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The map label for this gene is lgrB [H]

Identifier: 159898611

GI number: 159898611

Start: 2606263

End: 2609703

Strand: Reverse

Name: lgrB [H]

Synonym: Haur_2090

Alternate gene names: 159898611

Gene position: 2609703-2606263 (Counterclockwise)

Preceding gene: 159898612

Following gene: 159898610

Centisome position: 41.12

GC content: 52.43

Gene sequence:

>3441_bases
ATGAGCTATTCAAATATTACCCAACTCGTGACCGCTCAAGCCAACCAAACGCCTGCCGCTTGGGCAGTGCAAACGCCTAC
AGGTTATGGATTAACCTTTGCCGATCTTGAGCAACAATCTAGCCAAGCAGCGGCCTATTTGCAACATCTTGGTGTACAAC
CAGCGAGTGTTGTGGGCATTTGTTTGCGCCGCACGCCACAGCTCATCGTGTGGATGCTGGCAATTCTCAAGGCTGGTGCG
ACCTATCTGCCGCTTGATCCGGCCTATCCAACCGCGCGGTTGCAATTTATGCTGGCCGATGCCAAGGCCTTGCTGGTCGT
CAGCGAAACGTCATGCCAAGCAGCTTTACCCCTGAATACCATTGAGTGGGTGTTGATTGATCAGCCTTGGTCGAGGGAGT
TGGCATGGCGCGAACCCTTCTATCATAGCGCAATCCCTGCTTATATCATCTATACCTCTGGCTCAACCGGCCAACCCAAA
GGTGTGCTGATTAGCCATGCCAATGCGCTCACCTTTTTAGCATGGGCTGAAACCACGTTTAGCGTAGCCGAACGCGCTGG
AATTTTAGCGGCAACCTCGATCAACTTTGATCTTTCGATCTTCGAGATTTTTCTGCCATTGATTAGTGGCGGTACGTTGG
TGCTGGTGGAAAATCTGCTTGATCCAGCGCTGTTTCACTCGCAGCATCCGATTTGTTTGATCAATAGCGTGCCGTCGGCG
GTGCAAACGTTGTTGCAACATACGGCACTTCCATCTAGCGTGCTCACGGTGAATCTTGCCGGCGAGCCGCTGAGCTTGCG
ATTAGCGCAGCAACTCTATCAACAGCCAAACATCCAGCGCGTATTCAATTTATATGGGCCAACCGAGGCCACGACCTATG
CCACCTACCAGCTCGTTGAGCGCACTGCCAGCCGGCCGCCAGCGATTGGTCAGCCGCTCACTGGCACGACCTGCGTTATC
CTCGATGCGCACTATCACCCTGTTGCCGCTAAGGATGTTGGCGAATTGTTTATTGCTGGGCTGGGCGTAGCGCAAGGCTA
TTTGCAACGCCCCGATTTAACTGCCGAACGTTTTTTGCCCAATCCGTGGGCTACCACGCCTGGCGAACGAATGTATAAAA
CTGGCGATTTGGCTCATTGGAACGCGGCAAACGAGCTTTGTTACCTAGGACGTAACGATCAGCAGGTCAAAATTCGTGGC
TTTCGGATCGAGCTTGGTGAGATTGAGGCCCAGATTCTGCGCTTAGCACCATTGCAAGCGGTTGTGGTTCAGCCAATTAC
GCTGGTGGCTGATGATCCGCAGTTGACCGCCTATCTGGTTGCTAATCAGCCGATCGATTGCGAAGCCTTACGCGCTAGCT
TAGCCCACCATGTGCCAAGCTATATGCTACCAAGTTTTTGGGTACAGCTGGCCGAACTGCCATTAACACCCAATGGCAAG
CTTGATCGAGCGGCCTTGCCATGCCCTGATGCCCCAATTAAACAACCATTGCAAAGCTCAACTGAACAGCGTTTGGCGAT
AATCTGGCGCGAAATCTTGGGCGTGGAACAGCTTGGGCGTGAGAGTAATTTTTTGCAGCTTGGTGGTCATTCGCTCAATG
TGATGCAAGTGCTCAAACGAATTGAGCAGACGTGGCAGCTTCAGCTTTCGATTACGCGCTTGTTTGAGCAACCAACCTTG
GCAGCTTGGGCGCGGTTAATCGATCAGCAGCAGCAAGCCTTTGCTCAGGCTGAACCTCAATTCTATCAGCGCACTACGCA
ATTGCATCAGCTTTCGTTTGGCCAACAACGCCTGTGGTTTGCCGAGCAATTACACCCAAACACCGCCTACAACGTCATCC
ACGCATGGCGCATCGATGCTCTGCTTGATGCGGTTGCGCTTGAACAAAGCTGGCTAAGGCTGATCGAACGTCATGAAATG
TTACGCAGCAGCATTCAGCTCATCGCGGGTATTCCACAACAAACGATCATGCTCAAGCCAGTTTGGCAGCTCCAATCTGC
GCCGCAGGCAAGCTTAGAATACTTGTTAAGGTTGCTTGATCGGCCATTCGATTTGGCGCAAGCCCCATTGTTACGGGTTG
GCTTGGCGCAACACCACGATCACGCCATCATGCTGGTAGTTATCCACCATAGCATTATTGATGCTTGGTCGTTGGGCGTG
CTGTGGGCTGAATTAAGTCAGCTGTATGCAAGCTTCTTCGAAAACCAACCAATTCAGCTGCCAAGCCAAGCCTACGATTA
CCTTGATTTTGTGGCTTGGCAGCGCCAGCAGCTTGATTCGGCGTGCTTAGCCCAATTGCAAACCTACTGGCAAACCCAGC
TTGCCCAGCTTGATCCGCTCCCAGCTTTGGCGACCGATTACCCCCGTTCGACGCACATGCAGGGCTTGGGCATCAGCCAA
ACCTATCAACTTGATCAGCAGGTTATCCAAGCATTACAAGGCTTGGCCAACGCCAATAACGCTAGTTTGTTTATGCTGTT
ACTGGCGGGATGGGCGAGCGTGCTCTATCAACGCACTCAGCGCAGCGATCTGCTGATTGGCACGCTCAGCGCTGGCCGTG
AGCATGCAGCGTTTGAGCGTTGCGTTGGCTTTTTTATTAATATCTTGCCCTTGCGCCTGCATTGCGCCGCCGAGCAAACG
TGGCTTGATCTATTGCAGCAAACCCGCATGGTTGCCTTACAAGCATACCAACACCAAGCCTTGCCATTCGAGCAGATTGT
GGCCAACGTGGCTCATGAGCGCAACAACCAACCGCAGATTCCGCTAATTCAAAGTTTGTTGGTGTTGCAAAACGCGCCCA
GTCAGCCCTTAGTTTTAGGTGCGCCAGCCCAAGCCCTAGCTACGCCAATTCAGGCCAGCAAAACCGATTTGGTGCTGTTG
GTGCAACCCGCTGCAACTGGCTATCAACTGACCCTAGAATATGCGAGCGAATTGTTCGTCGCTGAATCGATTGCAGCGTT
GGCCTCCGATTTCCAAGCGGTTTTAGGCCAAATGGCGCAGCATCCTACCAGCACACTTAGCGCTGTTCAGTTGGCTGGGC
ATTGGACGGCGGAGCACTATTCCAACAAATTACCCACGCTTCAGCCAATGGCCGCCCCGCCGCAAACAGCGCTAGAGCAA
ACCCTTGCCGATATGTGGCAAGAGGTCTTGGGCTTGTCAATTGATAATATTCATGCCGATTTCTTCCGCATGGGCGGCCA
TTCACTCAACGCCACCCAAGTTGTCTCGCGCATGCAACAGCTTTTACAGGTAACTACAAGTATTCGAATGTTGTTCGATT
ATCCAACGATTGCCCAATTAAGCCAGCATTTGCTGGCGAATCAAGCTCAGGCAGAGCGAATCAATAAAATTGCCACCGCA
CTGCAACAGATCAAAACCATGAGTGCCAGCACCAAACAGGCCTTGCAACAAAAGGCCGCAGGAAGGATAAGCCAACCATG
A

Upstream 100 bases:

>100_bases
CTGCCAAAATTGCCGAGTTGGTGCAAAAACTCCAGCAAGCTACACCTGAGCAGCGCCAACAAGCCTTAGCATCCAAGCGC
CAAGAACGGACGGTCGGCGA

Downstream 100 bases:

>100_bases
CCCAAACCTTGCCCCAAGGCTTTTCGACCGATGACCTTGAGTTGCTGGCCTATTTGCTTGAAGAAGCAGGCATTGATCAT
GCCGTGCCAAACCAAATTCA

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1146; Mature: 1145

Protein sequence:

>1146_residues
MSYSNITQLVTAQANQTPAAWAVQTPTGYGLTFADLEQQSSQAAAYLQHLGVQPASVVGICLRRTPQLIVWMLAILKAGA
TYLPLDPAYPTARLQFMLADAKALLVVSETSCQAALPLNTIEWVLIDQPWSRELAWREPFYHSAIPAYIIYTSGSTGQPK
GVLISHANALTFLAWAETTFSVAERAGILAATSINFDLSIFEIFLPLISGGTLVLVENLLDPALFHSQHPICLINSVPSA
VQTLLQHTALPSSVLTVNLAGEPLSLRLAQQLYQQPNIQRVFNLYGPTEATTYATYQLVERTASRPPAIGQPLTGTTCVI
LDAHYHPVAAKDVGELFIAGLGVAQGYLQRPDLTAERFLPNPWATTPGERMYKTGDLAHWNAANELCYLGRNDQQVKIRG
FRIELGEIEAQILRLAPLQAVVVQPITLVADDPQLTAYLVANQPIDCEALRASLAHHVPSYMLPSFWVQLAELPLTPNGK
LDRAALPCPDAPIKQPLQSSTEQRLAIIWREILGVEQLGRESNFLQLGGHSLNVMQVLKRIEQTWQLQLSITRLFEQPTL
AAWARLIDQQQQAFAQAEPQFYQRTTQLHQLSFGQQRLWFAEQLHPNTAYNVIHAWRIDALLDAVALEQSWLRLIERHEM
LRSSIQLIAGIPQQTIMLKPVWQLQSAPQASLEYLLRLLDRPFDLAQAPLLRVGLAQHHDHAIMLVVIHHSIIDAWSLGV
LWAELSQLYASFFENQPIQLPSQAYDYLDFVAWQRQQLDSACLAQLQTYWQTQLAQLDPLPALATDYPRSTHMQGLGISQ
TYQLDQQVIQALQGLANANNASLFMLLLAGWASVLYQRTQRSDLLIGTLSAGREHAAFERCVGFFINILPLRLHCAAEQT
WLDLLQQTRMVALQAYQHQALPFEQIVANVAHERNNQPQIPLIQSLLVLQNAPSQPLVLGAPAQALATPIQASKTDLVLL
VQPAATGYQLTLEYASELFVAESIAALASDFQAVLGQMAQHPTSTLSAVQLAGHWTAEHYSNKLPTLQPMAAPPQTALEQ
TLADMWQEVLGLSIDNIHADFFRMGGHSLNATQVVSRMQQLLQVTTSIRMLFDYPTIAQLSQHLLANQAQAERINKIATA
LQQIKTMSASTKQALQQKAAGRISQP

Sequences:

>Translated_1146_residues
MSYSNITQLVTAQANQTPAAWAVQTPTGYGLTFADLEQQSSQAAAYLQHLGVQPASVVGICLRRTPQLIVWMLAILKAGA
TYLPLDPAYPTARLQFMLADAKALLVVSETSCQAALPLNTIEWVLIDQPWSRELAWREPFYHSAIPAYIIYTSGSTGQPK
GVLISHANALTFLAWAETTFSVAERAGILAATSINFDLSIFEIFLPLISGGTLVLVENLLDPALFHSQHPICLINSVPSA
VQTLLQHTALPSSVLTVNLAGEPLSLRLAQQLYQQPNIQRVFNLYGPTEATTYATYQLVERTASRPPAIGQPLTGTTCVI
LDAHYHPVAAKDVGELFIAGLGVAQGYLQRPDLTAERFLPNPWATTPGERMYKTGDLAHWNAANELCYLGRNDQQVKIRG
FRIELGEIEAQILRLAPLQAVVVQPITLVADDPQLTAYLVANQPIDCEALRASLAHHVPSYMLPSFWVQLAELPLTPNGK
LDRAALPCPDAPIKQPLQSSTEQRLAIIWREILGVEQLGRESNFLQLGGHSLNVMQVLKRIEQTWQLQLSITRLFEQPTL
AAWARLIDQQQQAFAQAEPQFYQRTTQLHQLSFGQQRLWFAEQLHPNTAYNVIHAWRIDALLDAVALEQSWLRLIERHEM
LRSSIQLIAGIPQQTIMLKPVWQLQSAPQASLEYLLRLLDRPFDLAQAPLLRVGLAQHHDHAIMLVVIHHSIIDAWSLGV
LWAELSQLYASFFENQPIQLPSQAYDYLDFVAWQRQQLDSACLAQLQTYWQTQLAQLDPLPALATDYPRSTHMQGLGISQ
TYQLDQQVIQALQGLANANNASLFMLLLAGWASVLYQRTQRSDLLIGTLSAGREHAAFERCVGFFINILPLRLHCAAEQT
WLDLLQQTRMVALQAYQHQALPFEQIVANVAHERNNQPQIPLIQSLLVLQNAPSQPLVLGAPAQALATPIQASKTDLVLL
VQPAATGYQLTLEYASELFVAESIAALASDFQAVLGQMAQHPTSTLSAVQLAGHWTAEHYSNKLPTLQPMAAPPQTALEQ
TLADMWQEVLGLSIDNIHADFFRMGGHSLNATQVVSRMQQLLQVTTSIRMLFDYPTIAQLSQHLLANQAQAERINKIATA
LQQIKTMSASTKQALQQKAAGRISQP
>Mature_1145_residues
SYSNITQLVTAQANQTPAAWAVQTPTGYGLTFADLEQQSSQAAAYLQHLGVQPASVVGICLRRTPQLIVWMLAILKAGAT
YLPLDPAYPTARLQFMLADAKALLVVSETSCQAALPLNTIEWVLIDQPWSRELAWREPFYHSAIPAYIIYTSGSTGQPKG
VLISHANALTFLAWAETTFSVAERAGILAATSINFDLSIFEIFLPLISGGTLVLVENLLDPALFHSQHPICLINSVPSAV
QTLLQHTALPSSVLTVNLAGEPLSLRLAQQLYQQPNIQRVFNLYGPTEATTYATYQLVERTASRPPAIGQPLTGTTCVIL
DAHYHPVAAKDVGELFIAGLGVAQGYLQRPDLTAERFLPNPWATTPGERMYKTGDLAHWNAANELCYLGRNDQQVKIRGF
RIELGEIEAQILRLAPLQAVVVQPITLVADDPQLTAYLVANQPIDCEALRASLAHHVPSYMLPSFWVQLAELPLTPNGKL
DRAALPCPDAPIKQPLQSSTEQRLAIIWREILGVEQLGRESNFLQLGGHSLNVMQVLKRIEQTWQLQLSITRLFEQPTLA
AWARLIDQQQQAFAQAEPQFYQRTTQLHQLSFGQQRLWFAEQLHPNTAYNVIHAWRIDALLDAVALEQSWLRLIERHEML
RSSIQLIAGIPQQTIMLKPVWQLQSAPQASLEYLLRLLDRPFDLAQAPLLRVGLAQHHDHAIMLVVIHHSIIDAWSLGVL
WAELSQLYASFFENQPIQLPSQAYDYLDFVAWQRQQLDSACLAQLQTYWQTQLAQLDPLPALATDYPRSTHMQGLGISQT
YQLDQQVIQALQGLANANNASLFMLLLAGWASVLYQRTQRSDLLIGTLSAGREHAAFERCVGFFINILPLRLHCAAEQTW
LDLLQQTRMVALQAYQHQALPFEQIVANVAHERNNQPQIPLIQSLLVLQNAPSQPLVLGAPAQALATPIQASKTDLVLLV
QPAATGYQLTLEYASELFVAESIAALASDFQAVLGQMAQHPTSTLSAVQLAGHWTAEHYSNKLPTLQPMAAPPQTALEQT
LADMWQEVLGLSIDNIHADFFRMGGHSLNATQVVSRMQQLLQVTTSIRMLFDYPTIAQLSQHLLANQAQAERINKIATAL
QQIKTMSASTKQALQQKAAGRISQP

Specific function: Activates the 3rd to 6th amino acids (Ala, D-Leu, Ala and D-Val) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 4th (D-Leu) and the 6th (D-Val) amino acids [H

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=428, Percent_Identity=27.1028037383178, Blast_Score=117, Evalue=9e-26,
Organism=Escherichia coli, GI1786801, Length=604, Percent_Identity=34.7682119205298, Blast_Score=284, Evalue=2e-77,
Organism=Escherichia coli, GI1788107, Length=524, Percent_Identity=24.4274809160305, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI145693145, Length=512, Percent_Identity=22.0703125, Blast_Score=84, Evalue=6e-17,
Organism=Escherichia coli, GI1786810, Length=497, Percent_Identity=23.7424547283702, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17550940, Length=513, Percent_Identity=25.1461988304094, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17556356, Length=662, Percent_Identity=24.3202416918429, Blast_Score=133, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6319591, Length=688, Percent_Identity=25.5813953488372, Blast_Score=187, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6319699, Length=539, Percent_Identity=22.4489795918367, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648676, Length=563, Percent_Identity=32.3268206039076, Blast_Score=201, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 127076; Mature: 126944

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSNITQLVTAQANQTPAAWAVQTPTGYGLTFADLEQQSSQAAAYLQHLGVQPASVVGI
CCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
CLRRTPQLIVWMLAILKAGATYLPLDPAYPTARLQFMLADAKALLVVSETSCQAALPLNT
HHHCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEEECCEEEEEEECCCCCEECCCCC
IEWVLIDQPWSRELAWREPFYHSAIPAYIIYTSGSTGQPKGVLISHANALTFLAWAETTF
EEEEEECCCCCCCCCCCCCCHHCCCCEEEEEECCCCCCCCCEEEECCCHHEEEHHHHHHH
SVAERAGILAATSINFDLSIFEIFLPLISGGTLVLVENLLDPALFHSQHPICLINSVPSA
HHHHHCCEEEEEECCCCHHHHHHHHHHHCCCHHEEHHHHHCHHHHCCCCCEEEECCCHHH
VQTLLQHTALPSSVLTVNLAGEPLSLRLAQQLYQQPNIQRVFNLYGPTEATTYATYQLVE
HHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHH
RTASRPPAIGQPLTGTTCVILDAHYHPVAAKDVGELFIAGLGVAQGYLQRPDLTAERFLP
HHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCC
NPWATTPGERMYKTGDLAHWNAANELCYLGRNDQQVKIRGFRIELGEIEAQILRLAPLQA
CCCCCCCCHHHCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEEEHHHHHHHHHHHHHHHH
VVVQPITLVADDPQLTAYLVANQPIDCEALRASLAHHVPSYMLPSFWVQLAELPLTPNGK
HHHCCEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCC
LDRAALPCPDAPIKQPLQSSTEQRLAIIWREILGVEQLGRESNFLQLGGHSLNVMQVLKR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEECCCCCHHHHHHHH
IEQTWQLQLSITRLFEQPTLAAWARLIDQQQQAFAQAEPQFYQRTTQLHQLSFGQQRLWF
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHH
AEQLHPNTAYNVIHAWRIDALLDAVALEQSWLRLIERHEMLRSSIQLIAGIPQQTIMLKP
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECC
VWQLQSAPQASLEYLLRLLDRPFDLAQAPLLRVGLAQHHDHAIMLVVIHHSIIDAWSLGV
HHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHH
LWAELSQLYASFFENQPIQLPSQAYDYLDFVAWQRQQLDSACLAQLQTYWQTQLAQLDPL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PALATDYPRSTHMQGLGISQTYQLDQQVIQALQGLANANNASLFMLLLAGWASVLYQRTQ
CCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
RSDLLIGTLSAGREHAAFERCVGFFINILPLRLHCAAEQTWLDLLQQTRMVALQAYQHQA
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LPFEQIVANVAHERNNQPQIPLIQSLLVLQNAPSQPLVLGAPAQALATPIQASKTDLVLL
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHCCCCCCCCCEEEE
VQPAATGYQLTLEYASELFVAESIAALASDFQAVLGQMAQHPTSTLSAVQLAGHWTAEHY
EECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHH
SNKLPTLQPMAAPPQTALEQTLADMWQEVLGLSIDNIHADFFRMGGHSLNATQVVSRMQQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
LLQVTTSIRMLFDYPTIAQLSQHLLANQAQAERINKIATALQQIKTMSASTKQALQQKAA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRISQP
CCCCCC
>Mature Secondary Structure 
SYSNITQLVTAQANQTPAAWAVQTPTGYGLTFADLEQQSSQAAAYLQHLGVQPASVVGI
CHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
CLRRTPQLIVWMLAILKAGATYLPLDPAYPTARLQFMLADAKALLVVSETSCQAALPLNT
HHHCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEEECCEEEEEEECCCCCEECCCCC
IEWVLIDQPWSRELAWREPFYHSAIPAYIIYTSGSTGQPKGVLISHANALTFLAWAETTF
EEEEEECCCCCCCCCCCCCCHHCCCCEEEEEECCCCCCCCCEEEECCCHHEEEHHHHHHH
SVAERAGILAATSINFDLSIFEIFLPLISGGTLVLVENLLDPALFHSQHPICLINSVPSA
HHHHHCCEEEEEECCCCHHHHHHHHHHHCCCHHEEHHHHHCHHHHCCCCCEEEECCCHHH
VQTLLQHTALPSSVLTVNLAGEPLSLRLAQQLYQQPNIQRVFNLYGPTEATTYATYQLVE
HHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHH
RTASRPPAIGQPLTGTTCVILDAHYHPVAAKDVGELFIAGLGVAQGYLQRPDLTAERFLP
HHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCC
NPWATTPGERMYKTGDLAHWNAANELCYLGRNDQQVKIRGFRIELGEIEAQILRLAPLQA
CCCCCCCCHHHCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEEEHHHHHHHHHHHHHHHH
VVVQPITLVADDPQLTAYLVANQPIDCEALRASLAHHVPSYMLPSFWVQLAELPLTPNGK
HHHCCEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCC
LDRAALPCPDAPIKQPLQSSTEQRLAIIWREILGVEQLGRESNFLQLGGHSLNVMQVLKR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEECCCCCHHHHHHHH
IEQTWQLQLSITRLFEQPTLAAWARLIDQQQQAFAQAEPQFYQRTTQLHQLSFGQQRLWF
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHH
AEQLHPNTAYNVIHAWRIDALLDAVALEQSWLRLIERHEMLRSSIQLIAGIPQQTIMLKP
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECC
VWQLQSAPQASLEYLLRLLDRPFDLAQAPLLRVGLAQHHDHAIMLVVIHHSIIDAWSLGV
HHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHH
LWAELSQLYASFFENQPIQLPSQAYDYLDFVAWQRQQLDSACLAQLQTYWQTQLAQLDPL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PALATDYPRSTHMQGLGISQTYQLDQQVIQALQGLANANNASLFMLLLAGWASVLYQRTQ
CCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
RSDLLIGTLSAGREHAAFERCVGFFINILPLRLHCAAEQTWLDLLQQTRMVALQAYQHQA
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LPFEQIVANVAHERNNQPQIPLIQSLLVLQNAPSQPLVLGAPAQALATPIQASKTDLVLL
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHCCCCCCCCCEEEE
VQPAATGYQLTLEYASELFVAESIAALASDFQAVLGQMAQHPTSTLSAVQLAGHWTAEHY
EECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHH
SNKLPTLQPMAAPPQTALEQTLADMWQEVLGLSIDNIHADFFRMGGHSLNATQVVSRMQQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
LLQVTTSIRMLFDYPTIAQLSQHLLANQAQAERINKIATALQQIKTMSASTKQALQQKAA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRISQP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA