Click here to switch to the map view.

The map label for this gene is yjjA [H]

Identifier: 159898856

GI number: 159898856

Start: 2982294

End: 2983109

Strand: Direct

Name: yjjA [H]

Synonym: Haur_2335

Alternate gene names: 159898856

Gene position: 2982294-2983109 (Clockwise)

Preceding gene: 159898855

Following gene: 159898857

Centisome position: 46.99

GC content: 52.94

Gene sequence:

>816_bases
ATGAGTAGCTTACACGGTCAACGAATTGCAATTCTCGAAGCTCGCCGCGCTTCAGAATTAGCCAACTTGCTCAGTCGCCA
TGGTGCGAACCCAATCCATGCCCCAGCTTTACGCGAGGTCAGCGTCGATGCGGCTCCAGTCGCTCAGGCAGTGTTGCAAG
AGCTTGAAGCAGGCCAGATCGATCTGTTGATTTTGTTGACTGGGGTTGGCACGCAGCAATTAATTGATGCTGCTGCCAGT
GTGGGGCTTGAGCAAGCCATGTTGACTGGGTTAGCCAAAACCACCCTCGTTTGCCGTGGCCCTAAGCCAACCGCCGTGTT
ACGCCGTTATGAATTACGCCCAAGCATCAGCGCTGCCTCGCCCTACACCATCAACGATCTGATCAACAGCCTTGATCAAG
TTGAGTTGGCCGAACGTGGCGTTGGCTTGTTGCACTATGGCGAACGCGATCGCAAATTAGCCGATTATTGCCGCGAACGC
GGGGCGGTGCTCCACGAACATAGTGTGTATGAATGGCAATTGCCTGCTGATATCAGCCCACTGCTCGCGCTGATCGAACA
AGCAATTGCTGGTCAGGTCGATATTTTTACCTTTACCAGCCAAATTCAAGTGCGCCATTTGTTGCACGTTGCCGAGCAAC
AAGGCCAAGCCCAAGCATTAATTGCGGCCATGCAACAGGCCTTGGTCGCAGCGGTCGGCCCATCGTGCGCCCAAGCATTA
ATCAATCTTGGCATTCAACAGGTAATTATGCCTGAACAGCCGTTTATGGGCCAGATGGTGCAACGAATTCTCGACCATGT
GAGCGTCAATATTTAG

Upstream 100 bases:

>100_bases
CATGTGCGGTACAATTACGGCCAATCGTCGAAGGTATCAATATCAAATTTGGCGAAGCCGCCTCAGTTCCAGCAATGGCC
GCTGGCAAACGGAGCAGCCA

Downstream 100 bases:

>100_bases
TGTCCCTCACTCTTGTCCTTACAAGGGGTGGGTTTTAATCGTTTTCTATTGTGAACCACCAATTCCGTGGTTTATCGGTA
GATGCCTGTTCACCACTCCA

Product: uroporphyrinogen III synthase HEM4

Products: coproporphyrinogen; CO2

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MSSLHGQRIAILEARRASELANLLSRHGANPIHAPALREVSVDAAPVAQAVLQELEAGQIDLLILLTGVGTQQLIDAAAS
VGLEQAMLTGLAKTTLVCRGPKPTAVLRRYELRPSISAASPYTINDLINSLDQVELAERGVGLLHYGERDRKLADYCRER
GAVLHEHSVYEWQLPADISPLLALIEQAIAGQVDIFTFTSQIQVRHLLHVAEQQGQAQALIAAMQQALVAAVGPSCAQAL
INLGIQQVIMPEQPFMGQMVQRILDHVSVNI

Sequences:

>Translated_271_residues
MSSLHGQRIAILEARRASELANLLSRHGANPIHAPALREVSVDAAPVAQAVLQELEAGQIDLLILLTGVGTQQLIDAAAS
VGLEQAMLTGLAKTTLVCRGPKPTAVLRRYELRPSISAASPYTINDLINSLDQVELAERGVGLLHYGERDRKLADYCRER
GAVLHEHSVYEWQLPADISPLLALIEQAIAGQVDIFTFTSQIQVRHLLHVAEQQGQAQALIAAMQQALVAAVGPSCAQAL
INLGIQQVIMPEQPFMGQMVQRILDHVSVNI
>Mature_270_residues
SSLHGQRIAILEARRASELANLLSRHGANPIHAPALREVSVDAAPVAQAVLQELEAGQIDLLILLTGVGTQQLIDAAASV
GLEQAMLTGLAKTTLVCRGPKPTAVLRRYELRPSISAASPYTINDLINSLDQVELAERGVGLLHYGERDRKLADYCRERG
AVLHEHSVYEWQLPADISPLLALIEQAIAGQVDIFTFTSQIQVRHLLHVAEQQGQAQALIAAMQQALVAAVGPSCAQALI
NLGIQQVIMPEQPFMGQMVQRILDHVSVNI

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003754 [H]

Pfam domain/function: PF02602 HEM4 [H]

EC number: 4.1.1.37; 4.2.1.75

Molecular weight: Translated: 29294; Mature: 29163

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLHGQRIAILEARRASELANLLSRHGANPIHAPALREVSVDAAPVAQAVLQELEAGQI
CCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCE
DLLILLTGVGTQQLIDAAASVGLEQAMLTGLAKTTLVCRGPKPTAVLRRYELRPSISAAS
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHCCCCCCCCC
PYTINDLINSLDQVELAERGVGLLHYGERDRKLADYCRERGAVLHEHSVYEWQLPADISP
CEEHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHCCCEEECCCCEEEECCCCHHH
LLALIEQAIAGQVDIFTFTSQIQVRHLLHVAEQQGQAQALIAAMQQALVAAVGPSCAQAL
HHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHH
INLGIQQVIMPEQPFMGQMVQRILDHVSVNI
HHHCHHHHHCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSLHGQRIAILEARRASELANLLSRHGANPIHAPALREVSVDAAPVAQAVLQELEAGQI
CCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCE
DLLILLTGVGTQQLIDAAASVGLEQAMLTGLAKTTLVCRGPKPTAVLRRYELRPSISAAS
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHCCCCCCCCC
PYTINDLINSLDQVELAERGVGLLHYGERDRKLADYCRERGAVLHEHSVYEWQLPADISP
CEEHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHCCCEEECCCCEEEECCCCHHH
LLALIEQAIAGQVDIFTFTSQIQVRHLLHVAEQQGQAQALIAAMQQALVAAVGPSCAQAL
HHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHH
INLGIQQVIMPEQPFMGQMVQRILDHVSVNI
HHHCHHHHHCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: uroporphyrinogen III

Specific reaction: uroporphyrinogen III = coproporphyrinogen + 4 CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]