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The map label for this gene is pkn1 [H]

Identifier: 159898902

GI number: 159898902

Start: 3033183

End: 3034628

Strand: Reverse

Name: pkn1 [H]

Synonym: Haur_2381

Alternate gene names: 159898902

Gene position: 3034628-3033183 (Counterclockwise)

Preceding gene: 159898909

Following gene: 159898900

Centisome position: 47.82

GC content: 49.31

Gene sequence:

>1446_bases
ATGGCTGATATCACCAATCGTCAGCAGTTTTGTCGGGCAGTCGGGGATGGGTTAAAGTTAGTCCAAAGTCAACGAAGTGG
CTCCATGCCAAGTACAGAAGCGTATATAGCCGATTGCTTGAGCATTGGGGTTGATACACTCCGTACATTACGCTATGCTT
CCCGTCAACGCGTGATGGTCGAAGATAAAACTTTAGCCGCATTAATTTGGATTGTCCTGGCCGAAGGTCGGGCAACTCAA
CCATGGCTGATCACAATGCTCAGTGCGACTAGTATTATTCCCCCCGAACCACTGACAACTACTTGGCTTGAGAGCTATCT
GCAAAGTGGTTTCAAACAACAACTCGATCAAGCATTGCTGAGCCAGGTTGTCCAAAGCATTCTTCCTAACCAAGCTCCAA
GTGTCCTCAATCTCGTTGTTGATACCCAAATCGATGCATCAGATTTGCCCTTAAATCTTCCAACCCCAGCGCCGAGTATT
CAAGTTAAATCAAAATTTCCCAACAAACCGTACCAGTGGTTGGGCTTATTTGGGCTGATCAGTGTGCTTGGCTGGCCGCT
GTTTTCATTATTTCAAGCAACTGCGGCATCTCATGATGCTTCAAGCAGCATGGCCTTAATTCCTGCTGATGAATATTTGC
AAGGCAGTAGTGATGCTGATATTGCTGAATATACGCGTTTGTGCCAAGTGCATCAGACAGGCTGCGATAGCTCGTGGTTT
GCCGATGAACAACCACAGCGTTTGATTCAACTTGATGCCTTTGCCATCGATCGCTTTGAGGTCAGCAATCGCGATTTTCT
GCGTTATAGTGAGGCTAACCCCAGCCTCTTAACCCAAGCTGAAACGCAGGGGGCAGGCTTTGTCTGGAGCGATAGTAATG
GTTTCGAGTTGATCAATGGAGCAAATTGGCGGCATCCTCATGGTCCAAATTCAGCAATTACTGAACATTTGGATAAACCA
GTGGTGCAAATAACGCCCAGTGAAGCCCAAGCCTATTGTATTTGGCAAGGCAAACGCCTGCCAACCGAGGCCGAATGGGA
GGTAGCAGCCCGTGGTAAGCATTATTGGCGCTTTCCTTGGGGCAACGATTGGCAGCCCGCTAAGCTCAATTTTACCCAAG
GCAAGCTTAGCCCAGCCTTGATGAACGTAGATAGCCTACCCGAGGGTCAAAGTTTTTATGGGGTGGCGCATATGCTTGGC
AATGCTGCTGAATGGACTGCCGATTGGTATGATCCGCATGCCTGTCAGTCCAACGATCGGCTTAATCCACGTGGGCCAGT
GATTCCAACTGCCCGGCATACCCGCCGAGGTGGCTCGGTCGCTAGCATGGCCGGAGTTTTGCATAGCACCTGGCGGATTA
GCAACGAGCAAATTAACGATCAACCAAGCAATGGCACAGGCTTTCGCTGTGTCCAACATATCGCACTAGATCAGAGCTTG
CCATGA

Upstream 100 bases:

>100_bases
GAGCTACAGACTTCTCTGAAATATTACAGCAGAGGATTTAAAATGGTATAGATATGCGGTAAGCTAGCAGTGTTTGATCG
TGCTTAATGGAGGTAGCACA

Downstream 100 bases:

>100_bases
TTGCAAAAGAGTGGCTCTTTAACCACTAAAGGGGATGCTAGGCTAGCTAGCATCCCCTCGCCTAACACTTTTTAATTAGT
TAAGTTGATTAACCGCCCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MADITNRQQFCRAVGDGLKLVQSQRSGSMPSTEAYIADCLSIGVDTLRTLRYASRQRVMVEDKTLAALIWIVLAEGRATQ
PWLITMLSATSIIPPEPLTTTWLESYLQSGFKQQLDQALLSQVVQSILPNQAPSVLNLVVDTQIDASDLPLNLPTPAPSI
QVKSKFPNKPYQWLGLFGLISVLGWPLFSLFQATAASHDASSSMALIPADEYLQGSSDADIAEYTRLCQVHQTGCDSSWF
ADEQPQRLIQLDAFAIDRFEVSNRDFLRYSEANPSLLTQAETQGAGFVWSDSNGFELINGANWRHPHGPNSAITEHLDKP
VVQITPSEAQAYCIWQGKRLPTEAEWEVAARGKHYWRFPWGNDWQPAKLNFTQGKLSPALMNVDSLPEGQSFYGVAHMLG
NAAEWTADWYDPHACQSNDRLNPRGPVIPTARHTRRGGSVASMAGVLHSTWRISNEQINDQPSNGTGFRCVQHIALDQSL
P

Sequences:

>Translated_481_residues
MADITNRQQFCRAVGDGLKLVQSQRSGSMPSTEAYIADCLSIGVDTLRTLRYASRQRVMVEDKTLAALIWIVLAEGRATQ
PWLITMLSATSIIPPEPLTTTWLESYLQSGFKQQLDQALLSQVVQSILPNQAPSVLNLVVDTQIDASDLPLNLPTPAPSI
QVKSKFPNKPYQWLGLFGLISVLGWPLFSLFQATAASHDASSSMALIPADEYLQGSSDADIAEYTRLCQVHQTGCDSSWF
ADEQPQRLIQLDAFAIDRFEVSNRDFLRYSEANPSLLTQAETQGAGFVWSDSNGFELINGANWRHPHGPNSAITEHLDKP
VVQITPSEAQAYCIWQGKRLPTEAEWEVAARGKHYWRFPWGNDWQPAKLNFTQGKLSPALMNVDSLPEGQSFYGVAHMLG
NAAEWTADWYDPHACQSNDRLNPRGPVIPTARHTRRGGSVASMAGVLHSTWRISNEQINDQPSNGTGFRCVQHIALDQSL
P
>Mature_480_residues
ADITNRQQFCRAVGDGLKLVQSQRSGSMPSTEAYIADCLSIGVDTLRTLRYASRQRVMVEDKTLAALIWIVLAEGRATQP
WLITMLSATSIIPPEPLTTTWLESYLQSGFKQQLDQALLSQVVQSILPNQAPSVLNLVVDTQIDASDLPLNLPTPAPSIQ
VKSKFPNKPYQWLGLFGLISVLGWPLFSLFQATAASHDASSSMALIPADEYLQGSSDADIAEYTRLCQVHQTGCDSSWFA
DEQPQRLIQLDAFAIDRFEVSNRDFLRYSEANPSLLTQAETQGAGFVWSDSNGFELINGANWRHPHGPNSAITEHLDKPV
VQITPSEAQAYCIWQGKRLPTEAEWEVAARGKHYWRFPWGNDWQPAKLNFTQGKLSPALMNVDSLPEGQSFYGVAHMLGN
AAEWTADWYDPHACQSNDRLNPRGPVIPTARHTRRGGSVASMAGVLHSTWRISNEQINDQPSNGTGFRCVQHIALDQSLP

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=304, Percent_Identity=33.5526315789474, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI257470975, Length=288, Percent_Identity=34.375, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI257470977, Length=253, Percent_Identity=35.1778656126482, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI194248088, Length=255, Percent_Identity=36.8627450980392, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI194248087, Length=240, Percent_Identity=38.3333333333333, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI194248090, Length=171, Percent_Identity=39.766081871345, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI226437577, Length=184, Percent_Identity=39.1304347826087, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI20130397, Length=260, Percent_Identity=31.1538461538462, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 53302; Mature: 53171

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADITNRQQFCRAVGDGLKLVQSQRSGSMPSTEAYIADCLSIGVDTLRTLRYASRQRVMV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
EDKTLAALIWIVLAEGRATQPWLITMLSATSIIPPEPLTTTWLESYLQSGFKQQLDQALL
CHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SQVVQSILPNQAPSVLNLVVDTQIDASDLPLNLPTPAPSIQVKSKFPNKPYQWLGLFGLI
HHHHHHHCCCCCCCCEEEEEECCCCCCCCCEECCCCCCCEEECCCCCCCHHHHHHHHHHH
SVLGWPLFSLFQATAASHDASSSMALIPADEYLQGSSDADIAEYTRLCQVHQTGCDSSWF
HHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCC
ADEQPQRLIQLDAFAIDRFEVSNRDFLRYSEANPSLLTQAETQGAGFVWSDSNGFELING
CCCCHHHHHHHHHHEEEEEECCCCCEEEECCCCCCCEEECCCCCCCEEEECCCCCEEECC
ANWRHPHGPNSAITEHLDKPVVQITPSEAQAYCIWQGKRLPTEAEWEVAARGKHYWRFPW
CCCCCCCCCCHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCCCCHHCCCCCEEEECCC
GNDWQPAKLNFTQGKLSPALMNVDSLPEGQSFYGVAHMLGNAAEWTADWYDPHACQSNDR
CCCCCCCEEECCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCHHCCCCCCCCCCCCCCCC
LNPRGPVIPTARHTRRGGSVASMAGVLHSTWRISNEQINDQPSNGTGFRCVQHIALDQSL
CCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
P
C
>Mature Secondary Structure 
ADITNRQQFCRAVGDGLKLVQSQRSGSMPSTEAYIADCLSIGVDTLRTLRYASRQRVMV
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
EDKTLAALIWIVLAEGRATQPWLITMLSATSIIPPEPLTTTWLESYLQSGFKQQLDQALL
CHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SQVVQSILPNQAPSVLNLVVDTQIDASDLPLNLPTPAPSIQVKSKFPNKPYQWLGLFGLI
HHHHHHHCCCCCCCCEEEEEECCCCCCCCCEECCCCCCCEEECCCCCCCHHHHHHHHHHH
SVLGWPLFSLFQATAASHDASSSMALIPADEYLQGSSDADIAEYTRLCQVHQTGCDSSWF
HHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCC
ADEQPQRLIQLDAFAIDRFEVSNRDFLRYSEANPSLLTQAETQGAGFVWSDSNGFELING
CCCCHHHHHHHHHHEEEEEECCCCCEEEECCCCCCCEEECCCCCCCEEEECCCCCEEECC
ANWRHPHGPNSAITEHLDKPVVQITPSEAQAYCIWQGKRLPTEAEWEVAARGKHYWRFPW
CCCCCCCCCCHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCCCCHHCCCCCEEEECCC
GNDWQPAKLNFTQGKLSPALMNVDSLPEGQSFYGVAHMLGNAAEWTADWYDPHACQSNDR
CCCCCCCEEECCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCHHCCCCCCCCCCCCCCCC
LNPRGPVIPTARHTRRGGSVASMAGVLHSTWRISNEQINDQPSNGTGFRCVQHIALDQSL
CCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]