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The map label for this gene is erpA [H]

Identifier: 159899213

GI number: 159899213

Start: 3450996

End: 3451439

Strand: Direct

Name: erpA [H]

Synonym: Haur_2694

Alternate gene names: 159899213

Gene position: 3450996-3451439 (Clockwise)

Preceding gene: 159899212

Following gene: 159899214

Centisome position: 54.38

GC content: 51.13

Gene sequence:

>444_bases
ATGAGCGATGTAGCAGTAAAACCAATGACTGCCATTGAAATCGATCCAGCATTGGTCACGGTGACGGCATCAGCAGCAAA
TCGCTTGTTGTCGATCAAGCAAGAAAAAGAATTGTCCGATGAATATGCCCTGCGGGTTTTTGTAGCCGGCGGTGGCTGTT
CAGGTTTGCAATATGGTATGAGCTTCGATGATCAAACCAACGAAGGTGATACCGAATTCTTCGCCAGTGGCTTGCGGGTA
ATTGTAGACCCAATGAGCGCTCAATACATTGGCGGTGCCTCGATCGATTACATCGACAGTTTGATGGGTGGCGGTTTCAA
AATTGATAACCCCAACGCAACCTCAAGCTGTGGCTGTGGTAGCTCGTTCAAACCCAAAAACGGCGAAGCTTCCGCCAGTG
GTGGTAGCTGTGGCAGCGGGGCGGGCGGCTGCGGCTGTCACTAA

Upstream 100 bases:

>100_bases
TTTGCTTGCGTTTCAAGCTTTTTTCAAGTATGCTACAGGGAAGCAAATGCCATTTGAAGGCATGTTGTCAACCTGATTTT
CCGGCACAGGAGGCTCTCAA

Downstream 100 bases:

>100_bases
GCCTAGGCCCAAGCCTTAAGCTGTTTGACGATACAGTGAGCGGGGACGAGCAACTCGTCCCCGTTTGTTATGTTTCATGA
AGCGCAGACATTTCTATGGT

Product: iron-sulfur cluster assembly accessory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MSDVAVKPMTAIEIDPALVTVTASAANRLLSIKQEKELSDEYALRVFVAGGGCSGLQYGMSFDDQTNEGDTEFFASGLRV
IVDPMSAQYIGGASIDYIDSLMGGGFKIDNPNATSSCGCGSSFKPKNGEASASGGSCGSGAGGCGCH

Sequences:

>Translated_147_residues
MSDVAVKPMTAIEIDPALVTVTASAANRLLSIKQEKELSDEYALRVFVAGGGCSGLQYGMSFDDQTNEGDTEFFASGLRV
IVDPMSAQYIGGASIDYIDSLMGGGFKIDNPNATSSCGCGSSFKPKNGEASASGGSCGSGAGGCGCH
>Mature_146_residues
SDVAVKPMTAIEIDPALVTVTASAANRLLSIKQEKELSDEYALRVFVAGGGCSGLQYGMSFDDQTNEGDTEFFASGLRVI
VDPMSAQYIGGASIDYIDSLMGGGFKIDNPNATSSCGCGSSFKPKNGEASASGGSCGSGAGGCGCH

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=109, Percent_Identity=40.3669724770642, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI52426768, Length=121, Percent_Identity=28.099173553719, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1786351, Length=110, Percent_Identity=50, Blast_Score=109, Evalue=6e-26,
Organism=Escherichia coli, GI1788877, Length=105, Percent_Identity=35.2380952380952, Blast_Score=73, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71998452, Length=112, Percent_Identity=40.1785714285714, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25146411, Length=119, Percent_Identity=27.7310924369748, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193209025, Length=107, Percent_Identity=29.9065420560748, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325324, Length=146, Percent_Identity=31.5068493150685, Blast_Score=65, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323001, Length=107, Percent_Identity=29.9065420560748, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24649697, Length=114, Percent_Identity=42.1052631578947, Blast_Score=83, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24642263, Length=119, Percent_Identity=33.6134453781513, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 14926; Mature: 14795

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVAVKPMTAIEIDPALVTVTASAANRLLSIKQEKELSDEYALRVFVAGGGCSGLQYGM
CCCCCCCCEEEEEECCEEEEEEHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCC
SFDDQTNEGDTEFFASGLRVIVDPMSAQYIGGASIDYIDSLMGGGFKIDNPNATSSCGCG
CCCCCCCCCCHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCCCCCCC
SSFKPKNGEASASGGSCGSGAGGCGCH
CCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDVAVKPMTAIEIDPALVTVTASAANRLLSIKQEKELSDEYALRVFVAGGGCSGLQYGM
CCCCCCCEEEEEECCEEEEEEHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCC
SFDDQTNEGDTEFFASGLRVIVDPMSAQYIGGASIDYIDSLMGGGFKIDNPNATSSCGCG
CCCCCCCCCCHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCCCCCCC
SSFKPKNGEASASGGSCGSGAGGCGCH
CCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA