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The map label for this gene is tdk [H]

Identifier: 159899186

GI number: 159899186

Start: 3422216

End: 3422824

Strand: Reverse

Name: tdk [H]

Synonym: Haur_2667

Alternate gene names: 159899186

Gene position: 3422824-3422216 (Counterclockwise)

Preceding gene: 159899187

Following gene: 159899185

Centisome position: 53.93

GC content: 50.57

Gene sequence:

>609_bases
ATGCAACGTGGTGGGATTGAAGTTGTTTGCGGCAGTATGTTTAGCGGTAAAACCGAGGAATTGATTCGCCGCGTCAAGCG
TGCCCAAATTGCACGGCAAAAAATTCAGGTGTTTAAGCCAGCGATCGATACCCGCTATTCTGATGAAGAAGTAGCTTCAC
ATAATGGCGTGCGCGTGTTGGCAACGCCAGTGCAAACTGCTGCCGATATTGCCGCAGCAATTGCGCTTGAAACAACCGTT
GTGGCAATTGACGAAGTGCAGTTTTTTGACCCAGCTGTGATCGATTTATGTGATTTGTTAGCGCATCGCGGCGTGCGCGT
GATTGTCGCTGGCCTTGATCAAGATTTTCGTGGTGAGCCATTTGGCCCATTGCCAATCTTGCTCGCCAAAGCCGAAGAAG
TGACCAAACTACAAGCGATTTGTGTGATTTGCGGTCAGGCGGCTTCGCGCACCCAACGCTTGATCAACGGTATGCCAGCC
TCGTATGATGACCCAATTATTTTGGTTGGGGCGCAAGAAGCCTACGAAGCTCGTTGCCGCCGTTGCCATGAAGTGCCACG
TACCTATCGCAATGGCAATCATGCCAAAGAAACCGCAGTCAATAGCTAA

Upstream 100 bases:

>100_bases
TTCTGATATTTCGAAAGAGCCACGCGATTCCTTGTGGTGTCGCGTGGCTCTTTTGTTGCCTCGCGACCCTCGTTCCTCTA
AAATGCTATAAGGAGTTGTC

Downstream 100 bases:

>100_bases
CGATGGTGGGCTTGCAGCAACAATCAACTTCATCGCAGCCAAGCGCCGATTTTGCGCTCGCATTGTGCTCATTTGTTGGT
TACTTTGCTGCAAGCCATGT

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MQRGGIEVVCGSMFSGKTEELIRRVKRAQIARQKIQVFKPAIDTRYSDEEVASHNGVRVLATPVQTAADIAAAIALETTV
VAIDEVQFFDPAVIDLCDLLAHRGVRVIVAGLDQDFRGEPFGPLPILLAKAEEVTKLQAICVICGQAASRTQRLINGMPA
SYDDPIILVGAQEAYEARCRRCHEVPRTYRNGNHAKETAVNS

Sequences:

>Translated_202_residues
MQRGGIEVVCGSMFSGKTEELIRRVKRAQIARQKIQVFKPAIDTRYSDEEVASHNGVRVLATPVQTAADIAAAIALETTV
VAIDEVQFFDPAVIDLCDLLAHRGVRVIVAGLDQDFRGEPFGPLPILLAKAEEVTKLQAICVICGQAASRTQRLINGMPA
SYDDPIILVGAQEAYEARCRRCHEVPRTYRNGNHAKETAVNS
>Mature_202_residues
MQRGGIEVVCGSMFSGKTEELIRRVKRAQIARQKIQVFKPAIDTRYSDEEVASHNGVRVLATPVQTAADIAAAIALETTV
VAIDEVQFFDPAVIDLCDLLAHRGVRVIVAGLDQDFRGEPFGPLPILLAKAEEVTKLQAICVICGQAASRTQRLINGMPA
SYDDPIILVGAQEAYEARCRRCHEVPRTYRNGNHAKETAVNS

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Homo sapiens, GI164698438, Length=181, Percent_Identity=40.8839779005525, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17543396, Length=183, Percent_Identity=36.0655737704918, Blast_Score=103, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 22070; Mature: 22070

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRGGIEVVCGSMFSGKTEELIRRVKRAQIARQKIQVFKPAIDTRYSDEEVASHNGVRVL
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEE
ATPVQTAADIAAAIALETTVVAIDEVQFFDPAVIDLCDLLAHRGVRVIVAGLDQDFRGEP
ECCHHHHHHHHHHHHHHHHHEEEHHHHHCCHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
FGPLPILLAKAEEVTKLQAICVICGQAASRTQRLINGMPASYDDPIILVGAQEAYEARCR
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHH
RCHEVPRTYRNGNHAKETAVNS
HHHHHHHHHCCCCCHHHHCCCC
>Mature Secondary Structure
MQRGGIEVVCGSMFSGKTEELIRRVKRAQIARQKIQVFKPAIDTRYSDEEVASHNGVRVL
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEE
ATPVQTAADIAAAIALETTVVAIDEVQFFDPAVIDLCDLLAHRGVRVIVAGLDQDFRGEP
ECCHHHHHHHHHHHHHHHHHEEEHHHHHCCHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
FGPLPILLAKAEEVTKLQAICVICGQAASRTQRLINGMPASYDDPIILVGAQEAYEARCR
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHH
RCHEVPRTYRNGNHAKETAVNS
HHHHHHHHHCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA