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The map label for this gene is eryA [H]

Identifier: 159898937

GI number: 159898937

Start: 3095212

End: 3099120

Strand: Direct

Name: eryA [H]

Synonym: Haur_2416

Alternate gene names: 159898937

Gene position: 3095212-3099120 (Clockwise)

Preceding gene: 159898936

Following gene: 159898938

Centisome position: 48.77

GC content: 53.08

Gene sequence:

>3909_bases
ATGAGTTATGATGAAACCGATGGCAATTTTGATATTGCTGTGGTAGGTTTGGCGGGGCGCTGGGCTGGCGCTCCCGATAT
TGATCACTTTTGGCAGCAGCTTTGTGCTGGAGCCGAGGGCATTAGCTTTTTTGATGACGAGCAATTGCTAGCCGCAGGCG
TAACGCCTGAGCAACTAGCCCATCCACGCTATGTCAAAGCTGGCTCGGTGCTCGAAGGGGTCGAGCTATTCGATGCAGCC
TTTTTTGGCTATTCGCCACGCGAGGCCGAATTGCTCGATCCGCAGCAGCGGATTTTTCTGGAATGTGCTTGGCAAGCCTT
GGAACATGCAGGCTACAACGCCTCAACCTATCCCGGCTTAATCGGCGTATTTGCTGGTTCAAGCCTCAATACCTACTTGC
TGCGTAACCTAGCCAGCCAACAAGGCCGAGGCACAATTCCCGATCTGTTTCAACTGATTATGGGCAACGACAAAGACTTT
TTGCCCACTCGAGTCAGCTATAAGTTGAATTTGCGCGGGCCAAGTTTTAGCGTGCAAAGTGCCTGCTCAACCTCATTGGT
CGCAACCCATTTGGCCTGCCAAAGCCTGTTGGGCTATCAATGCGATATCGCGCTGGCTGGCGGAATTTCGATCACCGTGC
CGCAACATCAAGGCTATCTGGCCCAAGAAGGCGGCATTCTCGCCCCAGACGGCCATTGCCGCACATTCGATGCCCAAGCC
CAAGGCACACTCAACGGCAACGGTGCAGGTATCGTGGTTTTGAAACGGCTCGACGATGCCTTGGCTGATGGCGATTCGAT
CTATGCGGTAATCAAAGGCTCAGCCGTCAACAACGATGGTGCGCTCAAAATTGGCTACACGGCACCGAGCATTGATGGGC
AGGCCGCTGTGATTCAGGCCGCTCAAGCGGTGGCTGATGTTGATCCAGTAACGATTTCCTATATCGAAGCCCATGGAACG
GCCACTGCCCTCGGCGATCCAATCGAAGTTGCCGCTTTAACCAAGGCCTTCCGTCAACAAACTGATAAAACGCAGTTTTG
TATGCTTGGCTCGGTCAAATCCAATTTTGGGCATCTTGATACTGCGGCGGGCGTAACCAGCTTGATTAAAACCGTGCTGG
CCCTGCATCACAATAGAATTCCCGCCAGCTTGCATTTTCAAACCCCCAATCCGCAACTTGAGCTAGAAAGCTCACCATTT
TATGTCAACACTAAATTAAGTGATTGGCCAAGCGATCAGCCAATTCGGCGGGCGGGGGTCAGTTCATTTGGGATTGGCGG
CACGAATGCGCATATTGTGCTCGAAGAAGCGCCCATGCTCGAACCAACCGAGGAAACTGACGCTTGGCACATGCTGGTGA
TTTCGGGGCGTAATCGGGCTACCTTGAATGCGGCCACCAAAAATCTGGCCGAGCACCTTGAGGCTAATCCCCAATTGGCC
TTGGCTGATGTTGCCTACACCTTACAAGTTGGCCGCCAAGCCTTTAATCATCGGCGGGTGTTGCTGTGCCGTTCGCTGGA
TGAAGCCAGCCAAATTTTGCGCCAACGCGATAAGCGCATGATCAGCGGCCAAGTCAGCGCGGCTACGCCTGCGGTGGTGT
TTATGTTTCCGGGCGGCGGCGTACAATATCCCAGCATGGGCCAAGAACTCTATCAAACTCAGCCGATCTTCCGTGCGGCG
GTTGAACGCTGTTTGGCCATGCTTAAACCTGAAATCAGCGCCAATCTACGCCAGTTGGTCTATAGCGAAAACGCCAAAGT
TCATGAGCAACAATTGGCGACAATGCTCTACAGTTTGTTGGCAATTTTCATCAGTGAGTATGCGCTTGCTCAATTATGGC
TGGCATGGGGCATTCAGCCTGTCGCCTTGATTGGCCATAGTTTGGGTGAATATACCGCGGCCCATTTGGCTGGCTCGATC
TCACTTGAGGCGGCTTTGCGCTTAGTTGAGCTACGTGGCCGCTTGATGGATCAGCTTGAAGATGGCGCGATGATCAACAT
TGCCCTTGCTGAAGCTGAGGTTTTGCCGTTGCTCGGCGAACAACTTTCGCTAGCGGCAGTCAATGGGCCTGAACATTCGG
TCGTGGCTGGCTCGATTGCAGCAATTCAAGCCCTTGAGTTTGAGCTAGAACAGCGGGCGATCAAATATCGACGCTTGCCA
ATTCGCGTGGCAGCCCATTCCAGTTTGCTCAAGCCAATTGTGGCCGAATTTGCGACATTTGCCCAGACGATCAGCATGCA
ACCAGCCACAATTCCCTATATTTCCAATGTAACTGGCGGTTGGATGAGCCATGAACAATGGTCAAACCCGAACTATTGGA
CTGAGCATTTACAATCGACCGTGCGATTTAGCGCTGGGATGAGCCAACTTTTGCAAAATCCAGCTCATCTATTTCTCGAA
GTTGGGCCTGGCCAAACGCTCACAACCTTAACTCGCGCTCAAGCCAACTTTGGAGCCGAACGGGTGGTAGCGCAGTCGAT
GCGCCATCCCCAAGATCAACAAACTGACACCCAATGTTTGTTGACTGCGGTCGGGCGGTTATGGCTGGCTGGCGTGGCGA
TCGATTGGGCCAAACTAAGCGCCAGCAAGCGTCGCCGCGTGGCCCTACCAACTTATCCCTTCGAACGCAAACGCTACTGG
GTTGAGCAATTTATCAATAATGAAACCCAAGGCCCGACCTTGCTCGAAGCGGCGCAAGGTGGTTATAGCTTGCCCGAAAG
CAGCGAGCCAGCCGAGGCCAGCCCTGGCTACGAACGGCCTAATCTCACGACTGAATATGTCGCGCCCAGCAATAACCTTG
AGCATATGATCACCGCGCTGTGGGGTGCTGTCTTGGGCGTACCGCTGATTGGTATTCACGACAATTTCTTTGAGTTGGGC
GGCGATTCGCTGCTAGCCTTACAAGTTGCGACCCATCTCACCGAAAAAGTGCATACCACAATCGGCGTGCGCAGTTTATT
CGAAGCCCCAACGATCGCCGAGCTGGCCCAGCTTGTGCAAGCCCAAACCGCCGAACAAGCAGGCGAATTATCGTCGTTGG
TACGCTTGCAACCACAAGGCCAAGCAGCGCCGTTCTTTTGTATTCACCCCATGAGCGGTATGGCCAATGTCTATGCAGCT
TTGGCCCAATTGCTTGGCACGCAACGCCCATTCTACGGGGTGCAGGCCTTTGGCTTGGAATACCCTGAAATGCCACTTGA
CGATATTACAGTTATGGCGCAACGCTATCTCAGCGATATCCGTCAGGTTCAGCCGCAAGGGCCATATCTGCTTGGCGGCT
GGTCGATGGGTGGCTCGATTGCCTTTGAAATTGCCAGCCAATTAGTGGCTCAAGGCGAAACGGTGAGCTTGCTGGCCTTG
ATCGACACGCCCGCCAAACTAACAGGCACATCACCAGCAACACTAACCGATTTGGAGCTGTTGATCGCCATGCTTGGGGT
CGATGCCAACATTTTAGGGATCGACGATCCCAAGGCTGAGGCCAGCGAAGCAGTTTGGAACGAATTACTGAGCATTATCA
AGCAACATCTTGGCTTGCCCGAAAGCTACACCTTACAGCGTTTGCGCCACCTGGTCAGCACCTTCCGCACCCACTCGCAA
GCAGTTTGGAATTATCAGCCAGCTAACTATCCCAACGATGTGCTAATTTTACGGGCCGCCGATTTGGCAGGCGAGCACGA
CGACCAACTGAACGAGGCATATCGCATAGCCGATTTAGGCTGGAGCCAGTTTGTCACAGGCCAAATTCAAGTCCAAACCA
TTCCAGGCACGCACAACACCCTGTTGAACGAACCGTCGTTGCCAATCTTGGCTAGTCATCTCGCGGTAGCGTTACACAAC
GTTGCCGCAAATACATCTTTGACACCATCACACCATGAAGGATCAAATGAAATTGCCATTATGGATTGA

Upstream 100 bases:

>100_bases
CTCAAGCGTCAACCTTTGTTGATCGCGACAATCGAGCGCAGCAACAGCGCCAAGCTATGCAACGTCAACGTCGCCGCCGC
TAGCAGAGAGGAATATATCG

Downstream 100 bases:

>100_bases
GTGGTTGCGCAAGCAACCTAACGCCGCCCTGCGGCTCTTTTGTTTTCATTATGCTGGGGGCACGGCACAACGTGCCCACC
AGTGGACACAACAACTCGCA

Product: beta-ketoacyl synthase

Products: NA

Alternate protein names: 6-deoxyerythronolide B synthase II; DEBS 2; ORF 2 [H]

Number of amino acids: Translated: 1302; Mature: 1301

Protein sequence:

>1302_residues
MSYDETDGNFDIAVVGLAGRWAGAPDIDHFWQQLCAGAEGISFFDDEQLLAAGVTPEQLAHPRYVKAGSVLEGVELFDAA
FFGYSPREAELLDPQQRIFLECAWQALEHAGYNASTYPGLIGVFAGSSLNTYLLRNLASQQGRGTIPDLFQLIMGNDKDF
LPTRVSYKLNLRGPSFSVQSACSTSLVATHLACQSLLGYQCDIALAGGISITVPQHQGYLAQEGGILAPDGHCRTFDAQA
QGTLNGNGAGIVVLKRLDDALADGDSIYAVIKGSAVNNDGALKIGYTAPSIDGQAAVIQAAQAVADVDPVTISYIEAHGT
ATALGDPIEVAALTKAFRQQTDKTQFCMLGSVKSNFGHLDTAAGVTSLIKTVLALHHNRIPASLHFQTPNPQLELESSPF
YVNTKLSDWPSDQPIRRAGVSSFGIGGTNAHIVLEEAPMLEPTEETDAWHMLVISGRNRATLNAATKNLAEHLEANPQLA
LADVAYTLQVGRQAFNHRRVLLCRSLDEASQILRQRDKRMISGQVSAATPAVVFMFPGGGVQYPSMGQELYQTQPIFRAA
VERCLAMLKPEISANLRQLVYSENAKVHEQQLATMLYSLLAIFISEYALAQLWLAWGIQPVALIGHSLGEYTAAHLAGSI
SLEAALRLVELRGRLMDQLEDGAMINIALAEAEVLPLLGEQLSLAAVNGPEHSVVAGSIAAIQALEFELEQRAIKYRRLP
IRVAAHSSLLKPIVAEFATFAQTISMQPATIPYISNVTGGWMSHEQWSNPNYWTEHLQSTVRFSAGMSQLLQNPAHLFLE
VGPGQTLTTLTRAQANFGAERVVAQSMRHPQDQQTDTQCLLTAVGRLWLAGVAIDWAKLSASKRRRVALPTYPFERKRYW
VEQFINNETQGPTLLEAAQGGYSLPESSEPAEASPGYERPNLTTEYVAPSNNLEHMITALWGAVLGVPLIGIHDNFFELG
GDSLLALQVATHLTEKVHTTIGVRSLFEAPTIAELAQLVQAQTAEQAGELSSLVRLQPQGQAAPFFCIHPMSGMANVYAA
LAQLLGTQRPFYGVQAFGLEYPEMPLDDITVMAQRYLSDIRQVQPQGPYLLGGWSMGGSIAFEIASQLVAQGETVSLLAL
IDTPAKLTGTSPATLTDLELLIAMLGVDANILGIDDPKAEASEAVWNELLSIIKQHLGLPESYTLQRLRHLVSTFRTHSQ
AVWNYQPANYPNDVLILRAADLAGEHDDQLNEAYRIADLGWSQFVTGQIQVQTIPGTHNTLLNEPSLPILASHLAVALHN
VAANTSLTPSHHEGSNEIAIMD

Sequences:

>Translated_1302_residues
MSYDETDGNFDIAVVGLAGRWAGAPDIDHFWQQLCAGAEGISFFDDEQLLAAGVTPEQLAHPRYVKAGSVLEGVELFDAA
FFGYSPREAELLDPQQRIFLECAWQALEHAGYNASTYPGLIGVFAGSSLNTYLLRNLASQQGRGTIPDLFQLIMGNDKDF
LPTRVSYKLNLRGPSFSVQSACSTSLVATHLACQSLLGYQCDIALAGGISITVPQHQGYLAQEGGILAPDGHCRTFDAQA
QGTLNGNGAGIVVLKRLDDALADGDSIYAVIKGSAVNNDGALKIGYTAPSIDGQAAVIQAAQAVADVDPVTISYIEAHGT
ATALGDPIEVAALTKAFRQQTDKTQFCMLGSVKSNFGHLDTAAGVTSLIKTVLALHHNRIPASLHFQTPNPQLELESSPF
YVNTKLSDWPSDQPIRRAGVSSFGIGGTNAHIVLEEAPMLEPTEETDAWHMLVISGRNRATLNAATKNLAEHLEANPQLA
LADVAYTLQVGRQAFNHRRVLLCRSLDEASQILRQRDKRMISGQVSAATPAVVFMFPGGGVQYPSMGQELYQTQPIFRAA
VERCLAMLKPEISANLRQLVYSENAKVHEQQLATMLYSLLAIFISEYALAQLWLAWGIQPVALIGHSLGEYTAAHLAGSI
SLEAALRLVELRGRLMDQLEDGAMINIALAEAEVLPLLGEQLSLAAVNGPEHSVVAGSIAAIQALEFELEQRAIKYRRLP
IRVAAHSSLLKPIVAEFATFAQTISMQPATIPYISNVTGGWMSHEQWSNPNYWTEHLQSTVRFSAGMSQLLQNPAHLFLE
VGPGQTLTTLTRAQANFGAERVVAQSMRHPQDQQTDTQCLLTAVGRLWLAGVAIDWAKLSASKRRRVALPTYPFERKRYW
VEQFINNETQGPTLLEAAQGGYSLPESSEPAEASPGYERPNLTTEYVAPSNNLEHMITALWGAVLGVPLIGIHDNFFELG
GDSLLALQVATHLTEKVHTTIGVRSLFEAPTIAELAQLVQAQTAEQAGELSSLVRLQPQGQAAPFFCIHPMSGMANVYAA
LAQLLGTQRPFYGVQAFGLEYPEMPLDDITVMAQRYLSDIRQVQPQGPYLLGGWSMGGSIAFEIASQLVAQGETVSLLAL
IDTPAKLTGTSPATLTDLELLIAMLGVDANILGIDDPKAEASEAVWNELLSIIKQHLGLPESYTLQRLRHLVSTFRTHSQ
AVWNYQPANYPNDVLILRAADLAGEHDDQLNEAYRIADLGWSQFVTGQIQVQTIPGTHNTLLNEPSLPILASHLAVALHN
VAANTSLTPSHHEGSNEIAIMD
>Mature_1301_residues
SYDETDGNFDIAVVGLAGRWAGAPDIDHFWQQLCAGAEGISFFDDEQLLAAGVTPEQLAHPRYVKAGSVLEGVELFDAAF
FGYSPREAELLDPQQRIFLECAWQALEHAGYNASTYPGLIGVFAGSSLNTYLLRNLASQQGRGTIPDLFQLIMGNDKDFL
PTRVSYKLNLRGPSFSVQSACSTSLVATHLACQSLLGYQCDIALAGGISITVPQHQGYLAQEGGILAPDGHCRTFDAQAQ
GTLNGNGAGIVVLKRLDDALADGDSIYAVIKGSAVNNDGALKIGYTAPSIDGQAAVIQAAQAVADVDPVTISYIEAHGTA
TALGDPIEVAALTKAFRQQTDKTQFCMLGSVKSNFGHLDTAAGVTSLIKTVLALHHNRIPASLHFQTPNPQLELESSPFY
VNTKLSDWPSDQPIRRAGVSSFGIGGTNAHIVLEEAPMLEPTEETDAWHMLVISGRNRATLNAATKNLAEHLEANPQLAL
ADVAYTLQVGRQAFNHRRVLLCRSLDEASQILRQRDKRMISGQVSAATPAVVFMFPGGGVQYPSMGQELYQTQPIFRAAV
ERCLAMLKPEISANLRQLVYSENAKVHEQQLATMLYSLLAIFISEYALAQLWLAWGIQPVALIGHSLGEYTAAHLAGSIS
LEAALRLVELRGRLMDQLEDGAMINIALAEAEVLPLLGEQLSLAAVNGPEHSVVAGSIAAIQALEFELEQRAIKYRRLPI
RVAAHSSLLKPIVAEFATFAQTISMQPATIPYISNVTGGWMSHEQWSNPNYWTEHLQSTVRFSAGMSQLLQNPAHLFLEV
GPGQTLTTLTRAQANFGAERVVAQSMRHPQDQQTDTQCLLTAVGRLWLAGVAIDWAKLSASKRRRVALPTYPFERKRYWV
EQFINNETQGPTLLEAAQGGYSLPESSEPAEASPGYERPNLTTEYVAPSNNLEHMITALWGAVLGVPLIGIHDNFFELGG
DSLLALQVATHLTEKVHTTIGVRSLFEAPTIAELAQLVQAQTAEQAGELSSLVRLQPQGQAAPFFCIHPMSGMANVYAAL
AQLLGTQRPFYGVQAFGLEYPEMPLDDITVMAQRYLSDIRQVQPQGPYLLGGWSMGGSIAFEIASQLVAQGETVSLLALI
DTPAKLTGTSPATLTDLELLIAMLGVDANILGIDDPKAEASEAVWNELLSIIKQHLGLPESYTLQRLRHLVSTFRTHSQA
VWNYQPANYPNDVLILRAADLAGEHDDQLNEAYRIADLGWSQFVTGQIQVQTIPGTHNTLLNEPSLPILASHLAVALHNV
AANTSLTPSHHEGSNEIAIMD

Specific function: Activates The Carboxylate Group Of L-Serine Via ATP- Dependent Ppi Exchange Reactions To The Aminoacyladenylate, Preparing That Molecule For The Final Stages Of Enterobactin Synthesis. Holo-Entf Acts As The Catalyst For The Formation Of The Three Amide An

COG id: COG3321

COG function: function code Q; Polyketide synthase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=866, Percent_Identity=26.7898383371824, Blast_Score=254, Evalue=3e-67,
Organism=Homo sapiens, GI8923559, Length=278, Percent_Identity=30.9352517985612, Blast_Score=110, Evalue=1e-23,
Organism=Homo sapiens, GI223972627, Length=178, Percent_Identity=34.2696629213483, Blast_Score=79, Evalue=3e-14,
Organism=Escherichia coli, GI1786801, Length=198, Percent_Identity=32.3232323232323, Blast_Score=103, Evalue=9e-23,
Organism=Escherichia coli, GI1788663, Length=274, Percent_Identity=31.3868613138686, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1787334, Length=299, Percent_Identity=30.4347826086957, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1787337, Length=271, Percent_Identity=26.9372693726937, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17550940, Length=878, Percent_Identity=27.3348519362187, Blast_Score=307, Evalue=3e-83,
Organism=Caenorhabditis elegans, GI212642053, Length=879, Percent_Identity=26.962457337884, Blast_Score=275, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI71983541, Length=300, Percent_Identity=29, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71983535, Length=269, Percent_Identity=28.996282527881, Blast_Score=90, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6320904, Length=321, Percent_Identity=29.9065420560748, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI221330659, Length=863, Percent_Identity=26.4194669756663, Blast_Score=262, Evalue=1e-69,
Organism=Drosophila melanogaster, GI19920632, Length=863, Percent_Identity=26.4194669756663, Blast_Score=261, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24581345, Length=889, Percent_Identity=26.4341957255343, Blast_Score=258, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24644341, Length=278, Percent_Identity=32.0143884892086, Blast_Score=110, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR002198
- InterPro:   IPR015357
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR020806
- InterPro:   IPR015083
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00106 adh_short; PF00107 ADH_zinc_N; PF08990 Docking; PF09277 Erythro-docking; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF00550 PP-binding [H]

EC number: =2.3.1.94 [H]

Molecular weight: Translated: 141019; Mature: 140887

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYDETDGNFDIAVVGLAGRWAGAPDIDHFWQQLCAGAEGISFFDDEQLLAAGVTPEQLA
CCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHCCCCCHHHHC
HPRYVKAGSVLEGVELFDAAFFGYSPREAELLDPQQRIFLECAWQALEHAGYNASTYPGL
CCCEECCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCE
IGVFAGSSLNTYLLRNLASQQGRGTIPDLFQLIMGNDKDFLPTRVSYKLNLRGPSFSVQS
EEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCHHH
ACSTSLVATHLACQSLLGYQCDIALAGGISITVPQHQGYLAQEGGILAPDGHCRTFDAQA
HHHHHHHHHHHHHHHHHCCEEEEEEECCEEEEECCCCCEEECCCCEECCCCCCEEECCCC
QGTLNGNGAGIVVLKRLDDALADGDSIYAVIKGSAVNNDGALKIGYTAPSIDGQAAVIQA
CCCCCCCCCEEEEEEEHHHHHCCCCEEEEEEECCEECCCCCEEEEEECCCCCCHHHHHHH
AQAVADVDPVTISYIEAHGTATALGDPIEVAALTKAFRQQTDKTQFCMLGSVKSNFGHLD
HHHHHCCCCCEEEEEEECCCHHCCCCCHHHHHHHHHHHHHCCCCCEEEEECHHCCCCCCH
TAAGVTSLIKTVLALHHNRIPASLHFQTPNPQLELESSPFYVNTKLSDWPSDQPIRRAGV
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEECCCCEEEEEECCCCCCCCCHHHHCC
SSFGIGGTNAHIVLEEAPMLEPTEETDAWHMLVISGRNRATLNAATKNLAEHLEANPQLA
CCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCEEHHHHHHHHHHHHCCCCCEE
LADVAYTLQVGRQAFNHRRVLLCRSLDEASQILRQRDKRMISGQVSAATPAVVFMFPGGG
HHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
VQYPSMGQELYQTQPIFRAAVERCLAMLKPEISANLRQLVYSENAKVHEQQLATMLYSLL
CCCCCHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AIFISEYALAQLWLAWGIQPVALIGHSLGEYTAAHLAGSISLEAALRLVELRGRLMDQLE
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
DGAMINIALAEAEVLPLLGEQLSLAAVNGPEHSVVAGSIAAIQALEFELEQRAIKYRRLP
CCCEEEEEECCHHHHHHHCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCC
IRVAAHSSLLKPIVAEFATFAQTISMQPATIPYISNVTGGWMSHEQWSNPNYWTEHLQST
EEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
VRFSAGMSQLLQNPAHLFLEVGPGQTLTTLTRAQANFGAERVVAQSMRHPQDQQTDTQCL
HHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHH
LTAVGRLWLAGVAIDWAKLSASKRRRVALPTYPFERKRYWVEQFINNETQGPTLLEAAQG
HHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCC
GYSLPESSEPAEASPGYERPNLTTEYVAPSNNLEHMITALWGAVLGVPLIGIHDNFFELG
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHC
GDSLLALQVATHLTEKVHTTIGVRSLFEAPTIAELAQLVQAQTAEQAGELSSLVRLQPQG
CCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCC
QAAPFFCIHPMSGMANVYAALAQLLGTQRPFYGVQAFGLEYPEMPLDDITVMAQRYLSDI
CCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHEECCCCCCCCHHHHHHHHHHHHHHH
RQVQPQGPYLLGGWSMGGSIAFEIASQLVAQGETVSLLALIDTPAKLTGTSPATLTDLEL
HHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHH
LIAMLGVDANILGIDDPKAEASEAVWNELLSIIKQHLGLPESYTLQRLRHLVSTFRTHSQ
HHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AVWNYQPANYPNDVLILRAADLAGEHDDQLNEAYRIADLGWSQFVTGQIQVQTIPGTHNT
HEECCCCCCCCCCEEEEEEHHHCCCCCHHHHHHHHHHHCCHHHEEECEEEEEECCCCCHH
LLNEPSLPILASHLAVALHNVAANTSLTPSHHEGSNEIAIMD
HCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEC
>Mature Secondary Structure 
SYDETDGNFDIAVVGLAGRWAGAPDIDHFWQQLCAGAEGISFFDDEQLLAAGVTPEQLA
CCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHCCCCCHHHHC
HPRYVKAGSVLEGVELFDAAFFGYSPREAELLDPQQRIFLECAWQALEHAGYNASTYPGL
CCCEECCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCE
IGVFAGSSLNTYLLRNLASQQGRGTIPDLFQLIMGNDKDFLPTRVSYKLNLRGPSFSVQS
EEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCHHH
ACSTSLVATHLACQSLLGYQCDIALAGGISITVPQHQGYLAQEGGILAPDGHCRTFDAQA
HHHHHHHHHHHHHHHHHCCEEEEEEECCEEEEECCCCCEEECCCCEECCCCCCEEECCCC
QGTLNGNGAGIVVLKRLDDALADGDSIYAVIKGSAVNNDGALKIGYTAPSIDGQAAVIQA
CCCCCCCCCEEEEEEEHHHHHCCCCEEEEEEECCEECCCCCEEEEEECCCCCCHHHHHHH
AQAVADVDPVTISYIEAHGTATALGDPIEVAALTKAFRQQTDKTQFCMLGSVKSNFGHLD
HHHHHCCCCCEEEEEEECCCHHCCCCCHHHHHHHHHHHHHCCCCCEEEEECHHCCCCCCH
TAAGVTSLIKTVLALHHNRIPASLHFQTPNPQLELESSPFYVNTKLSDWPSDQPIRRAGV
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEECCCCEEEEEECCCCCCCCCHHHHCC
SSFGIGGTNAHIVLEEAPMLEPTEETDAWHMLVISGRNRATLNAATKNLAEHLEANPQLA
CCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCEEHHHHHHHHHHHHCCCCCEE
LADVAYTLQVGRQAFNHRRVLLCRSLDEASQILRQRDKRMISGQVSAATPAVVFMFPGGG
HHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
VQYPSMGQELYQTQPIFRAAVERCLAMLKPEISANLRQLVYSENAKVHEQQLATMLYSLL
CCCCCHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AIFISEYALAQLWLAWGIQPVALIGHSLGEYTAAHLAGSISLEAALRLVELRGRLMDQLE
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
DGAMINIALAEAEVLPLLGEQLSLAAVNGPEHSVVAGSIAAIQALEFELEQRAIKYRRLP
CCCEEEEEECCHHHHHHHCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCC
IRVAAHSSLLKPIVAEFATFAQTISMQPATIPYISNVTGGWMSHEQWSNPNYWTEHLQST
EEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
VRFSAGMSQLLQNPAHLFLEVGPGQTLTTLTRAQANFGAERVVAQSMRHPQDQQTDTQCL
HHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHH
LTAVGRLWLAGVAIDWAKLSASKRRRVALPTYPFERKRYWVEQFINNETQGPTLLEAAQG
HHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCC
GYSLPESSEPAEASPGYERPNLTTEYVAPSNNLEHMITALWGAVLGVPLIGIHDNFFELG
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHC
GDSLLALQVATHLTEKVHTTIGVRSLFEAPTIAELAQLVQAQTAEQAGELSSLVRLQPQG
CCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCC
QAAPFFCIHPMSGMANVYAALAQLLGTQRPFYGVQAFGLEYPEMPLDDITVMAQRYLSDI
CCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHEECCCCCCCCHHHHHHHHHHHHHHH
RQVQPQGPYLLGGWSMGGSIAFEIASQLVAQGETVSLLALIDTPAKLTGTSPATLTDLEL
HHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHH
LIAMLGVDANILGIDDPKAEASEAVWNELLSIIKQHLGLPESYTLQRLRHLVSTFRTHSQ
HHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AVWNYQPANYPNDVLILRAADLAGEHDDQLNEAYRIADLGWSQFVTGQIQVQTIPGTHNT
HEECCCCCCCCCCEEEEEEHHHCCCCCHHHHHHHHHHHCCHHHEEECEEEEEECCCCCHH
LLNEPSLPILASHLAVALHNVAANTSLTPSHHEGSNEIAIMD
HCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2024119; 1740151 [H]