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The map label for this gene is ccrMIM [H]

Identifier: 159899562

GI number: 159899562

Start: 3843996

End: 3845123

Strand: Reverse

Name: ccrMIM [H]

Synonym: Haur_3043

Alternate gene names: 159899562

Gene position: 3845123-3843996 (Counterclockwise)

Preceding gene: 159899563

Following gene: 159899561

Centisome position: 60.59

GC content: 48.23

Gene sequence:

>1128_bases
ATGGCCGATTTAACCTTGAACCACGATCAAATCCTTTTAGGTGATTGTCGTGATGTTCTTCCATTACTGCCACCAGCCAG
CGTTGACCTCATTTTCGCTGACCCGCCCTATAATTTGCAATTGCGTGGCGATTTATTACGCCCCAACATGACGCATGTTG
ATGCAGTTGATGATGATTGGGACTCATTTCGTGATTTTGCTGCCTATGATGCGTTTACACGTGCTTGGCTGCAAGCATGT
CAGCGTGTTTTAAAAGATAATGGCACAATGTGGGTGATTGGTAGTTATCACAATATCTATCGGGTTGGTACAATTTTACA
AGACCTTGGCTTTTGGATTTTAAACGATATTGTTTGGATTAAGCGTAATCCAATGCCAAATTTTCGTGGTGTACGCCTAA
CCAATGCCCATGAGACATTAATTTGGTGTGCGAAATTGCCAGGCCAGAAGTATACCTTTAATTATCATGCCTTGCGCCAT
TTGAACGACGATAAGCAAATGCGCAGCGATTGGGAATTTCCGCTGTGTACTGGCAACGAACGCCTGCGGATCAACGGCAA
CAAAGTGCATAGCACCCAAAAGCCCGAAGCGTTGCTCTATCGAGTATTATTGGCAAGCTCGAATGTTGGTGATGTGGTGC
TTGATCCATTTTTTGGCACGGGCACGACGGGCGCGGTAGCCAAACGTTTGGCGCGTCACTACATTGGCATCGAGCGTGAT
CCCAGCTATGTTGAAGCAGCGCGAGGCCGGATTGCCGCGATTGAGTCGCCTAGCAGCACCGATGCCCTGCAAGCCTTGCC
AAGCAACAAACGGCGGATTCCACGGATTCCGTTTGGCAATTTGTTGGAGCATGGCTTGTTGCAAGCGGGCCAACAATTAT
GGTTTAACCGCGATCCAAACTTGGTTGCCACGCTGTTGGCTGATGCTTCGCTGCGCATGTCCGATGGCACACGCGGATCG
ATTCACAAGCTTGGTACAATTTTGACAGGCCAACCAAGTTGCAATGGCTGGGAACATTGGTTTTTTCAGGCGAGTGATGG
TACTTTAACTTCGATTGATGTGTTGCGCCAAGAGGTGCGGCGTTTACGCGAACAAACTCCAAGCGCCGATGATTTAAGTG
AGTTATGA

Upstream 100 bases:

>100_bases
GCTCACACCTGAATTAGGCCCATGCTAACGATTTAGCATATTCCACATGCATTGATTCTTTGGTAGGATACGATCTTACT
ATCACGCATGAGGACTGCTT

Downstream 100 bases:

>100_bases
CGAACAATCTTGCTGAGGCAGTTCGAGCACAGGCTGCTCAATTAGGTTTTAATCTGGTCGGTATCACGCCTGCCAAGCCA
TCACCAACTTTAGCTGCTTA

Product: DNA methylase N-4/N-6 domain-containing protein

Products: NA

Alternate protein names: M.CcrMI; Adenine-specific methyltransferase CcrMI [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MADLTLNHDQILLGDCRDVLPLLPPASVDLIFADPPYNLQLRGDLLRPNMTHVDAVDDDWDSFRDFAAYDAFTRAWLQAC
QRVLKDNGTMWVIGSYHNIYRVGTILQDLGFWILNDIVWIKRNPMPNFRGVRLTNAHETLIWCAKLPGQKYTFNYHALRH
LNDDKQMRSDWEFPLCTGNERLRINGNKVHSTQKPEALLYRVLLASSNVGDVVLDPFFGTGTTGAVAKRLARHYIGIERD
PSYVEAARGRIAAIESPSSTDALQALPSNKRRIPRIPFGNLLEHGLLQAGQQLWFNRDPNLVATLLADASLRMSDGTRGS
IHKLGTILTGQPSCNGWEHWFFQASDGTLTSIDVLRQEVRRLREQTPSADDLSEL

Sequences:

>Translated_375_residues
MADLTLNHDQILLGDCRDVLPLLPPASVDLIFADPPYNLQLRGDLLRPNMTHVDAVDDDWDSFRDFAAYDAFTRAWLQAC
QRVLKDNGTMWVIGSYHNIYRVGTILQDLGFWILNDIVWIKRNPMPNFRGVRLTNAHETLIWCAKLPGQKYTFNYHALRH
LNDDKQMRSDWEFPLCTGNERLRINGNKVHSTQKPEALLYRVLLASSNVGDVVLDPFFGTGTTGAVAKRLARHYIGIERD
PSYVEAARGRIAAIESPSSTDALQALPSNKRRIPRIPFGNLLEHGLLQAGQQLWFNRDPNLVATLLADASLRMSDGTRGS
IHKLGTILTGQPSCNGWEHWFFQASDGTLTSIDVLRQEVRRLREQTPSADDLSEL
>Mature_374_residues
ADLTLNHDQILLGDCRDVLPLLPPASVDLIFADPPYNLQLRGDLLRPNMTHVDAVDDDWDSFRDFAAYDAFTRAWLQACQ
RVLKDNGTMWVIGSYHNIYRVGTILQDLGFWILNDIVWIKRNPMPNFRGVRLTNAHETLIWCAKLPGQKYTFNYHALRHL
NDDKQMRSDWEFPLCTGNERLRINGNKVHSTQKPEALLYRVLLASSNVGDVVLDPFFGTGTTGAVAKRLARHYIGIERDP
SYVEAARGRIAAIESPSSTDALQALPSNKRRIPRIPFGNLLEHGLLQAGQQLWFNRDPNLVATLLADASLRMSDGTRGSI
HKLGTILTGQPSCNGWEHWFFQASDGTLTSIDVLRQEVRRLREQTPSADDLSEL

Specific function: This methylase recognizes the double-stranded sequence GANTC and causes specific methylation on A-2 on both strands. Ccrm-mediated methylation has important cellular functions. Appears to contribute to the accurate cell-cycle control of DNA replication an

COG id: COG0863

COG function: function code L; DNA modification methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI87082238, Length=267, Percent_Identity=32.9588014981273, Blast_Score=108, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002941
- InterPro:   IPR002052
- InterPro:   IPR001091 [H]

Pfam domain/function: PF01555 N6_N4_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 42398; Mature: 42266

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLTLNHDQILLGDCRDVLPLLPPASVDLIFADPPYNLQLRGDLLRPNMTHVDAVDDDW
CCCEECCCCEEEECCHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCH
DSFRDFAAYDAFTRAWLQACQRVLKDNGTMWVIGSYHNIYRVGTILQDLGFWILNDIVWI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCEEEE
KRNPMPNFRGVRLTNAHETLIWCAKLPGQKYTFNYHALRHLNDDKQMRSDWEFPLCTGNE
ECCCCCCCCCEEEECCCCEEEEEECCCCCEEEEEHHHHHHCCCHHHHHCCCCCCEECCCC
RLRINGNKVHSTQKPEALLYRVLLASSNVGDVVLDPFFGTGTTGAVAKRLARHYIGIERD
EEEECCCEECCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCC
PSYVEAARGRIAAIESPSSTDALQALPSNKRRIPRIPFGNLLEHGLLQAGQQLWFNRDPN
CHHHHHHCCCEEEECCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
LVATLLADASLRMSDGTRGSIHKLGTILTGQPSCNGWEHWFFQASDGTLTSIDVLRQEVR
HHHHHHHCCCEEECCCCCCCHHHHCEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
RLREQTPSADDLSEL
HHHHHCCCCCHHHCC
>Mature Secondary Structure 
ADLTLNHDQILLGDCRDVLPLLPPASVDLIFADPPYNLQLRGDLLRPNMTHVDAVDDDW
CCEECCCCEEEECCHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCH
DSFRDFAAYDAFTRAWLQACQRVLKDNGTMWVIGSYHNIYRVGTILQDLGFWILNDIVWI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCEEEE
KRNPMPNFRGVRLTNAHETLIWCAKLPGQKYTFNYHALRHLNDDKQMRSDWEFPLCTGNE
ECCCCCCCCCEEEECCCCEEEEEECCCCCEEEEEHHHHHHCCCHHHHHCCCCCCEECCCC
RLRINGNKVHSTQKPEALLYRVLLASSNVGDVVLDPFFGTGTTGAVAKRLARHYIGIERD
EEEECCCEECCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCC
PSYVEAARGRIAAIESPSSTDALQALPSNKRRIPRIPFGNLLEHGLLQAGQQLWFNRDPN
CHHHHHHCCCEEEECCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
LVATLLADASLRMSDGTRGSIHKLGTILTGQPSCNGWEHWFFQASDGTLTSIDVLRQEVR
HHHHHHHCCCEEECCCCCCCHHHHCEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
RLREQTPSADDLSEL
HHHHHCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8289276 [H]