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The map label for this gene is ectB [H]

Identifier: 159898609

GI number: 159898609

Start: 2600725

End: 2602014

Strand: Reverse

Name: ectB [H]

Synonym: Haur_2088

Alternate gene names: 159898609

Gene position: 2602014-2600725 (Counterclockwise)

Preceding gene: 159898610

Following gene: 159898608

Centisome position: 41.0

GC content: 50.93

Gene sequence:

>1290_bases
ATGCAACGTGAAATAACCACGATCAATACCACCGCGTTCGACCAATACGAATCCAATGTGCGCTCCTATTGCCGTTCGTT
TCCAACGGTGTTTCGCCAAGCCCAAGGCTCGCTGCTGTATAACGAGCAACAACGTGCCTATATCGATTTCTTTGCTGGGG
CGGGAGCGCTAAACTACGGCCATAATAACCCGCAGATCAAACAAGCCCTGCTCGACTACCTCGAATCCGACCAAATTATC
CATGGCTTGGATATGTATACTAGTGCCAAACGCAGCTTTTTGGAGCGGTTTAATCAGGTTATTTTAGCGCCACGCAACTT
GCCCTACAAAGTTCAATTTTGTGGGCCAACTGGTGCAAATGCGGTCGAGGCGGCGCTAAAACTGGCGCGAAAAGTCACGG
GTCGCACGAGCGTGATCAGTTTTATGGGTGGCTATCATGGCTTGTCGCTGGGTGGGTTAGCAGTCACGGGCAATGCCGAG
CATCGTGCTGCCGCTGGTGTGCCACTGGCTCACACCAACTTTTTGCCCTATCCTCGTGGCCCATTAGCGGCAATCGACTC
GTTGCACTATCTCGAAACCGTCTTGACCGACACCCATTCTGGCTTCGATAAACCAGCGGCGATCATCCTAGAGACAATTC
AGGCCGAAGGCGGCATTTACGTTGCCCCAACCGAATGGCTGCAAGGATTGCGACACCTCTGTGATCGCCATGGCATTGTG
CTGATCTGCGATGATATTCAGGTTGGTTGTGGTCGGACTGGCAGCTTTTTCTCGTTTGAGGCGGCTGGAATTGTGCCCGA
TTTAGTCACGCTTTCCAAGTCGATTAGTGGTTATGGCTTACCCATGGCGCTGGTCTTGATCAAGGCTGAATATGATCAAT
GGCAGCCAGCCGAGCATACTGGCACATTTCGTGGTAATCAATTGGCATTTGTAGGGGCAACTGCTGCGCTCGATTATTGG
CAAACTGATGCCTTCAGTAGCTCAATTCAGGCACTTGCCCAGCAACTCGAAAGCTTTTTGCAAACCCAGATAGTGCCGCT
CGATCCGCGCTTGGCAATTCGTGGTAAAGGCTTGGTTTGGGGGATTGATTTTGCCGAACTTGGCCCAACCGCTTCGAAAA
CGATTATGCAAGAATGTTTTGCCCAAGGGTTAATTATCGAGCGGGTTGGTCGTGGCGATAGTGTGCTGAAAATCATGCCG
CCATTAACCATCGATTCAGCCTTGCTCGCTCAAGGTTGTGCCATTCTGCAACAGGCGATTCAAACCTATTTGGCAAGTAC
AAAGGAATAA

Upstream 100 bases:

>100_bases
TATCGGCACAATTGTTGGTATGTTCAAGCAATCTTCTATAGCTCTTAGTTGTTAAACCAAATCAACCATAGCCAATAACC
TTATACAAGGAATATCATCA

Downstream 100 bases:

>100_bases
GCATGCAGTTTCCGCTAGCGCGTTATCGTCGTTTACTGGCAACCTATCTCAAGCCACAGCGTGGGCGGGTGCTCGGCTTA
GGATGCTTGGTTTTTCTGGG

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: DABA aminotransferase; Diaminobutyrate--2-oxoglutarate aminotransferase; L-2,4-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MQREITTINTTAFDQYESNVRSYCRSFPTVFRQAQGSLLYNEQQRAYIDFFAGAGALNYGHNNPQIKQALLDYLESDQII
HGLDMYTSAKRSFLERFNQVILAPRNLPYKVQFCGPTGANAVEAALKLARKVTGRTSVISFMGGYHGLSLGGLAVTGNAE
HRAAAGVPLAHTNFLPYPRGPLAAIDSLHYLETVLTDTHSGFDKPAAIILETIQAEGGIYVAPTEWLQGLRHLCDRHGIV
LICDDIQVGCGRTGSFFSFEAAGIVPDLVTLSKSISGYGLPMALVLIKAEYDQWQPAEHTGTFRGNQLAFVGATAALDYW
QTDAFSSSIQALAQQLESFLQTQIVPLDPRLAIRGKGLVWGIDFAELGPTASKTIMQECFAQGLIIERVGRGDSVLKIMP
PLTIDSALLAQGCAILQQAIQTYLASTKE

Sequences:

>Translated_429_residues
MQREITTINTTAFDQYESNVRSYCRSFPTVFRQAQGSLLYNEQQRAYIDFFAGAGALNYGHNNPQIKQALLDYLESDQII
HGLDMYTSAKRSFLERFNQVILAPRNLPYKVQFCGPTGANAVEAALKLARKVTGRTSVISFMGGYHGLSLGGLAVTGNAE
HRAAAGVPLAHTNFLPYPRGPLAAIDSLHYLETVLTDTHSGFDKPAAIILETIQAEGGIYVAPTEWLQGLRHLCDRHGIV
LICDDIQVGCGRTGSFFSFEAAGIVPDLVTLSKSISGYGLPMALVLIKAEYDQWQPAEHTGTFRGNQLAFVGATAALDYW
QTDAFSSSIQALAQQLESFLQTQIVPLDPRLAIRGKGLVWGIDFAELGPTASKTIMQECFAQGLIIERVGRGDSVLKIMP
PLTIDSALLAQGCAILQQAIQTYLASTKE
>Mature_429_residues
MQREITTINTTAFDQYESNVRSYCRSFPTVFRQAQGSLLYNEQQRAYIDFFAGAGALNYGHNNPQIKQALLDYLESDQII
HGLDMYTSAKRSFLERFNQVILAPRNLPYKVQFCGPTGANAVEAALKLARKVTGRTSVISFMGGYHGLSLGGLAVTGNAE
HRAAAGVPLAHTNFLPYPRGPLAAIDSLHYLETVLTDTHSGFDKPAAIILETIQAEGGIYVAPTEWLQGLRHLCDRHGIV
LICDDIQVGCGRTGSFFSFEAAGIVPDLVTLSKSISGYGLPMALVLIKAEYDQWQPAEHTGTFRGNQLAFVGATAALDYW
QTDAFSSSIQALAQQLESFLQTQIVPLDPRLAIRGKGLVWGIDFAELGPTASKTIMQECFAQGLIIERVGRGDSVLKIMP
PLTIDSALLAQGCAILQQAIQTYLASTKE

Specific function: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate [H]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=419, Percent_Identity=26.9689737470167, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI284507298, Length=316, Percent_Identity=28.7974683544304, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI13994255, Length=435, Percent_Identity=24.5977011494253, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI37574042, Length=409, Percent_Identity=26.6503667481663, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI24119277, Length=426, Percent_Identity=26.7605633802817, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI226442709, Length=369, Percent_Identity=27.3712737127371, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI226442705, Length=319, Percent_Identity=27.8996865203762, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI188536080, Length=285, Percent_Identity=23.1578947368421, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI38679950, Length=285, Percent_Identity=23.1578947368421, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI38679946, Length=285, Percent_Identity=23.1578947368421, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789016, Length=410, Percent_Identity=33.4146341463415, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1787560, Length=403, Percent_Identity=33.4987593052109, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1789759, Length=430, Percent_Identity=29.7674418604651, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI145693181, Length=414, Percent_Identity=30.9178743961353, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1788044, Length=437, Percent_Identity=27.6887871853547, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1786991, Length=439, Percent_Identity=26.879271070615, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1786349, Length=393, Percent_Identity=26.7175572519084, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32564660, Length=429, Percent_Identity=26.5734265734266, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI25144271, Length=408, Percent_Identity=24.5098039215686, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI25144274, Length=263, Percent_Identity=26.9961977186312, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71992977, Length=439, Percent_Identity=23.4624145785877, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17541228, Length=181, Percent_Identity=32.5966850828729, Blast_Score=78, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6324432, Length=421, Percent_Identity=27.5534441805226, Blast_Score=153, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6323470, Length=424, Percent_Identity=28.7735849056604, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324386, Length=430, Percent_Identity=23.953488372093, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28574759, Length=436, Percent_Identity=28.2110091743119, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI161085790, Length=439, Percent_Identity=27.1070615034169, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21357415, Length=407, Percent_Identity=24.3243243243243, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356575, Length=415, Percent_Identity=23.855421686747, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI281366494, Length=283, Percent_Identity=23.321554770318, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24667139, Length=283, Percent_Identity=23.321554770318, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24667143, Length=283, Percent_Identity=23.321554770318, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR012773
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 46742; Mature: 46742

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00599 AA_TRANSFER_CLASS_2 ; PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQREITTINTTAFDQYESNVRSYCRSFPTVFRQAQGSLLYNEQQRAYIDFFAGAGALNYG
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHEEEEHHCCCEECCC
HNNPQIKQALLDYLESDQIIHGLDMYTSAKRSFLERFNQVILAPRNLPYKVQFCGPTGAN
CCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCCH
AVEAALKLARKVTGRTSVISFMGGYHGLSLGGLAVTGNAEHRAAAGVPLAHTNFLPYPRG
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCEEEECCCCCHHHCCCCEECCCCCCCCCC
PLAAIDSLHYLETVLTDTHSGFDKPAAIILETIQAEGGIYVAPTEWLQGLRHLCDRHGIV
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCEE
LICDDIQVGCGRTGSFFSFEAAGIVPDLVTLSKSISGYGLPMALVLIKAEYDQWQPAEHT
EEECCCEECCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCC
GTFRGNQLAFVGATAALDYWQTDAFSSSIQALAQQLESFLQTQIVPLDPRLAIRGKGLVW
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEE
GIDFAELGPTASKTIMQECFAQGLIIERVGRGDSVLKIMPPLTIDSALLAQGCAILQQAI
ECCHHHCCCCHHHHHHHHHHHCCCCEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
QTYLASTKE
HHHHHCCCC
>Mature Secondary Structure
MQREITTINTTAFDQYESNVRSYCRSFPTVFRQAQGSLLYNEQQRAYIDFFAGAGALNYG
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHEEEEHHCCCEECCC
HNNPQIKQALLDYLESDQIIHGLDMYTSAKRSFLERFNQVILAPRNLPYKVQFCGPTGAN
CCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCCH
AVEAALKLARKVTGRTSVISFMGGYHGLSLGGLAVTGNAEHRAAAGVPLAHTNFLPYPRG
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCEEEECCCCCHHHCCCCEECCCCCCCCCC
PLAAIDSLHYLETVLTDTHSGFDKPAAIILETIQAEGGIYVAPTEWLQGLRHLCDRHGIV
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCEE
LICDDIQVGCGRTGSFFSFEAAGIVPDLVTLSKSISGYGLPMALVLIKAEYDQWQPAEHT
EEECCCEECCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCC
GTFRGNQLAFVGATAALDYWQTDAFSSSIQALAQQLESFLQTQIVPLDPRLAIRGKGLVW
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEE
GIDFAELGPTASKTIMQECFAQGLIIERVGRGDSVLKIMPPLTIDSALLAQGCAILQQAI
ECCHHHCCCCHHHHHHHHHHHCCCCEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
QTYLASTKE
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA