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The map label for this gene is yesM [H]

Identifier: 159898643

GI number: 159898643

Start: 2665038

End: 2666588

Strand: Reverse

Name: yesM [H]

Synonym: Haur_2122

Alternate gene names: 159898643

Gene position: 2666588-2665038 (Counterclockwise)

Preceding gene: 159898644

Following gene: 159898642

Centisome position: 42.02

GC content: 50.48

Gene sequence:

>1551_bases
ATGGATGAAAAGCTGCCAAATCATGAGCCGATGGGAGTTGTGCTGGCTAGGTGGGCGGCTGCCCCACGGCTACGCCTACG
ATTGTCTATCCGCGACAAAATCCTGTTGGCATTGTTGATGGTGGTCATCTTGATGAGCGTGCCATATATCTTTCTGATTG
TCCCCGGGCTAGAATACAAGACCCAATATGACGTGCTGATTCAAAATATTACTACCGCCAACAGCATCAACGGCTATATC
AAGCCATCGATCGATGCCGAACTGTGGGAGATTATTGCCGGCAAGAAACCGTTTGCCCAAGGTACGCAGTATGCAATCTT
GAACGATATCGACCATCGCATTGAGCTAATGATCGATAACTCTAGCTCTCAAAAGGGTCGCGTTAAACTTGGTATTATTC
AGCACACGCTGCAAACGCTCCGCAGGTTGATCGATAAGGTTGGTATTCAGATTGCCCAAGCTAAAACCTTTGCCGAAAAT
TTGGTGCTGATGGAGGAAATTCGTAGTATTACCCAGTTGATTGAGGGCAACGTACAAGCCTATGCCTTGTTTGAAGTTAA
TCGAACCCAACAGCAATATCAGGCAATGCAAAGCGACCTGACACGCTGGGCGATCGGTGGTATAGGCGTGATCATGGCTT
CGATCCTCTTCTCGATCGTTGCTGCTTGGCGGATCTCAAAAGGTATCTATATTCCGATTAAGAAGCTGCACGATGTGACT
ACTACGATTGCCCGCCAAGATCTCGAAGGGCTGGTGATGGCTGATAACGCCGACGAGATCACAGAATTAGGCTTGAGCTT
TAATATTATGGTTGGTAAGATCAAAGAATTGCTTGATGCTAAGCTCGAAGAACACGAGAACCTCAAAAAGGCTGAGCTAC
GGGTGCTCCAAGCACAAATCAACCCCCATTTCCTCTACAACACCCTTGATGCAATTATCTGGATGGCCGAAGCCAAGCGC
ACAGCACAGATTATCGATCTGGTTTCGGCGTTGTCGCGCTTCTTCCGAATTACGCTCAGTAAAGGCCGAGATTGGATCAG
CGTTCCTGACGAGATCGCGCATATCGAAAGCTATCTGGCGATCCAGAAAATTCGCTACCGCGATATCCTCGATTACCAGA
TCGATATTCCTGAGGACACCCAGAGCACCGAGATGCTCAAGCTGACGCTCCAACCGTTGGTGGAGAATGCACTGTATCAC
GGGATCAAGAATAAGCGGAGCGGTGGAACTATTGTGGTGCGTGGCCGCTGGCTCGATGGTGATCGACTGCGAATCGAAGT
CGAAGACAATGGGATTGGCATGACCCAAGAGCGGCTGCAGCAGGTGCGGACGTTGCTGGAGGCGGGGAACCTGTGGGTTA
CAGGCGTAATGCCCATCGTCGAGGATGGCTACGGGATCAGTAATGTTAACCAGCGTATCAAGCTCTACTATGGCTCCGAC
TATGGATTGTCGATCGAAAGCGAACATGGGCGTGGCACGTGTGTGGCGCTGATCATCCCGCGCTACCGTGGCATTACCAC
CCAACCGCCACTGGCGCTTGCTGCTCGCTAA

Upstream 100 bases:

>100_bases
CTACTCGGTGTTTCGCAAGGTTGTCGGTCAGCCACCCAACGAGTTCCGTCAGCGCTTCTAGCACCAACTGTCGCCTCCAG
ATTACCAGAGGGTTTGTATC

Downstream 100 bases:

>100_bases
CAGGCTGATCGTAAAAAATCGAACACTATGCTAAAAAACTCGACACGCCGATCTCTAAAAAATCATTAAAATAGCGGATA
TTCTGCGTAGAAATTACGAT

Product: histidine kinase internal region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MDEKLPNHEPMGVVLARWAAAPRLRLRLSIRDKILLALLMVVILMSVPYIFLIVPGLEYKTQYDVLIQNITTANSINGYI
KPSIDAELWEIIAGKKPFAQGTQYAILNDIDHRIELMIDNSSSQKGRVKLGIIQHTLQTLRRLIDKVGIQIAQAKTFAEN
LVLMEEIRSITQLIEGNVQAYALFEVNRTQQQYQAMQSDLTRWAIGGIGVIMASILFSIVAAWRISKGIYIPIKKLHDVT
TTIARQDLEGLVMADNADEITELGLSFNIMVGKIKELLDAKLEEHENLKKAELRVLQAQINPHFLYNTLDAIIWMAEAKR
TAQIIDLVSALSRFFRITLSKGRDWISVPDEIAHIESYLAIQKIRYRDILDYQIDIPEDTQSTEMLKLTLQPLVENALYH
GIKNKRSGGTIVVRGRWLDGDRLRIEVEDNGIGMTQERLQQVRTLLEAGNLWVTGVMPIVEDGYGISNVNQRIKLYYGSD
YGLSIESEHGRGTCVALIIPRYRGITTQPPLALAAR

Sequences:

>Translated_516_residues
MDEKLPNHEPMGVVLARWAAAPRLRLRLSIRDKILLALLMVVILMSVPYIFLIVPGLEYKTQYDVLIQNITTANSINGYI
KPSIDAELWEIIAGKKPFAQGTQYAILNDIDHRIELMIDNSSSQKGRVKLGIIQHTLQTLRRLIDKVGIQIAQAKTFAEN
LVLMEEIRSITQLIEGNVQAYALFEVNRTQQQYQAMQSDLTRWAIGGIGVIMASILFSIVAAWRISKGIYIPIKKLHDVT
TTIARQDLEGLVMADNADEITELGLSFNIMVGKIKELLDAKLEEHENLKKAELRVLQAQINPHFLYNTLDAIIWMAEAKR
TAQIIDLVSALSRFFRITLSKGRDWISVPDEIAHIESYLAIQKIRYRDILDYQIDIPEDTQSTEMLKLTLQPLVENALYH
GIKNKRSGGTIVVRGRWLDGDRLRIEVEDNGIGMTQERLQQVRTLLEAGNLWVTGVMPIVEDGYGISNVNQRIKLYYGSD
YGLSIESEHGRGTCVALIIPRYRGITTQPPLALAAR
>Mature_516_residues
MDEKLPNHEPMGVVLARWAAAPRLRLRLSIRDKILLALLMVVILMSVPYIFLIVPGLEYKTQYDVLIQNITTANSINGYI
KPSIDAELWEIIAGKKPFAQGTQYAILNDIDHRIELMIDNSSSQKGRVKLGIIQHTLQTLRRLIDKVGIQIAQAKTFAEN
LVLMEEIRSITQLIEGNVQAYALFEVNRTQQQYQAMQSDLTRWAIGGIGVIMASILFSIVAAWRISKGIYIPIKKLHDVT
TTIARQDLEGLVMADNADEITELGLSFNIMVGKIKELLDAKLEEHENLKKAELRVLQAQINPHFLYNTLDAIIWMAEAKR
TAQIIDLVSALSRFFRITLSKGRDWISVPDEIAHIESYLAIQKIRYRDILDYQIDIPEDTQSTEMLKLTLQPLVENALYH
GIKNKRSGGTIVVRGRWLDGDRLRIEVEDNGIGMTQERLQQVRTLLEAGNLWVTGVMPIVEDGYGISNVNQRIKLYYGSD
YGLSIESEHGRGTCVALIIPRYRGITTQPPLALAAR

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=243, Percent_Identity=31.2757201646091, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1788723, Length=223, Percent_Identity=35.4260089686099, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58348; Mature: 58348

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEKLPNHEPMGVVLARWAAAPRLRLRLSIRDKILLALLMVVILMSVPYIFLIVPGLEYK
CCCCCCCCCCCHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
TQYDVLIQNITTANSINGYIKPSIDAELWEIIAGKKPFAQGTQYAILNDIDHRIELMIDN
CHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEEEEC
SSSQKGRVKLGIIQHTLQTLRRLIDKVGIQIAQAKTFAENLVLMEEIRSITQLIEGNVQA
CCCCCCCEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
YALFEVNRTQQQYQAMQSDLTRWAIGGIGVIMASILFSIVAAWRISKGIYIPIKKLHDVT
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHH
TTIARQDLEGLVMADNADEITELGLSFNIMVGKIKELLDAKLEEHENLKKAELRVLQAQI
HHHHHHCCCCEEEECCHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
NPHFLYNTLDAIIWMAEAKRTAQIIDLVSALSRFFRITLSKGRDWISVPDEIAHIESYLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
IQKIRYRDILDYQIDIPEDTQSTEMLKLTLQPLVENALYHGIKNKRSGGTIVVRGRWLDG
HHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCC
DRLRIEVEDNGIGMTQERLQQVRTLLEAGNLWVTGVMPIVEDGYGISNVNQRIKLYYGSD
CEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECHHHHCCCCCCCCCCCEEEEEECCC
YGLSIESEHGRGTCVALIIPRYRGITTQPPLALAAR
CCEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDEKLPNHEPMGVVLARWAAAPRLRLRLSIRDKILLALLMVVILMSVPYIFLIVPGLEYK
CCCCCCCCCCCHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
TQYDVLIQNITTANSINGYIKPSIDAELWEIIAGKKPFAQGTQYAILNDIDHRIELMIDN
CHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEEEEC
SSSQKGRVKLGIIQHTLQTLRRLIDKVGIQIAQAKTFAENLVLMEEIRSITQLIEGNVQA
CCCCCCCEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
YALFEVNRTQQQYQAMQSDLTRWAIGGIGVIMASILFSIVAAWRISKGIYIPIKKLHDVT
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHH
TTIARQDLEGLVMADNADEITELGLSFNIMVGKIKELLDAKLEEHENLKKAELRVLQAQI
HHHHHHCCCCEEEECCHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
NPHFLYNTLDAIIWMAEAKRTAQIIDLVSALSRFFRITLSKGRDWISVPDEIAHIESYLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
IQKIRYRDILDYQIDIPEDTQSTEMLKLTLQPLVENALYHGIKNKRSGGTIVVRGRWLDG
HHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCC
DRLRIEVEDNGIGMTQERLQQVRTLLEAGNLWVTGVMPIVEDGYGISNVNQRIKLYYGSD
CEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECHHHHCCCCCCCCCCCEEEEEECCC
YGLSIESEHGRGTCVALIIPRYRGITTQPPLALAAR
CCEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]