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The map label for this gene is rsbRA [H]

Identifier: 159898486

GI number: 159898486

Start: 2397262

End: 2398878

Strand: Direct

Name: rsbRA [H]

Synonym: Haur_1962

Alternate gene names: 159898486

Gene position: 2397262-2398878 (Clockwise)

Preceding gene: 159898484

Following gene: 159898488

Centisome position: 37.77

GC content: 50.34

Gene sequence:

>1617_bases
ATGGGAAGCAATCTGGATCAGGATGGGGCGCAACCACCTCGCGACGTTCAGCAGACGATTGACAGCTTGCGGGCACAACT
CTTAATCTATGAACAAATTTTAGATACACTCCCCGATTTGATTTTATACAAAGGCCCAGGCTCGCATATTCGCTATGCCA
ATCGCGCTTTTCGCGATTACTATGGCATGGACAAGCAGCAGCTCCAAGATGTGATCGATGCCGATTTCAATCAGCCTGAT
TATACCCAGCAGTATATTCGTGATGATGCGCAGGTGTTTCAAACTGGTCAAACATTAGTGATCGAGTGCGAGCCAGTCAC
CCATCATAGCGGTGATGTCCATCTATTTGCGACCACCAAGCATGCAATTCGCAGTCACGAGGGGGAAATCATTGGCACGG
TTGGCATCTCACGCGATCTGAGCACAACCAGCGAATCTGCGGCGGTGCGCACTAATAACGAGATTCGTTTGCAGCGGATT
ATCGACAACGTGCCTGGCATGGTCTATCAATTATTGCTGAATCCCGATACAACCATCAGCTTTCCATTTGTCAGCACAGG
CAGTCGCGATCTGTATGCCCACGAGCCAGAAGCGATTATGCATCAGGCCAACATTGTGACGGAGGCGATGCATCCTGCCG
ACCGTAGCCGTTTTCAGGAAGGAATGTTGGCTTCGGCCCAAAGCCTTACTGCTTGGCATTGGGAAGGCCGGATTGTGATC
AATGGCCACGAGCGTTGGTTGCAAAGCGCCTCGCGACCTAGCAAATTGGATAATGGAGCCATTTTGTGGGATGGTGTGTT
GCTGGATATTACCCAGCAAAAGCAAGCCGAAGCACTGTTAATCCGCTTTGATAGTATTTTAAGCGCGACCCCTGATCTGG
TAATGATTGCTGATGCTGCTGGTCAGATCCAATATCTCAATCCAGCCGCTCGCCACGTTATCCAATCCGAACCAACCACA
GCAGCTGAGCCATTAACGTGGCAACAGCTTTACCGCACCGCCCCCGACCAAGCTTGGATTAGCCAAACCTTGCAGCATGC
CCAAACCCATGGCTCATGGATGGGCGATTATCATTTGCAAACGGCCCAAGGCAGCCAGCTGCCGCTGCATTATCAAGTGT
TGTGTCATTATGATTATGATCAGCAGCCCAGCTTTTTTTCATTGATCGCCCACGATATTCGCGATCAGCAACAGGCTGAT
GCCGAACGTCAGCGCTTGCACGAAGAAATTATTCGGACTCAACAGCAAGCCTTGATTGATCTTTCAACTCCATTGATCCC
AATTGCGGATACGGTTGTGTTGATGCCCTTGATTGGTAGCGTTGATACGGCGCGGGCGCAGCGCTTGATGGAAACCTTGT
TGGAAGGCGTGCATACTCACAAAGCCCAGATGGCGATCGTTGATGTGACGGGTGTTCCGATTATGGATACCCAGGTGGCT
GGATTACTCATTCGGGCCGCTACAAGTGTACAATTGCTTGGTGCTCAGGTTATTATCACCGGCATTCGCCCCGAGTTGGC
CCAAACCCTCGTGACCTTGGGCATTGATTTCCGATCCATCATTACCCAAAGTAGTCTGCAACAAGGCATTACCTATGCAA
TCCAATCACTAAAATAG

Upstream 100 bases:

>100_bases
TATCCAAATTTAGCACGATGTATGCTACCATAGCAGGAATCGCCGCACGTTCAAGCAGTTCAGCCAATAGTATCTCGGTA
TCCTTTGGGGGAGGCCCATA

Downstream 100 bases:

>100_bases
CTGTGTTTTGAAGGTTTTCTTGCAAAGGCCTGCGATCAACCATAATCGCAGGCCTTTAATTTAGGCTCCGCTGGGGGCGA
AGGTTGCAGCGGATGGTTGG

Product: putative PAS/PAC sensor protein

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 538; Mature: 537

Protein sequence:

>538_residues
MGSNLDQDGAQPPRDVQQTIDSLRAQLLIYEQILDTLPDLILYKGPGSHIRYANRAFRDYYGMDKQQLQDVIDADFNQPD
YTQQYIRDDAQVFQTGQTLVIECEPVTHHSGDVHLFATTKHAIRSHEGEIIGTVGISRDLSTTSESAAVRTNNEIRLQRI
IDNVPGMVYQLLLNPDTTISFPFVSTGSRDLYAHEPEAIMHQANIVTEAMHPADRSRFQEGMLASAQSLTAWHWEGRIVI
NGHERWLQSASRPSKLDNGAILWDGVLLDITQQKQAEALLIRFDSILSATPDLVMIADAAGQIQYLNPAARHVIQSEPTT
AAEPLTWQQLYRTAPDQAWISQTLQHAQTHGSWMGDYHLQTAQGSQLPLHYQVLCHYDYDQQPSFFSLIAHDIRDQQQAD
AERQRLHEEIIRTQQQALIDLSTPLIPIADTVVLMPLIGSVDTARAQRLMETLLEGVHTHKAQMAIVDVTGVPIMDTQVA
GLLIRAATSVQLLGAQVIITGIRPELAQTLVTLGIDFRSIITQSSLQQGITYAIQSLK

Sequences:

>Translated_538_residues
MGSNLDQDGAQPPRDVQQTIDSLRAQLLIYEQILDTLPDLILYKGPGSHIRYANRAFRDYYGMDKQQLQDVIDADFNQPD
YTQQYIRDDAQVFQTGQTLVIECEPVTHHSGDVHLFATTKHAIRSHEGEIIGTVGISRDLSTTSESAAVRTNNEIRLQRI
IDNVPGMVYQLLLNPDTTISFPFVSTGSRDLYAHEPEAIMHQANIVTEAMHPADRSRFQEGMLASAQSLTAWHWEGRIVI
NGHERWLQSASRPSKLDNGAILWDGVLLDITQQKQAEALLIRFDSILSATPDLVMIADAAGQIQYLNPAARHVIQSEPTT
AAEPLTWQQLYRTAPDQAWISQTLQHAQTHGSWMGDYHLQTAQGSQLPLHYQVLCHYDYDQQPSFFSLIAHDIRDQQQAD
AERQRLHEEIIRTQQQALIDLSTPLIPIADTVVLMPLIGSVDTARAQRLMETLLEGVHTHKAQMAIVDVTGVPIMDTQVA
GLLIRAATSVQLLGAQVIITGIRPELAQTLVTLGIDFRSIITQSSLQQGITYAIQSLK
>Mature_537_residues
GSNLDQDGAQPPRDVQQTIDSLRAQLLIYEQILDTLPDLILYKGPGSHIRYANRAFRDYYGMDKQQLQDVIDADFNQPDY
TQQYIRDDAQVFQTGQTLVIECEPVTHHSGDVHLFATTKHAIRSHEGEIIGTVGISRDLSTTSESAAVRTNNEIRLQRII
DNVPGMVYQLLLNPDTTISFPFVSTGSRDLYAHEPEAIMHQANIVTEAMHPADRSRFQEGMLASAQSLTAWHWEGRIVIN
GHERWLQSASRPSKLDNGAILWDGVLLDITQQKQAEALLIRFDSILSATPDLVMIADAAGQIQYLNPAARHVIQSEPTTA
AEPLTWQQLYRTAPDQAWISQTLQHAQTHGSWMGDYHLQTAQGSQLPLHYQVLCHYDYDQQPSFFSLIAHDIRDQQQADA
ERQRLHEEIIRTQQQALIDLSTPLIPIADTVVLMPLIGSVDTARAQRLMETLLEGVHTHKAQMAIVDVTGVPIMDTQVAG
LLIRAATSVQLLGAQVIITGIRPELAQTLVTLGIDFRSIITQSSLQQGITYAIQSLK

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 60103; Mature: 59972

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSNLDQDGAQPPRDVQQTIDSLRAQLLIYEQILDTLPDLILYKGPGSHIRYANRAFRDY
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCHHHHHHHHHHH
YGMDKQQLQDVIDADFNQPDYTQQYIRDDAQVFQTGQTLVIECEPVTHHSGDVHLFATTK
HCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEECH
HAIRSHEGEIIGTVGISRDLSTTSESAAVRTNNEIRLQRIIDNVPGMVYQLLLNPDTTIS
HHHHCCCCCEEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHCCHHHHHHEECCCCEEE
FPFVSTGSRDLYAHEPEAIMHQANIVTEAMHPADRSRFQEGMLASAQSLTAWHWEGRIVI
ECEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCEEEEECCEEEE
NGHERWLQSASRPSKLDNGAILWDGVLLDITQQKQAEALLIRFDSILSATPDLVMIADAA
CCHHHHHHCCCCCCCCCCCEEEECCEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEECCC
GQIQYLNPAARHVIQSEPTTAAEPLTWQQLYRTAPDQAWISQTLQHAQTHGSWMGDYHLQ
CCEEECCHHHHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEE
TAQGSQLPLHYQVLCHYDYDQQPSFFSLIAHDIRDQQQADAERQRLHEEIIRTQQQALID
ECCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSTPLIPIADTVVLMPLIGSVDTARAQRLMETLLEGVHTHKAQMAIVDVTGVPIMDTQVA
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEHHHHH
GLLIRAATSVQLLGAQVIITGIRPELAQTLVTLGIDFRSIITQSSLQQGITYAIQSLK
HHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GSNLDQDGAQPPRDVQQTIDSLRAQLLIYEQILDTLPDLILYKGPGSHIRYANRAFRDY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCHHHHHHHHHHH
YGMDKQQLQDVIDADFNQPDYTQQYIRDDAQVFQTGQTLVIECEPVTHHSGDVHLFATTK
HCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEECH
HAIRSHEGEIIGTVGISRDLSTTSESAAVRTNNEIRLQRIIDNVPGMVYQLLLNPDTTIS
HHHHCCCCCEEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHCCHHHHHHEECCCCEEE
FPFVSTGSRDLYAHEPEAIMHQANIVTEAMHPADRSRFQEGMLASAQSLTAWHWEGRIVI
ECEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCEEEEECCEEEE
NGHERWLQSASRPSKLDNGAILWDGVLLDITQQKQAEALLIRFDSILSATPDLVMIADAA
CCHHHHHHCCCCCCCCCCCEEEECCEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEECCC
GQIQYLNPAARHVIQSEPTTAAEPLTWQQLYRTAPDQAWISQTLQHAQTHGSWMGDYHLQ
CCEEECCHHHHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEE
TAQGSQLPLHYQVLCHYDYDQQPSFFSLIAHDIRDQQQADAERQRLHEEIIRTQQQALID
ECCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSTPLIPIADTVVLMPLIGSVDTARAQRLMETLLEGVHTHKAQMAIVDVTGVPIMDTQVA
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEHHHHH
GLLIRAATSVQLLGAQVIITGIRPELAQTLVTLGIDFRSIITQSSLQQGITYAIQSLK
HHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]