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The map label for this gene is dhbF [H]

Identifier: 159898612

GI number: 159898612

Start: 2609700

End: 2613137

Strand: Reverse

Name: dhbF [H]

Synonym: Haur_2091

Alternate gene names: 159898612

Gene position: 2613137-2609700 (Counterclockwise)

Preceding gene: 159898613

Following gene: 159898611

Centisome position: 41.17

GC content: 50.32

Gene sequence:

>3438_bases
ATGTGGCAATTGTTGACCCAATTACGGGCAGCCGATATTCGGATTTGGCTTGAAGGCGAGCGCTTATGCTACGATGCCCC
ACCAGGCGTACTAAGTGAGCAACTATTAAGCCAATTACGCCAGCATAAGGCCGAACTATGCCAATTTTTGGCGCGAACTC
AGCCCAATCAATTTGCGCCGATTCCAAGGCTGGAAGATGATCAACCTGTGGCGCTAAGCTTTGCCCAGCAACGGTTGTGG
TTTTTGCATGAATTTGCCCCCACCAGCACGGCTTATCATCTTCCGGCGGCAATTGAACTCAATGGCGAGTTGGATCGTAC
AGCCTTGCACCAGAGTTTCGAGCAACTGATCGAACGCCATACAATCTTACGGAGCCATGTGCTGTGGCAGGATGGCCAGC
CATTGCAACAGGTCGCCGCCAATTGGCAGTTACCTTGGGCTTTTTATGATCTGCGTTCAGCCAATGATCCTGCGGCTGAA
TGCTATCAGCAGTTGTTGGCAGCCTTTGAAGCACCCTTCGATCTCGCGATTGCGCCATCGCTGCGTTGCGTTTTAGTCTG
CTTAGCAGAAAAACAGCATATTCTTTTGGTCACACAGCACCATTGGATTAGCGATGGCTGGTCGATTGGAATTATGATCA
ACGAGCTAGCCCACATCTATCGAGCAACATTGAACCAACAACCGCATCAGCTACCAACCTTACCGGTGCAATATCGTGAT
TTGGCGGTCTGGCAGCGCCAACAATTGCAGGGAGCAAAGTTAACGCAATTGTTGACGTACTGGCGACAACAATTGGCCGA
TTTGCCCAATTTGGCGTTGCCTTACGAAGCCCAAAAGCCCGCCCAAACGATGTCAACCAGCATTCCAATCCAACTTGATC
GCGCCTTGGTCGAACGCTTAACCAACCTAAACCAAACTCATGGCACGACCATGTTTATGAGCTTGTTGGCGGGCTTTTTT
GCGCTGTTAAGCCGTTATACGCAGCAACACGATTTTGCGGTTGGTTCGCCGATTGCTGGGCGTTTGCAGCCTGAAGCTGA
GCCTTTAATTGGTTGTTTTATCAATAGTTTAGTGCTACGAGCTGATTTAAGTGGCCAGCCCAGCTTTCGTCAATTGTTGG
AGCGGGTGCGCCAAACCAGCTTGGCGGCCTATGCACACCAAGAATTGCCGTTTGAATTGCTAGTTGAGGCCTTGCAGCCT
GAGCGCAAACTCGATCAACAACCCCTATTTCAAGCGCTATTTGCTCTGCAAAATATGCCAACTGGCCAGCTTGAAGCCCC
AAATCTGGTAATCAAACCCTATGCATTTGCCCAACAAGCGCCTCAATTTCCGCTTAGTCTGATCTTGTTTGAGCAAGCGG
GTCAGATTACGGGCGAGCTGAATTATGATCCACAACAGCTATCGCAGCAGTTTGCCAGCCAATTTGCCGCGCACTATGCC
CAATTCTTGACGCAGTTGCTGGTAGAACCAGATACGGCAATCGCTCAGCTGAAATTATTGCAGCAACCTGAACAGGATAA
GGTGCTCAATCTACTAAATTCAAATCGGCAAGTTTACCCGATCAACAATAGTTTAGTTGCACGTTTTACCCAACAAGCGC
TGGCAACGCCCCAAGCAATTGCCTTGAGTTATGCCGAGCAAGCGATCAGCTACCAACAATTGGCCGAAGCTGCCGATCAA
TTGGTCTATGTGCTTTTGGCCCAAGGTGTACAACCTGAACAACCAATCGGCTTGTTGTGTGAGCGTTCGCCGCAATTAAT
TATTGGCATTTTGGGAATTCTCAAGGCTGGCGCAGCCTATCTGCCGCTCGATCCGCAGTTGCCTACCAGCCGAATCGAAT
GGATGCTGGCCGATGCCCAAGTTAATTTAATTGTTACTCAAAACAGTCTGTTGCACAGTGTTAATTCACAAGCAACCACC
ATTCTCAACCTTGATCAACTTCCAACCACCAAACTCACTCAATTACCAACTATCCATCCCGATCAACTTGCCTATATCAT
TTATACCTCTGGCTCAACTGGGCAACCCAAAGGCACGTTGTTGAGCCATGCCAACGTGTTGCGCTTATTCGAGGCGACAG
TTGCTACGATTAAACCTAGTGCCAATGATGTTTGGAGCTTATTCCATTCATATGCATTCGATTTTTCGGTTTGGGAAATT
TGGGGGGCATTGCTGTATGGTGGACGTTTGGTGGTTGTGCCAAGTACCACAACTCGCTCACCCGAAGCGTTCAGCCAATT
GTTGGCAGACGAATCGATAACTGTGCTCAATCAAACACCCTCGGCGTTTCGTCAACTATTACCCCAACTCACGCCAGCGG
TGGCCGCGAATTTGGCGCTGCGCTTGATTATCTTTGGTGGCGAGGCGCTTGATCTGGCCAGCCTCGCCGCTTGGTATCAA
GCCTATCCTGCGCCCGCCCCGCAACTGCTGAATATGTATGGCATCACCGAAACTACGGTGCATGTGACTGAGCGTTGGTT
GGAGCTTAATGACTTGATCGAGGCAAAAGCCAGCCTAATCGGCTTGCCAATCGCCGACTTAACCATGTATCTGCTCGATC
AGTACGGCCAACTTGTGCCTCAAGGTGCAGTCGGCGAGATCTATGTGGGCGGGGCAGGTTTGGCGCGGGGCTATCTCAAG
CAAGCGGCGTTGACCGCCCAACGCTTTGTGCCTGATCCATGGTCAAGCACTGGGGCACGGCTCTACCGCAGCGGCGATTT
GGCTCGGATTAATCAATTTGGCGAGCTAGAATACCTTGGGCGTAGTGATCAGCAAGTCAAATTGCGCGGCTTTCGGATTG
AGCTAGGCGAACTTGAACAAGCGATTTGCCGCCAAGCAGGAGTTGCTGATTGCTGGGCGTTTGTGCAAAAACTTGATCAA
CACGAGCGCCTAGTAGTTTGGGTTGTGCCAAATCAGCCAGCGCTTAGCGTTGAACAATTGCGCCAAGCGCTGGCTCTCGA
GCTGCCCCATTATCTGCAACCCAATCTCTGGCTGCTGTGCGAACACTTGCCGCTTACCAACAACGGCAAACGCGATTATG
CTCATTTATTAGCGCAACTTGACGTAACGCTTGAGCAAGCATCAAGTATTGCCCCCAATAATCCAATTCAAGCGCTGATT
GCAGCAATTTGGCTTGAGATTTTGCAGCAACCAATTGCCAGCATTGATCAAAACTTTTTCGAGGTTGGCGGTAATTCGTT
GAATGCGGTTTTGGTGCTAACCCGCATTCGCGAATTATTACGGGTCAATCTGAGTTTGCGCAGCCTATTTGCCCAACCAA
CCATTCGCGGTGTTGAACAAGCCTTAGTACAGCAAGAACCCAAGCCTGGCCAAACTGCCAAAATTGCCGAGTTGGTGCAA
AAACTCCAGCAAGCTACACCTGAGCAGCGCCAACAAGCCTTAGCATCCAAGCGCCAAGAACGGACGGTCGGCGAATGA

Upstream 100 bases:

>100_bases
CGACAATCGAACAACTGGCTGATGTGCTTGATCTCCTACGCTGGGCGCAACAGGCTAATCAAGCTCCAGCTCAAGCCCGC
GAACAAGGAGCAATTTAATC

Downstream 100 bases:

>100_bases
GCTATTCAAATATTACCCAACTCGTGACCGCTCAAGCCAACCAAACGCCTGCCGCTTGGGCAGTGCAAACGCCTACAGGT
TATGGATTAACCTTTGCCGA

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1145; Mature: 1145

Protein sequence:

>1145_residues
MWQLLTQLRAADIRIWLEGERLCYDAPPGVLSEQLLSQLRQHKAELCQFLARTQPNQFAPIPRLEDDQPVALSFAQQRLW
FLHEFAPTSTAYHLPAAIELNGELDRTALHQSFEQLIERHTILRSHVLWQDGQPLQQVAANWQLPWAFYDLRSANDPAAE
CYQQLLAAFEAPFDLAIAPSLRCVLVCLAEKQHILLVTQHHWISDGWSIGIMINELAHIYRATLNQQPHQLPTLPVQYRD
LAVWQRQQLQGAKLTQLLTYWRQQLADLPNLALPYEAQKPAQTMSTSIPIQLDRALVERLTNLNQTHGTTMFMSLLAGFF
ALLSRYTQQHDFAVGSPIAGRLQPEAEPLIGCFINSLVLRADLSGQPSFRQLLERVRQTSLAAYAHQELPFELLVEALQP
ERKLDQQPLFQALFALQNMPTGQLEAPNLVIKPYAFAQQAPQFPLSLILFEQAGQITGELNYDPQQLSQQFASQFAAHYA
QFLTQLLVEPDTAIAQLKLLQQPEQDKVLNLLNSNRQVYPINNSLVARFTQQALATPQAIALSYAEQAISYQQLAEAADQ
LVYVLLAQGVQPEQPIGLLCERSPQLIIGILGILKAGAAYLPLDPQLPTSRIEWMLADAQVNLIVTQNSLLHSVNSQATT
ILNLDQLPTTKLTQLPTIHPDQLAYIIYTSGSTGQPKGTLLSHANVLRLFEATVATIKPSANDVWSLFHSYAFDFSVWEI
WGALLYGGRLVVVPSTTTRSPEAFSQLLADESITVLNQTPSAFRQLLPQLTPAVAANLALRLIIFGGEALDLASLAAWYQ
AYPAPAPQLLNMYGITETTVHVTERWLELNDLIEAKASLIGLPIADLTMYLLDQYGQLVPQGAVGEIYVGGAGLARGYLK
QAALTAQRFVPDPWSSTGARLYRSGDLARINQFGELEYLGRSDQQVKLRGFRIELGELEQAICRQAGVADCWAFVQKLDQ
HERLVVWVVPNQPALSVEQLRQALALELPHYLQPNLWLLCEHLPLTNNGKRDYAHLLAQLDVTLEQASSIAPNNPIQALI
AAIWLEILQQPIASIDQNFFEVGGNSLNAVLVLTRIRELLRVNLSLRSLFAQPTIRGVEQALVQQEPKPGQTAKIAELVQ
KLQQATPEQRQQALASKRQERTVGE

Sequences:

>Translated_1145_residues
MWQLLTQLRAADIRIWLEGERLCYDAPPGVLSEQLLSQLRQHKAELCQFLARTQPNQFAPIPRLEDDQPVALSFAQQRLW
FLHEFAPTSTAYHLPAAIELNGELDRTALHQSFEQLIERHTILRSHVLWQDGQPLQQVAANWQLPWAFYDLRSANDPAAE
CYQQLLAAFEAPFDLAIAPSLRCVLVCLAEKQHILLVTQHHWISDGWSIGIMINELAHIYRATLNQQPHQLPTLPVQYRD
LAVWQRQQLQGAKLTQLLTYWRQQLADLPNLALPYEAQKPAQTMSTSIPIQLDRALVERLTNLNQTHGTTMFMSLLAGFF
ALLSRYTQQHDFAVGSPIAGRLQPEAEPLIGCFINSLVLRADLSGQPSFRQLLERVRQTSLAAYAHQELPFELLVEALQP
ERKLDQQPLFQALFALQNMPTGQLEAPNLVIKPYAFAQQAPQFPLSLILFEQAGQITGELNYDPQQLSQQFASQFAAHYA
QFLTQLLVEPDTAIAQLKLLQQPEQDKVLNLLNSNRQVYPINNSLVARFTQQALATPQAIALSYAEQAISYQQLAEAADQ
LVYVLLAQGVQPEQPIGLLCERSPQLIIGILGILKAGAAYLPLDPQLPTSRIEWMLADAQVNLIVTQNSLLHSVNSQATT
ILNLDQLPTTKLTQLPTIHPDQLAYIIYTSGSTGQPKGTLLSHANVLRLFEATVATIKPSANDVWSLFHSYAFDFSVWEI
WGALLYGGRLVVVPSTTTRSPEAFSQLLADESITVLNQTPSAFRQLLPQLTPAVAANLALRLIIFGGEALDLASLAAWYQ
AYPAPAPQLLNMYGITETTVHVTERWLELNDLIEAKASLIGLPIADLTMYLLDQYGQLVPQGAVGEIYVGGAGLARGYLK
QAALTAQRFVPDPWSSTGARLYRSGDLARINQFGELEYLGRSDQQVKLRGFRIELGELEQAICRQAGVADCWAFVQKLDQ
HERLVVWVVPNQPALSVEQLRQALALELPHYLQPNLWLLCEHLPLTNNGKRDYAHLLAQLDVTLEQASSIAPNNPIQALI
AAIWLEILQQPIASIDQNFFEVGGNSLNAVLVLTRIRELLRVNLSLRSLFAQPTIRGVEQALVQQEPKPGQTAKIAELVQ
KLQQATPEQRQQALASKRQERTVGE
>Mature_1145_residues
MWQLLTQLRAADIRIWLEGERLCYDAPPGVLSEQLLSQLRQHKAELCQFLARTQPNQFAPIPRLEDDQPVALSFAQQRLW
FLHEFAPTSTAYHLPAAIELNGELDRTALHQSFEQLIERHTILRSHVLWQDGQPLQQVAANWQLPWAFYDLRSANDPAAE
CYQQLLAAFEAPFDLAIAPSLRCVLVCLAEKQHILLVTQHHWISDGWSIGIMINELAHIYRATLNQQPHQLPTLPVQYRD
LAVWQRQQLQGAKLTQLLTYWRQQLADLPNLALPYEAQKPAQTMSTSIPIQLDRALVERLTNLNQTHGTTMFMSLLAGFF
ALLSRYTQQHDFAVGSPIAGRLQPEAEPLIGCFINSLVLRADLSGQPSFRQLLERVRQTSLAAYAHQELPFELLVEALQP
ERKLDQQPLFQALFALQNMPTGQLEAPNLVIKPYAFAQQAPQFPLSLILFEQAGQITGELNYDPQQLSQQFASQFAAHYA
QFLTQLLVEPDTAIAQLKLLQQPEQDKVLNLLNSNRQVYPINNSLVARFTQQALATPQAIALSYAEQAISYQQLAEAADQ
LVYVLLAQGVQPEQPIGLLCERSPQLIIGILGILKAGAAYLPLDPQLPTSRIEWMLADAQVNLIVTQNSLLHSVNSQATT
ILNLDQLPTTKLTQLPTIHPDQLAYIIYTSGSTGQPKGTLLSHANVLRLFEATVATIKPSANDVWSLFHSYAFDFSVWEI
WGALLYGGRLVVVPSTTTRSPEAFSQLLADESITVLNQTPSAFRQLLPQLTPAVAANLALRLIIFGGEALDLASLAAWYQ
AYPAPAPQLLNMYGITETTVHVTERWLELNDLIEAKASLIGLPIADLTMYLLDQYGQLVPQGAVGEIYVGGAGLARGYLK
QAALTAQRFVPDPWSSTGARLYRSGDLARINQFGELEYLGRSDQQVKLRGFRIELGELEQAICRQAGVADCWAFVQKLDQ
HERLVVWVVPNQPALSVEQLRQALALELPHYLQPNLWLLCEHLPLTNNGKRDYAHLLAQLDVTLEQASSIAPNNPIQALI
AAIWLEILQQPIASIDQNFFEVGGNSLNAVLVLTRIRELLRVNLSLRSLFAQPTIRGVEQALVQQEPKPGQTAKIAELVQ
KLQQATPEQRQQALASKRQERTVGE

Specific function: Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=595, Percent_Identity=24.5378151260504, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI187761345, Length=499, Percent_Identity=21.8436873747495, Blast_Score=71, Evalue=5e-12,
Organism=Homo sapiens, GI187761343, Length=499, Percent_Identity=21.8436873747495, Blast_Score=71, Evalue=5e-12,
Organism=Homo sapiens, GI157311624, Length=430, Percent_Identity=21.6279069767442, Blast_Score=71, Evalue=6e-12,
Organism=Homo sapiens, GI157311622, Length=430, Percent_Identity=21.6279069767442, Blast_Score=71, Evalue=6e-12,
Organism=Escherichia coli, GI1786801, Length=1040, Percent_Identity=28.5576923076923, Blast_Score=281, Evalue=2e-76,
Organism=Escherichia coli, GI145693145, Length=524, Percent_Identity=26.9083969465649, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI1788107, Length=543, Percent_Identity=23.572744014733, Blast_Score=99, Evalue=2e-21,
Organism=Escherichia coli, GI1786810, Length=517, Percent_Identity=27.0793036750484, Blast_Score=94, Evalue=7e-20,
Organism=Escherichia coli, GI1789201, Length=371, Percent_Identity=25.0673854447439, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI221142682, Length=499, Percent_Identity=21.2424849699399, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17550940, Length=993, Percent_Identity=22.2557905337362, Blast_Score=159, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI17556356, Length=556, Percent_Identity=27.3381294964029, Blast_Score=156, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17560308, Length=368, Percent_Identity=25.5434782608696, Blast_Score=93, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI32563687, Length=434, Percent_Identity=23.7327188940092, Blast_Score=88, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994690, Length=386, Percent_Identity=24.8704663212435, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71994703, Length=386, Percent_Identity=24.8704663212435, Blast_Score=80, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71994694, Length=386, Percent_Identity=24.8704663212435, Blast_Score=80, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32564422, Length=287, Percent_Identity=24.7386759581882, Blast_Score=76, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32564420, Length=287, Percent_Identity=24.7386759581882, Blast_Score=76, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319591, Length=893, Percent_Identity=23.5162374020157, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24648676, Length=609, Percent_Identity=29.5566502463054, Blast_Score=215, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24582852, Length=589, Percent_Identity=23.5993208828523, Blast_Score=100, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 127975; Mature: 127975

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWQLLTQLRAADIRIWLEGERLCYDAPPGVLSEQLLSQLRQHKAELCQFLARTQPNQFAP
CHHHHHHHHHCCEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IPRLEDDQPVALSFAQQRLWFLHEFAPTSTAYHLPAAIELNGELDRTALHQSFEQLIERH
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCEEEEECCCHHHHHHHHHHHHHHHHH
TILRSHVLWQDGQPLQQVAANWQLPWAFYDLRSANDPAAECYQQLLAAFEAPFDLAIAPS
HHHHHHHHCCCCCHHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCH
LRCVLVCLAEKQHILLVTQHHWISDGWSIGIMINELAHIYRATLNQQPHQLPTLPVQYRD
HHHHHHHHCCCCEEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
LAVWQRQQLQGAKLTQLLTYWRQQLADLPNLALPYEAQKPAQTMSTSIPIQLDRALVERL
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHH
TNLNQTHGTTMFMSLLAGFFALLSRYTQQHDFAVGSPIAGRLQPEAEPLIGCFINSLVLR
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ADLSGQPSFRQLLERVRQTSLAAYAHQELPFELLVEALQPERKLDQQPLFQALFALQNMP
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHCCCCHHHHHHHHHHCCC
TGQLEAPNLVIKPYAFAQQAPQFPLSLILFEQAGQITGELNYDPQQLSQQFASQFAAHYA
CCCCCCCCEEECCHHHHHCCCCCCHHHHEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
QFLTQLLVEPDTAIAQLKLLQQPEQDKVLNLLNSNRQVYPINNSLVARFTQQALATPQAI
HHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCHHHH
ALSYAEQAISYQQLAEAADQLVYVLLAQGVQPEQPIGLLCERSPQLIIGILGILKAGAAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCEE
LPLDPQLPTSRIEWMLADAQVNLIVTQNSLLHSVNSQATTILNLDQLPTTKLTQLPTIHP
CCCCCCCCHHHHHEEEECCEEEEEEECHHHHHHCCCCCEEEEECCCCCCCHHHCCCCCCC
DQLAYIIYTSGSTGQPKGTLLSHANVLRLFEATVATIKPSANDVWSLFHSYAFDFSVWEI
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHH
WGALLYGGRLVVVPSTTTRSPEAFSQLLADESITVLNQTPSAFRQLLPQLTPAVAANLAL
HHHHHHCCEEEEECCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHE
RLIIFGGEALDLASLAAWYQAYPAPAPQLLNMYGITETTVHVTERWLELNDLIEAKASLI
EEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
GLPIADLTMYLLDQYGQLVPQGAVGEIYVGGAGLARGYLKQAALTAQRFVPDPWSSTGAR
CCCHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
LYRSGDLARINQFGELEYLGRSDQQVKLRGFRIELGELEQAICRQAGVADCWAFVQKLDQ
HHCCCCHHHHHHCCCHHCCCCCCCEEEEEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHCC
HERLVVWVVPNQPALSVEQLRQALALELPHYLQPNLWLLCEHLPLTNNGKRDYAHLLAQL
CCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHCCCCEEEEECCCCCCCCCHHHHHHHHHH
DVTLEQASSIAPNNPIQALIAAIWLEILQQPIASIDQNFFEVGGNSLNAVLVLTRIRELL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RVNLSLRSLFAQPTIRGVEQALVQQEPKPGQTAKIAELVQKLQQATPEQRQQALASKRQE
HHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RTVGE
CCCCC
>Mature Secondary Structure
MWQLLTQLRAADIRIWLEGERLCYDAPPGVLSEQLLSQLRQHKAELCQFLARTQPNQFAP
CHHHHHHHHHCCEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IPRLEDDQPVALSFAQQRLWFLHEFAPTSTAYHLPAAIELNGELDRTALHQSFEQLIERH
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCEEEEECCCHHHHHHHHHHHHHHHHH
TILRSHVLWQDGQPLQQVAANWQLPWAFYDLRSANDPAAECYQQLLAAFEAPFDLAIAPS
HHHHHHHHCCCCCHHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCH
LRCVLVCLAEKQHILLVTQHHWISDGWSIGIMINELAHIYRATLNQQPHQLPTLPVQYRD
HHHHHHHHCCCCEEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
LAVWQRQQLQGAKLTQLLTYWRQQLADLPNLALPYEAQKPAQTMSTSIPIQLDRALVERL
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHH
TNLNQTHGTTMFMSLLAGFFALLSRYTQQHDFAVGSPIAGRLQPEAEPLIGCFINSLVLR
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ADLSGQPSFRQLLERVRQTSLAAYAHQELPFELLVEALQPERKLDQQPLFQALFALQNMP
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHCCCCHHHHHHHHHHCCC
TGQLEAPNLVIKPYAFAQQAPQFPLSLILFEQAGQITGELNYDPQQLSQQFASQFAAHYA
CCCCCCCCEEECCHHHHHCCCCCCHHHHEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
QFLTQLLVEPDTAIAQLKLLQQPEQDKVLNLLNSNRQVYPINNSLVARFTQQALATPQAI
HHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCHHHH
ALSYAEQAISYQQLAEAADQLVYVLLAQGVQPEQPIGLLCERSPQLIIGILGILKAGAAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCEE
LPLDPQLPTSRIEWMLADAQVNLIVTQNSLLHSVNSQATTILNLDQLPTTKLTQLPTIHP
CCCCCCCCHHHHHEEEECCEEEEEEECHHHHHHCCCCCEEEEECCCCCCCHHHCCCCCCC
DQLAYIIYTSGSTGQPKGTLLSHANVLRLFEATVATIKPSANDVWSLFHSYAFDFSVWEI
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHH
WGALLYGGRLVVVPSTTTRSPEAFSQLLADESITVLNQTPSAFRQLLPQLTPAVAANLAL
HHHHHHCCEEEEECCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHE
RLIIFGGEALDLASLAAWYQAYPAPAPQLLNMYGITETTVHVTERWLELNDLIEAKASLI
EEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
GLPIADLTMYLLDQYGQLVPQGAVGEIYVGGAGLARGYLKQAALTAQRFVPDPWSSTGAR
CCCHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
LYRSGDLARINQFGELEYLGRSDQQVKLRGFRIELGELEQAICRQAGVADCWAFVQKLDQ
HHCCCCHHHHHHCCCHHCCCCCCCEEEEEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHCC
HERLVVWVVPNQPALSVEQLRQALALELPHYLQPNLWLLCEHLPLTNNGKRDYAHLLAQL
CCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHCCCCEEEEECCCCCCCCCHHHHHHHHHH
DVTLEQASSIAPNNPIQALIAAIWLEILQQPIASIDQNFFEVGGNSLNAVLVLTRIRELL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RVNLSLRSLFAQPTIRGVEQALVQQEPKPGQTAKIAELVQKLQQATPEQRQQALASKRQE
HHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RTVGE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11112781; 9384377; 10568751; 8550523 [H]