI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHH
RAYDPMAEEEAKRFFNPEHNHLFERISYHPSAKAALEGSDMLFISTDWEEFRGLSSTIES
HHCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCEECCCCEEEEECCHHHHCCHHHHHHH
TVPAPYLIIDGRRMIPDYNELVERGYSYLAVGSPYLNK
CCCCCEEEECCCCCCCCHHHHHHCCCCEEEECCCCCCC
>Mature Secondary Structure
MKIVVAGTGFVGLPHAAVCSEYGHEVYAYDIDTKRIAAYKTAKREEIEKYVNEPGLASII
CEEEEECCCCCCCCHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
QENINRSLHFIDDLEPVIEGVDAFFLCLPTPPNRDGSSNLSYYFDAVNHLAKLLAKRADQ
HHHHCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
RRVVIINKSTVPVGTGRQLEEVLKSHNVPNVGIASNPEFLPEGNAVEKSRHPDRVVVGAD
CEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECC
TEEDFRILRRIYSQFINHVRIAFIETTPETAESIKYVANTLLLTYISFWNGVGGRLAESV
CHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SNVRMEDLKRGVTADTRISKWGSFVSNGAGGSCFGKDIQSLIYQLKSRNQSTDLLESVYE
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
INEYQKTYLIDRAAAEAGVKFNNKVVALLGLAFKQRTNDMRDASALKVVESLLGRGVKEI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHH
RAYDPMAEEEAKRFFNPEHNHLFERISYHPSAKAALEGSDMLFISTDWEEFRGLSSTIES
HHCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCEECCCCEEEEECCHHHHCCHHHHHHH
TVPAPYLIIDGRRMIPDYNELVERGYSYLAVGSPYLNK
CCCCCEEEECCCCCCCCHHHHHHCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]