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The map label for this gene is yfhM [H]

Identifier: 159899392

GI number: 159899392

Start: 3645325

End: 3646269

Strand: Reverse

Name: yfhM [H]

Synonym: Haur_2873

Alternate gene names: 159899392

Gene position: 3646269-3645325 (Counterclockwise)

Preceding gene: 159899399

Following gene: 159899375

Centisome position: 57.45

GC content: 49.95

Gene sequence:

>945_bases
ATGACGATGGTTAATGCAACCGATTTTCCTAAACCCAGCTTTATTTCCGTTAATGGCGTAGACCTCGAAGTCTTTGAAGC
GGGCCAACCCCATGGCGGCAAACCGATAGTTCTCTGTCATGGCTGGCCTGAGCATGCCTTTTCTTGGCGCTATCAAATGG
CTGCCCTTGCCGCCGCCGGCTACCATGTTATCGTCCCAAACCAGCGGGGCTACGGCAACTCATCGCGCCCAACTGATGTA
AGCGCCTATGATATTCAACATTTATCGGGTGATCTGATTGCGCTGCTTGATCACTATGGATATGCCAATGCCACCTTTGT
CGGCCATGATTGGGGGGCAATGGTCGTTTGGGGTTTGACCTTGTTGCATCCCACGCGGGTCAACAAGGTGATTAATCTGA
GTGTTCCCTATATTGAGCGCGGCGAAAAGCCTTGGATCGAGGTTATGGAGGCCGTGTTTGGCGACGATTTCTATTTCGTG
CATTTCAATCGCCAGCCAGGCGTGGCAGATGCCGTATTTGATGCTAATCGTTTCCAGTTTCTTCGCAACATGTATCGAAA
GAATGTCCCTCCTGCCGAGCCGCAGCCAGGGATGGCATTGATCAATCTTGCCAAAATCGCAGTACCACTTGGTGAGCCAA
TCATGAGCGAGAGCGAACTGGACGTTTTCGTCTCGGCCTTCGCCGCATCAGGGTTTACGGGTGGCATCAATTGGTATCGC
AATCTTGACCGTAATTGGCATTTGTTGGCCGATGTAAATCCAATTATCCAGCAGCCGACTCTCATGATTTATGGTGACCG
AGATTCTGTTCAGAAGTCGCAAACTCTGACAACCTTCGTGCCTAATGTAGAAGTTGTCAATCTGGATTGTGGTCATTGGA
TTCAACAAGAAATGCCTGAAGAGACAACCAAAGCCATCTTGGAATGGCTAGAACAGCACGCATAG

Upstream 100 bases:

>100_bases
CAAACAGGCGGTTGAGATTTTGGCTAACAAACTGCCGAACCAACAACAGCACAACCCATGCTCTGCCGAATTTTTGAAGC
AACCAATAGCGAAGGAAACA

Downstream 100 bases:

>100_bases
AGAATAGATCCTATGTGGCATTAGATTGACAGTGATTAATTCCCCCTCACCCCCTCGCCCGCACGCGAGGCGAGGGTGAA
CCATCCCTAGTATGAAATGG

Product: alpha/beta hydrolase fold-domain containing protein

Products: glycol

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTMVNATDFPKPSFISVNGVDLEVFEAGQPHGGKPIVLCHGWPEHAFSWRYQMAALAAAGYHVIVPNQRGYGNSSRPTDV
SAYDIQHLSGDLIALLDHYGYANATFVGHDWGAMVVWGLTLLHPTRVNKVINLSVPYIERGEKPWIEVMEAVFGDDFYFV
HFNRQPGVADAVFDANRFQFLRNMYRKNVPPAEPQPGMALINLAKIAVPLGEPIMSESELDVFVSAFAASGFTGGINWYR
NLDRNWHLLADVNPIIQQPTLMIYGDRDSVQKSQTLTTFVPNVEVVNLDCGHWIQQEMPEETTKAILEWLEQHA

Sequences:

>Translated_314_residues
MTMVNATDFPKPSFISVNGVDLEVFEAGQPHGGKPIVLCHGWPEHAFSWRYQMAALAAAGYHVIVPNQRGYGNSSRPTDV
SAYDIQHLSGDLIALLDHYGYANATFVGHDWGAMVVWGLTLLHPTRVNKVINLSVPYIERGEKPWIEVMEAVFGDDFYFV
HFNRQPGVADAVFDANRFQFLRNMYRKNVPPAEPQPGMALINLAKIAVPLGEPIMSESELDVFVSAFAASGFTGGINWYR
NLDRNWHLLADVNPIIQQPTLMIYGDRDSVQKSQTLTTFVPNVEVVNLDCGHWIQQEMPEETTKAILEWLEQHA
>Mature_313_residues
TMVNATDFPKPSFISVNGVDLEVFEAGQPHGGKPIVLCHGWPEHAFSWRYQMAALAAAGYHVIVPNQRGYGNSSRPTDVS
AYDIQHLSGDLIALLDHYGYANATFVGHDWGAMVVWGLTLLHPTRVNKVINLSVPYIERGEKPWIEVMEAVFGDDFYFVH
FNRQPGVADAVFDANRFQFLRNMYRKNVPPAEPQPGMALINLAKIAVPLGEPIMSESELDVFVSAFAASGFTGGINWYRN
LDRNWHLLADVNPIIQQPTLMIYGDRDSVQKSQTLTTFVPNVEVVNLDCGHWIQQEMPEETTKAILEWLEQHA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=330, Percent_Identity=32.4242424242424, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI218777840, Length=307, Percent_Identity=27.6872964169381, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI13376164, Length=307, Percent_Identity=27.6872964169381, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI218777837, Length=305, Percent_Identity=24.9180327868852, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17554012, Length=311, Percent_Identity=25.4019292604502, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17562298, Length=294, Percent_Identity=23.8095238095238, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.3.2.3

Molecular weight: Translated: 35225; Mature: 35094

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMVNATDFPKPSFISVNGVDLEVFEAGQPHGGKPIVLCHGWPEHAFSWRYQMAALAAAG
CCCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCC
YHVIVPNQRGYGNSSRPTDVSAYDIQHLSGDLIALLDHYGYANATFVGHDWGAMVVWGLT
EEEEECCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHH
LLHPTRVNKVINLSVPYIERGEKPWIEVMEAVFGDDFYFVHFNRQPGVADAVFDANRFQF
HCCHHHHCEEEEEECCHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHCCHHHHH
LRNMYRKNVPPAEPQPGMALINLAKIAVPLGEPIMSESELDVFVSAFAASGFTGGINWYR
HHHHHHCCCCCCCCCCCHHHEEHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHH
NLDRNWHLLADVNPIIQQPTLMIYGDRDSVQKSQTLTTFVPNVEVVNLDCGHWIQQEMPE
CCCCCEEEEECCCHHHCCCEEEEECCCHHHHHHCCEEEECCCEEEEEECCCHHHHHHCCH
ETTKAILEWLEQHA
HHHHHHHHHHHHCC
>Mature Secondary Structure 
TMVNATDFPKPSFISVNGVDLEVFEAGQPHGGKPIVLCHGWPEHAFSWRYQMAALAAAG
CCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCC
YHVIVPNQRGYGNSSRPTDVSAYDIQHLSGDLIALLDHYGYANATFVGHDWGAMVVWGLT
EEEEECCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHH
LLHPTRVNKVINLSVPYIERGEKPWIEVMEAVFGDDFYFVHFNRQPGVADAVFDANRFQF
HCCHHHHCEEEEEECCHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHCCHHHHH
LRNMYRKNVPPAEPQPGMALINLAKIAVPLGEPIMSESELDVFVSAFAASGFTGGINWYR
HHHHHHCCCCCCCCCCCHHHEEHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHH
NLDRNWHLLADVNPIIQQPTLMIYGDRDSVQKSQTLTTFVPNVEVVNLDCGHWIQQEMPE
CCCCCEEEEECCCHHHCCCEEEEECCCHHHHHHCCEEEECCCEEEEEECCCHHHHHHCCH
ETTKAILEWLEQHA
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; epoxide

Specific reaction: H2O + an epoxide = a glycol

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]