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The map label for this gene is ureC

Identifier: 159898971

GI number: 159898971

Start: 3135302

End: 3137011

Strand: Reverse

Name: ureC

Synonym: Haur_2452

Alternate gene names: 159898971

Gene position: 3137011-3135302 (Counterclockwise)

Preceding gene: 159898972

Following gene: 159898970

Centisome position: 49.43

GC content: 51.99

Gene sequence:

>1710_bases
ATGAGCTTATGGATTCCGCGCCAAACCTATGCCGATTTGTATGGCCCGACCAAAGGCGACCGCTTGCGTTTAGCCGATAC
TGAATTAATTATCGAAATTGAACACGATTTTGCCCACTATGGCGATGAAATTACCTTCGGCGGCGGCAAGGTGATTCGCG
ATGGCATGGGCCAAAGCAGCAGCGCCCACGATGTGCTCGATTTAGTCATTACCAACGCGATCATTATCGATCATTGGGGC
ATCGTCAAAGGTGATATTGGGATCAAACAAGGCCGAATTGTTAAAGTTGGCAAGGCTGGCAATCCTGATACCATGGCCGG
AGTTGACCCTGAATTGGTGGTTGGCGCGAATACCGAGGTGATCGCTGGCGAGCATATGATCGTCACCGCTGGCGGGATTG
ATAGCCATATTCACTTTATTGCGCCTGGCCAAATTCCCGAAGCGCTTTCGAATGGCGTGACAACCCTACTTGGCGGCGGA
ACTGGCCCAGCTACTGGCACCAAAGCCACCACCTGTACGCCAGGTGTTTGGAATATGGCGCGAATGCTGCAAGCCGCCGA
TGCTTGGCCAGTTAATCTTGGCTTTTTGGGCAAAGGCAATGCTGCTCAGCCCGAATCGTTGATTCAGCAGATTCAGGCTG
GCGCATGTGGCTTGAAATTGCACGAGGATTGGGGCACAACGCCCGCTGCGATCGACATGTGTTTGAGCGTGGCCGATCAA
TACGATGTGCAAGTGGCAATTCACACCGACACAATCAACGAAGCTGGCTTTTTAGAAGATACAATTCGCGCGATTGCTGG
CCGCACTATCCATACCTATCACACTGAGGGTGCGGGCGGCGGCCATGCTCCCGATATTATCAAAATTGCTGGCGAACGCT
ATGTGCTACCCTCATCGACCAACCCCACCCGCCCATATACCGTCAACACGATCGCTGAACACCTTGATATGTTGATGGTT
TGTCATCACCTTAATCCCCAAGTGCCTGAAGATGTGGCCTTTGCTGAAAGCCGGATTCGACCTGAAACCATCGCCGCCGA
AGATATTTTGCATGATCTGGGAGTGATTAGCATGATCTCCAGCGATTCGCAGGCGATGGGTCGGGTTGGCGAAGTGGTGA
CCCGCACATGGCAAACTGCCCACAAAATGAAGGTTCAGCGTGGTGCGTTGCTTGGCGATTCAGCTCGCAACGATAATCAA
CGGGTCAAGCGTTATATTGCCAAATACACGATCAATCCAGCCTTAGCTCATGGCATTGCCCACGAAGTTGGCTCGATTGA
GCCAGGTAAATTGGCTGATTTGGTGTTGTGGCAGCCGGCCTTTTTTGGCGTAAAACCTGAAATTATTGTCAAAGGTGGCT
TGATTGCTTGGAATGCCATGGGCGATGCTAATGCTTCGATTCCCACGCCGCAGCCTGTGCTCTATCGCCCGATGTTTGGG
GCTTTTGGCGGGGCGCTTGGTGCAACGAGTTTGACCTTTGTTTCAGCCGCCGCTCATGAATCAGGCATTGGTCAACAATT
GAATTTACAAAAAGTGACTTCGGCGGTGCGCGGTTGCCGCAGCGTCCAAAAAGCCGATTTAATCCACAACAACGCTACTC
CGCTGATCGAAGTTGATCCCGAAACTTATGCGGTACGTGCTGATGGTGAGCTATTGACCTGCGAGCCAGCTACGAGTTTG
CCCTTGGCGCAGCGCTATTTCTTATTCTAA

Upstream 100 bases:

>100_bases
GCTTGGTTAATGGAGCGTTGGATGCCGTCGATCAGCGGCAAACTAGCCTCAACGCCGTTCAACAACAGCAATTTGGCCAT
CGGGCCCAAGGAGATTTGGA

Downstream 100 bases:

>100_bases
AATGAGGAAATTATGACCGAACAATTATTACGAATTGGGATTGCTGGACCTGTGGGCAGTGGCAAAACTGCCTTAGCCCA
CTGCTTGACCAGCCATCTGA

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MSLWIPRQTYADLYGPTKGDRLRLADTELIIEIEHDFAHYGDEITFGGGKVIRDGMGQSSSAHDVLDLVITNAIIIDHWG
IVKGDIGIKQGRIVKVGKAGNPDTMAGVDPELVVGANTEVIAGEHMIVTAGGIDSHIHFIAPGQIPEALSNGVTTLLGGG
TGPATGTKATTCTPGVWNMARMLQAADAWPVNLGFLGKGNAAQPESLIQQIQAGACGLKLHEDWGTTPAAIDMCLSVADQ
YDVQVAIHTDTINEAGFLEDTIRAIAGRTIHTYHTEGAGGGHAPDIIKIAGERYVLPSSTNPTRPYTVNTIAEHLDMLMV
CHHLNPQVPEDVAFAESRIRPETIAAEDILHDLGVISMISSDSQAMGRVGEVVTRTWQTAHKMKVQRGALLGDSARNDNQ
RVKRYIAKYTINPALAHGIAHEVGSIEPGKLADLVLWQPAFFGVKPEIIVKGGLIAWNAMGDANASIPTPQPVLYRPMFG
AFGGALGATSLTFVSAAAHESGIGQQLNLQKVTSAVRGCRSVQKADLIHNNATPLIEVDPETYAVRADGELLTCEPATSL
PLAQRYFLF

Sequences:

>Translated_569_residues
MSLWIPRQTYADLYGPTKGDRLRLADTELIIEIEHDFAHYGDEITFGGGKVIRDGMGQSSSAHDVLDLVITNAIIIDHWG
IVKGDIGIKQGRIVKVGKAGNPDTMAGVDPELVVGANTEVIAGEHMIVTAGGIDSHIHFIAPGQIPEALSNGVTTLLGGG
TGPATGTKATTCTPGVWNMARMLQAADAWPVNLGFLGKGNAAQPESLIQQIQAGACGLKLHEDWGTTPAAIDMCLSVADQ
YDVQVAIHTDTINEAGFLEDTIRAIAGRTIHTYHTEGAGGGHAPDIIKIAGERYVLPSSTNPTRPYTVNTIAEHLDMLMV
CHHLNPQVPEDVAFAESRIRPETIAAEDILHDLGVISMISSDSQAMGRVGEVVTRTWQTAHKMKVQRGALLGDSARNDNQ
RVKRYIAKYTINPALAHGIAHEVGSIEPGKLADLVLWQPAFFGVKPEIIVKGGLIAWNAMGDANASIPTPQPVLYRPMFG
AFGGALGATSLTFVSAAAHESGIGQQLNLQKVTSAVRGCRSVQKADLIHNNATPLIEVDPETYAVRADGELLTCEPATSL
PLAQRYFLF
>Mature_568_residues
SLWIPRQTYADLYGPTKGDRLRLADTELIIEIEHDFAHYGDEITFGGGKVIRDGMGQSSSAHDVLDLVITNAIIIDHWGI
VKGDIGIKQGRIVKVGKAGNPDTMAGVDPELVVGANTEVIAGEHMIVTAGGIDSHIHFIAPGQIPEALSNGVTTLLGGGT
GPATGTKATTCTPGVWNMARMLQAADAWPVNLGFLGKGNAAQPESLIQQIQAGACGLKLHEDWGTTPAAIDMCLSVADQY
DVQVAIHTDTINEAGFLEDTIRAIAGRTIHTYHTEGAGGGHAPDIIKIAGERYVLPSSTNPTRPYTVNTIAEHLDMLMVC
HHLNPQVPEDVAFAESRIRPETIAAEDILHDLGVISMISSDSQAMGRVGEVVTRTWQTAHKMKVQRGALLGDSARNDNQR
VKRYIAKYTINPALAHGIAHEVGSIEPGKLADLVLWQPAFFGVKPEIIVKGGLIAWNAMGDANASIPTPQPVLYRPMFGA
FGGALGATSLTFVSAAAHESGIGQQLNLQKVTSAVRGCRSVQKADLIHNNATPLIEVDPETYAVRADGELLTCEPATSLP
LAQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URE1_HERA2 (A9AZE6)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001545218.1
- ProteinModelPortal:   A9AZE6
- SMR:   A9AZE6
- GeneID:   5734332
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_2452
- HOGENOM:   HBG357507
- OMA:   MPYTINT
- ProtClustDB:   PRK13207
- BioCyc:   HAUR316274:HAUR_2452-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01953
- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950
- PRINTS:   PR01752
- TIGRFAMs:   TIGR01792

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha; SSF51338 Metalo_hydrolase

EC number: =3.5.1.5

Molecular weight: Translated: 60669; Mature: 60538

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS01120 UREASE_1; PS00145 UREASE_2; PS51368 UREASE_3

Important sites: ACT_SITE 322-322 BINDING 221-221

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLWIPRQTYADLYGPTKGDRLRLADTELIIEIEHDFAHYGDEITFGGGKVIRDGMGQSS
CCCCCCCHHHHHHCCCCCCCEEEEECCEEEEEEECHHHHCCCEEEECCCHHHHCCCCCCC
SAHDVLDLVITNAIIIDHWGIVKGDIGIKQGRIVKVGKAGNPDTMAGVDPELVVGANTEV
CHHHHHHHHHHCEEEEECCCEEECCCCCCCCCEEEECCCCCCCCCCCCCCCEEECCCCEE
IAGEHMIVTAGGIDSHIHFIAPGQIPEALSNGVTTLLGGGTGPATGTKATTCTPGVWNMA
EECCEEEEEECCCCCCEEEEECCCCHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHH
RMLQAADAWPVNLGFLGKGNAAQPESLIQQIQAGACGLKLHEDWGTTPAAIDMCLSVADQ
HHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHCC
YDVQVAIHTDTINEAGFLEDTIRAIAGRTIHTYHTEGAGGGHAPDIIKIAGERYVLPSST
CEEEEEEEECCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEECCCEEECCCCC
NPTRPYTVNTIAEHLDMLMVCHHLNPQVPEDVAFAESRIRPETIAAEDILHDLGVISMIS
CCCCCEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
SDSQAMGRVGEVVTRTWQTAHKMKVQRGALLGDSARNDNQRVKRYIAKYTINPALAHGIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHCCCHHHHHHHH
HEVGSIEPGKLADLVLWQPAFFGVKPEIIVKGGLIAWNAMGDANASIPTPQPVLYRPMFG
HHHCCCCCCCHHEEEEECCHHCCCCCEEEEECCEEEEECCCCCCCCCCCCCCEEECCHHH
AFGGALGATSLTFVSAAAHESGIGQQLNLQKVTSAVRGCRSVQKADLIHNNATPLIEVDP
HHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
ETYAVRADGELLTCEPATSLPLAQRYFLF
CEEEEEECCCEEEECCCCCCCHHHHHHCC
>Mature Secondary Structure 
SLWIPRQTYADLYGPTKGDRLRLADTELIIEIEHDFAHYGDEITFGGGKVIRDGMGQSS
CCCCCCHHHHHHCCCCCCCEEEEECCEEEEEEECHHHHCCCEEEECCCHHHHCCCCCCC
SAHDVLDLVITNAIIIDHWGIVKGDIGIKQGRIVKVGKAGNPDTMAGVDPELVVGANTEV
CHHHHHHHHHHCEEEEECCCEEECCCCCCCCCEEEECCCCCCCCCCCCCCCEEECCCCEE
IAGEHMIVTAGGIDSHIHFIAPGQIPEALSNGVTTLLGGGTGPATGTKATTCTPGVWNMA
EECCEEEEEECCCCCCEEEEECCCCHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHH
RMLQAADAWPVNLGFLGKGNAAQPESLIQQIQAGACGLKLHEDWGTTPAAIDMCLSVADQ
HHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHCC
YDVQVAIHTDTINEAGFLEDTIRAIAGRTIHTYHTEGAGGGHAPDIIKIAGERYVLPSST
CEEEEEEEECCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEECCCEEECCCCC
NPTRPYTVNTIAEHLDMLMVCHHLNPQVPEDVAFAESRIRPETIAAEDILHDLGVISMIS
CCCCCEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
SDSQAMGRVGEVVTRTWQTAHKMKVQRGALLGDSARNDNQRVKRYIAKYTINPALAHGIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHCCCHHHHHHHH
HEVGSIEPGKLADLVLWQPAFFGVKPEIIVKGGLIAWNAMGDANASIPTPQPVLYRPMFG
HHHCCCCCCCHHEEEEECCHHCCCCCEEEEECCEEEEECCCCCCCCCCCCCCEEECCHHH
AFGGALGATSLTFVSAAAHESGIGQQLNLQKVTSAVRGCRSVQKADLIHNNATPLIEVDP
HHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
ETYAVRADGELLTCEPATSLPLAQRYFLF
CEEEEEECCCEEEECCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA