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The map label for this gene is rsbRB [H]

Identifier: 159899259

GI number: 159899259

Start: 3496345

End: 3497268

Strand: Reverse

Name: rsbRB [H]

Synonym: Haur_2740

Alternate gene names: 159899259

Gene position: 3497268-3496345 (Counterclockwise)

Preceding gene: 159899260

Following gene: 159899250

Centisome position: 55.1

GC content: 49.78

Gene sequence:

>924_bases
ATGACAGCCTATGAAAGTAGCCGCCATCATCAGCCAGTTGAGCAAACGATTCTGGCGATTCATGAATTGATTCGGGCGAT
TTTGCTGCCGCGTGATTTGGCTGATGTTTGTCGAACAATTTTTGAGCAATTGCATCACGTGTTGCGTTTTGATGCTGGCT
TTATCGAGCAATATCAGCCCAAAACCGACACCATGCAAACGATCTACTCGATTGATGAGGGCATTGAAAACGTTGTGCCC
TATGCTTGGGATTATCGGCGCTCAAAGGTCGTAACTTGGATTATTGCCAACCAGCAATTGGTGCGCTTTGATGATTTGCA
TGAAGATTTGCCCAAACGCTTTACCGTGGAAAACACTCGCAGCTTTGGTCAAGAAGAGAAACGTTCACGCGCCTGGATGA
GCGTGCCCTTGCTGATTGGCACTGATTTTGTGGGCGTGTTGAATATTCAGAGCTATCAGCCTGCCTTGTATGGCGAGTTT
GAAGAAGCCTTGTTGAGCACGGTCGCCAGTTCGGTGGCTTTGGCGCTCGATAATGCCCAAGTTTTGGCTGAGCTAGAGCT
AGAAGTCAGCGAACTCGATATTCCGCGCATCCCACTTTCCGATGATGTATTGATTGTGCCCTTGATTGGGGTGCTTGATC
GGCTGCGCTGGGAAAACCTGACCCATACGATTCTTGAAACCTTGCGCGAGCGTGGCTGTGAACATGTGCTGCTCGATGGC
AGTGGCTTATTAACCTTCGATCCCGATGCGATCCAAGCGATTAGTACGATTGTTAAAGCGATTGAATTGATCGGGGCCAA
AAGCATGCTGATTGGCCTACGCCCAAGCTTGATTGAAGGCCTGATTCGGGCGGGCATTCATCTTACCAACATTCGCACCG
CCCGCGATTTGCCGATGGGCTTGGCGATGTTGGGCATTCGCTAA

Upstream 100 bases:

>100_bases
CGGTGCTTAGCCCAATTTTGAGCCAGCATAATGTGCTGATTGTGCGTGATGTGCAGCAAAGTTTGCGCTATCTCAAGCGC
CAAATTTGAGCGAGGTGAGT

Downstream 100 bases:

>100_bases
ATGCCTAAGCGGTTGTAGAGATAGCTCATCCCTACGCCAAGAATCAGCGTGCCAAGGCCAGTCCACGTTGCGCCGGAGAT
CAGCGGCCAGTGCCAAGCAT

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRB [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MTAYESSRHHQPVEQTILAIHELIRAILLPRDLADVCRTIFEQLHHVLRFDAGFIEQYQPKTDTMQTIYSIDEGIENVVP
YAWDYRRSKVVTWIIANQQLVRFDDLHEDLPKRFTVENTRSFGQEEKRSRAWMSVPLLIGTDFVGVLNIQSYQPALYGEF
EEALLSTVASSVALALDNAQVLAELELEVSELDIPRIPLSDDVLIVPLIGVLDRLRWENLTHTILETLRERGCEHVLLDG
SGLLTFDPDAIQAISTIVKAIELIGAKSMLIGLRPSLIEGLIRAGIHLTNIRTARDLPMGLAMLGIR

Sequences:

>Translated_307_residues
MTAYESSRHHQPVEQTILAIHELIRAILLPRDLADVCRTIFEQLHHVLRFDAGFIEQYQPKTDTMQTIYSIDEGIENVVP
YAWDYRRSKVVTWIIANQQLVRFDDLHEDLPKRFTVENTRSFGQEEKRSRAWMSVPLLIGTDFVGVLNIQSYQPALYGEF
EEALLSTVASSVALALDNAQVLAELELEVSELDIPRIPLSDDVLIVPLIGVLDRLRWENLTHTILETLRERGCEHVLLDG
SGLLTFDPDAIQAISTIVKAIELIGAKSMLIGLRPSLIEGLIRAGIHLTNIRTARDLPMGLAMLGIR
>Mature_306_residues
TAYESSRHHQPVEQTILAIHELIRAILLPRDLADVCRTIFEQLHHVLRFDAGFIEQYQPKTDTMQTIYSIDEGIENVVPY
AWDYRRSKVVTWIIANQQLVRFDDLHEDLPKRFTVENTRSFGQEEKRSRAWMSVPLLIGTDFVGVLNIQSYQPALYGEFE
EALLSTVASSVALALDNAQVLAELELEVSELDIPRIPLSDDVLIVPLIGVLDRLRWENLTHTILETLRERGCEHVLLDGS
GLLTFDPDAIQAISTIVKAIELIGAKSMLIGLRPSLIEGLIRAGIHLTNIRTARDLPMGLAMLGIR

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 34682; Mature: 34550

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAYESSRHHQPVEQTILAIHELIRAILLPRDLADVCRTIFEQLHHVLRFDAGFIEQYQP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
KTDTMQTIYSIDEGIENVVPYAWDYRRSKVVTWIIANQQLVRFDDLHEDLPKRFTVENTR
CHHHHHHHHHHHHHHHHHCCCHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEECHHHH
SFGQEEKRSRAWMSVPLLIGTDFVGVLNIQSYQPALYGEFEEALLSTVASSVALALDNAQ
HCCHHHHHHHHHHCCHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
VLAELELEVSELDIPRIPLSDDVLIVPLIGVLDRLRWENLTHTILETLRERGCEHVLLDG
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
SGLLTFDPDAIQAISTIVKAIELIGAKSMLIGLRPSLIEGLIRAGIHLTNIRTARDLPMG
CEEEEECHHHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHCCEEEECCCHHHCCCHH
LAMLGIR
HHHHCCC
>Mature Secondary Structure 
TAYESSRHHQPVEQTILAIHELIRAILLPRDLADVCRTIFEQLHHVLRFDAGFIEQYQP
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
KTDTMQTIYSIDEGIENVVPYAWDYRRSKVVTWIIANQQLVRFDDLHEDLPKRFTVENTR
CHHHHHHHHHHHHHHHHHCCCHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEECHHHH
SFGQEEKRSRAWMSVPLLIGTDFVGVLNIQSYQPALYGEFEEALLSTVASSVALALDNAQ
HCCHHHHHHHHHHCCHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
VLAELELEVSELDIPRIPLSDDVLIVPLIGVLDRLRWENLTHTILETLRERGCEHVLLDG
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
SGLLTFDPDAIQAISTIVKAIELIGAKSMLIGLRPSLIEGLIRAGIHLTNIRTARDLPMG
CEEEEECHHHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHCCEEEECCCHHHCCCHH
LAMLGIR
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11157946 [H]