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The map label for this gene is resE [H]

Identifier: 159898878

GI number: 159898878

Start: 3004994

End: 3006370

Strand: Reverse

Name: resE [H]

Synonym: Haur_2357

Alternate gene names: 159898878

Gene position: 3006370-3004994 (Counterclockwise)

Preceding gene: 159898879

Following gene: 159898877

Centisome position: 47.37

GC content: 50.98

Gene sequence:

>1377_bases
ATGATGATGTTACGCTCACTGACATGGAAATTAACCCTCGCTTTTTTGGGGGTCGGCTTGATTGGGGCTGTGGTCGTGGC
CTTGTTGGCGCGGCAGAGTGCCCGCAGCGAGTTTGATCGCTTTTTATCCGAGCGCGATCAAACCGAATTAATCAACGCCG
TCACAACCTTTTATATGAGCTATTCGACGTGGGACGGCTTGGAATCGGCATTAAATCAAGAGGCTGATTTAGCTTTTTAT
CGCCGCAGTGCCACGCTGTTTGATCGTGATGGCAACGTGATTTTGGCCAACGGCCCGTATGTACCAGGCATGATTGCCGA
TCAAGCCACATTAAATGCGACTCAGCCTTTAACTGTTGCCAATCAAACTATTGGTTACATTGCTTTTGGCATGATCCAAA
CCGCCCAACCGCCAGCGCCAAGTGCTGATCAAATGATCAAAGATGGGCCGCGGCCCCAAGATTCGTTCGATCAACGGATT
ACCTGGGCAATTGGGGTCAGTGCGATTTTTGCTACGAGCGTAGCCTTGTTGGTGGGCACATTCTTGGCTCGTCGCCTAAC
CCGCTCGTTGCGCGAGTTGACGGTCGCGACCCAAGCTATGGCGGCTGGCCAGTTGGAGCAGCAAGTTGCGGTGCGTTCAA
ACGATGAAATTGGCGATTTGGCCCGTTCGTTTAATCATATGAGTGCCGATTTGAGCAAAGCCACCCATTTGCGCAAACAG
ATGACCGCTGATTTAGCTCATGATTTGCGCACGCCCTTGAGTATTTTGCGTGGCTATGCTGAGGGCTTGCGCGACGGCGT
TTTGCAACCATCAGAGACAATTTACACGGTGATTTTTGATGAAGTGACCCACCTACAACGCTTGGTTGACGATTTGCGGG
TGCTTTCGTTGGCCGATGCGGGCGAGCTTTCGCTTAATCGGCGCTTGGTTGATCCGGCGGCCTTGATCGAGCGCACGATT
TTGAGTGCCTTTGTGCAGGCTGAACGCCAAAATATCGAACTTAAATTAGAAACTGAAGCTGGCCTACCATCGGTTTCGGT
CGATACTGATCGCATGGCCCAAGTCTTGAATAATTTAGTTAATAATGCCCTGCGCCATACCAAACAAGGCAGTATTAGCC
TGATTGCCAAACGTCAAGCGCAGCAGGTGCAATTGATTATTCGCGATACTGGCAGCGGCATCGATCCTGCTGATGTGCCC
TACATTTTCGCGCGTTTCTATCGGGGCGATAGCTCGCGCCAACGTGAAGATCAAGCCTCGACAGGCTTGGGATTGGCGAT
TGTCAAGGCGATTGTTGAAGCGCATCAAGGCCAAATCGAGGTTGAATCAAGCTTGGGCGAAGGTACGAGCTTTATTATCA
GTTTACCGATTGCTTGA

Upstream 100 bases:

>100_bases
GCAATTTGCGCAGCAAAATCGAGCCAGACCCGAAAAATCCGCGCTATATCGAAACTGTGTATGGGGTTGGCTATCGTTTT
GCCCGCCCGAAACGGCCTGA

Downstream 100 bases:

>100_bases
CAATTAAGATATAATGAAACATATGTTCGTTTAGTAAGGGCGGGTTCAATGCAAATTAAAATGACCAGTGTTTTTGTCGA
TGATCAAACCAAGGCCTTGA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MMMLRSLTWKLTLAFLGVGLIGAVVVALLARQSARSEFDRFLSERDQTELINAVTTFYMSYSTWDGLESALNQEADLAFY
RRSATLFDRDGNVILANGPYVPGMIADQATLNATQPLTVANQTIGYIAFGMIQTAQPPAPSADQMIKDGPRPQDSFDQRI
TWAIGVSAIFATSVALLVGTFLARRLTRSLRELTVATQAMAAGQLEQQVAVRSNDEIGDLARSFNHMSADLSKATHLRKQ
MTADLAHDLRTPLSILRGYAEGLRDGVLQPSETIYTVIFDEVTHLQRLVDDLRVLSLADAGELSLNRRLVDPAALIERTI
LSAFVQAERQNIELKLETEAGLPSVSVDTDRMAQVLNNLVNNALRHTKQGSISLIAKRQAQQVQLIIRDTGSGIDPADVP
YIFARFYRGDSSRQREDQASTGLGLAIVKAIVEAHQGQIEVESSLGEGTSFIISLPIA

Sequences:

>Translated_458_residues
MMMLRSLTWKLTLAFLGVGLIGAVVVALLARQSARSEFDRFLSERDQTELINAVTTFYMSYSTWDGLESALNQEADLAFY
RRSATLFDRDGNVILANGPYVPGMIADQATLNATQPLTVANQTIGYIAFGMIQTAQPPAPSADQMIKDGPRPQDSFDQRI
TWAIGVSAIFATSVALLVGTFLARRLTRSLRELTVATQAMAAGQLEQQVAVRSNDEIGDLARSFNHMSADLSKATHLRKQ
MTADLAHDLRTPLSILRGYAEGLRDGVLQPSETIYTVIFDEVTHLQRLVDDLRVLSLADAGELSLNRRLVDPAALIERTI
LSAFVQAERQNIELKLETEAGLPSVSVDTDRMAQVLNNLVNNALRHTKQGSISLIAKRQAQQVQLIIRDTGSGIDPADVP
YIFARFYRGDSSRQREDQASTGLGLAIVKAIVEAHQGQIEVESSLGEGTSFIISLPIA
>Mature_458_residues
MMMLRSLTWKLTLAFLGVGLIGAVVVALLARQSARSEFDRFLSERDQTELINAVTTFYMSYSTWDGLESALNQEADLAFY
RRSATLFDRDGNVILANGPYVPGMIADQATLNATQPLTVANQTIGYIAFGMIQTAQPPAPSADQMIKDGPRPQDSFDQRI
TWAIGVSAIFATSVALLVGTFLARRLTRSLRELTVATQAMAAGQLEQQVAVRSNDEIGDLARSFNHMSADLSKATHLRKQ
MTADLAHDLRTPLSILRGYAEGLRDGVLQPSETIYTVIFDEVTHLQRLVDDLRVLSLADAGELSLNRRLVDPAALIERTI
LSAFVQAERQNIELKLETEAGLPSVSVDTDRMAQVLNNLVNNALRHTKQGSISLIAKRQAQQVQLIIRDTGSGIDPADVP
YIFARFYRGDSSRQREDQASTGLGLAIVKAIVEAHQGQIEVESSLGEGTSFIISLPIA

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=278, Percent_Identity=37.0503597122302, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786783, Length=297, Percent_Identity=30.3030303030303, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=32.5991189427313, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787894, Length=322, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=32.1266968325792, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790346, Length=272, Percent_Identity=29.7794117647059, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788713, Length=235, Percent_Identity=28.0851063829787, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790861, Length=339, Percent_Identity=29.2035398230088, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=26.25, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081816, Length=258, Percent_Identity=29.0697674418605, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789808, Length=300, Percent_Identity=28.3333333333333, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789149, Length=332, Percent_Identity=24.6987951807229, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790551, Length=279, Percent_Identity=29.0322580645161, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788549, Length=224, Percent_Identity=29.9107142857143, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=30.1724137931034, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI48994928, Length=229, Percent_Identity=26.2008733624454, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1788279, Length=305, Percent_Identity=27.2131147540984, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790300, Length=232, Percent_Identity=29.7413793103448, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87082128, Length=245, Percent_Identity=27.7551020408163, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789403, Length=292, Percent_Identity=25, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50131; Mature: 50131

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMMLRSLTWKLTLAFLGVGLIGAVVVALLARQSARSEFDRFLSERDQTELINAVTTFYMS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
YSTWDGLESALNQEADLAFYRRSATLFDRDGNVILANGPYVPGMIADQATLNATQPLTVA
HHHHHHHHHHHCCHHHHHHHHHCCCEEECCCCEEEECCCCCCCEECCCCCCCCCCCCHHH
NQTIGYIAFGMIQTAQPPAPSADQMIKDGPRPQDSFDQRITWAIGVSAIFATSVALLVGT
HHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FLARRLTRSLRELTVATQAMAAGQLEQQVAVRSNDEIGDLARSFNHMSADLSKATHLRKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MTADLAHDLRTPLSILRGYAEGLRDGVLQPSETIYTVIFDEVTHLQRLVDDLRVLSLADA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GELSLNRRLVDPAALIERTILSAFVQAERQNIELKLETEAGLPSVSVDTDRMAQVLNNLV
CCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
NNALRHTKQGSISLIAKRQAQQVQLIIRDTGSGIDPADVPYIFARFYRGDSSRQREDQAS
HHHHHHCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHH
TGLGLAIVKAIVEAHQGQIEVESSLGEGTSFIISLPIA
CCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECCCC
>Mature Secondary Structure
MMMLRSLTWKLTLAFLGVGLIGAVVVALLARQSARSEFDRFLSERDQTELINAVTTFYMS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
YSTWDGLESALNQEADLAFYRRSATLFDRDGNVILANGPYVPGMIADQATLNATQPLTVA
HHHHHHHHHHHCCHHHHHHHHHCCCEEECCCCEEEECCCCCCCEECCCCCCCCCCCCHHH
NQTIGYIAFGMIQTAQPPAPSADQMIKDGPRPQDSFDQRITWAIGVSAIFATSVALLVGT
HHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FLARRLTRSLRELTVATQAMAAGQLEQQVAVRSNDEIGDLARSFNHMSADLSKATHLRKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MTADLAHDLRTPLSILRGYAEGLRDGVLQPSETIYTVIFDEVTHLQRLVDDLRVLSLADA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GELSLNRRLVDPAALIERTILSAFVQAERQNIELKLETEAGLPSVSVDTDRMAQVLNNLV
CCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
NNALRHTKQGSISLIAKRQAQQVQLIIRDTGSGIDPADVPYIFARFYRGDSSRQREDQAS
HHHHHHCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHH
TGLGLAIVKAIVEAHQGQIEVESSLGEGTSFIISLPIA
CCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]