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The map label for this gene is yxeN [H]

Identifier: 159899278

GI number: 159899278

Start: 3513278

End: 3514087

Strand: Reverse

Name: yxeN [H]

Synonym: Haur_2759

Alternate gene names: 159899278

Gene position: 3514087-3513278 (Counterclockwise)

Preceding gene: 159899279

Following gene: 159899277

Centisome position: 55.37

GC content: 47.65

Gene sequence:

>810_bases
ATGGCTGCCGACCTTCCGCCTTCAACCTCGCTGCAACCCCCAACCAATAAACGTCTTGATTGGCGCACAATCCCATGGTG
GCTGGTCGCAATTGGCCTGATCATCGCCTTTATGGGCTTTCGGATTATCAGCGACCCGGAATATACCCGCATTTTCGAGA
CGATTCTGACCGGACTTGGCACAACCTTGATGGTCACAGGTATTTCATTTATTTGTGCATTAATTTTAGGTTTGGTGCTG
GGGTTGGGGCGCGTTTCACGCAACTTAATCTTGCGCAATCTCTCAATTGGCTATATTGAGTTTATTCGTGGCGTGCCAAT
TTTGGTGCTGATTTTTACCATCTCATTTGCAATTGTGCCAGCGTTATCCGATTGGATCACGATAAACGGCCAGAAACTGA
CTGTTTCGTTAACTGCCCGTGCGATTATTGCACTGGTGTTAATTTACGCGGCCTATATTGCCGAAATCTTCCGCGCTGGG
ATCGAATCGATCAGTCGTGGCCAGATGGAAGCCGCACGATCATTAGGCATGACCCATGGGCAAGCGATGCGCTATGTGAT
TTTGCCGCAAGCATTTCGCAATGTGCTGCCAGCCTTAGGCAACGATCTGATCGCGATTCTCAAAGATTCATCGTTGGTAT
CGGTATTGGGTGTGCGCGAAATTACCCAAGTTTCACGGCTTTCGGTTAGCTCGTCGTTTAAATATGAAGAAACCTATTTT
ATTCTGACCGCCTTCTATTTGACCATGACTTTAGTGCTGTCATTGCTGCTGCAATGGTTGCAACGAAAGATGAGCAGCAA
TGTCCACTAA

Upstream 100 bases:

>100_bases
AATTGCCCGAATAAGCTCATCAATTCAGTGGTGTGGTGCATTGAGGCGCTACACCACTGGGTTTATTCCATCCTCTCCTT
AGGCATCACAAGGAGTTCCC

Downstream 100 bases:

>100_bases
ACTTGCCAATTCCAATCAACCAATGATTAGCATTAACAAGGTCAGCAAGTTTTTTGGCGATTTTCGCGCCTTGGATGAGG
TCAGTCTGACGGTTGATCGC

Product: polar amino acid ABC transporter inner membrane subunit

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MAADLPPSTSLQPPTNKRLDWRTIPWWLVAIGLIIAFMGFRIISDPEYTRIFETILTGLGTTLMVTGISFICALILGLVL
GLGRVSRNLILRNLSIGYIEFIRGVPILVLIFTISFAIVPALSDWITINGQKLTVSLTARAIIALVLIYAAYIAEIFRAG
IESISRGQMEAARSLGMTHGQAMRYVILPQAFRNVLPALGNDLIAILKDSSLVSVLGVREITQVSRLSVSSSFKYEETYF
ILTAFYLTMTLVLSLLLQWLQRKMSSNVH

Sequences:

>Translated_269_residues
MAADLPPSTSLQPPTNKRLDWRTIPWWLVAIGLIIAFMGFRIISDPEYTRIFETILTGLGTTLMVTGISFICALILGLVL
GLGRVSRNLILRNLSIGYIEFIRGVPILVLIFTISFAIVPALSDWITINGQKLTVSLTARAIIALVLIYAAYIAEIFRAG
IESISRGQMEAARSLGMTHGQAMRYVILPQAFRNVLPALGNDLIAILKDSSLVSVLGVREITQVSRLSVSSSFKYEETYF
ILTAFYLTMTLVLSLLLQWLQRKMSSNVH
>Mature_268_residues
AADLPPSTSLQPPTNKRLDWRTIPWWLVAIGLIIAFMGFRIISDPEYTRIFETILTGLGTTLMVTGISFICALILGLVLG
LGRVSRNLILRNLSIGYIEFIRGVPILVLIFTISFAIVPALSDWITINGQKLTVSLTARAIIALVLIYAAYIAEIFRAGI
ESISRGQMEAARSLGMTHGQAMRYVILPQAFRNVLPALGNDLIAILKDSSLVSVLGVREITQVSRLSVSSSFKYEETYFI
LTAFYLTMTLVLSLLLQWLQRKMSSNVH

Specific function: Probably part of the ABC transporter complex yxeMNO that could be involved in amino-acid import. May transport S- methylcysteine. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787030, Length=211, Percent_Identity=35.5450236966825, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI87082239, Length=213, Percent_Identity=32.8638497652582, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1788646, Length=218, Percent_Identity=33.9449541284404, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788226, Length=211, Percent_Identity=35.0710900473934, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1786873, Length=209, Percent_Identity=33.4928229665072, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786874, Length=209, Percent_Identity=30.622009569378, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787087, Length=220, Percent_Identity=28.1818181818182, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI48994930, Length=209, Percent_Identity=32.0574162679426, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788645, Length=226, Percent_Identity=28.7610619469027, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787086, Length=220, Percent_Identity=29.5454545454545, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29823; Mature: 29692

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAADLPPSTSLQPPTNKRLDWRTIPWWLVAIGLIIAFMGFRIISDPEYTRIFETILTGLG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TTLMVTGISFICALILGLVLGLGRVSRNLILRNLSIGYIEFIRGVPILVLIFTISFAIVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHH
ALSDWITINGQKLTVSLTARAIIALVLIYAAYIAEIFRAGIESISRGQMEAARSLGMTHG
HHHHHEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QAMRYVILPQAFRNVLPALGNDLIAILKDSSLVSVLGVREITQVSRLSVSSSFKYEETYF
HHHHHEECHHHHHHHHHHHCCCCEEHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ILTAFYLTMTLVLSLLLQWLQRKMSSNVH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AADLPPSTSLQPPTNKRLDWRTIPWWLVAIGLIIAFMGFRIISDPEYTRIFETILTGLG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TTLMVTGISFICALILGLVLGLGRVSRNLILRNLSIGYIEFIRGVPILVLIFTISFAIVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHH
ALSDWITINGQKLTVSLTARAIIALVLIYAAYIAEIFRAGIESISRGQMEAARSLGMTHG
HHHHHEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QAMRYVILPQAFRNVLPALGNDLIAILKDSSLVSVLGVREITQVSRLSVSSSFKYEETYF
HHHHHEECHHHHHHHHHHHCCCCEEHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ILTAFYLTMTLVLSLLLQWLQRKMSSNVH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8867804; 9384377 [H]