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The map label for this gene is lgrB [H]

Identifier: 159898398

GI number: 159898398

Start: 2221657

End: 2226318

Strand: Direct

Name: lgrB [H]

Synonym: Haur_1874

Alternate gene names: 159898398

Gene position: 2221657-2226318 (Clockwise)

Preceding gene: 159898397

Following gene: 159898399

Centisome position: 35.01

GC content: 48.84

Gene sequence:

>4662_bases
ATGAGCGATTTTGCCAAACGCCTAGCTGCTCTTTCGCCAGAGCAACGAGCCTTGCTTGAAAAACGGCTCAACCAGAAAAA
AGCCGAACCAAACAAACAGCAGATTCCCCACGTCGAACGGCAAGGTGCAGCCTATGCCTTATCGTTTGCCCAAGAACGTT
TGTGGTTGATGTACCAACTTGATCCGCAGAGTGCGCTGTATAACGTGCCGGTCGTGATTCGCTTTGGGCCAAACTTTGAC
GTGGCCTTAGAGCAACGGGTTTTTCAGGCGATTATTGAGCGCCATGAAATTCTGCGTACCACGTTTAAAACCGTCGATCA
ACAACCAGTCCAAATGCTTGAGCCTGTGCCAGATTTTAGGCTCCCAGTGATCGATTTGCGGTCTTTTCCCGAGGAGCAGC
AAGCGTCCGAGGCCCAAAAACACACCCTTGCTGAAGCTCAAAAGCCCTTTGATTTGAGCAATGGGCCATTGTTGCGCGTG
GTTTTGCTGCGCTTAACTCATGAACATCACTTAATTATTAATTTGCACCATATTGTTTCTGACGATTGGTCGCCTGGGGT
TTTGGTCCAAGAGATTGGGGCTTTGCATCAGGCATTCAGTCAAGGCCAGCCTTCACCATTGGCTCCGTTGGCAATACAGT
ATCTTGATTTTGCCGTATGGCAGCGCCAACGCCTAAACCAGGCCAGTGTCTCCCAGCAATTGGAATATTGGCAAAACCAA
CTCTCGGGTTCATTACCCTTGTTGGCCTTGCCAACCGATCGCCCACGCCCACGGATTCAAACCTTCAACGGGGCAAAAAT
CAGTCGGCGAATGCCTGCCAGCCTACTTAAATCGCTCAAACAGTTGACTGCCCAAACTGGCGCAACCTTGTTTATGAGCG
TTTTGGCGGCCTATAAGATCTTGTTGCAGCACTATACAGGCCAAACAGATTTGCTGATTGGTACGCCAATTACCAGTCGA
ACCCGCCCTGAATTAGAGCCATTGATCGGCTGTTTTATTAATATGTTGGTCTTGCGTAGCCAACTTAATCTTGAGCAAAC
CTCCCGCGAGTTTATTCAGCAGGTGCGCCAAATGGCCTTGGATGCTTATGCCAATGCTGAAGTGCCGTTTGAGCGCTTGG
TGCAGGTGTTGCGGCCTGAGCGTAATCCGAGCTATACCCCAATTTTTCAGGCAGCCTATATTCTGCAAGATCCCCAAGAA
GCTCGTCAGAAGATGCCTGAAAATGTACTTGGTTATGCCGAGGTTGATACTGGGACTTCTAAGTTTGATTTGACCTTGGA
GATCGATGAAGTTGATGGTGAATTAGCTACAGCTTTTGTGTATAGTACTGATCTCTTCGATCAAGCAACCGTCGAACGCA
TGCTTGGGCATCTGCAACAGATTCTTGAAACCATGGTTGCTCAGCCGGATTTGCCGATTGCTGCGATTGAATTGGTTACC
AGTGCCGAACGCCAGCAATTGTTGATCGAGTGGAATGCTACTGAAACAGCCTTTGAAACAGATTTTGTTCAGCATGCAAT
TGCCCGTCACGCTCAAACCCAACCAGATCAACTGGCCTTGCGCTATGGTGATCAGCAGTATTCCTATGCTGAATTGAACC
AGCATGCTGAGCGCTTGGCGACCTATTTACAGCAATTAGGCGTAAAACCAGAATGTGTTGTTGGTTTGTGCGTTGAGCGC
ACTCCTGCAATGGTGATTGCGATTCTAGCGATTTTTAAAGCTGGCGGCCTGTTTTTGCCACTTGACCCCAGCTTTCCTGC
TGATCGTTTGGCTTATATTGTTGCCGATGCCAAGCCTTTGGTCGTGCTAACAACTGCTGCCTTAGCTGCTGAATTGCCCT
TAGAAGCTCCCCATATTGTTGCACTTGATCAAGCTTGGCATGCCCATATTCAGCAGGTTGATGCGCCAAATCATCAACTG
CAACCCAGCAATTTGGCCTATATGATTTATACCTCGGGCACGACTGGCACGCCTAAAGCGGTTTTGGTTACCCATCAAAA
TCTGTTGAATGTGTTGTTGGCAAGTCAGCAAGCGTTTGGCTTCAATCCTCGTGATGTGATGCCGTGTATTGCCCCATTCT
CATTTGATATTTTTCTGTTTGAATTGCTCAACCCATTGCTTGCTGGCGGCACATCGTGGATGCTTACCCGCGAAGAAATT
TTGGATATTGCTGGCTTGATCGAGTCGCTGGCTTCGATGAGTGTGATTCACACTGTCCCAAGTTTGATGCGTCAATTGGT
CAATGCCTTGGAAACTGAAGGCTATACTGCCGCTGCTTGTCAAAGCATTCGGATGATTTTTATTGGTGGCGATTTAGTGC
CGCCTGAATTGTTAAATGCGATGCGGCTCGCCTTTCCGCAAGCCGCAATTCATGTGTTGTATGGCCCAACCGAAGCCACG
ATTATTTGTACCAGCTATCGTGTGCCCCAACAGGGCTTGCTTGAGCGCCATTTGATTGGGCGACCACTACCAAATATGGC
GATTCGCTTGTATGACCCACAGCAAAACCTCGTACCAATTGGTATGCCAGGCGAACTGTACATCGGCGGGGCTGGGGTTA
GTCGGGGCTATTTGAATCGCTCGGAATTGACTGACGAGAAATTTGTCGAGCTTGATCAGCAGCGTTGGTATCGTACTGGC
GATTTGGCGCGTTATCAGGTTGATGGAAATCTCGAATTTTTAGGCCGCATCGATCAACAAGTTAAAATTCGTGGCTTTCG
GATTGAGCTTGGCGAAATTGAAGCAGTACTGGCGCAACATCCTAGCATTCGGGAAGCGGTGGTGGTTGCCCGTGAAGATC
TGCCTGGCGATAAGCGACTCGTAGCTTATTTGATTGCGGAATCAGAACAAATGCCGCATATTGGTGAATTACGGGCATTT
TTGCAAACCAAACTGCCTGAATATATGCTGCCTGCAGCGTTTATGGTGTTGGAGAGCCTGCCGCTGACCCGCAATGGGAA
GGTTGATCGTCAAGCGTTGCCTGTGCCGCCCACCACCCGTGAGCATTTGGCCAATCAATTTGCTGCACCAACCAATCAAC
TCGAAACGCTGCTGAGCACGATTTGGGCCGAGGTGTTGGGGCGCGAACAGGTTGGCATTCACGACAATTTCTTTGAACTC
GGCGGCGATTCGATTCTGAGTTTGCAAATTGTAGCGCGACTCAATCAGGCTGGCTATCATGTGCTAACCAAAGATATATT
TCAGTATCAAACGATTGCTGAATTGGCACAGGTGGTTTCGAGCACCACGCTGGTTGTGGCCGATCAAGGCTTGATCGAAG
GTGCCGTGCCGCTTACGCCCATTCAACAGTGGTTCTTTTGCCAAAATCTACCTAATCCACACTATTTTAATAGTATGCCA
GTGTTGCTTGAAGCGCCTGCCGAGCTTACTCAGGCTGATTTGCACTCGATCGTTGCCCAACTTTTGCAGCATCACGATGG
CCTGCGCTTGCGCTTCGAGTTGGTTGCTGACCAATGGCAACAAACCCACGGCTCGCTTGAGGCTGATTTACCACTAGCGA
TAATTGATCTCAGGGGCTTGAATCAAGGAACCCAAACCCAAACGATTGAAGCAACCGCGATTGAATACCAAACCAAACTC
GATTTGAGCACTGGCCCGCTGATTTGGTTTGTGCTATTCGAAGCAGAGTTGAGCAAGCGCCTATTAATTGTGGCGCATCA
CCTTGTATTTGATGGAATTTCGCTGCGGATTCTGTTGGAAGATTTACAAACGGCCTATGCTCAACTACAGGCAGGGCAAT
CGATTAATTTACCGCTCAAAACCAGTTCGTTCAAAACTTGGGCTTTGGCGCTTCAGGAGTATGCCCAATCACCAGAAGTC
GCCCAACAAGCCAGCTATTGGCAGACGATTCAGCATACTCAATCACCTTTGCCGCTTGATCATAGCGGTCAGGCCAATAC
TGAAGCCTCAAGCAGTATTGTCTTGGCCCGACTTGAGGTCGCAGAAACCGACGTATTGCTGAACCAATTGCCAACGCTCT
ATCATGCCAGCCTTGAAGAAGTATTGCTAACCGCTTTAGCCCAAACGATTGGCGAATGGACGTATAGCCAAAGCCTTGTG
GTTGATTTAGAAAGCCATGGCCGCGCCGAATCGATTGCTGAAAATCTCAATCTTTCGCGCACGATTGGCTGGTTTACCAG
TCTTTATCCAGTAATTTTGGATTGGACTGGCTTTGATGGGCCGCTTGAAATGCTGAAAGTGATTAAAGAAACCCTGCGCC
AAGTGCCTGAATATGGGCTTAGTTATGGCTTATGGCAGTTCAATCAACCTAATCCTAGCGCCAATTCACACGCTGAACTA
CGCTTTAATTATCTTGGTCAATTAGGGGGTGCGGCTCAAAAAGCAGCCTTTGAGTTATTGCCCCAACTTGAAGTGCCACT
GCGTGACCCTGCTAGCACGCGATCGCATGTTTTAGACGTTGATGTGGTGGTGGTGCAACAGCAATTGTGGGTGCGCTGGA
CGTATAGCAATCACTTACATGAGCCAGCCACGATTACCCAGCTTGCCGAGCGCTTTATGGCGGCATTACGCGATTTATTG
CAAGGCGATAGCGCAACTAGCGCCGCGTATGTTCCATCCGATTTCCCGATGGCAAACCTTGATCAGCAGACATTGAACTC
ACTTATGAAGAAACTTCGCTAG

Upstream 100 bases:

>100_bases
AAGATGCTGAGTTGGCAGCTTTATTGGCTGAGATTGAGCAAACCCCGCTTGATCAGGTGCAAGCCTTGTTGAATGAAACT
GCGAGTGAAGGAGGCAGTGA

Downstream 100 bases:

>100_bases
CTGAAGGAACTGGGATGAATGCAGATATTGAGGACATCTACCCACTTTCGCCGTTACAACAAGGGTTACTCTTTCATAGC
CTGTATGACCCAGATTCGGG

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1553; Mature: 1552

Protein sequence:

>1553_residues
MSDFAKRLAALSPEQRALLEKRLNQKKAEPNKQQIPHVERQGAAYALSFAQERLWLMYQLDPQSALYNVPVVIRFGPNFD
VALEQRVFQAIIERHEILRTTFKTVDQQPVQMLEPVPDFRLPVIDLRSFPEEQQASEAQKHTLAEAQKPFDLSNGPLLRV
VLLRLTHEHHLIINLHHIVSDDWSPGVLVQEIGALHQAFSQGQPSPLAPLAIQYLDFAVWQRQRLNQASVSQQLEYWQNQ
LSGSLPLLALPTDRPRPRIQTFNGAKISRRMPASLLKSLKQLTAQTGATLFMSVLAAYKILLQHYTGQTDLLIGTPITSR
TRPELEPLIGCFINMLVLRSQLNLEQTSREFIQQVRQMALDAYANAEVPFERLVQVLRPERNPSYTPIFQAAYILQDPQE
ARQKMPENVLGYAEVDTGTSKFDLTLEIDEVDGELATAFVYSTDLFDQATVERMLGHLQQILETMVAQPDLPIAAIELVT
SAERQQLLIEWNATETAFETDFVQHAIARHAQTQPDQLALRYGDQQYSYAELNQHAERLATYLQQLGVKPECVVGLCVER
TPAMVIAILAIFKAGGLFLPLDPSFPADRLAYIVADAKPLVVLTTAALAAELPLEAPHIVALDQAWHAHIQQVDAPNHQL
QPSNLAYMIYTSGTTGTPKAVLVTHQNLLNVLLASQQAFGFNPRDVMPCIAPFSFDIFLFELLNPLLAGGTSWMLTREEI
LDIAGLIESLASMSVIHTVPSLMRQLVNALETEGYTAAACQSIRMIFIGGDLVPPELLNAMRLAFPQAAIHVLYGPTEAT
IICTSYRVPQQGLLERHLIGRPLPNMAIRLYDPQQNLVPIGMPGELYIGGAGVSRGYLNRSELTDEKFVELDQQRWYRTG
DLARYQVDGNLEFLGRIDQQVKIRGFRIELGEIEAVLAQHPSIREAVVVAREDLPGDKRLVAYLIAESEQMPHIGELRAF
LQTKLPEYMLPAAFMVLESLPLTRNGKVDRQALPVPPTTREHLANQFAAPTNQLETLLSTIWAEVLGREQVGIHDNFFEL
GGDSILSLQIVARLNQAGYHVLTKDIFQYQTIAELAQVVSSTTLVVADQGLIEGAVPLTPIQQWFFCQNLPNPHYFNSMP
VLLEAPAELTQADLHSIVAQLLQHHDGLRLRFELVADQWQQTHGSLEADLPLAIIDLRGLNQGTQTQTIEATAIEYQTKL
DLSTGPLIWFVLFEAELSKRLLIVAHHLVFDGISLRILLEDLQTAYAQLQAGQSINLPLKTSSFKTWALALQEYAQSPEV
AQQASYWQTIQHTQSPLPLDHSGQANTEASSSIVLARLEVAETDVLLNQLPTLYHASLEEVLLTALAQTIGEWTYSQSLV
VDLESHGRAESIAENLNLSRTIGWFTSLYPVILDWTGFDGPLEMLKVIKETLRQVPEYGLSYGLWQFNQPNPSANSHAEL
RFNYLGQLGGAAQKAAFELLPQLEVPLRDPASTRSHVLDVDVVVVQQQLWVRWTYSNHLHEPATITQLAERFMAALRDLL
QGDSATSAAYVPSDFPMANLDQQTLNSLMKKLR

Sequences:

>Translated_1553_residues
MSDFAKRLAALSPEQRALLEKRLNQKKAEPNKQQIPHVERQGAAYALSFAQERLWLMYQLDPQSALYNVPVVIRFGPNFD
VALEQRVFQAIIERHEILRTTFKTVDQQPVQMLEPVPDFRLPVIDLRSFPEEQQASEAQKHTLAEAQKPFDLSNGPLLRV
VLLRLTHEHHLIINLHHIVSDDWSPGVLVQEIGALHQAFSQGQPSPLAPLAIQYLDFAVWQRQRLNQASVSQQLEYWQNQ
LSGSLPLLALPTDRPRPRIQTFNGAKISRRMPASLLKSLKQLTAQTGATLFMSVLAAYKILLQHYTGQTDLLIGTPITSR
TRPELEPLIGCFINMLVLRSQLNLEQTSREFIQQVRQMALDAYANAEVPFERLVQVLRPERNPSYTPIFQAAYILQDPQE
ARQKMPENVLGYAEVDTGTSKFDLTLEIDEVDGELATAFVYSTDLFDQATVERMLGHLQQILETMVAQPDLPIAAIELVT
SAERQQLLIEWNATETAFETDFVQHAIARHAQTQPDQLALRYGDQQYSYAELNQHAERLATYLQQLGVKPECVVGLCVER
TPAMVIAILAIFKAGGLFLPLDPSFPADRLAYIVADAKPLVVLTTAALAAELPLEAPHIVALDQAWHAHIQQVDAPNHQL
QPSNLAYMIYTSGTTGTPKAVLVTHQNLLNVLLASQQAFGFNPRDVMPCIAPFSFDIFLFELLNPLLAGGTSWMLTREEI
LDIAGLIESLASMSVIHTVPSLMRQLVNALETEGYTAAACQSIRMIFIGGDLVPPELLNAMRLAFPQAAIHVLYGPTEAT
IICTSYRVPQQGLLERHLIGRPLPNMAIRLYDPQQNLVPIGMPGELYIGGAGVSRGYLNRSELTDEKFVELDQQRWYRTG
DLARYQVDGNLEFLGRIDQQVKIRGFRIELGEIEAVLAQHPSIREAVVVAREDLPGDKRLVAYLIAESEQMPHIGELRAF
LQTKLPEYMLPAAFMVLESLPLTRNGKVDRQALPVPPTTREHLANQFAAPTNQLETLLSTIWAEVLGREQVGIHDNFFEL
GGDSILSLQIVARLNQAGYHVLTKDIFQYQTIAELAQVVSSTTLVVADQGLIEGAVPLTPIQQWFFCQNLPNPHYFNSMP
VLLEAPAELTQADLHSIVAQLLQHHDGLRLRFELVADQWQQTHGSLEADLPLAIIDLRGLNQGTQTQTIEATAIEYQTKL
DLSTGPLIWFVLFEAELSKRLLIVAHHLVFDGISLRILLEDLQTAYAQLQAGQSINLPLKTSSFKTWALALQEYAQSPEV
AQQASYWQTIQHTQSPLPLDHSGQANTEASSSIVLARLEVAETDVLLNQLPTLYHASLEEVLLTALAQTIGEWTYSQSLV
VDLESHGRAESIAENLNLSRTIGWFTSLYPVILDWTGFDGPLEMLKVIKETLRQVPEYGLSYGLWQFNQPNPSANSHAEL
RFNYLGQLGGAAQKAAFELLPQLEVPLRDPASTRSHVLDVDVVVVQQQLWVRWTYSNHLHEPATITQLAERFMAALRDLL
QGDSATSAAYVPSDFPMANLDQQTLNSLMKKLR
>Mature_1552_residues
SDFAKRLAALSPEQRALLEKRLNQKKAEPNKQQIPHVERQGAAYALSFAQERLWLMYQLDPQSALYNVPVVIRFGPNFDV
ALEQRVFQAIIERHEILRTTFKTVDQQPVQMLEPVPDFRLPVIDLRSFPEEQQASEAQKHTLAEAQKPFDLSNGPLLRVV
LLRLTHEHHLIINLHHIVSDDWSPGVLVQEIGALHQAFSQGQPSPLAPLAIQYLDFAVWQRQRLNQASVSQQLEYWQNQL
SGSLPLLALPTDRPRPRIQTFNGAKISRRMPASLLKSLKQLTAQTGATLFMSVLAAYKILLQHYTGQTDLLIGTPITSRT
RPELEPLIGCFINMLVLRSQLNLEQTSREFIQQVRQMALDAYANAEVPFERLVQVLRPERNPSYTPIFQAAYILQDPQEA
RQKMPENVLGYAEVDTGTSKFDLTLEIDEVDGELATAFVYSTDLFDQATVERMLGHLQQILETMVAQPDLPIAAIELVTS
AERQQLLIEWNATETAFETDFVQHAIARHAQTQPDQLALRYGDQQYSYAELNQHAERLATYLQQLGVKPECVVGLCVERT
PAMVIAILAIFKAGGLFLPLDPSFPADRLAYIVADAKPLVVLTTAALAAELPLEAPHIVALDQAWHAHIQQVDAPNHQLQ
PSNLAYMIYTSGTTGTPKAVLVTHQNLLNVLLASQQAFGFNPRDVMPCIAPFSFDIFLFELLNPLLAGGTSWMLTREEIL
DIAGLIESLASMSVIHTVPSLMRQLVNALETEGYTAAACQSIRMIFIGGDLVPPELLNAMRLAFPQAAIHVLYGPTEATI
ICTSYRVPQQGLLERHLIGRPLPNMAIRLYDPQQNLVPIGMPGELYIGGAGVSRGYLNRSELTDEKFVELDQQRWYRTGD
LARYQVDGNLEFLGRIDQQVKIRGFRIELGEIEAVLAQHPSIREAVVVAREDLPGDKRLVAYLIAESEQMPHIGELRAFL
QTKLPEYMLPAAFMVLESLPLTRNGKVDRQALPVPPTTREHLANQFAAPTNQLETLLSTIWAEVLGREQVGIHDNFFELG
GDSILSLQIVARLNQAGYHVLTKDIFQYQTIAELAQVVSSTTLVVADQGLIEGAVPLTPIQQWFFCQNLPNPHYFNSMPV
LLEAPAELTQADLHSIVAQLLQHHDGLRLRFELVADQWQQTHGSLEADLPLAIIDLRGLNQGTQTQTIEATAIEYQTKLD
LSTGPLIWFVLFEAELSKRLLIVAHHLVFDGISLRILLEDLQTAYAQLQAGQSINLPLKTSSFKTWALALQEYAQSPEVA
QQASYWQTIQHTQSPLPLDHSGQANTEASSSIVLARLEVAETDVLLNQLPTLYHASLEEVLLTALAQTIGEWTYSQSLVV
DLESHGRAESIAENLNLSRTIGWFTSLYPVILDWTGFDGPLEMLKVIKETLRQVPEYGLSYGLWQFNQPNPSANSHAELR
FNYLGQLGGAAQKAAFELLPQLEVPLRDPASTRSHVLDVDVVVVQQQLWVRWTYSNHLHEPATITQLAERFMAALRDLLQ
GDSATSAAYVPSDFPMANLDQQTLNSLMKKLR

Specific function: Activates the 3rd to 6th amino acids (Ala, D-Leu, Ala and D-Val) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 4th (D-Leu) and the 6th (D-Val) amino acids [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI187761345, Length=534, Percent_Identity=25.6554307116105, Blast_Score=128, Evalue=5e-29,
Organism=Homo sapiens, GI187761343, Length=534, Percent_Identity=25.6554307116105, Blast_Score=128, Evalue=5e-29,
Organism=Homo sapiens, GI156151445, Length=558, Percent_Identity=22.2222222222222, Blast_Score=117, Evalue=1e-25,
Organism=Homo sapiens, GI28416953, Length=557, Percent_Identity=24.4165170556553, Blast_Score=115, Evalue=4e-25,
Organism=Homo sapiens, GI45580730, Length=429, Percent_Identity=25.8741258741259, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI115511026, Length=540, Percent_Identity=22.2222222222222, Blast_Score=110, Evalue=1e-23,
Organism=Homo sapiens, GI12669909, Length=502, Percent_Identity=23.7051792828685, Blast_Score=106, Evalue=2e-22,
Organism=Homo sapiens, GI4758332, Length=502, Percent_Identity=23.7051792828685, Blast_Score=105, Evalue=3e-22,
Organism=Homo sapiens, GI42544132, Length=504, Percent_Identity=21.8253968253968, Blast_Score=98, Evalue=6e-20,
Organism=Homo sapiens, GI38505220, Length=497, Percent_Identity=22.3340040241449, Blast_Score=98, Evalue=8e-20,
Organism=Homo sapiens, GI157311624, Length=550, Percent_Identity=22, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI157311622, Length=550, Percent_Identity=22, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI58082049, Length=549, Percent_Identity=21.8579234972678, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI122937307, Length=501, Percent_Identity=21.9560878243513, Blast_Score=83, Evalue=2e-15,
Organism=Escherichia coli, GI1786801, Length=671, Percent_Identity=32.0417287630402, Blast_Score=296, Evalue=7e-81,
Organism=Escherichia coli, GI145693145, Length=543, Percent_Identity=26.7034990791897, Blast_Score=135, Evalue=2e-32,
Organism=Escherichia coli, GI1788107, Length=546, Percent_Identity=25.0915750915751, Blast_Score=122, Evalue=2e-28,
Organism=Escherichia coli, GI1790505, Length=552, Percent_Identity=23.5507246376812, Blast_Score=117, Evalue=6e-27,
Organism=Escherichia coli, GI1786810, Length=514, Percent_Identity=26.6536964980545, Blast_Score=112, Evalue=2e-25,
Organism=Escherichia coli, GI1788595, Length=498, Percent_Identity=26.7068273092369, Blast_Score=101, Evalue=4e-22,
Organism=Escherichia coli, GI221142682, Length=530, Percent_Identity=22.6415094339623, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17550940, Length=1048, Percent_Identity=22.5190839694656, Blast_Score=173, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI17556356, Length=1128, Percent_Identity=23.0496453900709, Blast_Score=152, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71994690, Length=524, Percent_Identity=23.0916030534351, Blast_Score=119, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI71994694, Length=524, Percent_Identity=23.0916030534351, Blast_Score=119, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71994703, Length=524, Percent_Identity=23.0916030534351, Blast_Score=119, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32563687, Length=503, Percent_Identity=23.2604373757455, Blast_Score=111, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17557194, Length=505, Percent_Identity=23.7623762376238, Blast_Score=109, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17538037, Length=546, Percent_Identity=23.2600732600733, Blast_Score=108, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17558820, Length=506, Percent_Identity=24.5059288537549, Blast_Score=108, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17560140, Length=494, Percent_Identity=22.2672064777328, Blast_Score=108, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17531443, Length=519, Percent_Identity=21.5799614643545, Blast_Score=102, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71996755, Length=492, Percent_Identity=22.9674796747967, Blast_Score=97, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17559526, Length=368, Percent_Identity=23.3695652173913, Blast_Score=94, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI25147511, Length=339, Percent_Identity=25.3687315634218, Blast_Score=91, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17560308, Length=379, Percent_Identity=24.2744063324538, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71985884, Length=376, Percent_Identity=23.936170212766, Blast_Score=86, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32564420, Length=370, Percent_Identity=24.3243243243243, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32564422, Length=370, Percent_Identity=24.3243243243243, Blast_Score=72, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=773, Percent_Identity=24.8382923673997, Blast_Score=200, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6319699, Length=381, Percent_Identity=25.1968503937008, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24648676, Length=645, Percent_Identity=28.062015503876, Blast_Score=206, Evalue=8e-53,
Organism=Drosophila melanogaster, GI24581924, Length=517, Percent_Identity=23.9845261121857, Blast_Score=125, Evalue=2e-28,
Organism=Drosophila melanogaster, GI18859661, Length=510, Percent_Identity=22.7450980392157, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24656500, Length=501, Percent_Identity=24.5508982035928, Blast_Score=99, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24582852, Length=499, Percent_Identity=25.8517034068136, Blast_Score=99, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21356947, Length=479, Percent_Identity=21.7118997912317, Blast_Score=94, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21355181, Length=507, Percent_Identity=22.6824457593688, Blast_Score=92, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24648260, Length=476, Percent_Identity=21.6386554621849, Blast_Score=81, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21356441, Length=491, Percent_Identity=21.9959266802444, Blast_Score=78, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21358303, Length=491, Percent_Identity=20.3665987780041, Blast_Score=76, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 173799; Mature: 173668

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFAKRLAALSPEQRALLEKRLNQKKAEPNKQQIPHVERQGAAYALSFAQERLWLMYQL
CCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHCCCHHHCCCHHHHHHHHCCEEEEEEE
DPQSALYNVPVVIRFGPNFDVALEQRVFQAIIERHEILRTTFKTVDQQPVQMLEPVPDFR
CCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCC
LPVIDLRSFPEEQQASEAQKHTLAEAQKPFDLSNGPLLRVVLLRLTHEHHLIINLHHIVS
CCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEEHHHHC
DDWSPGVLVQEIGALHQAFSQGQPSPLAPLAIQYLDFAVWQRQRLNQASVSQQLEYWQNQ
CCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LSGSLPLLALPTDRPRPRIQTFNGAKISRRMPASLLKSLKQLTAQTGATLFMSVLAAYKI
HCCCCCEEECCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQHYTGQTDLLIGTPITSRTRPELEPLIGCFINMLVLRSQLNLEQTSREFIQQVRQMAL
HHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
DAYANAEVPFERLVQVLRPERNPSYTPIFQAAYILQDPQEARQKMPENVLGYAEVDTGTS
HHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHCCCHHHCCCEEECCCCC
KFDLTLEIDEVDGELATAFVYSTDLFDQATVERMLGHLQQILETMVAQPDLPIAAIELVT
EEEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
SAERQQLLIEWNATETAFETDFVQHAIARHAQTQPDQLALRYGDQQYSYAELNQHAERLA
HHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHH
TYLQQLGVKPECVVGLCVERTPAMVIAILAIFKAGGLFLPLDPSFPADRLAYIVADAKPL
HHHHHHCCCCHHHEEEHHCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHEEEEECCCCE
VVLTTAALAAELPLEAPHIVALDQAWHAHIQQVDAPNHQLQPSNLAYMIYTSGTTGTPKA
EEEEHHHHHHHCCCCCCCEEEECHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCE
VLVTHQNLLNVLLASQQAFGFNPRDVMPCIAPFSFDIFLFELLNPLLAGGTSWMLTREEI
EEEEHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEHHHH
LDIAGLIESLASMSVIHTVPSLMRQLVNALETEGYTAAACQSIRMIFIGGDLVPPELLNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEEEEEECCCCCCHHHHHH
MRLAFPQAAIHVLYGPTEATIICTSYRVPQQGLLERHLIGRPLPNMAIRLYDPQQNLVPI
HHHHCCHHHEEEEECCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEE
GMPGELYIGGAGVSRGYLNRSELTDEKFVELDQQRWYRTGDLARYQVDGNLEFLGRIDQQ
CCCCCEEEECCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCE
VKIRGFRIELGEIEAVLAQHPSIREAVVVAREDLPGDKRLVAYLIAESEQMPHIGELRAF
EEEEEEEEEHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHH
LQTKLPEYMLPAAFMVLESLPLTRNGKVDRQALPVPPTTREHLANQFAAPTNQLETLLST
HHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
IWAEVLGREQVGIHDNFFELGGDSILSLQIVARLNQAGYHVLTKDIFQYQTIAELAQVVS
HHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
STTLVVADQGLIEGAVPLTPIQQWFFCQNLPNPHYFNSMPVLLEAPAELTQADLHSIVAQ
CCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHH
LLQHHDGLRLRFELVADQWQQTHGSLEADLPLAIIDLRGLNQGTQTQTIEATAIEYQTKL
HHHCCCCCEEEHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEEEEEEEE
DLSTGPLIWFVLFEAELSKRLLIVAHHLVFDGISLRILLEDLQTAYAQLQAGQSINLPLK
CCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEE
TSSFKTWALALQEYAQSPEVAQQASYWQTIQHTQSPLPLDHSGQANTEASSSIVLARLEV
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEHHH
AETDVLLNQLPTLYHASLEEVLLTALAQTIGEWTYSQSLVVDLESHGRAESIAENLNLSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCHH
TIGWFTSLYPVILDWTGFDGPLEMLKVIKETLRQVPEYGLSYGLWQFNQPNPSANSHAEL
HHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCHHH
RFNYLGQLGGAAQKAAFELLPQLEVPLRDPASTRSHVLDVDVVVVQQQLWVRWTYSNHLH
HHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHEEEHHHHEEEHHHHEEEECCCCCC
EPATITQLAERFMAALRDLLQGDSATSAAYVPSDFPMANLDQQTLNSLMKKLR
CCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SDFAKRLAALSPEQRALLEKRLNQKKAEPNKQQIPHVERQGAAYALSFAQERLWLMYQL
CHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHCCCHHHCCCHHHHHHHHCCEEEEEEE
DPQSALYNVPVVIRFGPNFDVALEQRVFQAIIERHEILRTTFKTVDQQPVQMLEPVPDFR
CCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCC
LPVIDLRSFPEEQQASEAQKHTLAEAQKPFDLSNGPLLRVVLLRLTHEHHLIINLHHIVS
CCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEEHHHHC
DDWSPGVLVQEIGALHQAFSQGQPSPLAPLAIQYLDFAVWQRQRLNQASVSQQLEYWQNQ
CCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LSGSLPLLALPTDRPRPRIQTFNGAKISRRMPASLLKSLKQLTAQTGATLFMSVLAAYKI
HCCCCCEEECCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQHYTGQTDLLIGTPITSRTRPELEPLIGCFINMLVLRSQLNLEQTSREFIQQVRQMAL
HHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
DAYANAEVPFERLVQVLRPERNPSYTPIFQAAYILQDPQEARQKMPENVLGYAEVDTGTS
HHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHCCCHHHCCCEEECCCCC
KFDLTLEIDEVDGELATAFVYSTDLFDQATVERMLGHLQQILETMVAQPDLPIAAIELVT
EEEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
SAERQQLLIEWNATETAFETDFVQHAIARHAQTQPDQLALRYGDQQYSYAELNQHAERLA
HHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHH
TYLQQLGVKPECVVGLCVERTPAMVIAILAIFKAGGLFLPLDPSFPADRLAYIVADAKPL
HHHHHHCCCCHHHEEEHHCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHEEEEECCCCE
VVLTTAALAAELPLEAPHIVALDQAWHAHIQQVDAPNHQLQPSNLAYMIYTSGTTGTPKA
EEEEHHHHHHHCCCCCCCEEEECHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCE
VLVTHQNLLNVLLASQQAFGFNPRDVMPCIAPFSFDIFLFELLNPLLAGGTSWMLTREEI
EEEEHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEHHHH
LDIAGLIESLASMSVIHTVPSLMRQLVNALETEGYTAAACQSIRMIFIGGDLVPPELLNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEEEEEECCCCCCHHHHHH
MRLAFPQAAIHVLYGPTEATIICTSYRVPQQGLLERHLIGRPLPNMAIRLYDPQQNLVPI
HHHHCCHHHEEEEECCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEE
GMPGELYIGGAGVSRGYLNRSELTDEKFVELDQQRWYRTGDLARYQVDGNLEFLGRIDQQ
CCCCCEEEECCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCE
VKIRGFRIELGEIEAVLAQHPSIREAVVVAREDLPGDKRLVAYLIAESEQMPHIGELRAF
EEEEEEEEEHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHH
LQTKLPEYMLPAAFMVLESLPLTRNGKVDRQALPVPPTTREHLANQFAAPTNQLETLLST
HHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
IWAEVLGREQVGIHDNFFELGGDSILSLQIVARLNQAGYHVLTKDIFQYQTIAELAQVVS
HHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
STTLVVADQGLIEGAVPLTPIQQWFFCQNLPNPHYFNSMPVLLEAPAELTQADLHSIVAQ
CCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHH
LLQHHDGLRLRFELVADQWQQTHGSLEADLPLAIIDLRGLNQGTQTQTIEATAIEYQTKL
HHHCCCCCEEEHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEEEEEEEE
DLSTGPLIWFVLFEAELSKRLLIVAHHLVFDGISLRILLEDLQTAYAQLQAGQSINLPLK
CCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEE
TSSFKTWALALQEYAQSPEVAQQASYWQTIQHTQSPLPLDHSGQANTEASSSIVLARLEV
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEHHH
AETDVLLNQLPTLYHASLEEVLLTALAQTIGEWTYSQSLVVDLESHGRAESIAENLNLSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCHH
TIGWFTSLYPVILDWTGFDGPLEMLKVIKETLRQVPEYGLSYGLWQFNQPNPSANSHAEL
HHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCHHH
RFNYLGQLGGAAQKAAFELLPQLEVPLRDPASTRSHVLDVDVVVVQQQLWVRWTYSNHLH
HHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHEEEHHHHEEEHHHHEEEECCCCCC
EPATITQLAERFMAALRDLLQGDSATSAAYVPSDFPMANLDQQTLNSLMKKLR
CCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA