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The map label for this gene is lgrC [H]

Identifier: 159898936

GI number: 159898936

Start: 3091811

End: 3095194

Strand: Direct

Name: lgrC [H]

Synonym: Haur_2415

Alternate gene names: 159898936

Gene position: 3091811-3095194 (Clockwise)

Preceding gene: 159898935

Following gene: 159898937

Centisome position: 48.72

GC content: 50.68

Gene sequence:

>3384_bases
GTGAGCGATTATTCTGAGCGTTTAGCGGCACTTTCGCCAGCCAAACGGGCCTTACTTTTGCAAAAAATTCAAGACAAAGC
CAATAAAGCCGCCCAACAGATTCAGCCAAGGCTTGATCAAAACAGCTATCCGTTGTCGTTTGCTCAACAACGGCTCTGGC
TGATCGAGCAACTTCAGCCCAACGCGGCTTTATACAACATTTCAATTCCAATTCTGATTCGCGGCGTTTACCCTGAATTG
CCGAGCATTTTGACCCAGTGTTTGACCACGATTTTCCAACGCCATGAGCCATTACGTGCCAGTTTCAGCATGGTCGATGG
CCTTCCCCAGCAATCAATTATGGCCTTGGAAAGCGTCGAATTACCGATTGTTGATCTACGTGAATTAACCCCAAGCGAGC
GTGAAGCCGCCGTACATCAATTTATGCAAGCTGAAACTGAACGCCCGTTTGATTTGCGTCATGATCAACTGTTTCGGGCC
AATTTGCTACGCATCAGTCCCGACGAGCATCTTTTATTGCTAATCATTCATCACATTGCCTTTGATGCGTGGTCAGTCAA
GATCTTTATCCAAGAATTTGAGGCGATTTTTACGGCCTTGGAAAATCAACAGCCGTTGCCGCAATTCGAGCCATTGGCCT
TGCAATATGCCGATTTTGCTGCTTGGCAACGCGAATGGTTGCAAGGTGCAACTCTCAATCAACAACTCAGCTATTGGAAA
AACCAGCTTGCTGGTGAATTGCCAGTGCTGGCCTTGCCAACCGATCGCCCACGCCCAGCCATTCAAACCTTCAAAGGCGG
TCGCCATACCTTTTGGATCAGCACCGAACTAACCAATCAACTCAATCAGCTCAGCCAACAGCACCAAGCAACTCTATTTA
TGCTGTTGCTCGGCGCATGGGTCAGCTTACTCCATCGCTACAGCGGCCAAAACGACATCATTGTTGGTTCACCGATCGCC
AACCGCAATCGGCGTGAGCTAGAAGATCTGATCGGCTTTTTCGTCAATACCTTGGTGCTGCGAGTCAAATGTGCTGATGA
TCCAAGCTTCCTCGATTTGCTGGAGCATGTGCGTGCAGTAGCGCTGGGAGCCTACGCCCACCAAGACTTGCCGTTTGAAA
TGTTGGTCGATGCCCTGCAACCAACTCGCGATCTGAGCCGTTCAGCGCTCTTTCAGGTGTTGTTTGTGCTGCAAAATGTT
TCGATCGGCGGTCAGCATTCAGCCTTCGATATTTTGGAAGATGTGGCTAGCCCTTCAAAATTCGATCTCACACTGTCGAT
GTTTGAGTTTGAGCAGGGTTTACGCGCAACAATTGAATACAATGTTGATCTGTTTGATGCCAGCACGATCGACCGCATGA
GTCAACATTATGTCACATTGCTCAGCAGCATCAATCAACAACCGCAAACCAAACTTTCACAATTGGCAATGCTCACGGCG
GCTGAGCAAACCCAAATCATCAAAACTTGGAACAACACCAGCCAAACCTACCCTGAGCAGCTTACATTTGCCCAACTATT
TGAGGCTCAAGTTGCCAAAACACCTGAAGCAACTGCCCTGATTGGCGAAGATCAGGTGCTCAGCTATCACGAACTTAATC
GCCGTGCCAATCAATTGGCCTATCGGTTGCAAGCCCAAGGTGTTGGCCCCGAAAGCTTGGTTGGCATCTGTTGCGATCGC
TCAATTGCGATGGTGGTTGCGTTATTGGCCACGCTCAAATCCGGCGGCGCGTATATCCCGCTTGATCCAGCTTACCCCAA
CGAGCGTTTGGCTTGGATGCTCAACGATTCGCAAGCAGCACTAGTTTTGACCCAAAGCCATTTGCTTGAAAAAGTACAAC
AACTCAAGCAGGCTGATTTAACCGTGCTTGATCTGGCGAAGATTTGCGATGGCAATGAGCCAAGCCAAAATCTTGTCAGT
GCTGTTCAGCCCGCCAACTTAGCCTATATCGTCTATACCTCTGGCTCAACTGGCCAGCCCAAAGGCGTGATGGCTAGCCA
GCAAGGCTTAACCAACTTGGTAACAGCCCAAATTGCCGGCTTTGGGGTAACCTCAGCAAGTCGGGTGTTGCAATTTGCTT
CGTTCAGTTTCGATGCGGCGATCTCCGAGATTGGCATGGCGTTGGCTTCAGGCGCAAGTTTGGTGCTCATGCCAGCAGGT
GGCCTAGCCGCCGGAACCGATGTGCTAGCATTGATTCGCCAACACAACATTACGGTAGCGACCTTGCCACCATCATTATT
AGCAGTGCTTTCAGCGGATCAAGCTCCCAGTTTGACCACAGTAATTGCTGCTGGCGAGGCTTCGAGCAATGAGGTTGTGC
AACGCTGGGCAGTTGAGCGCAATTTAATCAACGCCTATGGGCCAAGTGAAACCACAGTTTGCGCGAGCCTGACTCGGCTT
GAGCCAAATCTGGCAGGTACGCCACCGATTGGCCGACCACTAGCCAATTTACAAGTCTATTTGCTCGATCAACAGCAGCA
GATCGTGCCCGTTGGCGTGATTGGCGAAATCTATGTTGGCGGGGTTGGTGTAGCCCGTGGCTATCTGAAACGGCCCGCTC
TGACCGCCGAGCGCTTTATTCCCAACCAATTTAGCTCAACTCCAGGCCAACGTTTGTATCGCACTGGCGATTTAGGCCGC
TATCGGGTTGATGGCCAAATTGAATTTGTTGGGCGGATCGATCAGCAGATCAAATTACGCGGCCATCGGATCGAGCTAGG
CGAAATTAGTAGCCTGCTGAATGCTCACCCAGCAGTCGAGCAAAGTGTGGTGTTGGTGCACGATCACGCTAGCAGCACGG
CGCGGCTGATTGCCTATGTTGTGGCAAATAGCACCAGCAGCAATGCTCTCAGCGAATTGCAAATCGCCGCAGGAACCAGC
CAAGCACCAGCAAGCTACGATTTAGCGGCAGATTTACAAGCCTATGCCAAGCAAAAACTGCCAGCATTTGCCGTGCCTAG
TGCCTTCGTGGTGTTGCCAAGCATGCCACTAACGCCCAACGGCAAGATCGATCAGCGCAAATTGGCCGAGCACACCCCCA
ACCCAAATCCAGCTACGAGTGTTGATGTTGTACCCCAAACCAACCTTGAACAAACCTTGACCACACTTTGGCAAGAAGTA
TTAAATGTGCCAACCCTAAGCACCCAAGCCAATTTCTTCGACCTTGGCGGCAATTCGCTGGCAATGGTGCAGGTGCATAG
CCGCTTGCAAGAGCTTTTGGGGCGCGAGTTGGTGCTTTTAGATTTATTCAAATACCCAACCATTCAAAGTTTAGCGGTTT
ACTTGAACAGCGAGCAATCAACTCAAGCGTCAACCTTTGTTGATCGCGACAATCGAGCGCAGCAACAGCGCCAAGCTATG
CAACGTCAACGTCGCCGCCGCTAG

Upstream 100 bases:

>100_bases
TAGATCATGCTAGAGGGTTCCCACTCGCCTCGCGGGCGGGAGAGGAGGCTAGGGGGTGAGGGAATACATAGGTAGTTTTG
TGTGTAGTTGAGGTTTGATT

Downstream 100 bases:

>100_bases
CAGAGAGGAATATATCGATGAGTTATGATGAAACCGATGGCAATTTTGATATTGCTGTGGTAGGTTTGGCGGGGCGCTGG
GCTGGCGCTCCCGATATTGA

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1127; Mature: 1126

Protein sequence:

>1127_residues
MSDYSERLAALSPAKRALLLQKIQDKANKAAQQIQPRLDQNSYPLSFAQQRLWLIEQLQPNAALYNISIPILIRGVYPEL
PSILTQCLTTIFQRHEPLRASFSMVDGLPQQSIMALESVELPIVDLRELTPSEREAAVHQFMQAETERPFDLRHDQLFRA
NLLRISPDEHLLLLIIHHIAFDAWSVKIFIQEFEAIFTALENQQPLPQFEPLALQYADFAAWQREWLQGATLNQQLSYWK
NQLAGELPVLALPTDRPRPAIQTFKGGRHTFWISTELTNQLNQLSQQHQATLFMLLLGAWVSLLHRYSGQNDIIVGSPIA
NRNRRELEDLIGFFVNTLVLRVKCADDPSFLDLLEHVRAVALGAYAHQDLPFEMLVDALQPTRDLSRSALFQVLFVLQNV
SIGGQHSAFDILEDVASPSKFDLTLSMFEFEQGLRATIEYNVDLFDASTIDRMSQHYVTLLSSINQQPQTKLSQLAMLTA
AEQTQIIKTWNNTSQTYPEQLTFAQLFEAQVAKTPEATALIGEDQVLSYHELNRRANQLAYRLQAQGVGPESLVGICCDR
SIAMVVALLATLKSGGAYIPLDPAYPNERLAWMLNDSQAALVLTQSHLLEKVQQLKQADLTVLDLAKICDGNEPSQNLVS
AVQPANLAYIVYTSGSTGQPKGVMASQQGLTNLVTAQIAGFGVTSASRVLQFASFSFDAAISEIGMALASGASLVLMPAG
GLAAGTDVLALIRQHNITVATLPPSLLAVLSADQAPSLTTVIAAGEASSNEVVQRWAVERNLINAYGPSETTVCASLTRL
EPNLAGTPPIGRPLANLQVYLLDQQQQIVPVGVIGEIYVGGVGVARGYLKRPALTAERFIPNQFSSTPGQRLYRTGDLGR
YRVDGQIEFVGRIDQQIKLRGHRIELGEISSLLNAHPAVEQSVVLVHDHASSTARLIAYVVANSTSSNALSELQIAAGTS
QAPASYDLAADLQAYAKQKLPAFAVPSAFVVLPSMPLTPNGKIDQRKLAEHTPNPNPATSVDVVPQTNLEQTLTTLWQEV
LNVPTLSTQANFFDLGGNSLAMVQVHSRLQELLGRELVLLDLFKYPTIQSLAVYLNSEQSTQASTFVDRDNRAQQQRQAM
QRQRRRR

Sequences:

>Translated_1127_residues
MSDYSERLAALSPAKRALLLQKIQDKANKAAQQIQPRLDQNSYPLSFAQQRLWLIEQLQPNAALYNISIPILIRGVYPEL
PSILTQCLTTIFQRHEPLRASFSMVDGLPQQSIMALESVELPIVDLRELTPSEREAAVHQFMQAETERPFDLRHDQLFRA
NLLRISPDEHLLLLIIHHIAFDAWSVKIFIQEFEAIFTALENQQPLPQFEPLALQYADFAAWQREWLQGATLNQQLSYWK
NQLAGELPVLALPTDRPRPAIQTFKGGRHTFWISTELTNQLNQLSQQHQATLFMLLLGAWVSLLHRYSGQNDIIVGSPIA
NRNRRELEDLIGFFVNTLVLRVKCADDPSFLDLLEHVRAVALGAYAHQDLPFEMLVDALQPTRDLSRSALFQVLFVLQNV
SIGGQHSAFDILEDVASPSKFDLTLSMFEFEQGLRATIEYNVDLFDASTIDRMSQHYVTLLSSINQQPQTKLSQLAMLTA
AEQTQIIKTWNNTSQTYPEQLTFAQLFEAQVAKTPEATALIGEDQVLSYHELNRRANQLAYRLQAQGVGPESLVGICCDR
SIAMVVALLATLKSGGAYIPLDPAYPNERLAWMLNDSQAALVLTQSHLLEKVQQLKQADLTVLDLAKICDGNEPSQNLVS
AVQPANLAYIVYTSGSTGQPKGVMASQQGLTNLVTAQIAGFGVTSASRVLQFASFSFDAAISEIGMALASGASLVLMPAG
GLAAGTDVLALIRQHNITVATLPPSLLAVLSADQAPSLTTVIAAGEASSNEVVQRWAVERNLINAYGPSETTVCASLTRL
EPNLAGTPPIGRPLANLQVYLLDQQQQIVPVGVIGEIYVGGVGVARGYLKRPALTAERFIPNQFSSTPGQRLYRTGDLGR
YRVDGQIEFVGRIDQQIKLRGHRIELGEISSLLNAHPAVEQSVVLVHDHASSTARLIAYVVANSTSSNALSELQIAAGTS
QAPASYDLAADLQAYAKQKLPAFAVPSAFVVLPSMPLTPNGKIDQRKLAEHTPNPNPATSVDVVPQTNLEQTLTTLWQEV
LNVPTLSTQANFFDLGGNSLAMVQVHSRLQELLGRELVLLDLFKYPTIQSLAVYLNSEQSTQASTFVDRDNRAQQQRQAM
QRQRRRR
>Mature_1126_residues
SDYSERLAALSPAKRALLLQKIQDKANKAAQQIQPRLDQNSYPLSFAQQRLWLIEQLQPNAALYNISIPILIRGVYPELP
SILTQCLTTIFQRHEPLRASFSMVDGLPQQSIMALESVELPIVDLRELTPSEREAAVHQFMQAETERPFDLRHDQLFRAN
LLRISPDEHLLLLIIHHIAFDAWSVKIFIQEFEAIFTALENQQPLPQFEPLALQYADFAAWQREWLQGATLNQQLSYWKN
QLAGELPVLALPTDRPRPAIQTFKGGRHTFWISTELTNQLNQLSQQHQATLFMLLLGAWVSLLHRYSGQNDIIVGSPIAN
RNRRELEDLIGFFVNTLVLRVKCADDPSFLDLLEHVRAVALGAYAHQDLPFEMLVDALQPTRDLSRSALFQVLFVLQNVS
IGGQHSAFDILEDVASPSKFDLTLSMFEFEQGLRATIEYNVDLFDASTIDRMSQHYVTLLSSINQQPQTKLSQLAMLTAA
EQTQIIKTWNNTSQTYPEQLTFAQLFEAQVAKTPEATALIGEDQVLSYHELNRRANQLAYRLQAQGVGPESLVGICCDRS
IAMVVALLATLKSGGAYIPLDPAYPNERLAWMLNDSQAALVLTQSHLLEKVQQLKQADLTVLDLAKICDGNEPSQNLVSA
VQPANLAYIVYTSGSTGQPKGVMASQQGLTNLVTAQIAGFGVTSASRVLQFASFSFDAAISEIGMALASGASLVLMPAGG
LAAGTDVLALIRQHNITVATLPPSLLAVLSADQAPSLTTVIAAGEASSNEVVQRWAVERNLINAYGPSETTVCASLTRLE
PNLAGTPPIGRPLANLQVYLLDQQQQIVPVGVIGEIYVGGVGVARGYLKRPALTAERFIPNQFSSTPGQRLYRTGDLGRY
RVDGQIEFVGRIDQQIKLRGHRIELGEISSLLNAHPAVEQSVVLVHDHASSTARLIAYVVANSTSSNALSELQIAAGTSQ
APASYDLAADLQAYAKQKLPAFAVPSAFVVLPSMPLTPNGKIDQRKLAEHTPNPNPATSVDVVPQTNLEQTLTTLWQEVL
NVPTLSTQANFFDLGGNSLAMVQVHSRLQELLGRELVLLDLFKYPTIQSLAVYLNSEQSTQASTFVDRDNRAQQQRQAMQ
RQRRRR

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=455, Percent_Identity=27.2527472527473, Blast_Score=118, Evalue=3e-26,
Organism=Homo sapiens, GI28416953, Length=580, Percent_Identity=23.448275862069, Blast_Score=94, Evalue=7e-19,
Organism=Homo sapiens, GI38505220, Length=572, Percent_Identity=22.9020979020979, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI42544132, Length=562, Percent_Identity=22.2419928825623, Blast_Score=85, Evalue=4e-16,
Organism=Homo sapiens, GI122937307, Length=382, Percent_Identity=25.130890052356, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI58082049, Length=535, Percent_Identity=23.1775700934579, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI157311624, Length=535, Percent_Identity=22.9906542056075, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI157311622, Length=535, Percent_Identity=22.9906542056075, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI195947378, Length=379, Percent_Identity=24.5382585751979, Blast_Score=70, Evalue=1e-11,
Organism=Escherichia coli, GI1786801, Length=1102, Percent_Identity=28.1306715063521, Blast_Score=305, Evalue=8e-84,
Organism=Escherichia coli, GI221142682, Length=532, Percent_Identity=24.4360902255639, Blast_Score=109, Evalue=9e-25,
Organism=Escherichia coli, GI1786810, Length=532, Percent_Identity=25.3759398496241, Blast_Score=93, Evalue=8e-20,
Organism=Escherichia coli, GI145693145, Length=512, Percent_Identity=23.2421875, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17556356, Length=577, Percent_Identity=27.3830155979203, Blast_Score=180, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17550940, Length=1085, Percent_Identity=20.8294930875576, Blast_Score=165, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17538037, Length=526, Percent_Identity=23.384030418251, Blast_Score=102, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17560140, Length=483, Percent_Identity=22.1532091097308, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17531443, Length=477, Percent_Identity=21.8029350104822, Blast_Score=81, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17559526, Length=342, Percent_Identity=24.2690058479532, Blast_Score=77, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6319591, Length=922, Percent_Identity=24.5119305856833, Blast_Score=257, Evalue=9e-69,
Organism=Saccharomyces cerevisiae, GI6319699, Length=230, Percent_Identity=24.3478260869565, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648676, Length=626, Percent_Identity=29.7124600638978, Blast_Score=204, Evalue=4e-52,
Organism=Drosophila melanogaster, GI24581924, Length=546, Percent_Identity=23.4432234432234, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24667955, Length=554, Percent_Identity=21.841155234657, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI62472339, Length=554, Percent_Identity=21.6606498194946, Blast_Score=91, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24667959, Length=389, Percent_Identity=23.9074550128535, Blast_Score=90, Evalue=8e-18,
Organism=Drosophila melanogaster, GI21355181, Length=515, Percent_Identity=21.5533980582524, Blast_Score=77, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24582852, Length=516, Percent_Identity=22.093023255814, Blast_Score=74, Evalue=8e-13,
Organism=Drosophila melanogaster, GI281365686, Length=483, Percent_Identity=22.9813664596273, Blast_Score=71, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 124371; Mature: 124239

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYSERLAALSPAKRALLLQKIQDKANKAAQQIQPRLDQNSYPLSFAQQRLWLIEQLQP
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
NAALYNISIPILIRGVYPELPSILTQCLTTIFQRHEPLRASFSMVDGLPQQSIMALESVE
CCEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHCC
LPIVDLRELTPSEREAAVHQFMQAETERPFDLRHDQLFRANLLRISPDEHLLLLIIHHIA
CCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCEEECCCCHHHHHHHHHHH
FDAWSVKIFIQEFEAIFTALENQQPLPQFEPLALQYADFAAWQREWLQGATLNQQLSYWK
HCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
NQLAGELPVLALPTDRPRPAIQTFKGGRHTFWISTELTNQLNQLSQQHQATLFMLLLGAW
HHHCCCCCEEECCCCCCCHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
VSLLHRYSGQNDIIVGSPIANRNRRELEDLIGFFVNTLVLRVKCADDPSFLDLLEHVRAV
HHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHH
ALGAYAHQDLPFEMLVDALQPTRDLSRSALFQVLFVLQNVSIGGQHSAFDILEDVASPSK
HHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
FDLTLSMFEFEQGLRATIEYNVDLFDASTIDRMSQHYVTLLSSINQQPQTKLSQLAMLTA
EEEEEEHHHHHCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AEQTQIIKTWNNTSQTYPEQLTFAQLFEAQVAKTPEATALIGEDQVLSYHELNRRANQLA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHH
YRLQAQGVGPESLVGICCDRSIAMVVALLATLKSGGAYIPLDPAYPNERLAWMLNDSQAA
HHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEEECCCCEE
LVLTQSHLLEKVQQLKQADLTVLDLAKICDGNEPSQNLVSAVQPANLAYIVYTSGSTGQP
EEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEEECCCCCCC
KGVMASQQGLTNLVTAQIAGFGVTSASRVLQFASFSFDAAISEIGMALASGASLVLMPAG
CCCCCHHHCHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCC
GLAAGTDVLALIRQHNITVATLPPSLLAVLSADQAPSLTTVIAAGEASSNEVVQRWAVER
CCCHHHHHHHHHHHCCEEEEECCHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
NLINAYGPSETTVCASLTRLEPNLAGTPPIGRPLANLQVYLLDQQQQIVPVGVIGEIYVG
HHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECHHHCC
GVGVARGYLKRPALTAERFIPNQFSSTPGQRLYRTGDLGRYRVDGQIEFVGRIDQQIKLR
CHHHHHHHHHCCCCHHHHHCCCCCCCCCCHHHEECCCCCEEEECCEEEEEECCCHHHHHC
GHRIELGEISSLLNAHPAVEQSVVLVHDHASSTARLIAYVVANSTSSNALSELQIAAGTS
CCEEEHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHEECCCC
QAPASYDLAADLQAYAKQKLPAFAVPSAFVVLPSMPLTPNGKIDQRKLAEHTPNPNPATS
CCCCCCCHHHHHHHHHHHCCCCEECCCCEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCE
VDVVPQTNLEQTLTTLWQEVLNVPTLSTQANFFDLGGNSLAMVQVHSRLQELLGRELVLL
EEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEHHHHHHHHHHHHCCCEEEH
DLFKYPTIQSLAVYLNSEQSTQASTFVDRDNRAQQQRQAMQRQRRRR
HHHCCCCHHHHHHEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDYSERLAALSPAKRALLLQKIQDKANKAAQQIQPRLDQNSYPLSFAQQRLWLIEQLQP
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
NAALYNISIPILIRGVYPELPSILTQCLTTIFQRHEPLRASFSMVDGLPQQSIMALESVE
CCEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHCC
LPIVDLRELTPSEREAAVHQFMQAETERPFDLRHDQLFRANLLRISPDEHLLLLIIHHIA
CCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCEEECCCCHHHHHHHHHHH
FDAWSVKIFIQEFEAIFTALENQQPLPQFEPLALQYADFAAWQREWLQGATLNQQLSYWK
HCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
NQLAGELPVLALPTDRPRPAIQTFKGGRHTFWISTELTNQLNQLSQQHQATLFMLLLGAW
HHHCCCCCEEECCCCCCCHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
VSLLHRYSGQNDIIVGSPIANRNRRELEDLIGFFVNTLVLRVKCADDPSFLDLLEHVRAV
HHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHH
ALGAYAHQDLPFEMLVDALQPTRDLSRSALFQVLFVLQNVSIGGQHSAFDILEDVASPSK
HHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
FDLTLSMFEFEQGLRATIEYNVDLFDASTIDRMSQHYVTLLSSINQQPQTKLSQLAMLTA
EEEEEEHHHHHCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AEQTQIIKTWNNTSQTYPEQLTFAQLFEAQVAKTPEATALIGEDQVLSYHELNRRANQLA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHH
YRLQAQGVGPESLVGICCDRSIAMVVALLATLKSGGAYIPLDPAYPNERLAWMLNDSQAA
HHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEEECCCCEE
LVLTQSHLLEKVQQLKQADLTVLDLAKICDGNEPSQNLVSAVQPANLAYIVYTSGSTGQP
EEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEEECCCCCCC
KGVMASQQGLTNLVTAQIAGFGVTSASRVLQFASFSFDAAISEIGMALASGASLVLMPAG
CCCCCHHHCHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCC
GLAAGTDVLALIRQHNITVATLPPSLLAVLSADQAPSLTTVIAAGEASSNEVVQRWAVER
CCCHHHHHHHHHHHCCEEEEECCHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
NLINAYGPSETTVCASLTRLEPNLAGTPPIGRPLANLQVYLLDQQQQIVPVGVIGEIYVG
HHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECHHHCC
GVGVARGYLKRPALTAERFIPNQFSSTPGQRLYRTGDLGRYRVDGQIEFVGRIDQQIKLR
CHHHHHHHHHCCCCHHHHHCCCCCCCCCCHHHEECCCCCEEEECCEEEEEECCCHHHHHC
GHRIELGEISSLLNAHPAVEQSVVLVHDHASSTARLIAYVVANSTSSNALSELQIAAGTS
CCEEEHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHEECCCC
QAPASYDLAADLQAYAKQKLPAFAVPSAFVVLPSMPLTPNGKIDQRKLAEHTPNPNPATS
CCCCCCCHHHHHHHHHHHCCCCEECCCCEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCE
VDVVPQTNLEQTLTTLWQEVLNVPTLSTQANFFDLGGNSLAMVQVHSRLQELLGRELVLL
EEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEHHHHHHHHHHHHCCCEEEH
DLFKYPTIQSLAVYLNSEQSTQASTFVDRDNRAQQQRQAMQRQRRRR
HHHCCCCHHHHHHEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA