Click here to switch to the map view.

The map label for this gene is rsbRA [H]

Identifier: 159899472

GI number: 159899472

Start: 3726676

End: 3728325

Strand: Reverse

Name: rsbRA [H]

Synonym: Haur_2953

Alternate gene names: 159899472

Gene position: 3728325-3726676 (Counterclockwise)

Preceding gene: 159899473

Following gene: 159899471

Centisome position: 58.75

GC content: 50.12

Gene sequence:

>1650_bases
ATGGGGACTGATGTGTATGTGGAACGGGATGAAACGACGATTGACCAGCAACAAACCATCATCAACTTGCGTGCCCAGAT
CGCGATCTACGAACAGATTTTAGATAGTATCCCCGATTTGATTTTATACAAAGGCCCAGGTTCGCATATTCGCTACGCCA
ATCGCGCTTTTCGCGAATACTATGGCATGGATAGCCAGCAGCTGCAAGATCTGATCGACGCAGATTTTAACCAACCAAGT
TATACCGAGCAATATATTCGCGATGATGCTCAGGTGTTTCAAACTGGCCAAGCCTTGGTGATCGATTCAGAGCCAGTTAC
GCGCCATACCGGTGAAGTGCATCTGTTTGCCACCACCAAACATCCCATTCGCAATCACGATGGCTCGATCATCGGCACGG
TTGGCATTTCGCGTGATCTGAGCAACGAGGTAGCGGCCTCGGCAGCCCTAACCGATAACGAGGCTCGCTTGCAACGGATC
ATCGAAAATGTACCAGGCATGGTCTATCAATTTTTGCTTGAGCCAGATCATACGATGCGTTTTCCATTTGTCAGCACTGG
CAGCCGCGATATTTATGGCCTCGAACCAGAAGCGATTATGCAAAATGCCAGCATCGTGACCGAGGCCGTCAATCCAGCTG
ACCGACTGCGCTTTCAAGAGGCGATTATGACTTCGGCTCAAACGCTTGAGCCATGGCGCTGGGAAGGTCGGGTTTATATC
AATGGCCAAGAAAACTGGCTGCAAGGGGCTTCTCGGCCCACGAAATTGGCCAATGGAGCCATTTTATGGGATGGTTTGCT
ATTAAATATTACCCAACAAAAACAAGCTGAAGCCTTGTTGGGGCGTTTTGATACCATTCTAAGTTCGACCCCGGACTTGG
TAGCGATTGCCGATTTGTCAGGCCAGATGCAATATTTGAATCCGGCGGCGCGGCGCTTGTTGCAACTTGAGCCAACCGAT
CAGGTCAGTCAATTAACCTGGCACGATTTACACCCCAACCAAGCTGAGCAAACATGGCTAGCCAAAACCTTGCAGCATGC
CCAAATCCATGGCTCGTGGATGGGCGAGCATCAACTACAAACGGCTCAAGGCCAAAAGCTCCCTGTGATGTATCAAATGC
TCTGTCATTATGATATTGATCACCAACCCAGCTTCTTCTCGATGATCGCCCATGATATTAGCGACCAAAAACAGGCTGAA
GCTGAACGCCAACGCTTGCACGAAGAAGTTATTCGCACCCAACAACAAGCCTTGATCGAGCTTTCTACCCCGCTGATTCC
GATTGCCGACACGGTGGTGCTCTTGCCGTTAGTTGGCAGCGTTGATACCGCGCGGGCACAGCAATTTATGGAAACCTTGC
TCGAAGGTGTGCATATCAATAAAGCTCAAATCGCAATTGTCGATGTGACGGGCGTTCCAGTGATGGATACCCAAGTGGCA
GGCCTGTTGATTCGTGCCGCAACCAGCGTCCAGCTACTAGGAGCACGCGTAATCATTACTGGCATTCGGCCAGAATTGGC
GCAAACCTTGGTTACCTTGGGGGTTGATTTCCGCTCGATCATGACGCATAGTAGCCTGCAACAAGGAATTACCTATGCGA
TCAATGCGACCCGTGGGCAGCAAATGAATGTTAGGTATCGCGGAAATTGA

Upstream 100 bases:

>100_bases
AGAAGTACTAGATAAGATCGTGACCTTTGTGGGAGGCGCAGGGTAGCCCACATGGGGGACACTAAAGTAATTACAAAAAA
ATAAATCGAGGAGGCACGTA

Downstream 100 bases:

>100_bases
TCGATAGGCGGCAAAGGGAGCGATCATGACCATCCTGCATTCGCTGGGCGATATTTCGTTGGCTTGGCTGACCGAACACT
TACAGCCTTGGTTGGGTTCA

Product: putative PAS/PAC sensor protein

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MGTDVYVERDETTIDQQQTIINLRAQIAIYEQILDSIPDLILYKGPGSHIRYANRAFREYYGMDSQQLQDLIDADFNQPS
YTEQYIRDDAQVFQTGQALVIDSEPVTRHTGEVHLFATTKHPIRNHDGSIIGTVGISRDLSNEVAASAALTDNEARLQRI
IENVPGMVYQFLLEPDHTMRFPFVSTGSRDIYGLEPEAIMQNASIVTEAVNPADRLRFQEAIMTSAQTLEPWRWEGRVYI
NGQENWLQGASRPTKLANGAILWDGLLLNITQQKQAEALLGRFDTILSSTPDLVAIADLSGQMQYLNPAARRLLQLEPTD
QVSQLTWHDLHPNQAEQTWLAKTLQHAQIHGSWMGEHQLQTAQGQKLPVMYQMLCHYDIDHQPSFFSMIAHDISDQKQAE
AERQRLHEEVIRTQQQALIELSTPLIPIADTVVLLPLVGSVDTARAQQFMETLLEGVHINKAQIAIVDVTGVPVMDTQVA
GLLIRAATSVQLLGARVIITGIRPELAQTLVTLGVDFRSIMTHSSLQQGITYAINATRGQQMNVRYRGN

Sequences:

>Translated_549_residues
MGTDVYVERDETTIDQQQTIINLRAQIAIYEQILDSIPDLILYKGPGSHIRYANRAFREYYGMDSQQLQDLIDADFNQPS
YTEQYIRDDAQVFQTGQALVIDSEPVTRHTGEVHLFATTKHPIRNHDGSIIGTVGISRDLSNEVAASAALTDNEARLQRI
IENVPGMVYQFLLEPDHTMRFPFVSTGSRDIYGLEPEAIMQNASIVTEAVNPADRLRFQEAIMTSAQTLEPWRWEGRVYI
NGQENWLQGASRPTKLANGAILWDGLLLNITQQKQAEALLGRFDTILSSTPDLVAIADLSGQMQYLNPAARRLLQLEPTD
QVSQLTWHDLHPNQAEQTWLAKTLQHAQIHGSWMGEHQLQTAQGQKLPVMYQMLCHYDIDHQPSFFSMIAHDISDQKQAE
AERQRLHEEVIRTQQQALIELSTPLIPIADTVVLLPLVGSVDTARAQQFMETLLEGVHINKAQIAIVDVTGVPVMDTQVA
GLLIRAATSVQLLGARVIITGIRPELAQTLVTLGVDFRSIMTHSSLQQGITYAINATRGQQMNVRYRGN
>Mature_548_residues
GTDVYVERDETTIDQQQTIINLRAQIAIYEQILDSIPDLILYKGPGSHIRYANRAFREYYGMDSQQLQDLIDADFNQPSY
TEQYIRDDAQVFQTGQALVIDSEPVTRHTGEVHLFATTKHPIRNHDGSIIGTVGISRDLSNEVAASAALTDNEARLQRII
ENVPGMVYQFLLEPDHTMRFPFVSTGSRDIYGLEPEAIMQNASIVTEAVNPADRLRFQEAIMTSAQTLEPWRWEGRVYIN
GQENWLQGASRPTKLANGAILWDGLLLNITQQKQAEALLGRFDTILSSTPDLVAIADLSGQMQYLNPAARRLLQLEPTDQ
VSQLTWHDLHPNQAEQTWLAKTLQHAQIHGSWMGEHQLQTAQGQKLPVMYQMLCHYDIDHQPSFFSMIAHDISDQKQAEA
ERQRLHEEVIRTQQQALIELSTPLIPIADTVVLLPLVGSVDTARAQQFMETLLEGVHINKAQIAIVDVTGVPVMDTQVAG
LLIRAATSVQLLGARVIITGIRPELAQTLVTLGVDFRSIMTHSSLQQGITYAINATRGQQMNVRYRGN

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 61572; Mature: 61440

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50112 PAS ; PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTDVYVERDETTIDQQQTIINLRAQIAIYEQILDSIPDLILYKGPGSHIRYANRAFREY
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHH
YGMDSQQLQDLIDADFNQPSYTEQYIRDDAQVFQTGQALVIDSEPVTRHTGEVHLFATTK
HCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEEEECC
HPIRNHDGSIIGTVGISRDLSNEVAASAALTDNEARLQRIIENVPGMVYQFLLEPDHTMR
CCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHCCCCCCEE
FPFVSTGSRDIYGLEPEAIMQNASIVTEAVNPADRLRFQEAIMTSAQTLEPWRWEGRVYI
CCEEECCCCCEECCCHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEECCEEEE
NGQENWLQGASRPTKLANGAILWDGLLLNITQQKQAEALLGRFDTILSSTPDLVAIADLS
CCCHHHHCCCCCCCHHCCCEEEECCEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEECCC
GQMQYLNPAARRLLQLEPTDQVSQLTWHDLHPNQAEQTWLAKTLQHAQIHGSWMGEHQLQ
CCHHHCCHHHHHHEECCCCCHHHHCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHH
TAQGQKLPVMYQMLCHYDIDHQPSFFSMIAHDISDQKQAEAERQRLHEEVIRTQQQALIE
HCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
LSTPLIPIADTVVLLPLVGSVDTARAQQFMETLLEGVHINKAQIAIVDVTGVPVMDTQVA
HCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEHHHHH
GLLIRAATSVQLLGARVIITGIRPELAQTLVTLGVDFRSIMTHSSLQQGITYAINATRGQ
HHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCC
QMNVRYRGN
EEEEEECCC
>Mature Secondary Structure 
GTDVYVERDETTIDQQQTIINLRAQIAIYEQILDSIPDLILYKGPGSHIRYANRAFREY
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHH
YGMDSQQLQDLIDADFNQPSYTEQYIRDDAQVFQTGQALVIDSEPVTRHTGEVHLFATTK
HCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEEEECC
HPIRNHDGSIIGTVGISRDLSNEVAASAALTDNEARLQRIIENVPGMVYQFLLEPDHTMR
CCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHCCCCCCEE
FPFVSTGSRDIYGLEPEAIMQNASIVTEAVNPADRLRFQEAIMTSAQTLEPWRWEGRVYI
CCEEECCCCCEECCCHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEECCEEEE
NGQENWLQGASRPTKLANGAILWDGLLLNITQQKQAEALLGRFDTILSSTPDLVAIADLS
CCCHHHHCCCCCCCHHCCCEEEECCEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEECCC
GQMQYLNPAARRLLQLEPTDQVSQLTWHDLHPNQAEQTWLAKTLQHAQIHGSWMGEHQLQ
CCHHHCCHHHHHHEECCCCCHHHHCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHH
TAQGQKLPVMYQMLCHYDIDHQPSFFSMIAHDISDQKQAEAERQRLHEEVIRTQQQALIE
HCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
LSTPLIPIADTVVLLPLVGSVDTARAQQFMETLLEGVHINKAQIAIVDVTGVPVMDTQVA
HCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEHHHHH
GLLIRAATSVQLLGARVIITGIRPELAQTLVTLGVDFRSIMTHSSLQQGITYAINATRGQ
HHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCC
QMNVRYRGN
EEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]