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The map label for this gene is dnaJ [H]

Identifier: 159898740

GI number: 159898740

Start: 2818503

End: 2819486

Strand: Reverse

Name: dnaJ [H]

Synonym: Haur_2219

Alternate gene names: 159898740

Gene position: 2819486-2818503 (Counterclockwise)

Preceding gene: 159898741

Following gene: 159898739

Centisome position: 44.43

GC content: 51.63

Gene sequence:

>984_bases
ATGAAAACGCACTACGAGGTGCTAGGGGTTGCCAGCAACGCCGATGCCGCCACAATCGACGCAGCATTTCGGCGTTTGGC
CCGCCAATATCACCCAGATATTAATAAAGCTCCCGATGCCACGGCCTTGATGCAGGCCTTGAATATTGCCTATGGTGTAT
TGAAAGATGCCCAAAAGCGCCAAGCCTATGATCGTGAATTGAGCGGCCAGCGTGATCAACCGCAGCCACGCCAGCAATCG
AGCGGCAATGCGATCAACGATTTGTTTGCCGTGGCTTGGCATGCAGCGCATCCAGCAGTTTATTTGTACGAAAATCATAC
AGTTGAGATTGCAGGCAATAGTTTTCGCTTTGATTTTGCTTATCCTGCGCAAAAAATTGGGATTATTTGCCAAGCCTCAG
CCAGTTCGCAAACAACTTGGGCCGATTGGCAGGTGATTCAATTAACTGCCCAGCAAATTATGAGTAATCCGATGGCGGCA
GCCGAAGCGGCCTACCAAGCTTTAGCCGAAACCGCCTATGCAAGTACAAATCCAACCGAGTATGCCGCTGCCCAAGCCGA
GTTGCGCTGGGCCGAAGAATGGCTTGAAAAATATGATCAAGCACAGTCGAATGGTGAAGATTTTGAGGAGCAGATTCGCA
CAAGTCTTGCACCACAATACAAACCGATGCTTGATTTGGCGCTGGTTGGTGGGGTTGGCGCGATTGTCGCCACGACCGTG
GTTGGGGCAATCATCAAGTTGGCCTTGGCTGGGTTTGTGGCGATGGTAGCGGGTGCATTGCTGGCGGTGCGCTTTGTTCC
AAGCCTGATTCAAGCATGGTCGGATGACCTACGGATCAAAGTTTTTGGGGCTAGTGCTGGAATTTGTTTGCTGCTGTTGC
TGGTGATTCATGGCGGCAGTGCCATTGGCTTGCTGGTTGGGGCTAGCTTGATTGGTGGCTTAGTGGGCTATGTCTATGCC
ATGCGCCAACAAGCCAAGGTTTAG

Upstream 100 bases:

>100_bases
CCATCAAGCCAAATTGAATCATGATCTTTGGGAAAATCATGCGATCTATCGCCAACAATTACGTGGTTTTTTTGGTTTAG
CAGCGAGTGAATAATTCTTT

Downstream 100 bases:

>100_bases
AGGTGCAGCATGCAGATGCTACGTTGTGTCCCCCATCAACGAGTGCTTTTAGCAACCACGCCAGCTCAACCTAGCTGGCG
TTTAAAACAGACCATCATTG

Product: heat shock protein DnaJ domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MKTHYEVLGVASNADAATIDAAFRRLARQYHPDINKAPDATALMQALNIAYGVLKDAQKRQAYDRELSGQRDQPQPRQQS
SGNAINDLFAVAWHAAHPAVYLYENHTVEIAGNSFRFDFAYPAQKIGIICQASASSQTTWADWQVIQLTAQQIMSNPMAA
AEAAYQALAETAYASTNPTEYAAAQAELRWAEEWLEKYDQAQSNGEDFEEQIRTSLAPQYKPMLDLALVGGVGAIVATTV
VGAIIKLALAGFVAMVAGALLAVRFVPSLIQAWSDDLRIKVFGASAGICLLLLLVIHGGSAIGLLVGASLIGGLVGYVYA
MRQQAKV

Sequences:

>Translated_327_residues
MKTHYEVLGVASNADAATIDAAFRRLARQYHPDINKAPDATALMQALNIAYGVLKDAQKRQAYDRELSGQRDQPQPRQQS
SGNAINDLFAVAWHAAHPAVYLYENHTVEIAGNSFRFDFAYPAQKIGIICQASASSQTTWADWQVIQLTAQQIMSNPMAA
AEAAYQALAETAYASTNPTEYAAAQAELRWAEEWLEKYDQAQSNGEDFEEQIRTSLAPQYKPMLDLALVGGVGAIVATTV
VGAIIKLALAGFVAMVAGALLAVRFVPSLIQAWSDDLRIKVFGASAGICLLLLLVIHGGSAIGLLVGASLIGGLVGYVYA
MRQQAKV
>Mature_327_residues
MKTHYEVLGVASNADAATIDAAFRRLARQYHPDINKAPDATALMQALNIAYGVLKDAQKRQAYDRELSGQRDQPQPRQQS
SGNAINDLFAVAWHAAHPAVYLYENHTVEIAGNSFRFDFAYPAQKIGIICQASASSQTTWADWQVIQLTAQQIMSNPMAA
AEAAYQALAETAYASTNPTEYAAAQAELRWAEEWLEKYDQAQSNGEDFEEQIRTSLAPQYKPMLDLALVGGVGAIVATTV
VGAIIKLALAGFVAMVAGALLAVRFVPSLIQAWSDDLRIKVFGASAGICLLLLLVIHGGSAIGLLVGASLIGGLVGYVYA
MRQQAKV

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI9558755, Length=95, Percent_Identity=38.9473684210526, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1787235, Length=98, Percent_Identity=38.7755102040816, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21358273, Length=63, Percent_Identity=52.3809523809524, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 35217; Mature: 35217

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTHYEVLGVASNADAATIDAAFRRLARQYHPDINKAPDATALMQALNIAYGVLKDAQKR
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QAYDRELSGQRDQPQPRQQSSGNAINDLFAVAWHAAHPAVYLYENHTVEIAGNSFRFDFA
HHHHHHHCCCCCCCCCCHHCCCCHHHHHHHHHHHHCCCEEEEEECCEEEEECCEEEEEEC
YPAQKIGIICQASASSQTTWADWQVIQLTAQQIMSNPMAAAEAAYQALAETAYASTNPTE
CCHHHHCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHH
YAAAQAELRWAEEWLEKYDQAQSNGEDFEEQIRTSLAPQYKPMLDLALVGGVGAIVATTV
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VGAIIKLALAGFVAMVAGALLAVRFVPSLIQAWSDDLRIKVFGASAGICLLLLLVIHGGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCC
AIGLLVGASLIGGLVGYVYAMRQQAKV
HHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTHYEVLGVASNADAATIDAAFRRLARQYHPDINKAPDATALMQALNIAYGVLKDAQKR
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QAYDRELSGQRDQPQPRQQSSGNAINDLFAVAWHAAHPAVYLYENHTVEIAGNSFRFDFA
HHHHHHHCCCCCCCCCCHHCCCCHHHHHHHHHHHHCCCEEEEEECCEEEEECCEEEEEEC
YPAQKIGIICQASASSQTTWADWQVIQLTAQQIMSNPMAAAEAAYQALAETAYASTNPTE
CCHHHHCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHH
YAAAQAELRWAEEWLEKYDQAQSNGEDFEEQIRTSLAPQYKPMLDLALVGGVGAIVATTV
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VGAIIKLALAGFVAMVAGALLAVRFVPSLIQAWSDDLRIKVFGASAGICLLLLLVIHGGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCC
AIGLLVGASLIGGLVGYVYAMRQQAKV
HHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA