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The map label for this gene is lgrD [H]

Identifier: 159898610

GI number: 159898610

Start: 2602175

End: 2606266

Strand: Reverse

Name: lgrD [H]

Synonym: Haur_2089

Alternate gene names: 159898610

Gene position: 2606266-2602175 (Counterclockwise)

Preceding gene: 159898611

Following gene: 159898609

Centisome position: 41.07

GC content: 51.86

Gene sequence:

>4092_bases
ATGACCCAAACCTTGCCCCAAGGCTTTTCGACCGATGACCTTGAGTTGCTGGCCTATTTGCTTGAAGAAGCAGGCATTGA
TCATGCCGTGCCAAACCAAATTCAGCCTCGTCCAGCCAACCAGCCAGTTCCACTGTCGTTTGCCCAAGAACGCTTGTGGT
TTATCGACCAGCTAGAACCTGGCAATCCAGCCTATAATATTTTGTTTGCGGTGCAGATTGACGGCCCGTTGCATGTCGCA
TACTTGCAGCAGAGCTTTGATGCGGTGATTGCCCGCCACGAGAGCCTGCGTACCAGCTTTCCAGTGCTCAACGATCAGCC
GATTCAGGCGATTGCTGAAAAACATGATTTTGACTTAACAATCGTCGATCTCCGCTATTTAGCAGCAATTGAACAAGCAT
CAACAATTGAACAACTATCAATTGAACAACGCTCAATTATCGAACAGCAATTACTGATCGATAGTGCCCATCGTTTTGAT
TTGGCGCAAGGCCCATTGCTGTATGGTCGTTTGCTCTGGCTGGCCGAGCAGCAATATGTGCTGATTCTCAACTTGCACCA
TGCGATTTTTGATGGCTGGTCGTTGGCAATTTTTATTGAGGAATTGCGCCATTGCTATAGCGCCTTGCTTGCAGGTCAAG
CGCTCGATTTAACCCCAGCAGCGTTGCAATATGCCGATTTTAGTTATTGGCAGCGTGAATATTTGCAAGGCGAGGTTTTG
GCCGCGCAATTAGCCTTTTGGCAAAACCAATTTGCTGGACGTTTGCCCACCTTGGCCTTACCAACCGATCGACCACGCCC
AAAACACGAGACTGGTCGTGGCGCAGCCTTGCCATTTCGTGTTGATCAGGTATTAACGGAGCAGTTGCAACACCTCGCCC
AAAACGAACATGCCACGATGTTTATGCTGTTATTGGCGGCATTTCAGCTGATGCTGGCTCGCTATAGCCAACAGCAAGAG
TTTGTGGTTGGCTCGCCAATTGCCAATCGTGATCGGGTTGAAATTGAGCATTTGATCGGCTTTTTCGTCAATATGCTGCT
GCTGCGTTGTGATGTTCAGCCGCAGCTGAGCTTTCGCGAATTTCTGGCGCAAGTGCGCGAAACGACGCTCGAAGCCTATG
CCCACCAAGATTTGCCCTTTGAGCAGTTGGTCGAGGTGCTTCAGCCCGACCGTGGCGCAGGCTATGGTTCGTTGTTTCAG
GTGATGTTTGTGCTGCAAAATACGCCTAAGGTCAACTATGAGATCGCCGATTTGCAGCTGAGCTTTCTCGATACCGAGGC
GCATAGTACCAAATATGACCTGACCATGACCTTGACTGAAACCGCAACTGGGCTGGAAGGTTGGTTTGAATACAACACCG
ATTTGTACGATCAGGCCACGATTCAGCGCATGCTTGGGCATTATCAACAAGTATTACGGGTGGTTGGCGAAGCGCCTGAT
CAAGCACTTAATGCGATTAGCGTATTTGATGAGCAAGCCCAAACGGCTTTATTCAAGCTAAGCAATCAAACTCAGCACGA
TTTTGGCCCTGCTGATTTCTTAGAACGCTTTGCCAATCAAGTGGCAGCGACACCCAACGCGATTGCGGTGCGCGATGCCC
ATCAGCAGTATTCGTATCAGGCTTTGCAGCAACGAGCTATGGCTTTGGCGGCCCAACTGCAACAGCATGGCGTTAGGCAA
GAAACCCTCGTGCCAATTTTGTTGCCGCGTACCAGCGATTTTGTGGTTGCGGTTTTGGGTGTTTTTTACGCTGGGGCAGC
CTATTTACCGCTTGACCCTGCGTGGCCAGCCCAGCGTAGCGCCCAGATTTTGCAGGGATTGGCGATTCCTGCCTTGATTT
GCGAACCCGATTTAGCCCGTTGGTTTGCTAAGCATGTTCAGCCGTTGTTTAGGCTTCACAATCAGCCGCAGTTAATCGAA
CAATGGAATGATGCAGCAACCAAGCTTGTTGTAAGCCAAACCCATCCGCAGCAATTGGCCTATACCCTGTTTACCTCTGG
CTCAACTGGCACACCCAAAGGAGTGATGATCGATCAGGCTGGGATGCTCAACCATCTGTTGGTGATGAATCAGGTGCTGG
AAATCCAAGCCCATGATGTGGTGGCCCAAACCGCTTCGCAATGCTTCGATATCTCAGTGTGGCAGATGCTGTCGGGCTTG
TTGGTTGGCGCAACGGTGGCAATCATTGATGATCAGACGATGCGTGACCCGTTGGCCTTAGCCCAAACTCTGGCTGAACA
GCAAGTCACAACTTTCGAGCCGGTGCCAAGCCTGTTGCAAGCCTTGCTTGAAACATTGCAAACCCCTGCTGAACAAGCCT
TATTGCACCGCTTGCGCTGGGTTTTGCCAACCGGCGAGGCCTTGCAACCAGTTCAGGCCCGTCAATGGTTTGCCACCTAT
CCGCAGATTCCGTTGCTGAATGCGTATGGGCCTGCCGAATGTGCCGACGATGTAACCCTGCAACGGCTTGATTCTGCTCC
GACCGAAGGCCATAGCACCATGCCAATCGGCAAGCCTGTCGCCAATATGCAGGTGTTTGTGCTTGATCCAAACTGGCAAT
TGTTGCCATTGGGCGCAGTCGGCGAATTGTATATCGGTGGAGTTGGGGTTGGTCGGGGCTATTTGAATGATCCAGCCCGC
ACTGCCAGCGCCTTCGTACCCAACCCATTTGCTGATAATGGCAGTCGGCTCTATCGTACTGGCGATTTGGTGCGCCAAAC
TGCTGATGGGGCTTTGCACTTCATTGGTCGCGCTGATCAGCAAGTTAAAGTGCGCGGCTATCGGATTGAACTAGGCGAGA
TCGAGGCGGTCTTGGCGGAATTGAGCTGGTTGCGCGAGGCGGCGGTGCACCCTTGGCAGCAACAATTAGTTGCCTATCTG
GTTCCGGTTTCCGATACTCCTGATTTGATCAGCCTTGTGCAGCCTGCGCTCCAACAGCGATTGCCCAGCTATATGCTGCC
AAACCAATATCTGGTTTTAGATCAATTGCCGCGTAACCGTAATGGCAAGCTTGATCGTCAACAACTGCCAGCGCCGAATC
CTGCCAACCTTGGCTTTCAAACACCGCTGGTTGTGCCACGTACCCAGCACGAGGCCGAACTCGCGGCGATTTGGGCTGAC
GTACTTCAACTTGACGTAATCAGTATTGATGCCAATTTCTTCAGCAGCGGCGGCCACTCGCTCTTAGCAACGCGGGTGAT
GCTACGCACACGCCAGCATTATGGCCGTGATTTACCATTGCGCATGATTTTTGAAGCACCAACTATTCGTGAATTTGCTG
CCTTATTGGAACAGCAACAAGCAGTGTCAGCGCTCCCTAACCTACTCGTGCCTATTAAACCCCAAGGCTCACGCACGCCA
CTGGTGTGTGTCCATGCAATTGCGGGCACGGTTGGCTGTTATAGCGAACTAGCAATTGCACTTAATCCTGAACAACCCGT
GTATGCCTTGCAAGCACCTGGCATTGACGGCGGCACAACCCATGCCAAGGTTGAAGCAATTGCCCAAGACTATTGCCAAG
CATTGCGACAACTGCAACCTCAGGGGCCATATCGTTTGGCTGGTTGGTCATTTGGAGGTTTGGTTGCGCTTGAAATGGCG
CGACAACTGCAACTTGCTGGCGAGCAGGTATCTATGCTCAGTTTGATCGATAGCTTTCTGGCCGAGCCAACGCCTGATCC
ATTCCCATTGATTCAGAGCTTCGCCGCCGATCTGTTTGCTGATGTTGATCCATTGGCGGCGCAACAGATCGATTGGCCCG
CGATTGTAGTGCTGCCTGCTGAGCAACAATTGGCGGCGCTCTATCAACAAGCCCAACAGGCTGGCCTAATTGATCGTGAT
CTGCCGTTCGATCTGGCACAACGCTTATACGCGGTTTTTACCAGCCATGCCCACGCCATACAAGCCTATCAGCCCGCTAT
ATATCTTGGGGAAGCTCAATTGCTGCAAGCTCAAGCCAACCCAGCAGCAGCTCGCCGCTGGCAAGCAGTCATTCCAAATC
TGCACATTCAGGTAATCGGCGGCGATCATATCAGCATTCTGCGGCAGCCCCATGTGCATGGTTTAGCAAATGCCATAGAG
CAGAGAACATAG

Upstream 100 bases:

>100_bases
GAATCAATAAAATTGCCACCGCACTGCAACAGATCAAAACCATGAGTGCCAGCACCAAACAGGCCTTGCAACAAAAGGCC
GCAGGAAGGATAAGCCAACC

Downstream 100 bases:

>100_bases
GGTCGGAAATGCGCAATCGAGGTTTTAACGCAGAAACGCAGAGCAATAATGGCTATGGGCTATCGGCACAATTGTTGGTA
TGTTCAAGCAATCTTCTATA

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-Leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent glycine adenylase; GlyA; Glycine activase; Linear gramicidin--PCP reductase [H]

Number of amino acids: Translated: 1363; Mature: 1362

Protein sequence:

>1363_residues
MTQTLPQGFSTDDLELLAYLLEEAGIDHAVPNQIQPRPANQPVPLSFAQERLWFIDQLEPGNPAYNILFAVQIDGPLHVA
YLQQSFDAVIARHESLRTSFPVLNDQPIQAIAEKHDFDLTIVDLRYLAAIEQASTIEQLSIEQRSIIEQQLLIDSAHRFD
LAQGPLLYGRLLWLAEQQYVLILNLHHAIFDGWSLAIFIEELRHCYSALLAGQALDLTPAALQYADFSYWQREYLQGEVL
AAQLAFWQNQFAGRLPTLALPTDRPRPKHETGRGAALPFRVDQVLTEQLQHLAQNEHATMFMLLLAAFQLMLARYSQQQE
FVVGSPIANRDRVEIEHLIGFFVNMLLLRCDVQPQLSFREFLAQVRETTLEAYAHQDLPFEQLVEVLQPDRGAGYGSLFQ
VMFVLQNTPKVNYEIADLQLSFLDTEAHSTKYDLTMTLTETATGLEGWFEYNTDLYDQATIQRMLGHYQQVLRVVGEAPD
QALNAISVFDEQAQTALFKLSNQTQHDFGPADFLERFANQVAATPNAIAVRDAHQQYSYQALQQRAMALAAQLQQHGVRQ
ETLVPILLPRTSDFVVAVLGVFYAGAAYLPLDPAWPAQRSAQILQGLAIPALICEPDLARWFAKHVQPLFRLHNQPQLIE
QWNDAATKLVVSQTHPQQLAYTLFTSGSTGTPKGVMIDQAGMLNHLLVMNQVLEIQAHDVVAQTASQCFDISVWQMLSGL
LVGATVAIIDDQTMRDPLALAQTLAEQQVTTFEPVPSLLQALLETLQTPAEQALLHRLRWVLPTGEALQPVQARQWFATY
PQIPLLNAYGPAECADDVTLQRLDSAPTEGHSTMPIGKPVANMQVFVLDPNWQLLPLGAVGELYIGGVGVGRGYLNDPAR
TASAFVPNPFADNGSRLYRTGDLVRQTADGALHFIGRADQQVKVRGYRIELGEIEAVLAELSWLREAAVHPWQQQLVAYL
VPVSDTPDLISLVQPALQQRLPSYMLPNQYLVLDQLPRNRNGKLDRQQLPAPNPANLGFQTPLVVPRTQHEAELAAIWAD
VLQLDVISIDANFFSSGGHSLLATRVMLRTRQHYGRDLPLRMIFEAPTIREFAALLEQQQAVSALPNLLVPIKPQGSRTP
LVCVHAIAGTVGCYSELAIALNPEQPVYALQAPGIDGGTTHAKVEAIAQDYCQALRQLQPQGPYRLAGWSFGGLVALEMA
RQLQLAGEQVSMLSLIDSFLAEPTPDPFPLIQSFAADLFADVDPLAAQQIDWPAIVVLPAEQQLAALYQQAQQAGLIDRD
LPFDLAQRLYAVFTSHAHAIQAYQPAIYLGEAQLLQAQANPAAARRWQAVIPNLHIQVIGGDHISILRQPHVHGLANAIE
QRT

Sequences:

>Translated_1363_residues
MTQTLPQGFSTDDLELLAYLLEEAGIDHAVPNQIQPRPANQPVPLSFAQERLWFIDQLEPGNPAYNILFAVQIDGPLHVA
YLQQSFDAVIARHESLRTSFPVLNDQPIQAIAEKHDFDLTIVDLRYLAAIEQASTIEQLSIEQRSIIEQQLLIDSAHRFD
LAQGPLLYGRLLWLAEQQYVLILNLHHAIFDGWSLAIFIEELRHCYSALLAGQALDLTPAALQYADFSYWQREYLQGEVL
AAQLAFWQNQFAGRLPTLALPTDRPRPKHETGRGAALPFRVDQVLTEQLQHLAQNEHATMFMLLLAAFQLMLARYSQQQE
FVVGSPIANRDRVEIEHLIGFFVNMLLLRCDVQPQLSFREFLAQVRETTLEAYAHQDLPFEQLVEVLQPDRGAGYGSLFQ
VMFVLQNTPKVNYEIADLQLSFLDTEAHSTKYDLTMTLTETATGLEGWFEYNTDLYDQATIQRMLGHYQQVLRVVGEAPD
QALNAISVFDEQAQTALFKLSNQTQHDFGPADFLERFANQVAATPNAIAVRDAHQQYSYQALQQRAMALAAQLQQHGVRQ
ETLVPILLPRTSDFVVAVLGVFYAGAAYLPLDPAWPAQRSAQILQGLAIPALICEPDLARWFAKHVQPLFRLHNQPQLIE
QWNDAATKLVVSQTHPQQLAYTLFTSGSTGTPKGVMIDQAGMLNHLLVMNQVLEIQAHDVVAQTASQCFDISVWQMLSGL
LVGATVAIIDDQTMRDPLALAQTLAEQQVTTFEPVPSLLQALLETLQTPAEQALLHRLRWVLPTGEALQPVQARQWFATY
PQIPLLNAYGPAECADDVTLQRLDSAPTEGHSTMPIGKPVANMQVFVLDPNWQLLPLGAVGELYIGGVGVGRGYLNDPAR
TASAFVPNPFADNGSRLYRTGDLVRQTADGALHFIGRADQQVKVRGYRIELGEIEAVLAELSWLREAAVHPWQQQLVAYL
VPVSDTPDLISLVQPALQQRLPSYMLPNQYLVLDQLPRNRNGKLDRQQLPAPNPANLGFQTPLVVPRTQHEAELAAIWAD
VLQLDVISIDANFFSSGGHSLLATRVMLRTRQHYGRDLPLRMIFEAPTIREFAALLEQQQAVSALPNLLVPIKPQGSRTP
LVCVHAIAGTVGCYSELAIALNPEQPVYALQAPGIDGGTTHAKVEAIAQDYCQALRQLQPQGPYRLAGWSFGGLVALEMA
RQLQLAGEQVSMLSLIDSFLAEPTPDPFPLIQSFAADLFADVDPLAAQQIDWPAIVVLPAEQQLAALYQQAQQAGLIDRD
LPFDLAQRLYAVFTSHAHAIQAYQPAIYLGEAQLLQAQANPAAARRWQAVIPNLHIQVIGGDHISILRQPHVHGLANAIE
QRT
>Mature_1362_residues
TQTLPQGFSTDDLELLAYLLEEAGIDHAVPNQIQPRPANQPVPLSFAQERLWFIDQLEPGNPAYNILFAVQIDGPLHVAY
LQQSFDAVIARHESLRTSFPVLNDQPIQAIAEKHDFDLTIVDLRYLAAIEQASTIEQLSIEQRSIIEQQLLIDSAHRFDL
AQGPLLYGRLLWLAEQQYVLILNLHHAIFDGWSLAIFIEELRHCYSALLAGQALDLTPAALQYADFSYWQREYLQGEVLA
AQLAFWQNQFAGRLPTLALPTDRPRPKHETGRGAALPFRVDQVLTEQLQHLAQNEHATMFMLLLAAFQLMLARYSQQQEF
VVGSPIANRDRVEIEHLIGFFVNMLLLRCDVQPQLSFREFLAQVRETTLEAYAHQDLPFEQLVEVLQPDRGAGYGSLFQV
MFVLQNTPKVNYEIADLQLSFLDTEAHSTKYDLTMTLTETATGLEGWFEYNTDLYDQATIQRMLGHYQQVLRVVGEAPDQ
ALNAISVFDEQAQTALFKLSNQTQHDFGPADFLERFANQVAATPNAIAVRDAHQQYSYQALQQRAMALAAQLQQHGVRQE
TLVPILLPRTSDFVVAVLGVFYAGAAYLPLDPAWPAQRSAQILQGLAIPALICEPDLARWFAKHVQPLFRLHNQPQLIEQ
WNDAATKLVVSQTHPQQLAYTLFTSGSTGTPKGVMIDQAGMLNHLLVMNQVLEIQAHDVVAQTASQCFDISVWQMLSGLL
VGATVAIIDDQTMRDPLALAQTLAEQQVTTFEPVPSLLQALLETLQTPAEQALLHRLRWVLPTGEALQPVQARQWFATYP
QIPLLNAYGPAECADDVTLQRLDSAPTEGHSTMPIGKPVANMQVFVLDPNWQLLPLGAVGELYIGGVGVGRGYLNDPART
ASAFVPNPFADNGSRLYRTGDLVRQTADGALHFIGRADQQVKVRGYRIELGEIEAVLAELSWLREAAVHPWQQQLVAYLV
PVSDTPDLISLVQPALQQRLPSYMLPNQYLVLDQLPRNRNGKLDRQQLPAPNPANLGFQTPLVVPRTQHEAELAAIWADV
LQLDVISIDANFFSSGGHSLLATRVMLRTRQHYGRDLPLRMIFEAPTIREFAALLEQQQAVSALPNLLVPIKPQGSRTPL
VCVHAIAGTVGCYSELAIALNPEQPVYALQAPGIDGGTTHAKVEAIAQDYCQALRQLQPQGPYRLAGWSFGGLVALEMAR
QLQLAGEQVSMLSLIDSFLAEPTPDPFPLIQSFAADLFADVDPLAAQQIDWPAIVVLPAEQQLAALYQQAQQAGLIDRDL
PFDLAQRLYAVFTSHAHAIQAYQPAIYLGEAQLLQAQANPAAARRWQAVIPNLHIQVIGGDHISILRQPHVHGLANAIEQ
RT

Specific function: Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=629, Percent_Identity=23.5294117647059, Blast_Score=133, Evalue=2e-30,
Organism=Homo sapiens, GI42544132, Length=394, Percent_Identity=24.3654822335025, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI38505220, Length=387, Percent_Identity=24.8062015503876, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI122937307, Length=374, Percent_Identity=25.668449197861, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI58082049, Length=524, Percent_Identity=23.2824427480916, Blast_Score=76, Evalue=2e-13,
Organism=Homo sapiens, GI157311624, Length=514, Percent_Identity=23.9299610894942, Blast_Score=76, Evalue=3e-13,
Organism=Homo sapiens, GI157311622, Length=514, Percent_Identity=23.9299610894942, Blast_Score=76, Evalue=3e-13,
Organism=Homo sapiens, GI13375727, Length=534, Percent_Identity=21.5355805243446, Blast_Score=75, Evalue=6e-13,
Organism=Homo sapiens, GI115511026, Length=496, Percent_Identity=23.1854838709677, Blast_Score=73, Evalue=2e-12,
Organism=Homo sapiens, GI187761345, Length=534, Percent_Identity=21.3483146067416, Blast_Score=70, Evalue=2e-11,
Organism=Homo sapiens, GI187761343, Length=534, Percent_Identity=21.3483146067416, Blast_Score=70, Evalue=2e-11,
Organism=Homo sapiens, GI41872631, Length=305, Percent_Identity=29.5081967213115, Blast_Score=69, Evalue=5e-11,
Organism=Escherichia coli, GI1786801, Length=1223, Percent_Identity=30.1717089125102, Blast_Score=424, Evalue=1e-119,
Organism=Escherichia coli, GI145693145, Length=555, Percent_Identity=25.5855855855856, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI1788107, Length=552, Percent_Identity=24.0942028985507, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1786810, Length=519, Percent_Identity=26.0115606936416, Blast_Score=97, Evalue=7e-21,
Organism=Escherichia coli, GI1790505, Length=544, Percent_Identity=22.9779411764706, Blast_Score=91, Evalue=7e-19,
Organism=Escherichia coli, GI221142682, Length=517, Percent_Identity=22.0502901353965, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17550940, Length=1216, Percent_Identity=21.5460526315789, Blast_Score=191, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17556356, Length=1081, Percent_Identity=22.6641998149861, Blast_Score=154, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71983001, Length=606, Percent_Identity=21.7821782178218, Blast_Score=70, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71982997, Length=606, Percent_Identity=21.7821782178218, Blast_Score=70, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=969, Percent_Identity=24.3550051599587, Blast_Score=233, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6319264, Length=378, Percent_Identity=25.3968253968254, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319699, Length=371, Percent_Identity=23.4501347708895, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648676, Length=525, Percent_Identity=30.2857142857143, Blast_Score=189, Evalue=1e-47,
Organism=Drosophila melanogaster, GI62472339, Length=574, Percent_Identity=22.1254355400697, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24667955, Length=574, Percent_Identity=22.1254355400697, Blast_Score=92, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24667959, Length=415, Percent_Identity=24.8192771084337, Blast_Score=88, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24582852, Length=560, Percent_Identity=23.9285714285714, Blast_Score=83, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013120
- InterPro:   IPR016040
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR010080 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF07993 NAD_binding_4; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 151516; Mature: 151385

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTLPQGFSTDDLELLAYLLEEAGIDHAVPNQIQPRPANQPVPLSFAQERLWFIDQLEP
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
GNPAYNILFAVQIDGPLHVAYLQQSFDAVIARHESLRTSFPVLNDQPIQAIAEKHDFDLT
CCCCEEEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEE
IVDLRYLAAIEQASTIEQLSIEQRSIIEQQLLIDSAHRFDLAQGPLLYGRLLWLAEQQYV
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEE
LILNLHHAIFDGWSLAIFIEELRHCYSALLAGQALDLTPAALQYADFSYWQREYLQGEVL
EEEEEHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAQLAFWQNQFAGRLPTLALPTDRPRPKHETGRGAALPFRVDQVLTEQLQHLAQNEHATM
HHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHH
FMLLLAAFQLMLARYSQQQEFVVGSPIANRDRVEIEHLIGFFVNMLLLRCDVQPQLSFRE
HHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
FLAQVRETTLEAYAHQDLPFEQLVEVLQPDRGAGYGSLFQVMFVLQNTPKVNYEIADLQL
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEE
SFLDTEAHSTKYDLTMTLTETATGLEGWFEYNTDLYDQATIQRMLGHYQQVLRVVGEAPD
EEEECCCCCCEEEEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCH
QALNAISVFDEQAQTALFKLSNQTQHDFGPADFLERFANQVAATPNAIAVRDAHQQYSYQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHH
ALQQRAMALAAQLQQHGVRQETLVPILLPRTSDFVVAVLGVFYAGAAYLPLDPAWPAQRS
HHHHHHHHHHHHHHHCCCCHHCCCEEEECCCCHHHHHHHHHHHCCCEECCCCCCCCCHHH
AQILQGLAIPALICEPDLARWFAKHVQPLFRLHNQPQLIEQWNDAATKLVVSQTHPQQLA
HHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEECCCHHHEE
YTLFTSGSTGTPKGVMIDQAGMLNHLLVMNQVLEIQAHDVVAQTASQCFDISVWQMLSGL
EEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LVGATVAIIDDQTMRDPLALAQTLAEQQVTTFEPVPSLLQALLETLQTPAEQALLHRLRW
HHHCEEEEECCCHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
VLPTGEALQPVQARQWFATYPQIPLLNAYGPAECADDVTLQRLDSAPTEGHSTMPIGKPV
HCCCCHHCCCHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
ANMQVFVLDPNWQLLPLGAVGELYIGGVGVGRGYLNDPARTASAFVPNPFADNGSRLYRT
CCCEEEEECCCCEEEECCCCCCEEECCEEECCCCCCCCHHHHHCCCCCCCCCCCCEEEEH
GDLVRQTADGALHFIGRADQQVKVRGYRIELGEIEAVLAELSWLREAAVHPWQQQLVAYL
HHHHHHHHCCHHHHHCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHE
VPVSDTPDLISLVQPALQQRLPSYMLPNQYLVLDQLPRNRNGKLDRQQLPAPNPANLGFQ
ECCCCCHHHHHHHHHHHHHHCCHHCCCCCEEEEECCCCCCCCCCCHHHCCCCCCCCCCCC
TPLVVPRTQHEAELAAIWADVLQLDVISIDANFFSSGGHSLLATRVMLRTRQHYGRDLPL
CCEECCCCCHHHHHHHHHHHHHHHEEEEEECHHHCCCCHHHHHHHHHHHHHHHHCCCCCE
RMIFEAPTIREFAALLEQQQAVSALPNLLVPIKPQGSRTPLVCVHAIAGTVGCYSELAIA
EEEECCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCEEHHHHHHHHHHHHHCEEEE
LNPEQPVYALQAPGIDGGTTHAKVEAIAQDYCQALRQLQPQGPYRLAGWSFGGLVALEMA
ECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
RQLQLAGEQVSMLSLIDSFLAEPTPDPFPLIQSFAADLFADVDPLAAQQIDWPAIVVLPA
HHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEECC
EQQLAALYQQAQQAGLIDRDLPFDLAQRLYAVFTSHAHAIQAYQPAIYLGEAQLLQAQAN
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHCCC
PAAARRWQAVIPNLHIQVIGGDHISILRQPHVHGLANAIEQRT
HHHHHHHHHHCCCCEEEEECCCCEEECCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TQTLPQGFSTDDLELLAYLLEEAGIDHAVPNQIQPRPANQPVPLSFAQERLWFIDQLEP
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
GNPAYNILFAVQIDGPLHVAYLQQSFDAVIARHESLRTSFPVLNDQPIQAIAEKHDFDLT
CCCCEEEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEE
IVDLRYLAAIEQASTIEQLSIEQRSIIEQQLLIDSAHRFDLAQGPLLYGRLLWLAEQQYV
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEE
LILNLHHAIFDGWSLAIFIEELRHCYSALLAGQALDLTPAALQYADFSYWQREYLQGEVL
EEEEEHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAQLAFWQNQFAGRLPTLALPTDRPRPKHETGRGAALPFRVDQVLTEQLQHLAQNEHATM
HHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHH
FMLLLAAFQLMLARYSQQQEFVVGSPIANRDRVEIEHLIGFFVNMLLLRCDVQPQLSFRE
HHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
FLAQVRETTLEAYAHQDLPFEQLVEVLQPDRGAGYGSLFQVMFVLQNTPKVNYEIADLQL
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEE
SFLDTEAHSTKYDLTMTLTETATGLEGWFEYNTDLYDQATIQRMLGHYQQVLRVVGEAPD
EEEECCCCCCEEEEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCH
QALNAISVFDEQAQTALFKLSNQTQHDFGPADFLERFANQVAATPNAIAVRDAHQQYSYQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHH
ALQQRAMALAAQLQQHGVRQETLVPILLPRTSDFVVAVLGVFYAGAAYLPLDPAWPAQRS
HHHHHHHHHHHHHHHCCCCHHCCCEEEECCCCHHHHHHHHHHHCCCEECCCCCCCCCHHH
AQILQGLAIPALICEPDLARWFAKHVQPLFRLHNQPQLIEQWNDAATKLVVSQTHPQQLA
HHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEECCCHHHEE
YTLFTSGSTGTPKGVMIDQAGMLNHLLVMNQVLEIQAHDVVAQTASQCFDISVWQMLSGL
EEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LVGATVAIIDDQTMRDPLALAQTLAEQQVTTFEPVPSLLQALLETLQTPAEQALLHRLRW
HHHCEEEEECCCHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
VLPTGEALQPVQARQWFATYPQIPLLNAYGPAECADDVTLQRLDSAPTEGHSTMPIGKPV
HCCCCHHCCCHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
ANMQVFVLDPNWQLLPLGAVGELYIGGVGVGRGYLNDPARTASAFVPNPFADNGSRLYRT
CCCEEEEECCCCEEEECCCCCCEEECCEEECCCCCCCCHHHHHCCCCCCCCCCCCEEEEH
GDLVRQTADGALHFIGRADQQVKVRGYRIELGEIEAVLAELSWLREAAVHPWQQQLVAYL
HHHHHHHHCCHHHHHCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHE
VPVSDTPDLISLVQPALQQRLPSYMLPNQYLVLDQLPRNRNGKLDRQQLPAPNPANLGFQ
ECCCCCHHHHHHHHHHHHHHCCHHCCCCCEEEEECCCCCCCCCCCHHHCCCCCCCCCCCC
TPLVVPRTQHEAELAAIWADVLQLDVISIDANFFSSGGHSLLATRVMLRTRQHYGRDLPL
CCEECCCCCHHHHHHHHHHHHHHHEEEEEECHHHCCCCHHHHHHHHHHHHHHHHCCCCCE
RMIFEAPTIREFAALLEQQQAVSALPNLLVPIKPQGSRTPLVCVHAIAGTVGCYSELAIA
EEEECCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCEEHHHHHHHHHHHHHCEEEE
LNPEQPVYALQAPGIDGGTTHAKVEAIAQDYCQALRQLQPQGPYRLAGWSFGGLVALEMA
ECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
RQLQLAGEQVSMLSLIDSFLAEPTPDPFPLIQSFAADLFADVDPLAAQQIDWPAIVVLPA
HHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEECC
EQQLAALYQQAQQAGLIDRDLPFDLAQRLYAVFTSHAHAIQAYQPAIYLGEAQLLQAQAN
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHCCC
PAAARRWQAVIPNLHIQVIGGDHISILRQPHVHGLANAIEQRT
HHHHHHHHHHCCCCEEEEECCCCEEECCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA