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The map label for this gene is wecB [H]

Identifier: 159899122

GI number: 159899122

Start: 3343584

End: 3344642

Strand: Reverse

Name: wecB [H]

Synonym: Haur_2603

Alternate gene names: 159899122

Gene position: 3344642-3343584 (Counterclockwise)

Preceding gene: 159899123

Following gene: 159899121

Centisome position: 52.7

GC content: 50.61

Gene sequence:

>1059_bases
ATGAACATTGGGATTGTGCTTGGCACGCGGCCTGAGGTGATGAAAAATTATGCGATTGTGCAGGCATTACGCGCGGCTGA
TTTGCCGTTTGTGGTGCTTCACACCAATCAGCATCATGATCATTTGCTGCAAACCGCGATTTTTGGCCAAATGGGCTACA
TGCCCGACGAAGTTTTCCCGGGCAACTACAGCATCGGCGCAGCGATTGATTGGGTGCGCGAGCAAATTCGCCGCCATGAC
ATCGATTTGATTTTGGTCAATGGCGATACTGCGGCGGCCTTGGTTGGGGCAATTGCGGCAGTCTACTCCGATGTTGGGTT
GGCCCATGTTGAAGCAGGTCTACGAGCTTTCGATAAACGCATGTATGAAGAGCGCAATCGGATTATGGTCGATGGCGCAG
CCCATTATTTGTTCTCATACACCCAATATCAAGCCGATTATTTGGCCAAAATTCCCGATTTGCGTGGGCGAATTTTCAAT
ATTGGCAATACCACGGTTGACTTGATTCATGATTTTGCCCATGAACTCACGCCACGCCGCAACGATACTTATGCCTACAT
CACCTTGCATCGCAAGGAATTTACCGATAGCCGCGAATTGATGCAACAGGTTTTCAGCACAATCAATGAGCTGGCCCAAG
AATTCGATGCCATGATTTTTCCGATGCATCCGCGCACGCGGGCGGCCATGGAGCACTATGGTTTGAGCATGGATCTGCTC
AGTCGGGTGCAGGTACTTGATCCAGTTGAGCCATTTGAATCGCTGGCCTATGAAAAATACGCCAACATTATCATCACTGA
TAGTGGTTGTATTCAAGAAGAAGCTTATATTTTTGGCGTGCCCTGTGTGACGGTACGCGAGAATACCGAGCGGCCTGAAA
CGATCGATTCGGGCGCGAATGTGGTCACGGGCTTCGAGCCAACCGCAATTATCGCGGCGGTGCGCAATCAGCGAGCCAAA
AAAGGCCAGCAATTCTCCCCAGTTTACGGCGAACGTGGGGTTGGCCAACGGATCGTAGCAACCTTGCAAGCGCATTTTCG
CAGTTGGTCGGATTACTAA

Upstream 100 bases:

>100_bases
TGGTTGGTTTAAATCGCGATTGTTACGTTGACCCAGTGCACTTCAACGAAGATGGCAATCGGCGCGTCGCCGAATCATTC
TGTGAGGTCATTGTAAATTT

Downstream 100 bases:

>100_bases
ATTTGACGCAGCGCATTACAAAATAGCTTGCTAGAATCGGCTAAAAACGCATCCCTTGTGGATGCGTTTTCGTTTATAAT
TGGAGCGAATTGAATTAGTC

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MNIGIVLGTRPEVMKNYAIVQALRAADLPFVVLHTNQHHDHLLQTAIFGQMGYMPDEVFPGNYSIGAAIDWVREQIRRHD
IDLILVNGDTAAALVGAIAAVYSDVGLAHVEAGLRAFDKRMYEERNRIMVDGAAHYLFSYTQYQADYLAKIPDLRGRIFN
IGNTTVDLIHDFAHELTPRRNDTYAYITLHRKEFTDSRELMQQVFSTINELAQEFDAMIFPMHPRTRAAMEHYGLSMDLL
SRVQVLDPVEPFESLAYEKYANIIITDSGCIQEEAYIFGVPCVTVRENTERPETIDSGANVVTGFEPTAIIAAVRNQRAK
KGQQFSPVYGERGVGQRIVATLQAHFRSWSDY

Sequences:

>Translated_352_residues
MNIGIVLGTRPEVMKNYAIVQALRAADLPFVVLHTNQHHDHLLQTAIFGQMGYMPDEVFPGNYSIGAAIDWVREQIRRHD
IDLILVNGDTAAALVGAIAAVYSDVGLAHVEAGLRAFDKRMYEERNRIMVDGAAHYLFSYTQYQADYLAKIPDLRGRIFN
IGNTTVDLIHDFAHELTPRRNDTYAYITLHRKEFTDSRELMQQVFSTINELAQEFDAMIFPMHPRTRAAMEHYGLSMDLL
SRVQVLDPVEPFESLAYEKYANIIITDSGCIQEEAYIFGVPCVTVRENTERPETIDSGANVVTGFEPTAIIAAVRNQRAK
KGQQFSPVYGERGVGQRIVATLQAHFRSWSDY
>Mature_352_residues
MNIGIVLGTRPEVMKNYAIVQALRAADLPFVVLHTNQHHDHLLQTAIFGQMGYMPDEVFPGNYSIGAAIDWVREQIRRHD
IDLILVNGDTAAALVGAIAAVYSDVGLAHVEAGLRAFDKRMYEERNRIMVDGAAHYLFSYTQYQADYLAKIPDLRGRIFN
IGNTTVDLIHDFAHELTPRRNDTYAYITLHRKEFTDSRELMQQVFSTINELAQEFDAMIFPMHPRTRAAMEHYGLSMDLL
SRVQVLDPVEPFESLAYEKYANIIITDSGCIQEEAYIFGVPCVTVRENTERPETIDSGANVVTGFEPTAIIAAVRNQRAK
KGQQFSPVYGERGVGQRIVATLQAHFRSWSDY

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=379, Percent_Identity=28.7598944591029, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 39791; Mature: 39791

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGIVLGTRPEVMKNYAIVQALRAADLPFVVLHTNQHHDHLLQTAIFGQMGYMPDEVFP
CCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCC
GNYSIGAAIDWVREQIRRHDIDLILVNGDTAAALVGAIAAVYSDVGLAHVEAGLRAFDKR
CCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
MYEERNRIMVDGAAHYLFSYTQYQADYLAKIPDLRGRIFNIGNTTVDLIHDFAHELTPRR
HHHHCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCC
NDTYAYITLHRKEFTDSRELMQQVFSTINELAQEFDAMIFPMHPRTRAAMEHYGLSMDLL
CCCEEEEEEECHHCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHCCCHHHH
SRVQVLDPVEPFESLAYEKYANIIITDSGCIQEEAYIFGVPCVTVRENTERPETIDSGAN
HHHHHCCCCCHHHHHHHHHHCCEEEECCCCCCCCCEEEECCEEEECCCCCCCCCCCCCCC
VVTGFEPTAIIAAVRNQRAKKGQQFSPVYGERGVGQRIVATLQAHFRSWSDY
EEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNIGIVLGTRPEVMKNYAIVQALRAADLPFVVLHTNQHHDHLLQTAIFGQMGYMPDEVFP
CCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCC
GNYSIGAAIDWVREQIRRHDIDLILVNGDTAAALVGAIAAVYSDVGLAHVEAGLRAFDKR
CCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
MYEERNRIMVDGAAHYLFSYTQYQADYLAKIPDLRGRIFNIGNTTVDLIHDFAHELTPRR
HHHHCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCC
NDTYAYITLHRKEFTDSRELMQQVFSTINELAQEFDAMIFPMHPRTRAAMEHYGLSMDLL
CCCEEEEEEECHHCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHCCCHHHH
SRVQVLDPVEPFESLAYEKYANIIITDSGCIQEEAYIFGVPCVTVRENTERPETIDSGAN
HHHHHCCCCCHHHHHHHHHHCCEEEECCCCCCCCCEEEECCEEEECCCCCCCCCCCCCCC
VVTGFEPTAIIAAVRNQRAKKGQQFSPVYGERGVGQRIVATLQAHFRSWSDY
EEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA