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The map label for this gene is lgrC [H]

Identifier: 159898613

GI number: 159898613

Start: 2613140

End: 2618125

Strand: Reverse

Name: lgrC [H]

Synonym: Haur_2092

Alternate gene names: 159898613

Gene position: 2618125-2613140 (Counterclockwise)

Preceding gene: 159898614

Following gene: 159898612

Centisome position: 41.25

GC content: 51.22

Gene sequence:

>4986_bases
ATGCCAACTGTGTTAGAGCCAATAACGCCTGATGCGCTCAGCGAAACGTTGCGCCAGTATTTGCAAGCGTATCTGCCGGA
TTATATGCTGCCAGCGGCGTTTGTGCCGCTTGAACAGATTCCGCGCTTGCCGAATGGCAAAATTGACCGTGCGGCCTTGC
CAATGGTCGATTTTGCAGCCCAGCATGAGCAGCAAACCCAAACGGCCCCACGTAACCCGCTTGAGCAGCAGCTCGCGGCA
ATTTGGCAGCAAACCTTGCAAGTACCAAGCGTGGGCATTCACGATAACTTTTTTCAATTGGGCGGCGATTCAATTTTGAG
CATTCAGGTGATTGCTCGTGCTAATCGAGCTGGCATACGGCTGACTACGCGCCAATTGTTTGAGCAGCCAACGATTGCCC
AACTAGCAAGCTTGGCGCAAACCACAACAATAGATGTTGCTCATAGCGAATTGTCTGCTGGACAGATCGTTCCCCTAACA
CCAATTCAGCGCTGGTTGCTCGCTGATCCTACTGATCCCAGCCAGTTTAATCAGGCACTCTTTTTGCAATTTACTCAGGC
TATTGATTCGAATTTGGTGGCATCGGCGGTTGAGCACGTTGCACAGCTACATGTCAGTTTGCGTTTGCGCTATCGCCGTA
CTGCTGATGGTTGGCAACAATTTGTGGCTGCTGCTGATGCACCACTGGTTGAATTTGAGCAAATTAATGCTCAAAACCTC
AATCCAACGGAGCTGGCTGAGCTTTTCGAGGCTACAACTGAACGACTGCAACGGCCCTTTGATTTGGCGAAGGCTGCACT
GTGGCGAATTGCCTACATCGCCATGCCTGATGCTCAGCCCGCCCGCTTGCTGTTGGTCATGCATCACTTGGTGGTTGATG
GGGTTTCGTGGCGAATTATCATTCAAGATCTCGCCCATGCCTTGCAAAACCAGCCATTAACCAAACCAGCTGTCGGTTTT
GCCCAATGGGCTATTGCTTTAGAACGCTATGCCCACCGCACCGAATTGCAGCAGCAACGTGCATATTGGCTAGCCCAAAC
CAGCACTGATCCCTTGCCAGTCGATGATATAACTGGACATAATGATTATGCGAGTGTTGCGACAATCACTAAGCAATTGA
GCCAGGCCCATACCACAGCCTTAATTCATCAAGCATCCCAGGCCTATCAAACCCAGATCAACGAACTATTGCTAGCAGCC
TTGACCCAAACCATCACCGCTTGGAGCGGCCACGCCGATGTGGTGCTGCAACTCGAAGGCCATGGTCGCGAGGAGCTGGA
TCAGCCGCTCGATCTTTCGCAAACTGTTGGGTGGTTTACTACGCTGTTTCCAATAAAGTTAAGTCTGCCACAAAAACTAG
GCTCCAAAAACCTGATCAAACAGATTAAAGAACAGATACGTGCAGTTCCCCAACGCGGGTTTGGCTATGGCTTGTTACGC
TCAGCTGATGCGGCGTTGCAAGCTATGCCAACCCCAGCGATCAGCTTTAACTATTTTGGTCAACTTGATCAAACGCTCCA
GTCAAGCAAATTATTCAGTGCTGCGCCCGAATCGACCGGAAGCGCCGTGTTGCCGCAGCGGCGGCGTGAACAACTGCTAG
CGATCAACTGCCAAGTTTTGGCGGGCCAATTACAGATCGAATGGTCGTATAGCCAACATCTGCATTCAGCAGCAACAATC
GAGCGCTTGGCTGAAGCATATTGTGCTGATTTAGTTGGGTTGATTGAGCATTGTTGTCAACAAACCCAACCAAGCTTTAC
GCCTGCCGATTTTCCTTTGGCGCAAATTACCCAAGCCCAACTTGACCAGATTGAGCAAATATATCCGCCGTTTGAGCAAT
TGTACCCTCTTTCATCGCTGCAACAGGGCATTTTGTTCCATCGCTTGTATGCGCCGGACGCTGGTGATTATATTACCCAA
ATGCAGTTTGAAATCACGGGTCAGCTCAATCATGCGGCATTTAGTGCTGCTTGGAATCGAACAATTGGCCATTATAGAAT
GCTGCGAACCGCGTTTGTTTGGCAAGATTTAGCTGAGCCACTGCAATTGGTGCTGCGCCAAGCTGTAATCACGATCGATT
TTCAACAGTTACCCATGAATAGCCTTGAACAAGAACAGGTGCTTGAAGCCTATTTGCAGGCTGATCGCACACGCGGCTTT
GAGCCAACCCAAGCGCCATTGATGCGTGTTGCTTTGTTCGAGCGTGCACCGCAACGCTATTGCTGTATCTGGACGAATCA
TCATTTGATCATCGATGGCTGGAGCTTACCGCTGATTCTTGATAGCTTGTTTCGCTATTATCAGGCTGAAATCAATCAGC
AACCACTGGAGCTTGCCCCAGAAATTCCTTATCAACGCTATATTCAATGGCTGGCTCAACATAATGATCAGCAAGCTACA
GCATTTTGGCGTGAATTATTGCGCGGTTTTACTGCTCCAACAAGCTTGGCGCTTGAACGGTTTGGCTCGACCCACGCTGA
ACGACACTATAGTGCGAGTTGGCTCCAGCTTGATTCTGCTATAACTCAGCAGCTTCAACAGTTTGCCCGCGATCATGGCC
TAACCGTGAATAGCCTGTTGCAGGCGGCGTGGGCCTTGGTTTTATCACGCTACAGTCATCAAACTGATATCGTGTTTGGT
ACAACGACGGCTGGCCGCCCAACCGATTTGGCCGGAGTTGAGCAGATTGTCGGGATGTTCGTGAATACGCTGCCCACGAG
AGTTAAGTGGGATTTGCAGCAGCCAGTGTTGGATTGGCTACAAGCCTTGCAGGCTCAAGAGAGTGCTGTGCGCAGTTACG
AGGCCAGTTCGCTCATTGAAATTCAGGCATGCAGCGAGTTGCCACGCAATAGCCCGCTGTTTGAAAGTATCTTGGTCTTT
GAAAACTATCCGGTGAGCAGTAGCGATTTAACTGGTTTGGGCGATTTAGAGTTACGTTTGGTTCCTTCGCGCGAGCAAAC
CAACTATCCTTTGACCTTAGTTGCTGTGCCAGGTGATGGGTTGGCCTTCAAGTTGATGTATCAACAAGGCTACATCGACC
AACTTACTAGCCAGCGCATGCTCGATTATCTCCAACAAGGCTTAGCCGCAATGCTAGCGCAGCCCAAGGCAAGGCTTGGC
CAGCTCAATATTGGGCATCCCAGCGAAATCCAAGCCTTGGCTGATTGGAACGCAACCGCAGCACCGCGCCAAACCAGCTC
GTTGCTTGAATGTTTTTACCAGCAGGTCGCAGCTCAGCCAACAAGCATCGCCGTCGCATGGCGTGAACAACGCTGGAGTT
ACTTCGATTTAGCACAGGCGAGCCAAGCAATTGCCGGCTATTTGCGCGATCAAGGGGTGCAACGCCAGCAAATTATCGGC
CTACGAGCTGAGCGCAACCCGCAGTTTGTCGCAGCGTTGTTGGCGATCTTGCAATTGGGCGCGGTGTATTTGCCGATTGA
TCCTCAGCATCCAGTGCAGCGCCAACAGCAACTTGCTCAGCATGTCGATTGGTTATTGACTGATGCCTTGGCTGAAGCGC
AGCCTCAGCAACTCGATTTGGCTCAGGCGTTGGGCTACGATCAACCTGCATCCGACTTTGTGCAACTCCATGATCGAGAT
TTAGCCTATGTGCTGTTTACCTCTGGCTCGACCGGCACACCCAAGGGCGTGATGATCGACCATGCAGGGATGCTGAATCA
TATTGACGTAATGATCGAGCGTTTGGCGCTAACCCAAACCGATTGTATTGCCCAAAGCGCTGCCCAATCGTTTGATATTT
CGGTTTGGCAGTTGCTGACAGCGCTCGTGGTTGGCGCTCGGATGCAGATCATTGATGATCAAACGATGCGCGATCCGCAG
GCCTTGTTAGCTAAATTGGCAGCGGCTAACGTTTCAATCTTCGAGCCAGTGCCCAGCCTGATTCAAGCCCTACTCGAAAC
GATTGCAAGCCTTGAGCAAACCCCAAGTTTGGCTGCTTTGCGTTGGGTGCTGCCAACTGGCGAACATTTGCCGCGTGAGC
TAGCCCAACAATGGTTTGCCCACTATCCTTATATTCCCTTGCTGAATGCCTATGGTCCGGCTGAATGCGCCGATGATGTG
ACGCTTTGGCCGATTGCCAGTGCTGTTGAGCTACCTCAAAACGCCATTCCAATTGGCCGACCAGTAGCCAATGTGCGGGC
TTATGTACTTGATGCCAGTTTGCGGCCAGTACCGATCGGCGTGGCAGGCGAGTTGTATATCGCTGGAATTGCGGTTGGTT
GGGGTTATTTGGCCGATCCCCAACGCACCGCTAGCCTGTTTTTGCCCGATCCTTGGGGCGAACCAGGGGCGCGAATGTAT
CGCACTGGCGATTTAGCGCGTTACAACCAAGCAGGTGTGTTGAGCTTCTTGGGGCGTAGCGATCAGCAAGTCAAAATTCG
CGGCTTCCGAATTGAGCTAGGCGAGATCGAAGCCTGTTTATTGCAGCATCCGGCGCTGCATTCGGTCGCAGTTGCTGTGG
TTGGCGTAGCTGAGCAAGCACGTTTGATCGCCTATCTGGTGGCGAAAGCTAAACCAGTCTCCGATCAATTACTACGTGAT
TTTGTCCAAGCGCGGTTGCCGCATTATCTGCAACCAAGTGGCTATTGTTGGTTGAGCCAATTGCCGCTCAATGCCAATGG
TAAATTAGACCGTCAGCGCTTGCCAATTCCCCAGCTGCAAACCGCTGAACGACTGATTATCGCTCCCCAAAACGCTGATC
AAGCCAAATTGGCCGAGCTTTGGGCGGCAATCTTGCAACGTGAGCAAGTTGGAATTAATCAGAATTTCTTTGAACTTGGC
GGTCATTCATTATTGGCAACCCGCTTGGTCAGCCAAATTCGCCAGTATTGGCAACTCGATTTGCCAATTCGGAGCGTATT
TGAGGCTCCGACAATCGAACAACTGGCTGATGTGCTTGATCTCCTACGCTGGGCGCAACAGGCTAATCAAGCTCCAGCTC
AAGCCCGCGAACAAGGAGCAATTTAA

Upstream 100 bases:

>100_bases
ATTTTTGGGCAAGGCCGCGCTAGAATAATCGCTTGGACGAGGTGTGTTTTTGTGGAAGCTTCCCCTCTAGGCTTCCCGCA
TAGATAGATTTCAGAAAGCG

Downstream 100 bases:

>100_bases
TCATGTGGCAATTGTTGACCCAATTACGGGCAGCCGATATTCGGATTTGGCTTGAAGGCGAGCGCTTATGCTACGATGCC
CCACCAGGCGTACTAAGTGA

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1661; Mature: 1660

Protein sequence:

>1661_residues
MPTVLEPITPDALSETLRQYLQAYLPDYMLPAAFVPLEQIPRLPNGKIDRAALPMVDFAAQHEQQTQTAPRNPLEQQLAA
IWQQTLQVPSVGIHDNFFQLGGDSILSIQVIARANRAGIRLTTRQLFEQPTIAQLASLAQTTTIDVAHSELSAGQIVPLT
PIQRWLLADPTDPSQFNQALFLQFTQAIDSNLVASAVEHVAQLHVSLRLRYRRTADGWQQFVAAADAPLVEFEQINAQNL
NPTELAELFEATTERLQRPFDLAKAALWRIAYIAMPDAQPARLLLVMHHLVVDGVSWRIIIQDLAHALQNQPLTKPAVGF
AQWAIALERYAHRTELQQQRAYWLAQTSTDPLPVDDITGHNDYASVATITKQLSQAHTTALIHQASQAYQTQINELLLAA
LTQTITAWSGHADVVLQLEGHGREELDQPLDLSQTVGWFTTLFPIKLSLPQKLGSKNLIKQIKEQIRAVPQRGFGYGLLR
SADAALQAMPTPAISFNYFGQLDQTLQSSKLFSAAPESTGSAVLPQRRREQLLAINCQVLAGQLQIEWSYSQHLHSAATI
ERLAEAYCADLVGLIEHCCQQTQPSFTPADFPLAQITQAQLDQIEQIYPPFEQLYPLSSLQQGILFHRLYAPDAGDYITQ
MQFEITGQLNHAAFSAAWNRTIGHYRMLRTAFVWQDLAEPLQLVLRQAVITIDFQQLPMNSLEQEQVLEAYLQADRTRGF
EPTQAPLMRVALFERAPQRYCCIWTNHHLIIDGWSLPLILDSLFRYYQAEINQQPLELAPEIPYQRYIQWLAQHNDQQAT
AFWRELLRGFTAPTSLALERFGSTHAERHYSASWLQLDSAITQQLQQFARDHGLTVNSLLQAAWALVLSRYSHQTDIVFG
TTTAGRPTDLAGVEQIVGMFVNTLPTRVKWDLQQPVLDWLQALQAQESAVRSYEASSLIEIQACSELPRNSPLFESILVF
ENYPVSSSDLTGLGDLELRLVPSREQTNYPLTLVAVPGDGLAFKLMYQQGYIDQLTSQRMLDYLQQGLAAMLAQPKARLG
QLNIGHPSEIQALADWNATAAPRQTSSLLECFYQQVAAQPTSIAVAWREQRWSYFDLAQASQAIAGYLRDQGVQRQQIIG
LRAERNPQFVAALLAILQLGAVYLPIDPQHPVQRQQQLAQHVDWLLTDALAEAQPQQLDLAQALGYDQPASDFVQLHDRD
LAYVLFTSGSTGTPKGVMIDHAGMLNHIDVMIERLALTQTDCIAQSAAQSFDISVWQLLTALVVGARMQIIDDQTMRDPQ
ALLAKLAAANVSIFEPVPSLIQALLETIASLEQTPSLAALRWVLPTGEHLPRELAQQWFAHYPYIPLLNAYGPAECADDV
TLWPIASAVELPQNAIPIGRPVANVRAYVLDASLRPVPIGVAGELYIAGIAVGWGYLADPQRTASLFLPDPWGEPGARMY
RTGDLARYNQAGVLSFLGRSDQQVKIRGFRIELGEIEACLLQHPALHSVAVAVVGVAEQARLIAYLVAKAKPVSDQLLRD
FVQARLPHYLQPSGYCWLSQLPLNANGKLDRQRLPIPQLQTAERLIIAPQNADQAKLAELWAAILQREQVGINQNFFELG
GHSLLATRLVSQIRQYWQLDLPIRSVFEAPTIEQLADVLDLLRWAQQANQAPAQAREQGAI

Sequences:

>Translated_1661_residues
MPTVLEPITPDALSETLRQYLQAYLPDYMLPAAFVPLEQIPRLPNGKIDRAALPMVDFAAQHEQQTQTAPRNPLEQQLAA
IWQQTLQVPSVGIHDNFFQLGGDSILSIQVIARANRAGIRLTTRQLFEQPTIAQLASLAQTTTIDVAHSELSAGQIVPLT
PIQRWLLADPTDPSQFNQALFLQFTQAIDSNLVASAVEHVAQLHVSLRLRYRRTADGWQQFVAAADAPLVEFEQINAQNL
NPTELAELFEATTERLQRPFDLAKAALWRIAYIAMPDAQPARLLLVMHHLVVDGVSWRIIIQDLAHALQNQPLTKPAVGF
AQWAIALERYAHRTELQQQRAYWLAQTSTDPLPVDDITGHNDYASVATITKQLSQAHTTALIHQASQAYQTQINELLLAA
LTQTITAWSGHADVVLQLEGHGREELDQPLDLSQTVGWFTTLFPIKLSLPQKLGSKNLIKQIKEQIRAVPQRGFGYGLLR
SADAALQAMPTPAISFNYFGQLDQTLQSSKLFSAAPESTGSAVLPQRRREQLLAINCQVLAGQLQIEWSYSQHLHSAATI
ERLAEAYCADLVGLIEHCCQQTQPSFTPADFPLAQITQAQLDQIEQIYPPFEQLYPLSSLQQGILFHRLYAPDAGDYITQ
MQFEITGQLNHAAFSAAWNRTIGHYRMLRTAFVWQDLAEPLQLVLRQAVITIDFQQLPMNSLEQEQVLEAYLQADRTRGF
EPTQAPLMRVALFERAPQRYCCIWTNHHLIIDGWSLPLILDSLFRYYQAEINQQPLELAPEIPYQRYIQWLAQHNDQQAT
AFWRELLRGFTAPTSLALERFGSTHAERHYSASWLQLDSAITQQLQQFARDHGLTVNSLLQAAWALVLSRYSHQTDIVFG
TTTAGRPTDLAGVEQIVGMFVNTLPTRVKWDLQQPVLDWLQALQAQESAVRSYEASSLIEIQACSELPRNSPLFESILVF
ENYPVSSSDLTGLGDLELRLVPSREQTNYPLTLVAVPGDGLAFKLMYQQGYIDQLTSQRMLDYLQQGLAAMLAQPKARLG
QLNIGHPSEIQALADWNATAAPRQTSSLLECFYQQVAAQPTSIAVAWREQRWSYFDLAQASQAIAGYLRDQGVQRQQIIG
LRAERNPQFVAALLAILQLGAVYLPIDPQHPVQRQQQLAQHVDWLLTDALAEAQPQQLDLAQALGYDQPASDFVQLHDRD
LAYVLFTSGSTGTPKGVMIDHAGMLNHIDVMIERLALTQTDCIAQSAAQSFDISVWQLLTALVVGARMQIIDDQTMRDPQ
ALLAKLAAANVSIFEPVPSLIQALLETIASLEQTPSLAALRWVLPTGEHLPRELAQQWFAHYPYIPLLNAYGPAECADDV
TLWPIASAVELPQNAIPIGRPVANVRAYVLDASLRPVPIGVAGELYIAGIAVGWGYLADPQRTASLFLPDPWGEPGARMY
RTGDLARYNQAGVLSFLGRSDQQVKIRGFRIELGEIEACLLQHPALHSVAVAVVGVAEQARLIAYLVAKAKPVSDQLLRD
FVQARLPHYLQPSGYCWLSQLPLNANGKLDRQRLPIPQLQTAERLIIAPQNADQAKLAELWAAILQREQVGINQNFFELG
GHSLLATRLVSQIRQYWQLDLPIRSVFEAPTIEQLADVLDLLRWAQQANQAPAQAREQGAI
>Mature_1660_residues
PTVLEPITPDALSETLRQYLQAYLPDYMLPAAFVPLEQIPRLPNGKIDRAALPMVDFAAQHEQQTQTAPRNPLEQQLAAI
WQQTLQVPSVGIHDNFFQLGGDSILSIQVIARANRAGIRLTTRQLFEQPTIAQLASLAQTTTIDVAHSELSAGQIVPLTP
IQRWLLADPTDPSQFNQALFLQFTQAIDSNLVASAVEHVAQLHVSLRLRYRRTADGWQQFVAAADAPLVEFEQINAQNLN
PTELAELFEATTERLQRPFDLAKAALWRIAYIAMPDAQPARLLLVMHHLVVDGVSWRIIIQDLAHALQNQPLTKPAVGFA
QWAIALERYAHRTELQQQRAYWLAQTSTDPLPVDDITGHNDYASVATITKQLSQAHTTALIHQASQAYQTQINELLLAAL
TQTITAWSGHADVVLQLEGHGREELDQPLDLSQTVGWFTTLFPIKLSLPQKLGSKNLIKQIKEQIRAVPQRGFGYGLLRS
ADAALQAMPTPAISFNYFGQLDQTLQSSKLFSAAPESTGSAVLPQRRREQLLAINCQVLAGQLQIEWSYSQHLHSAATIE
RLAEAYCADLVGLIEHCCQQTQPSFTPADFPLAQITQAQLDQIEQIYPPFEQLYPLSSLQQGILFHRLYAPDAGDYITQM
QFEITGQLNHAAFSAAWNRTIGHYRMLRTAFVWQDLAEPLQLVLRQAVITIDFQQLPMNSLEQEQVLEAYLQADRTRGFE
PTQAPLMRVALFERAPQRYCCIWTNHHLIIDGWSLPLILDSLFRYYQAEINQQPLELAPEIPYQRYIQWLAQHNDQQATA
FWRELLRGFTAPTSLALERFGSTHAERHYSASWLQLDSAITQQLQQFARDHGLTVNSLLQAAWALVLSRYSHQTDIVFGT
TTAGRPTDLAGVEQIVGMFVNTLPTRVKWDLQQPVLDWLQALQAQESAVRSYEASSLIEIQACSELPRNSPLFESILVFE
NYPVSSSDLTGLGDLELRLVPSREQTNYPLTLVAVPGDGLAFKLMYQQGYIDQLTSQRMLDYLQQGLAAMLAQPKARLGQ
LNIGHPSEIQALADWNATAAPRQTSSLLECFYQQVAAQPTSIAVAWREQRWSYFDLAQASQAIAGYLRDQGVQRQQIIGL
RAERNPQFVAALLAILQLGAVYLPIDPQHPVQRQQQLAQHVDWLLTDALAEAQPQQLDLAQALGYDQPASDFVQLHDRDL
AYVLFTSGSTGTPKGVMIDHAGMLNHIDVMIERLALTQTDCIAQSAAQSFDISVWQLLTALVVGARMQIIDDQTMRDPQA
LLAKLAAANVSIFEPVPSLIQALLETIASLEQTPSLAALRWVLPTGEHLPRELAQQWFAHYPYIPLLNAYGPAECADDVT
LWPIASAVELPQNAIPIGRPVANVRAYVLDASLRPVPIGVAGELYIAGIAVGWGYLADPQRTASLFLPDPWGEPGARMYR
TGDLARYNQAGVLSFLGRSDQQVKIRGFRIELGEIEACLLQHPALHSVAVAVVGVAEQARLIAYLVAKAKPVSDQLLRDF
VQARLPHYLQPSGYCWLSQLPLNANGKLDRQRLPIPQLQTAERLIIAPQNADQAKLAELWAAILQREQVGINQNFFELGG
HSLLATRLVSQIRQYWQLDLPIRSVFEAPTIEQLADVLDLLRWAQQANQAPAQAREQGAI

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=442, Percent_Identity=25.7918552036199, Blast_Score=109, Evalue=2e-23,
Organism=Homo sapiens, GI38505220, Length=507, Percent_Identity=22.2879684418146, Blast_Score=96, Evalue=3e-19,
Organism=Homo sapiens, GI115511026, Length=511, Percent_Identity=22.1135029354207, Blast_Score=88, Evalue=8e-17,
Organism=Escherichia coli, GI1786801, Length=1077, Percent_Identity=30.2692664809656, Blast_Score=350, Evalue=6e-97,
Organism=Escherichia coli, GI145693145, Length=528, Percent_Identity=27.4621212121212, Blast_Score=136, Evalue=1e-32,
Organism=Escherichia coli, GI1788107, Length=563, Percent_Identity=24.1563055062167, Blast_Score=106, Evalue=2e-23,
Organism=Escherichia coli, GI1786810, Length=509, Percent_Identity=26.9155206286837, Blast_Score=97, Evalue=7e-21,
Organism=Escherichia coli, GI221142682, Length=509, Percent_Identity=23.3791748526523, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI1790505, Length=552, Percent_Identity=21.9202898550725, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17550940, Length=955, Percent_Identity=21.9895287958115, Blast_Score=139, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17556356, Length=591, Percent_Identity=24.1962774957699, Blast_Score=132, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17559526, Length=387, Percent_Identity=24.8062015503876, Blast_Score=91, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI32564420, Length=416, Percent_Identity=23.0769230769231, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32564422, Length=416, Percent_Identity=23.0769230769231, Blast_Score=82, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560308, Length=423, Percent_Identity=22.9314420803783, Blast_Score=78, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319591, Length=687, Percent_Identity=24.745269286754, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24648676, Length=546, Percent_Identity=28.9377289377289, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24582852, Length=580, Percent_Identity=24.4827586206897, Blast_Score=104, Evalue=5e-22,
Organism=Drosophila melanogaster, GI18859661, Length=370, Percent_Identity=25.1351351351351, Blast_Score=92, Evalue=3e-18,
Organism=Drosophila melanogaster, GI19922652, Length=509, Percent_Identity=23.1827111984283, Blast_Score=76, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581924, Length=357, Percent_Identity=23.8095238095238, Blast_Score=71, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 185340; Mature: 185208

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTVLEPITPDALSETLRQYLQAYLPDYMLPAAFVPLEQIPRLPNGKIDRAALPMVDFAA
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHCCCCCCCCCCHHHCCHHHHHH
QHEQQTQTAPRNPLEQQLAAIWQQTLQVPSVGIHDNFFQLGGDSILSIQVIARANRAGIR
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCEEEEEEEECCCCCCEE
LTTRQLFEQPTIAQLASLAQTTTIDVAHSELSAGQIVPLTPIQRWLLADPTDPSQFNQAL
EEHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHCCCCCHHHHHHHH
FLQFTQAIDSNLVASAVEHVAQLHVSLRLRYRRTADGWQQFVAAADAPLVEFEQINAQNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHCCCCCC
NPTELAELFEATTERLQRPFDLAKAALWRIAYIAMPDAQPARLLLVMHHLVVDGVSWRII
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHCCCHHHHH
IQDLAHALQNQPLTKPAVGFAQWAIALERYAHRTELQQQRAYWLAQTSTDPLPVDDITGH
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCC
NDYASVATITKQLSQAHTTALIHQASQAYQTQINELLLAALTQTITAWSGHADVVLQLEG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
HGREELDQPLDLSQTVGWFTTLFPIKLSLPQKLGSKNLIKQIKEQIRAVPQRGFGYGLLR
CCHHHHCCCCCHHHHHHHHHHHHHHEECCHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHH
SADAALQAMPTPAISFNYFGQLDQTLQSSKLFSAAPESTGSAVLPQRRREQLLAINCQVL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHEEE
AGQLQIEWSYSQHLHSAATIERLAEAYCADLVGLIEHCCQQTQPSFTPADFPLAQITQAQ
EEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
LDQIEQIYPPFEQLYPLSSLQQGILFHRLYAPDAGDYITQMQFEITGQLNHAAFSAAWNR
HHHHHHHCCCHHHHCCHHHHHHHHHHHHHCCCCCCCHHHEEEEEEECCCCHHHHHHHHHH
TIGHYRMLRTAFVWQDLAEPLQLVLRQAVITIDFQQLPMNSLEQEQVLEAYLQADRTRGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHCCCCCCCHHHHHHHHHHHHHCCCC
EPTQAPLMRVALFERAPQRYCCIWTNHHLIIDGWSLPLILDSLFRYYQAEINQQPLELAP
CCHHHHHHHHHHHHHCCCCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHCCCCCHHCCC
EIPYQRYIQWLAQHNDQQATAFWRELLRGFTAPTSLALERFGSTHAERHYSASWLQLDSA
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHCCHHHHHHHHH
ITQQLQQFARDHGLTVNSLLQAAWALVLSRYSHQTDIVFGTTTAGRPTDLAGVEQIVGMF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHH
VNTLPTRVKWDLQQPVLDWLQALQAQESAVRSYEASSLIEIQACSELPRNSPLFESILVF
HHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHCCCCCCCHHHHHHHH
ENYPVSSSDLTGLGDLELRLVPSREQTNYPLTLVAVPGDGLAFKLMYQQGYIDQLTSQRM
CCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEHHCCHHHHHHHHHH
LDYLQQGLAAMLAQPKARLGQLNIGHPSEIQALADWNATAAPRQTSSLLECFYQQVAAQP
HHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
TSIAVAWREQRWSYFDLAQASQAIAGYLRDQGVQRQQIIGLRAERNPQFVAALLAILQLG
CCEEEEEHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHC
AVYLPIDPQHPVQRQQQLAQHVDWLLTDALAEAQPQQLDLAQALGYDQPASDFVQLHDRD
CEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHCCCC
LAYVLFTSGSTGTPKGVMIDHAGMLNHIDVMIERLALTQTDCIAQSAAQSFDISVWQLLT
EEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ALVVGARMQIIDDQTMRDPQALLAKLAAANVSIFEPVPSLIQALLETIASLEQTPSLAAL
HHHHCCHHHEECCHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RWVLPTGEHLPRELAQQWFAHYPYIPLLNAYGPAECADDVTLWPIASAVELPQNAIPIGR
EEECCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCHHCCCCEEHHHHHHHHCCCCCCCCCC
PVANVRAYVLDASLRPVPIGVAGELYIAGIAVGWGYLADPQRTASLFLPDPWGEPGARMY
CHHHHHHHEEECCCCCCEECCCCCCEEEEHHHCCCCCCCCCCCCEEECCCCCCCCCCCEE
RTGDLARYNQAGVLSFLGRSDQQVKIRGFRIELGEIEACLLQHPALHSVAVAVVGVAEQA
ECCCCHHCCCCHHHHHHCCCCCEEEEEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHH
RLIAYLVAKAKPVSDQLLRDFVQARLPHYLQPSGYCWLSQLPLNANGKLDRQRLPIPQLQ
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
TAERLIIAPQNADQAKLAELWAAILQREQVGINQNFFELGGHSLLATRLVSQIRQYWQLD
CCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCC
LPIRSVFEAPTIEQLADVLDLLRWAQQANQAPAQAREQGAI
CCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCC
>Mature Secondary Structure 
PTVLEPITPDALSETLRQYLQAYLPDYMLPAAFVPLEQIPRLPNGKIDRAALPMVDFAA
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHCCCCCCCCCCHHHCCHHHHHH
QHEQQTQTAPRNPLEQQLAAIWQQTLQVPSVGIHDNFFQLGGDSILSIQVIARANRAGIR
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCEEEEEEEECCCCCCEE
LTTRQLFEQPTIAQLASLAQTTTIDVAHSELSAGQIVPLTPIQRWLLADPTDPSQFNQAL
EEHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHCCCCCHHHHHHHH
FLQFTQAIDSNLVASAVEHVAQLHVSLRLRYRRTADGWQQFVAAADAPLVEFEQINAQNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHCCCCCC
NPTELAELFEATTERLQRPFDLAKAALWRIAYIAMPDAQPARLLLVMHHLVVDGVSWRII
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHCCCHHHHH
IQDLAHALQNQPLTKPAVGFAQWAIALERYAHRTELQQQRAYWLAQTSTDPLPVDDITGH
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCC
NDYASVATITKQLSQAHTTALIHQASQAYQTQINELLLAALTQTITAWSGHADVVLQLEG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
HGREELDQPLDLSQTVGWFTTLFPIKLSLPQKLGSKNLIKQIKEQIRAVPQRGFGYGLLR
CCHHHHCCCCCHHHHHHHHHHHHHHEECCHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHH
SADAALQAMPTPAISFNYFGQLDQTLQSSKLFSAAPESTGSAVLPQRRREQLLAINCQVL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHEEE
AGQLQIEWSYSQHLHSAATIERLAEAYCADLVGLIEHCCQQTQPSFTPADFPLAQITQAQ
EEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
LDQIEQIYPPFEQLYPLSSLQQGILFHRLYAPDAGDYITQMQFEITGQLNHAAFSAAWNR
HHHHHHHCCCHHHHCCHHHHHHHHHHHHHCCCCCCCHHHEEEEEEECCCCHHHHHHHHHH
TIGHYRMLRTAFVWQDLAEPLQLVLRQAVITIDFQQLPMNSLEQEQVLEAYLQADRTRGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHCCCCCCCHHHHHHHHHHHHHCCCC
EPTQAPLMRVALFERAPQRYCCIWTNHHLIIDGWSLPLILDSLFRYYQAEINQQPLELAP
CCHHHHHHHHHHHHHCCCCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHCCCCCHHCCC
EIPYQRYIQWLAQHNDQQATAFWRELLRGFTAPTSLALERFGSTHAERHYSASWLQLDSA
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHCCHHHHHHHHH
ITQQLQQFARDHGLTVNSLLQAAWALVLSRYSHQTDIVFGTTTAGRPTDLAGVEQIVGMF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHH
VNTLPTRVKWDLQQPVLDWLQALQAQESAVRSYEASSLIEIQACSELPRNSPLFESILVF
HHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHCCCCCCCHHHHHHHH
ENYPVSSSDLTGLGDLELRLVPSREQTNYPLTLVAVPGDGLAFKLMYQQGYIDQLTSQRM
CCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEHHCCHHHHHHHHHH
LDYLQQGLAAMLAQPKARLGQLNIGHPSEIQALADWNATAAPRQTSSLLECFYQQVAAQP
HHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
TSIAVAWREQRWSYFDLAQASQAIAGYLRDQGVQRQQIIGLRAERNPQFVAALLAILQLG
CCEEEEEHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHC
AVYLPIDPQHPVQRQQQLAQHVDWLLTDALAEAQPQQLDLAQALGYDQPASDFVQLHDRD
CEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHCCCC
LAYVLFTSGSTGTPKGVMIDHAGMLNHIDVMIERLALTQTDCIAQSAAQSFDISVWQLLT
EEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ALVVGARMQIIDDQTMRDPQALLAKLAAANVSIFEPVPSLIQALLETIASLEQTPSLAAL
HHHHCCHHHEECCHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RWVLPTGEHLPRELAQQWFAHYPYIPLLNAYGPAECADDVTLWPIASAVELPQNAIPIGR
EEECCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCHHCCCCEEHHHHHHHHCCCCCCCCCC
PVANVRAYVLDASLRPVPIGVAGELYIAGIAVGWGYLADPQRTASLFLPDPWGEPGARMY
CHHHHHHHEEECCCCCCEECCCCCCEEEEHHHCCCCCCCCCCCCEEECCCCCCCCCCCEE
RTGDLARYNQAGVLSFLGRSDQQVKIRGFRIELGEIEACLLQHPALHSVAVAVVGVAEQA
ECCCCHHCCCCHHHHHHCCCCCEEEEEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHH
RLIAYLVAKAKPVSDQLLRDFVQARLPHYLQPSGYCWLSQLPLNANGKLDRQRLPIPQLQ
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
TAERLIIAPQNADQAKLAELWAAILQREQVGINQNFFELGGHSLLATRLVSQIRQYWQLD
CCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCC
LPIRSVFEAPTIEQLADVLDLLRWAQQANQAPAQAREQGAI
CCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA