Click here to switch to the map view.

The map label for this gene is lgrC [H]

Identifier: 159898628

GI number: 159898628

Start: 2639277

End: 2640791

Strand: Reverse

Name: lgrC [H]

Synonym: Haur_2107

Alternate gene names: 159898628

Gene position: 2640791-2639277 (Counterclockwise)

Preceding gene: 159898629

Following gene: 159898627

Centisome position: 41.61

GC content: 52.28

Gene sequence:

>1515_bases
ATGGATGCTCTCCAGCAACGCTTGGCGCAGCTTTCGCCCGAAAAACGCGCCTTGCTTGAACAATTACGCTTGCAACGCCA
AGCAACGCCAGCGATTACGCCGCGTGATCCTGCGCAAATGGTGCCGTTATCGTTGGCACAGCAACGGCTTTGGCTGGTTG
AGCAAATGCGGCCAGGCCAGGCTACCTACATCATGCCCTGTTTGCTGATGATCAACGGTTCGTTGGATCGTGCTGCTTTG
GCGACGAGCCTGAGTTGGTTGCTCCAACGCCATGAAGTGCTACGCACCAGCATTCAGCCTGACAACCAAGGTGCATATCA
ACAGATTCACGAGCCTTGGCAGGTAGAATTGGGGTTGGTTGAGCTTGATCAAACCCAGCTTGAAACTCAGTTACGCCACT
ATGCCCGACAACCATTTGATTTGCAGCACGCGCCGTTATGGCGTGCCGCGTTGTGGCGCTGTGCTCCAGAGCAGCATGTT
TTAGGGTTGATGCTGCATCACATTATTGCTGATGGTTGGTCGTTAGGTGTGTTGATGCACGATTTGGCGCTGGCCTATGC
GCATTTTGCCACAGGCGCAGCGTTAAACCTTGCTCCGCTGGCAATTCACTATGGCGATTATGCCTGTTGGCAAGCCCAAC
AGCCAGCAACGCTGACCCAAAGCAGCCGTGATTTTTGGCTGAAGCTCTTGCACGATGTACCAACTCTGGCCTTGCCAACC
GACTATCCTCGACCTGCTGTTCAATCGTTTCAGGGGGCACAAATCGCTTGGCGCTTGCCGAGGGAGTTGGTCGAACAACT
CAAGCAACTTAGTCAAAGCCAGAGCGCAACCTTATTTATGAGTTTGCTAACGGCATTTTATTGGCTTTTACACTGGCTAA
GTGAGCAAACTGATTTAGTGGTTGGCACTGATGTTGCAGGGCGACAACAGCCTGAGACCCATCAATTGATCGGCTTTTTC
ATTAATCAATTGGTGCTACGTCAACAAGTTCAGCCGCATCAATCGTTCCAAGCAAGCCTACAACAAACCCGCCAGCTCAC
ATTAGCGGCCTTTGACCACCAACATGTGCCATTCGATCAAGTTGTCGAATGGTTGAACGTTGCCCACGACCCCAGCCGCA
CGCCGTTGTTTCAGGTCAAATTTGTGTTGCAAAACACGCCCTTGCCCAACTTACAACTAGCAGGTGTGCAGCTTGAACGC
ATGGATCTTGATCCGCACACTGCCAAATTTGATTTGCTGATCAATCTTTGGGAAGAGCATGCAGGCTTAGCGGGAACCCT
TGATTACAACACCGATATTTTCGCAGCGCAGCGCATGCAGCAATTACTTGAGCGCTATCAGCTGGTGCTTCAGTTGATCG
TGCTTGAACCGACGATCACGCTTGCGGTTGCGGTGCAGCGTTGCCAAAGCCACGAGCGCGAGCTTCAACAGCAACGGCTG
GAGCAACGCAAGGCAGCAAATCGTTCCAAATTAATCCTGAATCGGCGACGGTCGAGCACCGAGCCAACCCAATAG

Upstream 100 bases:

>100_bases
TCAAACTGCTGAACTAGCGGCCCTGCTTGATGAGCTTGATCAATTGAGTGATGACGAGGCGCGTGCCCGTTTATTGGCTG
ATTTTTAGCGAGGCTCACCC

Downstream 100 bases:

>100_bases
AAGGATGATTGTATGCAGCAACATGAAGTTGAGCATTTTCGGCTATCGCCGCAACAAACCCATACATGGTTGGTTCAACC
ACAAAGCCAGCAACCCTTGG

Product: condensation domain-containing protein

Products: NA

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MDALQQRLAQLSPEKRALLEQLRLQRQATPAITPRDPAQMVPLSLAQQRLWLVEQMRPGQATYIMPCLLMINGSLDRAAL
ATSLSWLLQRHEVLRTSIQPDNQGAYQQIHEPWQVELGLVELDQTQLETQLRHYARQPFDLQHAPLWRAALWRCAPEQHV
LGLMLHHIIADGWSLGVLMHDLALAYAHFATGAALNLAPLAIHYGDYACWQAQQPATLTQSSRDFWLKLLHDVPTLALPT
DYPRPAVQSFQGAQIAWRLPRELVEQLKQLSQSQSATLFMSLLTAFYWLLHWLSEQTDLVVGTDVAGRQQPETHQLIGFF
INQLVLRQQVQPHQSFQASLQQTRQLTLAAFDHQHVPFDQVVEWLNVAHDPSRTPLFQVKFVLQNTPLPNLQLAGVQLER
MDLDPHTAKFDLLINLWEEHAGLAGTLDYNTDIFAAQRMQQLLERYQLVLQLIVLEPTITLAVAVQRCQSHERELQQQRL
EQRKAANRSKLILNRRRSSTEPTQ

Sequences:

>Translated_504_residues
MDALQQRLAQLSPEKRALLEQLRLQRQATPAITPRDPAQMVPLSLAQQRLWLVEQMRPGQATYIMPCLLMINGSLDRAAL
ATSLSWLLQRHEVLRTSIQPDNQGAYQQIHEPWQVELGLVELDQTQLETQLRHYARQPFDLQHAPLWRAALWRCAPEQHV
LGLMLHHIIADGWSLGVLMHDLALAYAHFATGAALNLAPLAIHYGDYACWQAQQPATLTQSSRDFWLKLLHDVPTLALPT
DYPRPAVQSFQGAQIAWRLPRELVEQLKQLSQSQSATLFMSLLTAFYWLLHWLSEQTDLVVGTDVAGRQQPETHQLIGFF
INQLVLRQQVQPHQSFQASLQQTRQLTLAAFDHQHVPFDQVVEWLNVAHDPSRTPLFQVKFVLQNTPLPNLQLAGVQLER
MDLDPHTAKFDLLINLWEEHAGLAGTLDYNTDIFAAQRMQQLLERYQLVLQLIVLEPTITLAVAVQRCQSHERELQQQRL
EQRKAANRSKLILNRRRSSTEPTQ
>Mature_504_residues
MDALQQRLAQLSPEKRALLEQLRLQRQATPAITPRDPAQMVPLSLAQQRLWLVEQMRPGQATYIMPCLLMINGSLDRAAL
ATSLSWLLQRHEVLRTSIQPDNQGAYQQIHEPWQVELGLVELDQTQLETQLRHYARQPFDLQHAPLWRAALWRCAPEQHV
LGLMLHHIIADGWSLGVLMHDLALAYAHFATGAALNLAPLAIHYGDYACWQAQQPATLTQSSRDFWLKLLHDVPTLALPT
DYPRPAVQSFQGAQIAWRLPRELVEQLKQLSQSQSATLFMSLLTAFYWLLHWLSEQTDLVVGTDVAGRQQPETHQLIGFF
INQLVLRQQVQPHQSFQASLQQTRQLTLAAFDHQHVPFDQVVEWLNVAHDPSRTPLFQVKFVLQNTPLPNLQLAGVQLER
MDLDPHTAKFDLLINLWEEHAGLAGTLDYNTDIFAAQRMQQLLERYQLVLQLIVLEPTITLAVAVQRCQSHERELQQQRL
EQRKAANRSKLILNRRRSSTEPTQ

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: NA

Molecular weight: Translated: 57806; Mature: 57806

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALQQRLAQLSPEKRALLEQLRLQRQATPAITPRDPAQMVPLSLAQQRLWLVEQMRPGQ
CCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
ATYIMPCLLMINGSLDRAALATSLSWLLQRHEVLRTSIQPDNQGAYQQIHEPWQVELGLV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCEEEEEEE
ELDQTQLETQLRHYARQPFDLQHAPLWRAALWRCAPEQHVLGLMLHHIIADGWSLGVLMH
ECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHH
DLALAYAHFATGAALNLAPLAIHYGDYACWQAQQPATLTQSSRDFWLKLLHDVPTLALPT
HHHHHHHHHHCCCCCCHHHEEEECCCCHHCCCCCCCHHHCCHHHHHHHHHHCCCCCCCCC
DYPRPAVQSFQGAQIAWRLPRELVEQLKQLSQSQSATLFMSLLTAFYWLLHWLSEQTDLV
CCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VGTDVAGRQQPETHQLIGFFINQLVLRQQVQPHQSFQASLQQTRQLTLAAFDHQHVPFDQ
EECCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VVEWLNVAHDPSRTPLFQVKFVLQNTPLPNLQLAGVQLERMDLDPHTAKFDLLINLWEEH
HHHHHHHCCCCCCCCCEEEEEEECCCCCCCCEECCEEEEEECCCCCCHHHHHHHHHHHHH
AGLAGTLDYNTDIFAAQRMQQLLERYQLVLQLIVLEPTITLAVAVQRCQSHERELQQQRL
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
EQRKAANRSKLILNRRRSSTEPTQ
HHHHHCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MDALQQRLAQLSPEKRALLEQLRLQRQATPAITPRDPAQMVPLSLAQQRLWLVEQMRPGQ
CCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
ATYIMPCLLMINGSLDRAALATSLSWLLQRHEVLRTSIQPDNQGAYQQIHEPWQVELGLV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCEEEEEEE
ELDQTQLETQLRHYARQPFDLQHAPLWRAALWRCAPEQHVLGLMLHHIIADGWSLGVLMH
ECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHH
DLALAYAHFATGAALNLAPLAIHYGDYACWQAQQPATLTQSSRDFWLKLLHDVPTLALPT
HHHHHHHHHHCCCCCCHHHEEEECCCCHHCCCCCCCHHHCCHHHHHHHHHHCCCCCCCCC
DYPRPAVQSFQGAQIAWRLPRELVEQLKQLSQSQSATLFMSLLTAFYWLLHWLSEQTDLV
CCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VGTDVAGRQQPETHQLIGFFINQLVLRQQVQPHQSFQASLQQTRQLTLAAFDHQHVPFDQ
EECCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VVEWLNVAHDPSRTPLFQVKFVLQNTPLPNLQLAGVQLERMDLDPHTAKFDLLINLWEEH
HHHHHHHCCCCCCCCCEEEEEEECCCCCCCCEECCEEEEEECCCCCCHHHHHHHHHHHHH
AGLAGTLDYNTDIFAAQRMQQLLERYQLVLQLIVLEPTITLAVAVQRCQSHERELQQQRL
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
EQRKAANRSKLILNRRRSSTEPTQ
HHHHHCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA